中国循证医学杂志最新文献

The application and promotion of electronic informed consent 电子知情同意的应用及推广

中国循证医学杂志 Pub Date : 2021-01-01 DOI: 10.7507/1672-2531.202102042

Y. Dong, L. Qin, W. Wu, C. Tang, W. Long, Z. Yang, L. Ling, L. Lu

引用次数: 1

Safety of COVID-19 vaccine: A meta-analysis COVID-19疫苗的安全性:一项meta分析

中国循证医学杂志 Pub Date : 2021-01-01 DOI: 10.7507/1672-2531.202102056

C. Liu, Yaolong Chen, S. Zhao, S. Dong, Y. Zhang, Y. Zhao, Q. Zhu, H. Jin

{"title":"Safety of COVID-19 vaccine: A meta-analysis","authors":"C. Liu, Yaolong Chen, S. Zhao, S. Dong, Y. Zhang, Y. Zhao, Q. Zhu, H. Jin","doi":"10.7507/1672-2531.202102056","DOIUrl":"https://doi.org/10.7507/1672-2531.202102056","url":null,"abstract":"Objective To systematically review the safety of different types of COVID-19 vaccines in the population. Methods Web of Science, PubMed, EMbase, The Cochrane Library, CNKI, WanFang Data and CBM databases were electronically searched to collect randomized controlled trials (RCTs) which reported safety of COVID-19 vaccines in population. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Meta-analysis was then performed by using RevMan 5.4 software. Results A total of 5 RCTs involving 2 431 subjects were included. The results of the meta-analysis showed that COVID-19 vaccines developed more fever symptoms than placebo (RR=2.21, 95%CI 1.38 to 3.54, P=0.000 9). However, there was no significant difference in the incidence of adverse reactions (RR=1.28, 95%CI 0.96 to 1.70, P=0.10), injection site adverse reactions (RR=1.47, 95%CI 0.65 to 3.36, P=0.36) and systemic adverse reactions (RR=0.96, 95%CI 0.78 to 1.17, P=0.66) between two groups. Conclusions Current evidence shows that COVID-19 vaccines are sufficiently safe. Due to limited quality and quantity of the included studies, more high-quality studies are required to verify the above conclusions. © 2021 West China University of Medical Science. All rights reserved.","PeriodicalId":39892,"journal":{"name":"中国循证医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71345533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The application of extracorporeal membrane oxygenation in patients with COVID-19: A systematic review and meta-analyses of cohort studies 体外膜氧合在COVID-19患者中的应用:队列研究的系统回顾和荟萃分析

中国循证医学杂志 Pub Date : 2021-01-01 DOI: 10.7507/1672-2531.202101122

S. Yi, M. Mingyuan, G. Qianqian, G. Liheng

{"title":"The application of extracorporeal membrane oxygenation in patients with COVID-19: A systematic review and meta-analyses of cohort studies","authors":"S. Yi, M. Mingyuan, G. Qianqian, G. Liheng","doi":"10.7507/1672-2531.202101122","DOIUrl":"https://doi.org/10.7507/1672-2531.202101122","url":null,"abstract":"Objective To systematically review the application of extracorporeal membrane oxygenation (ECMO) in patients with coronavirus disease 2019 (COVID-19). Methods PubMed, The Cochrane Library, EMbase, CBM, WanFang Data and CNKI databases were searched for studies on ECMO for COVID-19 from December 1st, 2019 to December 31st, 2020. Two researchers independently screened literature, extracted data, and evaluated the risk of bias of included studies. Meta-analysis was then performed using RevMan 5.3 software. Results A total of 24 studies were included, involving 1 576 acute respiratory distress syndrome (ARDS) patients with COVID-19. The overall mortality of patients was 27.3% (430/1 576). The rate of ECMO treatment was 4.68% (379/1 576), and the survival rate was 69.4% (263/379). The mean duration of mechanical ventilation prior to ECMO treatment for ARDS patients ranged from 2.07±0.40 to 15.89±13.0 days, compared with 1.64±0.78 days and 29.9±3.60 days for ECMO treatment. Of the 11 studies included in the meta-analysis, 84.0% (405/482) patients with ARDS received conventional treatment with COVID-19, and 16.0% (77/482) received ECMO treatment on the basis of conventional treatment with ARDS. Results of meta-analysis showed that there was statistically significant difference in the survival rate of ARDS patients with COVID-19 treated with conventional therapy combined with ECMO or with conventional therapy alone (RR=1.27, 95%CI 1.00 to 1.62, P=0.05). Conclusions This study suggests that the survival rate of COVID-19 patients after ECMO treatment has a tendency to improve. Due to the limitation of quantity and quality of included studies, the above conclusions are needed to be verified by more high-quality studies. © 2021 West China University of Medical Science. All rights reserved.","PeriodicalId":39892,"journal":{"name":"中国循证医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71345101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design of the master protocol platform trial and its application in related fields 主协议平台试验设计及其在相关领域的应用

中国循证医学杂志 Pub Date : 2021-01-01 DOI: 10.7507/1672-2531.202104005

Z. Guan, Y. Liu, J. Zhang, Yaolong Chen, H. Dai, X. Zhang, M. Hu, H. Shang

引用次数: 0

Public anticipation of clinician graduates in the new era of healthy China: A questionnaire-based cross-sectional study 健康中国新时代公众对临床医师毕业生的期望:一项基于问卷的横断面研究

