Malaysian Family Physician最新文献_第2页

Beyond graduation: The journey of a young family doctor in Malaysia. 毕业之后：马来西亚一位年轻家庭医生的旅程。

Malaysian Family Physician Pub Date : 2025-08-09 eCollection Date: 2025-01-01 DOI: 10.51866/mol.96y

Marina Antony Nicholson

引用次数: 0

Suspected liraglutide (glucagon-like peptide-1 receptor agonist)-induced hyperthyroidism: A case report. 疑似利拉鲁肽（胰高血糖素样肽-1受体激动剂）诱导的甲亢1例报告。

Malaysian Family Physician Pub Date : 2025-08-07 eCollection Date: 2025-01-01 DOI: 10.51866/cr.886

Siti Nur Syakinah Md Sabudin, Lili Husniati Yaacob, Muhammad Rahmat Che Omar

{"title":"Suspected liraglutide (glucagon-like peptide-1 receptor agonist)-induced hyperthyroidism: A case report.","authors":"Siti Nur Syakinah Md Sabudin, Lili Husniati Yaacob, Muhammad Rahmat Che Omar","doi":"10.51866/cr.886","DOIUrl":"10.51866/cr.886","url":null,"abstract":"Liraglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), is widely used for weight management and glycaemic control. While generally well-tolerated, various adverse effects have been reported. Thyroid dysfunction, particularly hyperthyroidism, is rare. This report describes the case of a 34-year-old woman with new-onset hyperthyroidism following liraglutide use for weight loss. The patient presented with worsening palpitations and insomnia after 3 weeks of liraglutide use. She had no prior thyroid disease or significant family history. Examination revealed sinus tachycardia with no goitre or tremors. Laboratory findings confirmed hyperthyroidism with a suppressed TSH level (0.03 mlU/L) and an elevated free T4 level (20.8 pmol/L). Thyrotropin receptor antibody was negative, ruling out Graves' disease. Liraglutide was discontinued, and the patient was treated with carbimazole and propranolol, resulting in symptom resolution and normalisation of thyroid function within weeks. Liraglutide-induced thyroid dysfunction is poorly understood. Possible mechanisms include GLP-1 receptor activity in thyroid tissue, disruption of the hypothalamic-pituitary-thyroid axis or inflammation of thyroid follicular cells. This case demonstrates a strong temporal association between liraglutide use and hyperthyroidism, which resolved upon drug discontinuation. Although thyroid dysfunction with GLP-1 RAs has been noted in preclinical studies, human data remain limited. This case highlights a rare adverse effect of liraglutide and underscores the need for vigilance when monitoring patients on GLP-1 RAs. Monitoring of thyroid function should be considered in symptomatic patients. Further research is warranted to better understand the underlying mechanisms and prevalence of GLP-1 RA-induced thyroid abnormalities.","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"58"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lymphoedema - Filariasis or soft tissue sarcoma? A case report. 淋巴水肿-丝虫病还是软组织肉瘤？一份病例报告。

Malaysian Family Physician Pub Date : 2025-07-29 eCollection Date: 2025-01-01 DOI: 10.51866/cr.877

Tamring Sarinah, Mat Nawi Zanaridah, Nik Yusof Fuad Nik Farah, Joon Hi Tham, Mohamad Setia Awang Shahrunizam

引用次数: 0

Prevalence and associated factors of female sexual dysfunction among primary care practitioners in Malaysia: A cross-sectional study. 马来西亚初级保健从业者中女性性功能障碍的患病率和相关因素：一项横断面研究。

Malaysian Family Physician Pub Date : 2025-07-29 eCollection Date: 2025-01-01 DOI: 10.51866/oa.883

