Медицина сьогодні і завтра最新文献

{"title":"Improvement of methods of diagnostics, classification of tooth enamel microfissures and of method for evaluating the effectiveness of their treatment","authors":"I.I. Zabolotnaia","doi":"10.35339/msz.2019.85.04.17","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.17","url":null,"abstract":"In clinical practice it is often diagnosed precervical lesions: wedge-shaped defect, precervical caries and fissures. The scientific research reveals results of application of an electrometric method for diagnostics of microfissures of teeth hard tissues. Use of this method will allow not only to make a pre-clinical diagnostics of the given pathology, but also to evaluate efficiency of the taken treatment-and-prophylactic measures. 16.70 % of cases the type of dental enamel fissures diagnosed before research, depending on complexity of their revealing, mismatched the received results of width of their disclosing. So, before the preparation of precervical pathology, we recommend to classify the diagnosed enamel microfissures of vestibular surface into two types: I – fissures, which are visible after using additional lighting, drying, optical systems, diagnostic dye, determining the electrical resistance, using of transillumination and other additional methods; ІІ – fissures, which are visible to the naked eye under normal lighting condition. Application of the proposed qualification of incomplete microfissures will promote to improving the effectiveness of surgical treatment of cervical lesions of teeth hard tissues.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126051438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infrared spectroscopy in the assessment of the mineral composition of kidney stones","authors":"S. Kolupayev, V. Lesovoy, E. Bereznyak","doi":"10.35339/msz.2019.85.04.01","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.01","url":null,"abstract":"As a result of infrared spectroscopy of kidney stones obtained from 59 patients with urolithiasis, a wide range of chemical compounds were identified in the samples, in which whevellite (calcium oxalate monohydrate), hydroxylapatite and uric acid were presented in the largest quantities. Monophasic stones were found in 8.4 % of patients. The two-phase, three-phase and four-phase composition of the samples was determined in 37.2 %, 42.3 % and 11.8 % of patients respectively. Carrying out infrared spectroscopy of kidney stones obtained as a result of self-passage or due to the use of surgical methods will contribute to the correct choice of an individual program for metaphylaxis of urolithiasis in different patients.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130433772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of severity and variability of psychopathology disturbances in structure mental health disorders in long-distance sailors depending on their levels of psychosocial stress","authors":"K. Kosenko","doi":"10.35339/msz.2019.85.04.10","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.10","url":null,"abstract":"Using clinical-psychopathological and psychodiagnostic methods, we studied the severity and variability of psychopathological symptoms in the structure of mental health disorders in seafarers, depending on the level of psychosocial stress they experienced, to determine the targets of personalized mental health care measures for this contingent. During 2016–2019, 110 officers of the command staff of the Maritime Merchant Navy (CMN), 90 sailors of the Maritime Merchant Navy (SMN), 70 representatives of the command staff of the Maritime Passenger Fleet (CPF) and 30 privates of the Maritime Passenger Fleet (SPF) were surveyed. All were examined by men, citizens of Ukraine. The study included the use of clinical-psychopathological and psychodiagnostic methods. In the inter-voyage period, the vast majority of long-distance sailors are either mentally healthy (30.9 % CMN, 41.1 % SMN, 42.9 % CPF, 33.3 % SPF), or have some signs of mental maladaptation (52.7 % CMN, 37.7 % SMN, 44.3 % CPF, 40.0 % SPF). Clinically delineated disorders of the neurotic register of the F43 cluster (adaptation disorders) are characterized by 26.7 % SPF, 21.1 % SMN, 16.4 % CMN and 12.8 % CPF. The severity and variability of psychopathological manifestations, in general in the sample, correspond to the neurotic level of response, however, have differences among the examined different groups. The greatest severity of symptoms of depression on the background of high levels of anxiety, hostility and psychosis is inherent in SPF, and the greatest severity of anxiety, phobic anxiety, hostility and somatization is inherent in CMN. The lowest severity of psychopathological symptoms is characteristic of CPF. The severity and variability of psychopathological manifestations is directly associated with the level of stress experienced by the subjects: with increasing stress burden, the severity of the psychopathological response increases. The identified patterns should be taken into account in the development of specific measures of psychotherapy and psychoprophylaxis for this contingent, which is the prospect of this study.