Journal of Critical & Intensive Care最新文献

{"title":"The Neurobiological Basis of Post-Traumatic Stress Disorder","authors":"Bilal El‐Mansoury, Asmaa Haj-Khlifa, Jawad Laadraoui, Hanane El Fatimi, El Mehdi Dalil, Mohamed Hammani, Omar El Hiba, Samira Boulbaroud, Abdelali Bitar, Arumugam R. Jayakumar","doi":"10.4018/979-8-3693-2089-1.ch003","DOIUrl":"https://doi.org/10.4018/979-8-3693-2089-1.ch003","url":null,"abstract":"Post-traumatic stress disorder (PTSD) is a well-known mental health condition that affects millions of people worldwide. PTSD is characterized by a spectrum of psycho-emotional and neurophysiological effects, such as re-experiencing the trauma in the form of vivid intrusive memories, flashbacks, or nightmares. These experiences often are followed by overwhelming fear and strong physical sensations. Neuroimaging studies in patients with PTSD as well as experimental studies show alterations in brain areas such as the amygdala, hippocampus and prefrontal cortex as well as in neurochemical stress response systems. Additionally, it is believed that the main neurochemical features of PTSD include abnormal regulation of catecholamines, monoamines, and opioid neurotransmitters among others, each of which is found in brain circuits that regulate/integrate stress and fear responses. This chapter will provide an overview on the recent pathophysiological mechanisms underlying the development of PTSD.","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"1 1","pages":"55-100"},"PeriodicalIF":0.0,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147900993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tiny Tech, Big Impact","authors":"Kanwal Gul, Sunita Panicker, Swapnil Morandé, Veena Tewari","doi":"10.4018/979-8-3693-3230-6.ch023","DOIUrl":"https://doi.org/10.4018/979-8-3693-3230-6.ch023","url":null,"abstract":"Eating disorders and food waste present urgent public health and environmental crises requiring innovative solutions. Advances in artificial intelligence (AI) and mobile technology enable new interventions to promote healthy, sustainable eating habits. This research conceptualizes an AI system delivered via smartphone to monitor individuals' food contexts and deliver real-time nudges during preparation and consumption. Qualitative methodology through interviews and focus groups will refine nudge timing, content, and delivery for optimal impact based on user experiences. While human behavior remains complex, this research explores AI's potential to scale personalized interventions targeting problematic habits. Even minor improvements nudged at the individual level could have multiplicative benefits for population health and sustainability. Next steps include evaluating nudging effectiveness and addressing technical challenges like privacy and sustained engagement. Transdisciplinary collaboration is critical to develop ethical, human-centered AI systems for positive social change.","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"1 1","pages":"318-327"},"PeriodicalIF":0.0,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147911348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction to Neurodegenerative Diseases","authors":"Reihaneh Seyedebrahimi, Piao Yang, Maryam Azimzadeh, Mohsen Eslami Farsani, Shima Ababzadeh, Naser Kalhor, Mohsen Sheykhhasan","doi":"10.4018/979-8-3693-1281-0.ch002","DOIUrl":"https://doi.org/10.4018/979-8-3693-1281-0.ch002","url":null,"abstract":"Neurons are vital for brain function and communication. Neurodegeneration, the irreversible loss of neurons, disrupts brain-body interactions, causing diseases like Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), multiple sclerosis (MS), and Parkinson's disease (PD). Factors like aging, genetics, and environment contribute to these disorders. They affect various neurons, leading to speech, movement, sensory, and balance issues. Alzheimer's features amyloid plaques affecting memory. Parkinson's stems from midbrain dopaminergic neuron loss, causing tremors and mobility problems. Huntington's, a basal ganglia disorder, results from a gene mutation, inducing involuntary movements. MS involves neuron demyelination, causing diverse complications. ALS entails motor neuron degeneration, resulting in muscle weakness and paralysis. This chapter aims to provide a brief overview of neurodegenerative diseases and an introduction to some of its key characteristics.","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"1 1","pages":"25-58"},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147897250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Neural Networks for Early Diagnosis of Neurodegenerative Diseases","authors":"K. Suneetha, Karthik Kovuri, Chengamma Chitteti, J. Avanija, K. Reddy Madhavi, Naresh Tangadu","doi":"10.4018/979-8-3693-1281-0.ch006","DOIUrl":"https://doi.org/10.4018/979-8-3693-1281-0.ch006","url":null,"abstract":"Early diagnosis of neurodegenerative diseases plays a remarkable role in providing timely treatment for the affected person and reduces the mortality rate. Neurodegenerative diseases can affect the mental and physical health of a person and can impact decision-making. Deep neural networks help in automating disease diagnosis by identifying