Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society最新文献

{"title":"Immunohistochemical expression of histone modification pattern in adult glioblastoma.","authors":"B Archana, Lawrence D'Cruze, Sandhya Sundaram, Krishnakumar Ramanathan, Krishnamurthy Ganesh","doi":"10.4103/jcrt.jcrt_257_22","DOIUrl":"10.4103/jcrt.jcrt_257_22","url":null,"abstract":"<p><strong>Background: </strong>Despite the growing advances in molecular research and therapeutics, glioblastomas are still considered highly invasive aggressive tumors with a median survival of 15 months. Genetic alterations have been studied in detail; however, additionally, there is now growing evidence on the role of epigenetic alterations in glioblastoma. Recently, histone modification patterns have been found to have a significant part in gene expression and prognosis. However, further research in this field is warranted to establish its role for the betterment of these patients with the deadly disease.</p><p><strong>Aims: </strong>To determine the immunohistochemical expression of histone modifications like histone-3-lysine-18 acetylation (H3K18Ac) and histone-4-lysine 20 trimethylation (H4K20triMe) in glioblastoma patients.</p><p><strong>Materials and methods: </strong>This is a retrospective study of 48 glioblastoma patients who underwent surgery. Immunohistochemistry (IHC) for tri-methyl-histone-H4 (Lys20) (H4K20triMe) and acetyl-histone-H3 (Lys18) (H3K18Ac) was performed in paraffin-embedded tissues manually, and the expression was noted. Data on the mitotic index and overall survival was collected and statistically analyzed.</p><p><strong>Results: </strong>The mean age was 50 years with a M: F ratio of 1.6:1. Out of 48 cases, 60% (28 cases) demonstrated positivity for H3K18Ac and 98% (46 cases) for H4K20triMe. The pattern of expression was nuclear with increased expression adjacent to necrosis and at the invasive front. The overall median Q score for H3K18Ac was 1/12 and for H4K20triMe was 6/12. No significant statistical significance was observed between histone expression, Ki67%, and overall survival.</p><p><strong>Conclusion: </strong>Histone modification patterns are being explored in detail in an array of tumors. They also have a potential role in glioblastoma for risk stratification and instituting appropriate treatment based on the prognosis. Epigenetic changes like histone modification patterns, in addition to genetics, can pave the way for a better molecular understanding of glioblastomas and provide hope in the future to improve the survival of these patients with deadly diseases.</p>","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":"18 1","pages":"52-56"},"PeriodicalIF":1.3,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90694445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short time Resistance Spot Welding of 1.2GPa Ultra-High Strength Steel using High Frequency Power Supply","authors":"Yohsuke Abe, N. Yoshioka, Yoshihito Kinoshita, S. Yamane","doi":"10.2207/qjjws.41.178","DOIUrl":"https://doi.org/10.2207/qjjws.41.178","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68000906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The lymph node in IgA vasculitis (Henöch-Schonlein purpura).","authors":"Samuel M Law, Jeffrey J Fadrowski, Ivo M B Francischetti","doi":"10.1007/s12308-023-00546-7","DOIUrl":"10.1007/s12308-023-00546-7","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":"15 1","pages":"185-186"},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90686653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening of Al/Cu dissimilar joint due to complicated interface produced by pulsed TIG welding with a constricted nozzle","authors":"Hajime Yamamoto, Yusuke Yanagi, Kazuhiro Ito, Hisaya Komen, Manabu Tanaka, A. Murata","doi":"10.2207/qjjws.41.168","DOIUrl":"https://doi.org/10.2207/qjjws.41.168","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45448920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct bonding of Ni nanoparticles to a semiconductor Al electrode in air and its form","authors":"Yasunori Tanaka, K. Koshiba, T. Iizuka, Mayumi Ito, K. Higashimine, K. Tatsumi","doi":"10.2207/qjjws.41.159","DOIUrl":"https://doi.org/10.2207/qjjws.41.159","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45801608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microstructure of the interface between Aluminum Alloy and Galvannealed Steel Plates Jointed by FSSW Multi-Step Loading Process","authors":"Iori Kojima, C. Iwamoto, Yuka Shimizu, T. Matsuda, A. Hirose","doi":"10.2207/qjjws.41.90","DOIUrl":"https://doi.org/10.2207/qjjws.41.90","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45682444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Solidification Cracking Susceptibility Factors in Carbon Steel and Availability of Ti Addition Based on Theoretical Analysis","authors":"N. Sahara, Shotaro Yamashita, K. Ono, K. Saida","doi":"10.2207/qjjws.41.150","DOIUrl":"https://doi.org/10.2207/qjjws.41.150","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43335011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-speed Hot-wire laser Brazing Technology for Steel/Aluminum alloy Dissimilar Joint using Twin Beam Irradiation","authors":"Tamaki Ito, CHOI Jeong-Won, Motomichi Yamamoto, K. Taniguchi, Y. Okita, H. Matsuda","doi":"10.2207/qjjws.41.116","DOIUrl":"https://doi.org/10.2207/qjjws.41.116","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47290604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Annealing on the Interfacial Microstructure and Mechanical Properties of Explosively Welded AZ80 Magnesium Alloy and A6005C Aluminum Alloy","authors":"Mami Mihara-Narita, Konosuke Asai, H. Mori, N. Saito, Y. Chino, H. Sato, Yoshimi Watanabe","doi":"10.2207/qjjws.41.107","DOIUrl":"https://doi.org/10.2207/qjjws.41.107","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42580323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Plate Deformation Around the Nugget during Tensile Test on Tensile Shear Strength of Resistance Spot Welded Lap Joints","authors":"T. Kitamura, T. Akiyama, Mitsuhiro Imamura, T. Kawabata, Atsuro Uemura, C. Mihara, Koki Iwatani","doi":"10.2207/qjjws.41.11","DOIUrl":"https://doi.org/10.2207/qjjws.41.11","url":null,"abstract":"","PeriodicalId":39980,"journal":{"name":"Yosetsu Gakkai Ronbunshu/Quarterly Journal of the Japan Welding Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43840983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}