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114834181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of interpersonal interaction features in patients with chronic prostatitis with different status of marriage satisfaction","authors":"V.A. Kryvytskyi","doi":"10.35339/msz.2019.85.04.11","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.11","url":null,"abstract":"The features of interpersonal interaction in patients with chronic prostatitis and their wives, to determine, in the future, the targets of medical and psychological care for this contingent were studied. 109 men with chronic prostatitis and their wives were examined. According to the criterion of presence / absence of marital satisfaction, the surveyed couples were divided into two groups. The first group included 73 (67.0 %) couples with low or reduced levels of marital satisfaction. The second included 36 (33.0 %) married couples who were satisfied with their own relationship. The comprehensive examination included, in addition to standard clinical methods, a clinical-psychological and psychodiagnostic study. By common disharmonious interpersonal patterns, which contributed to the development of marital dissatisfaction, which led to secondary trauma to spouses due to the formation of inadequate psychological response to chronic prostatitis in men and related sexual dysfunction, identified such deformations of family communication as reduction of trust, mutual understanding, ease and psychotherapy; prevalence of signs of distrustful-skeptical, straightforward-aggressive, dependent or submissive patterns of interpersonal behavior; dominance of aggression (32.9 %) or avoidance (67.1 %) as the leading strategies of psychological protection in communication. The obtained data should be taken into account when developing measures of medical and psychological assistance to married couples in which the husband has chronic prostatitis.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115031262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostics of collateral circulation during revascularization of cerebral arteries","authors":"I. Pulyaeva","doi":"10.35339/msz.2019.85.04.15","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.15","url":null,"abstract":"54 patients with acute stroke were examined and treated: 12 patients were treated by thrombolytic therapy and/or thrombectomy, 22 patients were treated by endarterectomy from the internal carotid artery, and 20 patients were treated by anticoagulant, nootropic and antiplatelet therapy. Collateral blood circulation of blood vessels and foci of cerebral ischemia in ischemic stroke were examined in all patients to select a treatment method. The effect of collateral circulation in patients with recanalization of the carotid and cerebral arteries on the outcome of acute stroke treatment was analyzed. According to such parameters of neuroimaging as a large nucleus and poor collaterals, 25 out of 54 patients did not respond to revascularizing therapy, which was proved by CT data and a slight regression of neurological deficit within 14 days. Patients with a large nucleus and poor collateral circulation do not respond to revascularization surgery. Compared groups of patients according to CT data. It was found that the level of development of collaterals was associated with better clinical results. Adequate collateral circulation can help maintain tissue viability in the absence of recanalization. The choice of revascularization method depends on the state of collateral circulation, the size of the ischemic focus (according to CT, MRI) and the duration of treatment from the onset of stroke. Diagnosis of ischemia should begin with MRI angiography on the first day or CT angiography from the second day, which will allow assessing the level of collaterals, giving an idea of ​​collateral perfusion in patients and the size of the lesion.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"270 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124376104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical-pathopsychological and psychodiagnostic specifics of comorbid adaptation disorders in people with computer addiction","authors":"Yuliia Starodubtseva","doi":"10.35339/msz.2019.85.04.14","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.14","url":null,"abstract":"The clinical-psychopathological and psychodiagnostic features of adaptation disorders combined with computer addiction were studied. A comprehensive survey of 97 people with adaptation disorders and clinically pronounced computer addiction (main group) and 62 patients with adaptation disorders without signs of addictive behavior (control group) were carried out. It was established that the clinical picture of adaptation disorders with comorbid computer addiction was characterized by depressive, anxiety, obsessive, asthenic, dysphoric, and somatic-vegetative syndrome complexes, 35.8 % of patients had carpal tunnel syndrome. Clinical manifestations of anxiety and depression on