Journal of Advanced Lung Health最新文献

{"title":"Long COVID and beyond: Persistence of symptoms 1 year after COVID-19 infection","authors":"R. Chetambath","doi":"10.4103/jalh.jalh_11_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_11_22","url":null,"abstract":"","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127814011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do not miss the forest for the trees – Clinicoradiological quiz","authors":"Nitesh Gupta, A. Mahendran, N. Gupta, P. Ish","doi":"10.4103/jalh.jalh_2_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_2_22","url":null,"abstract":"Abstract-Right hypochondrium pain with air-fluid level in chest X-ray can have a long list of differential diagnosis. A meticulous evaluation of history with appropriate investigations can help make the correct diagnosis.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129401271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical profile and diagnosis of tracheal bronchus among patients undergoing fiberoptic bronchoscopy in a tertiary level health facility","authors":"Sanjeev Shivashankaran, SourabhM Prakash, KS Shyvin, Sreelakshmi Kesavan, R. Chetambath","doi":"10.4103/jalh.jalh_17_21","DOIUrl":"https://doi.org/10.4103/jalh.jalh_17_21","url":null,"abstract":"Background: Tracheobronchial anomalies are rare clinical entities and often asymptomatic in nature. Some patients may experience symptoms such as cough, recurrent pneumonia, or hemoptysis. Tracheal bronchus is one of the rarer forms of tracheobronchial anomalies, which may be seen during routine bronchoscopy. Knowledge and understanding of tracheal bronchus is important for diagnosing symptomatic patients and performing certain procedures, including bronchoscopy and endotracheal intubation. Objective: The objective is to study the clinical profile, diagnosis, and management of tracheal bronchus detected during routine bronchoscopy in a tertiary care setting. Methods: This study was a retrospective analysis of hospital data of patients undergoing fiberoptic bronchoscopy for 2 years in a tertiary care setting. Results: There were 150 bronchoscopies performed during the period. A total of 42 anomalies were detected in 35 (23.33%) patients. Three patients had tracheal bronchus (2%). Conclusions: This retrospective study evaluated the presence of tracheal bronchus among patients who underwent bronchoscopy in a tertiary care hospital in Kerala, India. This study revealed that tracheal bronchus was present in 2% of all bronchoscopies done during that period.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127245174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liquid biopsy-detecting molecular targets in cancer management","authors":"N. Ravindran","doi":"10.4103/jalh.jalh_10_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_10_22","url":null,"abstract":"Liquid biopsies are newer diagnostic tests conducted on blood samples to detect biomarkers shed by tumors, such as cancer cells or portion of tumor DNA. Liquid biopsies are not to replace surgical biopsies but are complementary in the diagnosis and treatment of cancer. The circulating tumor DNA and intact circulating tumor cells are the two main components that are targeted during a liquid biopsy. Information from the liquid biopsy is used to determine the best-individualized cancer therapy to track how a patient is responding to treatment, or to discover whether there is recurrence of cancer. This review summarizes the main techniques and applications of liquid biopsy in cancer.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128837591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unexplained fever, weight loss, and worsened dyspnea with pulmonary hypertension as the presenting symptoms of mixed connective tissue disease with interstitial lung disease: A case report with review of literature","authors":"S. Patil, G. Gondhali, G. Narwade","doi":"10.4103/jalh.jalh_9_22","DOIUrl":"https://doi.org/10.4103/jalh.jalh_9_22","url":null,"abstract":"Pulmonary manifestations of mixed connective tissue disease (MCTD) include as bronchiolitis, bronchiectasis, and interstitial lung disease with or without pulmonary hypertension. Tuberculosis (TB) is the most common diagnosis in India in the presence of constitutional symptoms such as cough, fever, and weight loss with lung parenchymal abnormality, irrespective of microscopic or nucleic acid amplification test abnormalities due to high tuberculosis prevalent tropical setting. In this case report, a 35 year old female presented with constitutional symptoms and lung parenchymal nodules, interstitial involvement with lung fibrosis and pulmonary hypertension. Mediastinal window documented necrotic mediastinal lymph nodes, without negative mycobacterial microscopic (smear examination) or genome documentation (Gene Xpert MTB/RIF). She had received empirical anti tuberculosis treatment for three months without clinical or radiological response, resulted in progression of disease with clinical and radiological worsening and referred to our unit for further workup. Bronchoscopy guided evaluation for tropical screen including bacterial, fungal and tuberculosis with malignancy was inconclusive. Vasculitis and CTD workup documented antinuclear antibody (ANA) test strongly positive with very highly raised titres, with positive antigen as U1 small nuclear ribonucleoprotein particle, SSA/RO, single strand DNA, and Scl 70. Treatment initiated with systemic steroids, tadalafil, mycophenolate and diuretics, and satisfactory clinical response documented as near complete resolution of pulmonary parenchymal abnormalities in 24 weeks and pulmonary hypertension in 12 weeks. Pulmonary manifestations of MCTD are common, underestimated in the presence of constitutional symptoms, and early pickup of entity in course of illness will have good outcome with excellent prognosis.