Clinical DiabetesPub Date : 2025-09-26eCollection Date: 2025-05-01DOI: 10.2337/cd25-0056
Kimberly Yuang, Anna L Espinoza, Rozalina G McCoy
{"title":"Glycemic Management in Adults With Diabetes During Illness.","authors":"Kimberly Yuang, Anna L Espinoza, Rozalina G McCoy","doi":"10.2337/cd25-0056","DOIUrl":"10.2337/cd25-0056","url":null,"abstract":"<p><p>Optimal management of hyperglycemia during illness has been hindered by a lack of comprehensive sick-day guidance, particularly for adults with diabetes. Managing glycemia can be challenging during illness because of adaptive counterregulatory hormonal changes, acute stress of illness, altered dietary intake, and effects of medications. People with diabetes may be at risk for severe hypoglycemia and hyperglycemic crisis during illness unless mitigated by close monitoring and medication adjustment. This article provides practical guidance to health care professionals and people with diabetes for safe glycemic management during illness, including considerations for insulin and noninsulin medications, use of insulin technologies, prevention of hypoglycemia and ketoacidosis, steroid use, and pregnancy.</p>","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 5","pages":"735-745"},"PeriodicalIF":0.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical DiabetesPub Date : 2025-09-25eCollection Date: 2025-05-01DOI: 10.2337/cd25-0053
Selorm Dei-Tutu, Fulfilled Ighalo, Pavandeep Rakhra, Rebecca Butler, Amelia Martinez, Kelly Timmons, Don Buckingham, David D Schwartz, Meghan Craven
{"title":"Reducing Diabetic Ketoacidosis Incidence in Children With Type 1 Diabetes Through Wraparound Services at Texas Children's Hospital: The REACH Program.","authors":"Selorm Dei-Tutu, Fulfilled Ighalo, Pavandeep Rakhra, Rebecca Butler, Amelia Martinez, Kelly Timmons, Don Buckingham, David D Schwartz, Meghan Craven","doi":"10.2337/cd25-0053","DOIUrl":"10.2337/cd25-0053","url":null,"abstract":"<p><p>Quality Improvement Success Stories are published by the American Diabetes Association in collaboration with the American College of Physicians and the National Diabetes Education Program. This series is intended to highlight best practices and strategies from programs and clinics that have successfully improved the quality of care for people with diabetes or related conditions. Each article in the series is reviewed and follows a standard format developed by the editors of <i>Clinical Diabetes</i>. The following article describes an initiative to reduce the incidence of diabetic ketoacidosis in children with type 1 diabetes at high risk for complications.</p>","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 5","pages":"847-852"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical DiabetesPub Date : 2025-09-25eCollection Date: 2025-05-01DOI: 10.2337/cd25-0068
Ashley S Lin, William B Horton, Marc D Breton, Meaghan M Stumpf
{"title":"Capillary Ketone Monitoring-Guided Adaptation of Automated Insulin Delivery to Accommodate a Ketogenic Diet in an Individual With Type 1 Diabetes: Case Study and Literature Review.","authors":"Ashley S Lin, William B Horton, Marc D Breton, Meaghan M Stumpf","doi":"10.2337/cd25-0068","DOIUrl":"10.2337/cd25-0068","url":null,"abstract":"","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 5","pages":"858-860"},"PeriodicalIF":0.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical DiabetesPub Date : 2025-09-19eCollection Date: 2025-05-01DOI: 10.2337/cd25-0019
Anthony S Walls, Nathan J Carroll
{"title":"Association of Hypoglycemia With the Time to Dextrose in Treatment of Diabetes-Related Ketoacidosis.","authors":"Anthony S Walls, Nathan J Carroll","doi":"10.2337/cd25-0019","DOIUrl":"10.2337/cd25-0019","url":null,"abstract":"<p><p>Guidelines for the treatment of diabetes-related ketoacidosis (DKA) recommend adding i.v. dextrose or enteral glucose when a patient's blood glucose level has decreased sufficiently to help prevent hypoglycemia. This study sought to determine whether a delay in this intervention was associated with a higher incidence of hypoglycemia. It found that patients are at increased risk for hypoglycemia during the active treatment window of DKA, as well as during the entire hospitalization, when the addition of dextrose or glucose is delayed.</p>","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 5","pages":"696-702"},"PeriodicalIF":0.0,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical DiabetesPub Date : 2025-09-08eCollection Date: 2025-05-01DOI: 10.2337/cd25-0051
Marianne Chebli, Silva Arslanian, Kim Hoyek, Caleb Harrison, Ingrid Libman, Xu Qin, Mary Ellen Vajravelu
{"title":"Child Opportunity Index: Does It Foretell Future Glycemic Control and Health Care Utilization in Youth With Type 1 or Type 2 Diabetes?","authors":"Marianne Chebli, Silva Arslanian, Kim Hoyek, Caleb Harrison, Ingrid Libman, Xu Qin, Mary Ellen Vajravelu","doi":"10.2337/cd25-0051","DOIUrl":"10.2337/cd25-0051","url":null,"abstract":"<p><p>This article reports on a retrospective study examining associations between neighborhood opportunity and glycemic trajectory and health care utilization among youth with diabetes using current Child Opportunity Index (COI) data linked to ZIP codes. The study found that glycemic control and health care utilization were worse in the setting of adverse COI and individual social determinants of health, but both were also independently associated with race.</p>","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 5","pages":"660-669"},"PeriodicalIF":0.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical DiabetesPub Date : 2025-08-28eCollection Date: 2025-05-01DOI: 10.2337/cd25-0047