Rosli Salwa, Abd Halim Haizlene, Md Yasin Mazapuspavina, Leny Suzana Suddin

{"title":"Prevalence and associated factors of female sexual dysfunction among primary care practitioners in Malaysia: A cross-sectional study.","authors":"Rosli Salwa, Abd Halim Haizlene, Md Yasin Mazapuspavina, Leny Suzana Suddin","doi":"10.51866/oa.883","DOIUrl":"10.51866/oa.883","url":null,"abstract":"Introduction: Sexual health is integral to quality of life, and female sexual dysfunction (FSD) is a significant public health concern recognised by the World Health Organization. Its prevalence is rising globally, with limited data among primary care practitioners (PCPs). Multifactorial issues such as high work burden in PCPs, coupled with low help-seeking behaviours, contribute to the likelihood of FSD and poor quality of life. This study aimed to determine the prevalence and associated factors of FSD among PCPs in Malaysia.Methods: This cross-sectional study was conducted using a self-administered online questionnaire for 6 months duration in Malaysia. Sociodemographic, marital and clinical data were collected, and two validated questionnaires namely the Malay Version of the Female Sexual Function Index (MVFSFI) and the Depression, Anxiety and Stress Scale (DASS-21) were utilised. Data analysis included descriptive statistics and logistic regression.Results: The study included 382 participants. The prevalence of FSD was 14.7% (95% confidence interval [CI] : 11.1, 18.2) among the participants, and the most affected domain was desire disorder (25.4%). Significant associations were observed between sexual activity two or fewer times per month (adjusted odds ratio [aOR]: 4.880; 95% CI: 2.522, 9.442; P<0.001), depression (aOR: 3.450; 95% CI: 1.653, 7.204; P<0.001) and degree-level education (aOR: 2.659; 95% CI: 1.338, 5.285; P=0.005) and FSD.Conclusion: This study identifies FSD as a prevalent issue among Malaysian PCPs, emphasising its biopsychosocial complex and the need for a holistic approach. Understanding the cultural determinants of FSD is important to tailor screening and intervention strategies.","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Practice Guidelines on the Management of Menopause in Malaysia 2022: A review from a primary care perspective. 马来西亚2022年更年期管理临床实践指南：从初级保健角度回顾。

Malaysian Family Physician Pub Date : 2025-07-22 eCollection Date: 2025-01-01 DOI: 10.51866/cpg.910

Wai Khew Lee, Noreen Zhi Min Ooi, Soo Lee Goh

{"title":"Clinical Practice Guidelines on the Management of Menopause in Malaysia 2022: A review from a primary care perspective.","authors":"Wai Khew Lee, Noreen Zhi Min Ooi, Soo Lee Goh","doi":"10.51866/cpg.910","DOIUrl":"10.51866/cpg.910","url":null,"abstract":"Introduction: Clinical practice guidelines (CPGs) are important tools that assist primary care doctors in their daily practice. Menopause is a physiological condition that affects all women, and the latest Malaysian CPG on menopause can provide guidance on the optimal management of women facing this condition. However, not all CPGs are of acceptable quality, and it is important that primary care doctors learn to critically appraise CPGs to ensure their practice is evidence-based and relevant to their patients. This review aimed to critically appraise the Clinical Practice Guidelines on the Management of Menopause in Malaysia 2022 to ensure that it is valid and applicable to primary care in Malaysia.Methods: Three family medicine specialists independently appraised the CPG using the AGREE II Instrument, which consists of six domains assessing the following: (1) scope and purpose, (2) stakeholder involvement, (3) rigour of development, (4) clarity and presentation, (5) applicability and (6) editorial independence. They also provided an overall assessment of quality and recommendation on the use of the CPG following the AGREE II guideline.Results: The CPG scored >70%, which is the threshold of quality in all domains except for applicability. The reviewers deemed the CPG to be of high quality and recommended its adoption without any modifications.Discussion: It is important to ensure that recommendations in a CPG are evidence-based and valid before they are adopted into practice. The AGREE II Instrument can assist primary care doctors in critically appraising CPGs.","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"50"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A cautionary tale of hyponatraemia in an older person: Could This Have Been Prevented? 一个老年人低钠血症的警示故事：这是可以预防的吗？