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121734432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronavirus disease 2019 and atrial fibrillation: A dreadful yet not uncommon association","authors":"Mansi Gupta, Nitesh Gupta, A. Mahendran, P. Ish","doi":"10.4103/jalh.jalh_21_21","DOIUrl":"https://doi.org/10.4103/jalh.jalh_21_21","url":null,"abstract":"","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117018356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of allergic rhinitis among students in the age group of 16-20 years in a South Indian City","authors":"Irfan Sheik, V. Moleyar","doi":"10.4103/jalh.jalh_8_21","DOIUrl":"https://doi.org/10.4103/jalh.jalh_8_21","url":null,"abstract":"Introduction: Allergic Rhinitis (AR) is often viewed as a trivial disease but it can significantly affect the quality of life by causing fatigue, headache, sleep disturbances, cognitive impairment. According to World Health Organization (WHO) report (2007), the global burden of allergic rhinitis was estimated to be 400 million, and the prevalence among adults ranges between 10% and 32% in the Asia Pacific region. The prevalence of allergic rhinitis and other allergic diseases has increased globally in the last three decades. Despite the high burden, there is a paucity of community-based studies in India, determining the burden of allergic rhinitis. Hence we undertook this study to determine the prevalence of allergic rhinitis among students (16-20 Years) of age. Materials and Methods: Students of age group 16-20 years of age, both Girls and boys in and around Mangaluru city, Dakshina Kannada district were included in the study. This was a questionnaire based cross sectional study. A standardized questionnaire (adopted from ISAAC) was prepared and was administered to students of 12 different colleges. The sample size was calculated after carefully analyzing previous Indian studies on the prevalence of allergic rhinitis. Considering an 8% prevalence rate and a 10% allowable error, sample size was estimated as N= 4600. Purposive sampling, among students of various colleges in Mangaluru city was done. The diagnosis of allergic rhinitis was done clinically as per ARIA guidelines. Students were interviewed in their class room for one hour. First the study objectives and the questionnaire was explained to the students. Then each student was given the questionnaire to fill. Informed consent was taken from each student. The statistical analysis was performed by Frequency and percentage method to calculate the prevalence. Chi-square test, odds ratio (OR), and 95% confidence interval (95%CI) were used to measure the association between the variables, and a p-value of <0.05 was considered to be significant. Results: In our study group, the age distribution was from 16-20 years. 961(20.8%) students were 16 years of age, 1196(26.0%) students were 17 years of age, 905(19.7) were 18years of age, 697(15.2%) 19 years of age & 841(18.3%) students were 20 years of age. The prevalence of allergic rhinitis among students (16-20) years of age was 11.9%. The prevalence was higher among girls (12.0%) compared to boys (11.7%). The prevalence of allergic rhinitis was more among students of 20 years of age. The prevalence of allergic rhinitis was more in girls (12.0%) compared to boys (11.7%). Smokers were found to be 2.6 times more prone to develop eczema. Statistically significant correlation between bronchial asthma with allergic rhinitis and eczema was found. Incidence of allergic rhinitis among asthma patients was 5.7times more compared to normal subjects. A significant association of asthma was observed with the incidence of eczema. Incidence of asthma among the peopl","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124586815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare tracheobronchial anomalies and their clinical significance","authors":"Charitha Puvvada, M. Nazim, M. Murali, R. Chetambath","doi":"10.4103/jalh.jalh_15_21","DOIUrl":"https://doi.org/10.4103/jalh.jalh_15_21","url":null,"abstract":"Tracheobronchial anomalies are often congenital and do not cause much symptoms to the individual. Majority of them are branching anomalies. Most of them are incidentally detected during bronchoscopy for unrelated diseases. However, rarely abnormal bronchi may present with symptoms. He we present two rare bronchial anomalies presenting with clinical symptoms attributed to them.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121392761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonexpanding pneumothorax despite double intercostal drainage tubes","authors":"A. Vijay, Aparna S. Nirmal, Melcy Cleetus, Jolsana Augustine, Rajesh Venkitakrishnan, D. Ramachandran","doi":"10.4103/jalh.jalh_13_21","DOIUrl":"https://doi.org/10.4103/jalh.jalh_13_21","url":null,"abstract":"Pneumothorax is one of the most common emergencies encountered in day-to-day pulmonary practice. Early diagnosis and prompt intervention will reduce morbidity as well as mortality. The mainstay of treatment involves tube thoracostomy and drainage of pneumothorax in all except the mild cases. Proper technique and ascertaining correct tube position with follow-up imaging ensure successful lung expansion. We share the case of a gentleman who presented with nonexpansion of lung despite inserting 2 intercostal drainage tubes for the management of pneumothorax. Imaging with computed tomography thorax revealed both tubes to be coiled within the chest wall without entry into pleural space, thereby accounting for failed reexpansion. This case stresses the importance of following a structured evaluation in cases of nonexpanding lung after tube thoracostomy for pneumothorax.","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130414112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and risk factors for allergic rhinitis","authors":"P. Mahesh","doi":"10.4103/jalh.jalh_24_21","DOIUrl":"https://doi.org/10.4103/jalh.jalh_24_21","url":null,"abstract":"","PeriodicalId":402083,"journal":{"name":"Journal of Advanced Lung Health","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124497693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}