Journal of Medicine, University of Santo Tomas最新文献

{"title":"The C.O.P.E. Typology of Coping with Stressors at Sea among Filipino Merchant Marine Ratings: A Q Methodology Study","authors":"Clarissa M Mendoza, Maria Minerva P. Calimag, Susannah O Salvador","doi":"10.35460/2546-1621.2021-0156","DOIUrl":"https://doi.org/10.35460/2546-1621.2021-0156","url":null,"abstract":"Background: The seafarers’ poor mental health has been associated with significant morbidity, inefficiency, and accidents on board. Mental and physical health is largely dependent on the way seafarers handle stressors. Anchored on the Transactional Model of Stress and Coping, this study aimed to identify the typology of Filipino merchant marine ratings according to their coping strategies to stressors on board vessels. Methods: Thirty-seven (37) Filipino merchant marine ratings participated in this study. They were chosen by purposive sampling. They rank-ordered 25 opinion statements on various stressors and coping mechanisms. The rank-ordered sorts were subjected to by-person factor analysis with Varimax rotation using the PQ Method version 2.32. The resulting factors were interpreted using the inductive approach, aided by the interview done after Q sorting. Results: Four factors were generated: solution-focused seafarers, stressor-focused seafarers, self-management–focused seafarers, and the social milieu-focused seafarers. There is a consensus on the supplication-focused seafarers who ask for God’s help in times of stress. Conclusion: The generated typology provides a better understanding of seafarers’ outlook on stress and coping and may help the stakeholders craft individualized strategies to help improve their coping mechanisms and overall mental health. Occupational health research must continue to focus on understanding the role of culture and adaptation on stress and coping behaviors to retain quality seafarers and promote a healthier workplace.","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125546935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physician-Scientist, Academician and Published Research Author","authors":"R. Rosales","doi":"10.35460/2546-1621.2021-0162","DOIUrl":"https://doi.org/10.35460/2546-1621.2021-0162","url":null,"abstract":"Based largely on interest and preference, there are physician-scientists who are engaged in the dual work of being a clinician and researcher. Some of them have the added responsibility of also being academicians or members of medical faculties. The article, “Physician as a Clinician, Researcher and Academician” in this JMUST issue demonstrates the importance of organizational support and collaboration for physicians. The doctor has multiple roles to navigate through three settings: clinics, research centers, and classrooms to fulfill the mission of better public health. Research and dissemination of findings through publication are almost sine qua non when the physician blends the roles of clinician, researcher, and academician. Within the purview of translational research, the clinician is informed and applies the knowledge base for better patient care.","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"Volume 21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124430908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 15-Year Review of Ocular Manifestations of Autoimmune Inflammatory Disorders in a University Hospital","authors":"Gerald B Natanauan, J. Li-Yu, Jessica C Daza-Robes, J. M. Abaño","doi":"10.35460/2546-1621.2020-0083","DOIUrl":"https://doi.org/10.35460/2546-1621.2020-0083","url":null,"abstract":"Background: Autoimmune diseases represent a significant health burden for 3% to 9% of the general population, and rheumatology, perhaps more than any other medical subspecialty, encompasses a broad array of such diseases that affect a wide range of organ systems including the eye. It serves as a sensitive barometer of autoimmune phenomena in many of the rheumatic diseases. Objective: The study determined the various ocular manifestations of all autoimmune inflammatory disorders at the University of Santo Tomas Hospital, Section of Rheumatology and the Department of Ophthalmology from 2003 to 2018. Methodology: A retrospective cohort study was done involving chart review of patients from both private division and clinical division. Sex, age, duration of disease, medications given, and ocular manifestations were determined. Statistical analysis included frequencies, percentages, and logistic regression analysis. Results: Sixty-seven patients were included in the study. Of these, 58.2% (39/67) had ocular manifestations secondary to an established autoimmune disease. It was found out that 58.97% (23/39) had Vogt-Koyanagi-Harada syndrome. Other autoimmune diseases with ophthalmologic manifestations were systemic lupus erythematosus at 12.8% (5/39), ankylosing spondylitis at 10.25% (4/39), rheumatoid arthritis and Behcet’s syndrome at 5.12% (2/39), and granulomatosis with polyangiitis, scleroderma and psoriatic arthritis at 2.56% (1/39). Conclusion: In this population, the frequency of ocular manifestations of autoimmune diseases remained low with anterior uveitis as the most common. Close coordination between specialties is very important in the course of treatment and management to lessen its complications and related morbidity.","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"213 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131944382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of Sleep-Related Breathing Disorders Among Pediatric Patients with Allergic Rhinitis: A Cross-Sectional Study in a University Hospital","authors":"J. O. C. Go, Olivia C. Go, C. Rivera","doi":"10.35460/2546-1621.2020-0017","DOIUrl":"https://doi.org/10.35460/2546-1621.2020-0017","url":null,"abstract":"Introduction: Allergic rhinitis is a common condition in children linked to sleep-related breathing disorders (SRBD). Because