Tim C Lai, Heather P Whitley, Mesfin Genie, Robert H Eckel, Surachat Ngorsuraches
{"title":"Important Continuous Glucose Monitoring Attributes for Patients With Type 2 Diabetes.","authors":"Tim C Lai, Heather P Whitley, Mesfin Genie, Robert H Eckel, Surachat Ngorsuraches","doi":"10.2337/cd25-0047","DOIUrl":"10.2337/cd25-0047","url":null,"abstract":"<p><p>Although patient preferences are heterogeneous, the out-of-pocket cost and accuracy of continuous glucose monitoring (CGM) systems are the two most important attributes for patients with type 2 diabetes. Surprisingly, receiver screen information is not considered important when choosing a CGM system. Identifying important attributes could facilitate patient-provider communications in choosing a preferred CGM system and potentially increase adherence. Improving patient education on interpreting the information on the receiver screen could enhance the benefit of using CGM.</p>","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 5","pages":"670-680"},"PeriodicalIF":0.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical DiabetesPub Date : 2025-08-28eCollection Date: 2025-05-01DOI: 10.2337/cd25-0037
Pamela Kushner, Carlos Campos, Aaron King, Davida F Kruger, Javier Morales
{"title":"Clinician Guidance on the Benefits of Healthy Nutrition and Increased Physical Activity for People With Type 2 Diabetes Following Glucagon-Like Peptide 1 Receptor Agonist Initiation.","authors":"Pamela Kushner, Carlos Campos, Aaron King, Davida F Kruger, Javier Morales","doi":"10.2337/cd25-0037","DOIUrl":"10.2337/cd25-0037","url":null,"abstract":"<p><p>Glucagon-like peptide 1 (GLP-1) receptor agonists are prescribed as an adjunct to diet and exercise for the management of type 2 diabetes, yet adherence to healthy nutrition and physical activity is often suboptimal. As the use of these agents continues to rise, there are some concerns about the negative aspects of associated weight loss, including loss of muscle mass. This article highlights the benefits of healthy nutrition and physical activity for type 2 diabetes management irrespective of GLP-1 receptor agonist use or associated weight loss, identifies barriers to healthy nutrition and physical activity, and provides guidance for primary care clinicians to further educate and advise their patients on these important topics when initiating GLP-1 receptor agonist treatment.</p>","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 5","pages":"681-695"},"PeriodicalIF":0.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical DiabetesPub Date : 2025-08-27eCollection Date: 2025-05-01DOI: 10.2337/cd25-0065
Alice M Gregory, Partha Kar
{"title":"Smartphone-Free Childhood? Monitoring the Implications of Initiatives to Remove Smartphones for Children With Type 1 Diabetes.","authors":"Alice M Gregory, Partha Kar","doi":"10.2337/cd25-0065","DOIUrl":"10.2337/cd25-0065","url":null,"abstract":"","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 5","pages":"833-834"},"PeriodicalIF":0.0,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical DiabetesPub Date : 2025-08-20eCollection Date: 2025-01-01DOI: 10.2337/cd25-0015
Michelle Wang, Madhumita Sushil, Christopher Y K Williams, Brenda Y Miao, Sarah Kim, Umesh Masharani, Gregory Ku, Victoria Hsiao, Aloukika Shah, Suneil K Koliwad, Atul J Butte
{"title":"Assessment of Large Language Models for Enhancing Diabetologist-Developed Personalized Treatment Plans in Complex Type 2 Diabetes.","authors":"Michelle Wang, Madhumita Sushil, Christopher Y K Williams, Brenda Y Miao, Sarah Kim, Umesh Masharani, Gregory Ku, Victoria Hsiao, Aloukika Shah, Suneil K Koliwad, Atul J Butte","doi":"10.2337/cd25-0015","DOIUrl":"10.2337/cd25-0015","url":null,"abstract":"<p><p>Treatment decisions for type 2 diabetes are complex and multifactorial. This study evaluated the utility of OpenAI's generative pre-trained transformer-4 (GPT-4) large language model in enhancing treatment plans for people with diabetes. The authors assessed GPT-4's ability to extract and critically evaluate diabetologist-developed treatment plans from patients' clinical notes. GPT-4 accurately discerned personalized treatment goals but performed suboptimally when identifying plans that could be further improved and personalized. However, 40% of GPT-4's reasoning and explanations were still considered helpful by experienced academic diabetologists, suggesting a potential broad benefit to less expert physicians, such as those in primary care settings.</p>","PeriodicalId":39894,"journal":{"name":"Clinical Diabetes","volume":"43 4","pages":"545-553"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12547058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145379099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}