biomarkers from complex patterns of a large dataset. This chapter discusses the impact of using deep neural networks in neurodegenerative disease diagnosis. The initial section of the chapter focuses on the basics of neurodegenerative diseases and their impact on the well-being of the individual. The chapter also outlines the importance of transfer learning and multimodal fusion in early disease diagnosis. Finally, the chapter explores ethical considerations to be followed during the deployment of a deep learning model used in prediction of neurodegenerative disease. Thus, this chapter provides a remarkable role of deep learning architectures in neurodegenerative disease diagnosis.","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"1 1","pages":"112-127"},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147890201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental Animal Models of Sepsis and Septic Shock","authors":"Esin Ozcelebi, Alper Bektas Iskit","doi":"10.37678/dcybd.2023.3488","DOIUrl":"https://doi.org/10.37678/dcybd.2023.3488","url":null,"abstract":"","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134884801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Central Venous to- Arterial Carbon Dioxide Pressure Difference in Detection of Extubation Failure in Critically Ill Patients","authors":"Monika Verma, Madhulika Dubey, Mohd Mustahsin, Rajanikant Tripathi","doi":"10.37678/dcybd.2023.3416","DOIUrl":"https://doi.org/10.37678/dcybd.2023.3416","url":null,"abstract":"","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134884860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Purple Urine Bag Syndrome: A Bizarre Spot Diagnosis in ICU","authors":"Snehangsh Dash, Naveen Kumar","doi":"10.37678/dcybd.2023.3382","DOIUrl":"https://doi.org/10.37678/dcybd.2023.3382","url":null,"abstract":"","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136216926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alveolar Hemorrhage, Intracranial Bleeding, and Infective Endocarditis in A Young Case of Brucellosis","authors":"Hülya Mısır, N. Demir, Bahadır Benli","doi":"10.37678/dcybd.2023.3333","DOIUrl":"https://doi.org/10.37678/dcybd.2023.3333","url":null,"abstract":"","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69977155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional Citrate Anticoagulation: Basic Principles and Clinical Applications","authors":"Nazlihan Boyaci Dundar","doi":"10.37678/dcybd.2023.2324","DOIUrl":"https://doi.org/10.37678/dcybd.2023.2324","url":null,"abstract":"","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69976979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of High-Dose Vitamin C Therapy on Patients Diagnosed with COVID-19 Associated ARDS in Intensive Care Units: Multi-Center Retrospective Study","authors":"R. Yuksel, F. Yıldırım, C. Kıraklı, S. Temel, Seda Guzeldag, Z. Gullu, Esma Eryilmaz Eren, Meltem Şimşek, H. Sipahioğlu, Kamil İnci, G. Zararsiz, K. Gundogan, M. Sungur","doi":"10.37678/dcybd.2023.3215","DOIUrl":"https://doi.org/10.37678/dcybd.2023.3215","url":null,"abstract":"Background and Aim: The new type of Severe Acute Respiratory Syndrome Coronavirus 2 (Coronavirus 2019-COVID-19) infection is the largest pandemic in the last decade. Acute respiratory distress syndrome is the complication with the highest mortality rate of this infection and there is no adequate treatment with proven efficacy to reduce mortality. This multi-center, retrospective study aimed to determine the effect of high-dose vitamin C on survival and other endpoints in invasively ventilated ARDS patients. Method(s): This multi-center, observational retrospective cohort study was performed at five ICU centers between March 2020 and July 2020. Patients with ARDS due to COVID-19 who required IMV were included. High-dose vitamin C group was defined as patients who were treated with vitamin C over 200 mg/kg for four days. Patients who were not given vitamin C treatment were defined as the control group by using propensity score match analysis, as well. The groups were compared about the effects of high-dose vitamin C treatment on ICU mortality. Result(s): A total of 86 patients with a mean age of 67.85 +/- 10.38 were included in the study. 72.1% of the patients were male. Forty-two (49%) patients were in the high dose vitamin C group, and 44 (51%) were in the control group. The mean PaO2/FiO2 at the time of admission to the ICU was 128.27+/-58.69 mmHg (133.63+/-56.51 mmHg in the control group, 122.36+/-61.18 mmHg in the study group, p=0.389). The mortality rate of high dose vitamin C group was lower than the control group (73.8% vs. 90.9%, p = 0.037,respectively). Conclusion(s): As an adjunctive therapy in invasively ventilated patients with COVID-19-associated ARDS, high doses of vitamin C may reduce mortality and development of organ damage. Prospective, randomized controlled studies with larger numbers of patients are needed to confirm these findings.Copyright © 2023, Society of Turkish Intensivists. All rights reserved.","PeriodicalId":40137,"journal":{"name":"Journal of Critical & Intensive Care","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69977123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}