of nasal congestion, it can cause obstructive sleep apnea, sleep fragmentation, and excessive fatigue. Studies regarding its association with SRBD is limited. Objectives: To determine the association of allergic rhinitis with sleep-related breathing disorders. Methodology: A cross-sectional analytical study involving pediatric patients diagnosed with allergic rhinitis was conducted. Allergic rhinitis severity was evaluated with the ARIA classification. SRBD was identified using the validated Filipino version of the pediatric sleep questionnaire. Potential association between allergic rhinitis and SRBD were assessed using the student’s t-test, Fisher’s exact test and odds ratio. Results: A total of 66 children with mean age 8.2 years were included in the study. The mean age, weight, height, and BMI were comparable among participants who were positive or negative for obstructive sleep apnea (OSA). Among the perceived problems related to sleeping disorders, snoring loudly, heavy breathing, dry mouth of awakening, not listening, and difficulty organizing showed different responses (p<0.05) among the subgroups of allergic rhinitis. The odds ratio of snoring loudly, not listening, difficulty organizing, heavy breathing, and unfreshened in the morning were more likely among patients with mild persistent allergic rhinitis compared to patients with mild intermittent allergic rhinitis. Conclusion: There was sufficient evidence to prove the association of SRBD with severity of allergic rhinitis using the validated Filipino version of the Pediatric Sleep Questionnaire. OSA shows a greater likelihood among patients with mild persistent allergic rhinitis compared to those with mild intermittent allergic rhinitis.","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122094512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“STOP the PUFF! Tayo’y mag bagong BAGA, SIGARILYO ay ITIGIL”: A Pilot Community-based Tobacco Intervention Project in an Urban Settlement","authors":"Irene Salve D Joson-Vergara, J. Li-Yu","doi":"10.35460/2546-1621.2020-0040","DOIUrl":"https://doi.org/10.35460/2546-1621.2020-0040","url":null,"abstract":"The success rate for smoking cessation in the country remain low despite the intensified efforts of the government to curb smoking. There is a need to support tobacco control policies with clinical interventions for smoking cessation. However, cessation experts in the country are few and healthcare workers with training on tobacco interventions are limited.  The project aimed to address the clinical aspect of tobacco control by establishing tobacco cessation services in the community. This was done by providing brief tobacco intervention training among health workers and community leaders, thus allowing this intervention to be integrated in the existing programs of the community health center. This also led to the creation of possible referral mechanisms to cessation support providers. This was complemented with health education activities that promote smoke-free behavior. Keywords: tobacco; cigarette smoking; tobacco dependence; smoking cessation; brief advice; brief tobacco intervention​​​​​","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127518868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profile and Treatment Outcomes of Filipino Multiple Myeloma Patients Managed at a Tertiary Institution: A Single Center Six-Year Retrospective Study","authors":"Joybell Castro, F. Mesina, P. Caguioa","doi":"10.35460/2546-1621.2019-0025","DOIUrl":"https://doi.org/10.35460/2546-1621.2019-0025","url":null,"abstract":"Introduction: Multiple myeloma remains to be an incurable hematologic entity, but with the advent of novel agents more patients experience significantly longer survival. In a third world country like the Philippines, autologous bone marrow transplant after chemotherapy for newly diagnosed cases which is the standard of care is difficult to comply. The management paradigm for myeloma has shifted over the years, hence this study. Objective: Determine the clinical profile and treatment outcome of Filipino multiple myeloma patients diagnosed and managed at a tertiary institution from January 2013 to December 2018. Methodology: Retrospective, observational and cross-sectional study of eligible symptomatic myeloma patients. Results: Data for six years were retrospectively collected from a single tertiary institution. The clinical characteristics at diagnosis, treatment and survival rates of 109 active myeloma patients were described. The median age was 61 years (range, 28–83), with 51.4% being female. Median overall survival was 49.5 months (95% CI 42.7–56.2). The frontline treatments of patients were also analyzed. The combined deep response (complete and very good partial) of our patients at 31.7% was higher than of Asian Myeloma Network Study at 30.9%. None of them yet underwent autologous bone marrow transplantation as of date. Novel agents, especially bortezomib was used in 35.7% and significantly affected overall and progression-free survivals when used as a first line treatment. Conclusion: This retrospective analysis demonstrated the paradigm shift in the treatment modality of myeloma and the survival outcomes has significantly improved, especially on the best response to chemotherapy. Short of the ideal management in a third world country like the Philippines, we can now set our new standard of care based on the treatments available including novel agents like bortezomib, and the best practices that our institution offers. Keywords: Multiple Myeloma, Profile, Outcomes, Tertiary","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130743991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"JMUST Tribute to Sesquicentennial of UST - Faculty of Medicine and Surgery","authors":"Raymond Rosales","doi":"10.35460/2546-1621.2021-0090","DOIUrl":"https://doi.org/10.35460/2546-1621.2021-0090","url":null,"abstract":"","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117078429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Locally