the Hospital scale, severe depressive and anxiety episodes on the Hamilton scale, high levels of situational and personal anxiety on the Spielberger–Hanin scale, excessive mental stress on the Nemchin scale are typical for people with adaptation disorders and computer addiction. It was shown that the key role in the pathopsychological mechanisms of comorbid adaptation disorders with computer addiction belongs to the de-actualization of basic personality needs, instability of the level of requirements, the dominance of game motives, the use of coping strategies aimed at distraction and emotion, application of a strategy of behavior in the form of avoidance and adaptation in a conflict situation, high level of social frustration in the areas of their own way of life, family relationships, relationships at work and the content of their work.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123904449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of changes in the cognitive sphere of patients with a primary episode of bipolar affective disorder","authors":"Yuriy Mysula","doi":"10.35339/msz.2019.85.04.13","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.13","url":null,"abstract":"153 patients with primary episode of bipolar affective disorder were divided to three groups: with prevalence of depressive symptomatology (44 men and 75 women), with prevalence of manic symptoms (15 men and 8 women) and with simultaneous presence of depressive and manic symptomatology or with rapid or severe manic symptoms (6 men and 5 women) and were examined using the Rey–Osterrieth test. It was found that they had impaired cognitive functioning whose structure and severity were related to the clinical type of the primary episode. In patients with depressive variant revealed approximately equal deterioration of test performance across all assessment vectors, while reproduction (immediate and delayed) observed synchronous deterioration of indicators, with the degree of deterioration of characteristics between copying and immediate and retarded reproduction. In the manic variant the performance of test is significantly different from the depressive variant. Patients with a manic variant showed the lowest indicators in the presence of individual elements of the figure, accuracy and diligence. At the same time, indicators for most estimation vectors are unstable, varying with immediate and delayed reproduction without some systematicity. Such features reflect on the cognitive functions of the maniac state with its acceleration of the speed of thinking, its chaos, instability of attention, difficulties of concentration and inability to productive activity. In patients with mixed episode, the Ray–Osterrieth test scores reflect complex contradictory tendencies of changes in the affective area, related to the rapid phase change and the presence of opposite affective manifestations. Quantitative values of indicators in patients of this group has an intermediate position between indicators of patients with depressive and manic variants. Common disorders inherent in patients of all groups were distortion of the integrity and symmetry of the figure, contamination of the elements of the figure and the omission of minor details. The differences in the structure and severity of cognitive impairment between men and women are not statistically significant.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123711202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroimaging as a method of «looking under the clinical threshold» of neurodegeneration","authors":"N. Voloshina, M. Chernenko, I. Voloshin-Gaponov, V. Vasilovsky, T. Negreba, A.Ye. Kostyukovskaya, P. Gaponov","doi":"10.35339/msz.2019.85.04.09","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.09","url":null,"abstract":"Adaptive properties of the nervous system and the phenomenon of neuroplasticity form the concept of a clinical threshold, due to which existing damage to the nervous system does not clinically manifest until a certain point. Clinical threshold is a complex of adaptive mechanisms based on the plastic properties of nervous tissue. High-field modern magnetic resonance tomographs provide an opportunity to look under the clinical threshold and timely prescribe or optimize therapy. Thanks to the timely conduct of magnetic resonance imaging of the brain, it is possible to identify preclinical changes in the nervous system, as well as timely identify adverse trends during the course of the disease in order to minimize damage to the nervous system. Changes in the ventricular system and subarachnoid spaces of the brain in patients with multiple sclerosis and Wilson–Konovalov’s disease were described. Changes were revealed that indicate the presence of atrophic changes characteristic of both demyelinating and neurodegenerative pathologies. Progressive atrophic changes in the brain with a stable clinical picture may serve as a sign of the loss of a neurological reserve. The phenomena of rapidly increasing atrophy of the brain, increasing atrophy of the corpus callosum and cerebellum in the early stages of the pathological process are unfavorable prognostic signs of both multiple sclerosis and Wilson–Konovalov’s disease. Timely assessment of the severity of atrophy can help in deciding on a drug change, a complex of intensive neuroprotective measures, and to personify therapy.