Malaysian Family Physician Pub Date : 2025-07-22 eCollection Date: 2025-01-01 DOI: 10.51866/tyk.502

Yi Bin Ho, Rebecca Kai Jan Choong, Kit Mun Tan

引用次数: 0

Transformation of medical libraries: Reflections from a 20-year journey. 医学图书馆的转型：20年历程的思考。

Malaysian Family Physician Pub Date : 2025-07-14 eCollection Date: 2025-01-01 DOI: 10.51866/mol.947

Apichai Wattanapisit

引用次数: 0

A dark umbilical nodule in a postmenopausal woman: What is your diagnosis? 绝经后妇女脐暗结节：你的诊断是什么？

Malaysian Family Physician Pub Date : 2025-07-14 eCollection Date: 2025-01-01 DOI: 10.51866/tyk.453

Nur Hidayah Mohd Fauzi, Nik Ahmad Zuky Nik Lah, Siti Masitah Hamzah, W Fadhlina W Adnan, Adibah Ibrahim, Noorul Balqis Che Ibrahim, Engku Ismail Engku-Husna

引用次数: 0

Garlic burns are not burns. 大蒜烧伤不是烧伤。

Malaysian Family Physician Pub Date : 2025-07-14 eCollection Date: 2025-01-01 DOI: 10.51866/lte.955

Jazlan Jamaluddin, Siti Nuradliah Jamil, Siti Khamsiah Abd Shukor

引用次数: 0

Development of chronic subdural haematoma from mild head injury: A case report and review of current Malaysian guidelines on traumatic brain injury. 轻度头部损伤引起的慢性硬膜下血肿的发展：一个病例报告和对目前马来西亚创伤性脑损伤指南的回顾。

Malaysian Family Physician Pub Date : 2025-07-12 eCollection Date: 2025-01-01 DOI: 10.51866/cr.776

Qingping Joseph Feng, Ian James Long, Su Lone Lim, Ira Siyang Sun, Shiong Wen Low, Chun Peng Goh

{"title":"Development of chronic subdural haematoma from mild head injury: A case report and review of current Malaysian guidelines on traumatic brain injury.","authors":"Qingping Joseph Feng, Ian James Long, Su Lone Lim, Ira Siyang Sun, Shiong Wen Low, Chun Peng Goh","doi":"10.51866/cr.776","DOIUrl":"10.51866/cr.776","url":null,"abstract":"Delayed chronic subdural haematoma (cSDH) is a common but potentially serious complication following traumatic brain injury (TBI). Mild TBIs are commonly managed by primary care providers (PCPs), particularly in large, resource-limited settings such as Malaysia, where access to tertiary neurosurgical services may be delayed. Early identification of red-flag signs and symptoms and timely referrals are crucial to prevent clinical deterioration. We describe the case of a 66-year-old man who sustained mild head injury following a vasovagal syncope. His initial brain CT revealed evidence of a small traumatic subarachnoid haemorrhage over the left precentral sulcus, with resolution on an interval scan 24 hours later. He was discharged home without follow-up. Eleven weeks later, he developed bilateral lower-limb weakness and unsteady gait, which prompted an urgent referral by his general practitioner. Repeat CT revealed bilateral acute-on-chronic subdural haematomas, with mass effect requiring emergency burr-hole drainage. The patient showed excellent post-operative improvement and was discharged home on day 4, with no clinical or radiological recurrence on subsequent follow-up. This case highlights the risk of delayed cSDH in patients following mild TBI, even in those discharged with a normal CT scan. PCPs play a pivotal role in recognising high-risk patients, ensuring structured follow-up and facilitating timely specialist referral. We advocate for updating the Malaysian head injury guidelines to incorporate routine follow-up protocols for at-risk patients, modelled after international standards.","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"45"},"PeriodicalIF":0.0,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0