Advanced Papillary Thyroid Carcinoma in a Thyroglossal Duct Cyst Presenting as a Benign Cervical Mass: A Case Report","authors":"Ace Joseph C de la Rosa, M. K. A. Capuz","doi":"10.35460/2546-1621.2018-0077","DOIUrl":"https://doi.org/10.35460/2546-1621.2018-0077","url":null,"abstract":"Thyroglossal duct cyst is the most commonly encountered midline and upper cervical mass that can also be a rare form of malignancy of about <1%. This is a rare case without well-defined management and staging criteria and as such, it has been a cause of debates regarding optimal management as well as the extent of completeness of surgery from Sistrunk procedure only to Sistrunk procedure with total thyroidectomy. Conclusion: This is a case report of a rare occurrence of a locally advanced papillary thyroid carcinoma of thyroglossal duct cyst presenting as a benign cervical mass. The management dilemma and ultimate surgical approach was carefully drawn with the patient.","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131468822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Betwixt and Between: Exploring the Liminal Space of the ‘First Generation’ Filipino Physician Through the Lens of the Rites of Passage","authors":"L. Garcia, Maria Minerva P. Calimag, Alejandro C. Baroque II, Ma. Lourdes P Corrales-Joson","doi":"10.35460/2546-1621.2020-0030","DOIUrl":"https://doi.org/10.35460/2546-1621.2020-0030","url":null,"abstract":"Introduction: The ‘first generation’ physician gathers a lot of strength to venture into a world unknown to him. Unlike a physician born to a family of physicians who has a family to guide him, the ‘first generation’ physician only has himself to survive this endeavor. Through the life worlds of a select group of ‘first generation’ physician-in-training, this study seeks to answer the following central question: How do ‘first generation’ Filipino physicians collectively characterize their liminal spaces in transition from medical school to clinical practice? Methodology: Anchored on the Theory of the Rites of Passage, this phenomenological inquiry, intends to surface the lebenswelt or essence of the experience of being the only physician in the family. Respondents comprised a purposive sample of physicians-in-training (residents and fellows), who are the only physicians in the family. Data were gathered using semi-structured interviews. Triangulation and member checking procedures were done to ensure the data reliability. Data were then subjected to cool (categorization) and warm analysis (thematization) using the Colaizzi's method. Findings and Discussion: With all the transcribed experiences summarized and those with the same meaning analyzed, the following categories and themes were generated: The Intending Facet / Purpose: From Uncertainty towards Redefinition; The Thinking Facet / Process: From Perplexity towards Self-efficacy; The Relating Facet / People: From Isolation towards Integration; and The Transforming Facet / Power: From Vulnerability towards Empowerment. It was shown that a ‘first generation’ physician in this liminal space undergoes challenges and struggles during his training in medicine. This served as his Rite of Passage to transition him to someone dreaming only to become a physician, to become redefined with conviction, supported and integrated into the health system, empowered and transformed to the physician he is meant to be. Recommendations: Physicians undergo a lot of challenges and mental stress and it means a lot for trainers to enter into the trainees’ life-world, especially that of a ‘first generation’ physician, so that they can build socio-emotional learning and mentoring programs and counselling services that address different facets of liminal space that the trainees go through.","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134567967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemotherapy-Induced Leukoencephalopathy: A Case Series","authors":"P. B. E. Nuqui, Flerida G Hernandez","doi":"10.35460/2546-1621.2019-0057","DOIUrl":"https://doi.org/10.35460/2546-1621.2019-0057","url":null,"abstract":"Rationale: Leukoencephalopathy, a complication associated with chemotherapy has been reported after giving high doses of methotrexate and cytarabine with no specific risk factors to date.  Objectives: To review the prevalence of chemotherapy-induced leukoencephalopathy in children with acute lymphoblastic leukemia (ALL). To present the clinical course, pathogenesis and neuro-imaging findings of chemotherapy-induced leukoencephalopathy in children with ALL. Case: We reported three cases of adolescent ALL precursor B-cell patients who received high doses of methotrexate and presented with neurologic and MRI findings consistent with leukoencephalopathy. Our patients were only placed on supportive measures with adequate hydration, without providing any special intervention. Yet, all of them had complete neurological recovery.  Discussion and Summary: Methotrexate is a cell cycle-specific agent that inhibits the enzyme dihydrofolate reductase, preventing the conversion of folic acid to tetrahydrofolic acid and inhibiting cell replication. It is one of the most commonly implicated drug causing leukoencephalopathy.[3] On MRI T2-weighted images, all of them had hyperintensities on the posterior frontal/parietal corona radiata and centrum semiovale consistent with leukoencephalopathy. Complete recovery happened spontaneously in all of the cases. There is no standard treatment for acute and subacute toxicities from methotrexate.  Keywords: Leukoencephalopathy, Chemotherapeutic drugs, Neurotoxicity, Case series","PeriodicalId":399180,"journal":{"name":"Journal of Medicine, University of Santo Tomas","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133310001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}