中国循证医学杂志 Pub Date : 2021-01-01 DOI: 10.7507/1672-2531.202006087

X. Zheng, Xinran Sun, Q. Zhang, Q. Liu, Y. Yuan

{"title":"Public anticipation of clinician graduates in the new era of healthy China: A questionnaire-based cross-sectional study","authors":"X. Zheng, Xinran Sun, Q. Zhang, Q. Liu, Y. Yuan","doi":"10.7507/1672-2531.202006087","DOIUrl":"https://doi.org/10.7507/1672-2531.202006087","url":null,"abstract":"Objective The purpose of this study was to offer new suggestions for current clinician training under the guidance of the Healthy China 2030 policy by investigating the patients' needs. Methods This study surveyed adult outpatients from West China Hospital of Sichuan University between March and July, 2019 and February and May, 2020 by self-constructed questionnaires to investigate the expectation and requirements of outpatients towards medical professionals. Results A total of 430 questionnaires were distributed, and 402 of them (93.5%) were collected and included in this study. All questionnaire respondents expected that medical graduates should have outstanding expertise and ethical standard. The majority valued qualities such as physical and mental health (90.05%), a bachelor's degree or higher (73.88%), knowledge on disease control and prevention (61.69%), knowledge on health care (91.29%), ability to continuously update current knowledge (70.65%), and excellent communication (71.14%) and teamwork (62.44%) skills. In addition, most patients expected that new health care providers to possess humanitarianism and professional dedication relevant traits, and could improve diagnoses and treatments via research activities. Patients' demand for abilities such as disease control and prevention, health care, and integrative cooperation between traditional Chinese medicine and modern medicine significantly increased after the COVID-19 pandemic (P<0.05). Conclusions Nowadays, to provide health care services which meet the needs of the public, clinicians are expected to have qualities such as outstanding expertise, humanity, research and knowledge-updating skills, disease control and prevention, health care management, and capability to take the advantages of traditional Chinese medicine and modern medicine. © 2021 West China University of Medical Science. All rights reserved.","PeriodicalId":39892,"journal":{"name":"中国循证医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71345049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of depression and anxiety among health care workers in designated hospitals during the COVID-19 epidemic: A meta-analysis 2019冠状病毒病流行期间指定医院医护人员抑郁和焦虑患病率:一项荟萃分析

中国循证医学杂志 Pub Date : 2021-01-01 DOI: 10.7507/1672-2531.202105079

X. Liu, G. Wang, J. Zhang, S. Wang

{"title":"Prevalence of depression and anxiety among health care workers in designated hospitals during the COVID-19 epidemic: A meta-analysis","authors":"X. Liu, G. Wang, J. Zhang, S. Wang","doi":"10.7507/1672-2531.202105079","DOIUrl":"https://doi.org/10.7507/1672-2531.202105079","url":null,"abstract":"Objective To systematically review the prevalence of depression and anxiety among health care workers in designated hospitals during the COVID-19 pandemic. Methods The Cochrane Library, PubMed, EMbase, Web of Science, CNKI, WanFang Data, VIP, and CBM databases were electronically searched to collect cross-sectional studies on the prevalence of depression and anxiety among health care workers from December 2019 to April 2021. Two reviewers independently screened literature, extracted data, and assessed the risk of bias of the included studies. Meta-analysis was then performed using Stata 14.0 software. Results A total of 21 cross-sectional studies were included, involving 38 372 participants. Meta-analysis results showed that during the COVID-19 epidemic, the prevalence of depression and anxiety among health care workers in designated hospitals were 31.00% (95%CI 0.25 to 0.37) and 44.00% (95%CI 0.34 to 0.53). The results of subgroup analysis showed that individuals of female, married, bachelor degree or above, nurses, junior professional titles, and non-first-line medical staff had higher prevalence of depression and anxiety. Conclusions During the COVID-19 pandemic, the incidence of depression and anxiety among health care workers in designated hospitals remain high. Therefore, more attention should be paid to the mental health of health care workers in designated hospitals. Due to the limited quantity and quality of included studies, more high-quality studies are needed to verify the above conclusions. © 2021 West China University of Medical Science. All rights reserved.","PeriodicalId":39892,"journal":{"name":"中国循证医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71345601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Nosocomial infection prevention and control: Another main battlefield for new coronavirus pneumonia 医院感染防控:新冠肺炎又一主战场

中国循证医学杂志 Pub Date : 2020-10-01 DOI: 10.7507/1672-2531.202002029

Qi Wu

引用次数: 0

Emergency rescue of novel coronavirus pneumonia: Exploration from China 新型冠状病毒肺炎应急救援：来自中国的探索

中国循证医学杂志 Pub Date : 2020-07-01 DOI: 10.7507/1672-2531.202002010

Jie Jiang, Yongqing Yuan, Ting Cheng, J. Guo, Jiajie Yu, Youping Li

引用次数: 0

Development of rapid advice guidelines in public health emergency 制定突发公共卫生事件快速咨询准则

中国循证医学杂志 Pub Date : 2020-05-01 DOI: 10.7507/1672-2531.202003097

Yaolong Chen, Xianzhuo Zhang, Ling Wang, Qi Wang, Xufei Luo, Yanfang Ma, E. Liu, Z. Luo, Qiu Li, Z. Fu, Weiguo Li