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134189935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cryopreservation of human spermatozoa with penetrating and non-penetrating cryoprotectants","authors":"E. Pavlovich, G. Gapon, T. Yurchuk, M. Petrushko","doi":"10.35339/msz.2019.85.04.04","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.04","url":null,"abstract":"Сryopreserved spermatozoa are widely used in infertility treatment by assisted reproductive technologies. However, the spermatozoa survival rate remains low in patients with oligoastenoteratozoospermia. Therefore the development of effective cryopreservation methods for spermatozoa from pathospermia is relevant. The effectiveness of cryopreservation spermatozoa from oligoastenoteratozoospermia man using penetrating and non-penetrating cryoprotectants was compared. Sperm motility, viability and morphological characteristics were evaluated after cryopreservation with glycerol and polyvinylpyrrolidone. The average number of spermatozoa count in fresh ejaculate was (11.0±0.2) mln/ml. After isolation of active motile fraction the number of cells was (3.8±0.3) mln/ml and (84.3±8.4) % from them were motile (group 3). (78.8±6.6) % of spermatozoa cryopreserved with glycerol (group 1) and (41.4±8.1) % cryopreserved with polyvinylpyrrolidone (group 2) remained active motile. The spermatozoa viability after cryopreservation was (82.1±8.6) % and (89.6±8.6) % in group 1 and 2, respectively. Despite the high rate of spermatozoa survival in group 1 the number of motile cells decreased to (27.3±4.8) % after cryoprotectant removing stage. Morphological analysis revealed that the incidence of spermatozoa head abnormalities was (25.97±2.67), (19.21±2.67) and (20.57±1.19) % in group 1–3, respectively. The differences of spermatozoa midpiece and tail abnormalities in the study groups were statistically insignificant. The use of polyvinylpyrrolidone as a cryoprotectant allows preserving 90 % of survived spermatozoa from oligoastenoteratozoospermia men after freeze/thawing. The set of spermatozoa head, neck and midpiece abnormalities is significantly lower after cryopreservation with polyvinylpyrrolidone compared with routine method with glycerol. Two-stage spermatozoa cryopreservation method with polyvinylpyrrolidone is promising for assisted reproductive technologies since spermatozoa can be used immediately after warming for oocyte fertilization without cryoprotectant removing step.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129126940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of the level of insulin-like growth factor-I and endostatin in blood serum on the lipid profile indicators in patients with acute myocardial infarction and obesity","authors":"D.V. Martovitskyi","doi":"10.35339/msz.2019.85.04.07","DOIUrl":"https://doi.org/10.35339/msz.2019.85.04.07","url":null,"abstract":"The levels of insulin-like growth factor I and endostatin in the blood serum and their relationship with lipid profile were investigated in patients with acute myocardial infarction and obesity. The object of the study was 105 patients. All patients were divided into two groups: group 1 consisted of patients with AMI and concomitant obesity (n=60), group 2 consisted of AMI patients without obesity (n=45). The control group consisted of 20 practically healthy people. The average age of patients in group 1 was (67.44±1.34) years old, and in group 2 was (66.85±1.72) years old. The content of IGF-I and endostatin was determined by the enzyme immunoassay. To determine IGF-I, an enzyme-linked immunosorbent assay was used using the Human Insulin like growth factor-I ELISA Kit (MEDIAGNOST, Germany). The endostatin level was determined by the enzyme immunoassay using the Endostatin Elisa Kit (BIOMEDICA, Austria). The biochemical study included the determination of the level of TC and HDL, carried out by the peroxidase method using a set of reagents «Cholesterol Liquicolor» from «Human» (Germany) in blood serum stabilized with heparin. The obtained correlations indicate that an increase in the level of endostatin in the blood serum is significantly associated with an increase in the levels of TC, LDL, TG, CA and a decrease in HDL. Also, reliable data were obtained on the feedback between IGF-I and the level of TC, LDL, TG and CA, as well as a direct relationship between the indicators of IGF-I and HDL. The data obtained indicate that endostatin as a marker of angiogenesis is associated with obesity and dyslipidemia, and also indicate the anti-inflammatory and antioxidant properties of IGF-I under conditions of high autoimmune activity.","PeriodicalId":404961,"journal":{"name":"Медицина сьогодні і завтра","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128056786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}