Medical Technologies Journal最新文献

{"title":"Novel design of optical sensor based on two-dimensional photonic crystals for the detection of volatile organic compounds that can infect human health","authors":"Ghoumazi Mehdi, A. Hocini, Massaoud Hameurlain, Mokhtar Boudaa","doi":"10.26415/2572-004X-VOL2ISS4P293-300","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS4P293-300","url":null,"abstract":"Background: In recent research, optical sensors gained a growing interest motivated by the increasing need for specific sensors that allow for routine and effective measurements in several fields and analysis such as, safety, environment, and human health. Among optical sensors are photonic crystal sensors, which are characterized by high sensitivity and biocompatibility. The variations inside and around the photonic crystal can give important information by measuring the wavelength, the band gap, the output power…etc. Through defects created in photonic crystals such as missing rows of holes or rods, light is guided through and the goal is to achieve a very high sensitivity and spatial selectivity to changing superior bulk devices. In this study, we model a new structure of an optical channel drop filter (CDF) based on 2-dimensional photonic crystals to detect volatile organic compounds that can infect human health. \u0000Objective: Detect the variation of the refractive index by fixing the radius (r) at 99.37nm and the lattice constant (a) at 523nm for various volatile organic compounds such as H2CO, CH2Cl2, and C2Cl4 with refractive indexes that are: 1.3746, 1.421 and 1.503 respectively in the optical sensor based on photonic crystals for reasons related to the protection of human health. \u0000Methods: The structure is made of square lattice silicon rods immersed in air. The dielectric constant of silicon and air is 11.9716 and 1 respectively. First, we created a cross shape resonator and designed an optical channel drop filter in the heart of the structure; our method is based on plane wave expansion method (PWE) by using MATLAB software and the finite element method (F.E.M) with COMSOL software. \u0000Results: Three volatile compounds have been studied, such as Dichloromethane used as synthesis intermediate by the chemical industry or solvent used in the pharmaceutical or medical industry. Acute inhalation exposure may cause severe optic neuropathy and liver attack (Hepatitis). Then, the Methanal is used to dry or kill the skin taking as an example, the medical treatment of warts. And perchlorethylene is used for the dry cleaning of tissues and for degreasing metals because it is in category 3 carcinogens, toxic to the nervous system and the kidney. These three volatile compounds where introduced and studied in the proposed structure. The results obtained through this study are as follows: \u0000 \u0000diagram of the TM and TE bands of the photonic crystal in a square array of silicon rods embedded in the air, \u0000schematic diagram of the filter, \u0000distribution of the refractive index along the structure, \u0000structure meshing, \u0000propagation and transmission for different refractive indices such as methanal (H2CO), dichloromethane (CH2Cl2) and perchlorethylene (C2Cl4). \u0000 \u0000Conclusion: In this article, we have been able to simulate, analyze and control our proposed structure with MATLAB and COMSOL software based on the finite element method. The results show that for the thr","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125632468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of New inhibitors of the FibrillogenesisAß42: Alzheimer’s Disease","authors":"Assia Keniche","doi":"10.26415/2572-004x-vol2iss4p315-315","DOIUrl":"https://doi.org/10.26415/2572-004x-vol2iss4p315-315","url":null,"abstract":"Background: The Alzheimer’s disease (AD) is a devastating neurodegenerative disorder and the most common cause of dementia. The pathological hallmarks of AD are the presence of neurofibrillary tangles and amyloid deposits in the brain of the patient, as already defined by Alois Alzheimer in 1907. The aim of our study is to inhibit the formation the folding of amyloid protein by new synthesis of b-sheet breaker peptides. \u0000Methods: Our approach consist to develop b-sheet breaker peptides as a novel strategy to inhibit and reverse amyloidosis in AD. The synthesis was down by peptid coupling method. \u0000Results: Several b-sheet breaker peptides have been designed based on the hypothesis that amyloid deposition could be inhibited by short synthetic peptides partially homologous to the Ab region undergoing conformational changes to give rise to the amyloidogenic Ab intermediate and containing residues disrupting as aziridine and CD for the b-sheet formation university Tlemcen 2017. \u0000Conclusion:At present, there is no ideal drug for the treatment of AD, and the searches for AD drugs remain an urgent issue in the pharmaceutical community. Due to its complex pathogenesis, a single target drug cannot cure this disease fundamentally. Dual or multiple target drugs involved in two or more aspects of AD pathogenesis may generate a synergistic effect and ultimately achieve an ideal therapeutic effect.","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127675848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health 4.0: Applications, Management, Technologies and Review","authors":"Abdeldjalil Khelassi, Vania V. Estrela, Ana Carolina Borges Monteiro, R. P. França, Y. Iano, Navid Razmjooy","doi":"10.26415/2572-004X-VOL2ISS4P262-276","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS4P262-276","url":null,"abstract":"The Industry 4.0 Standard (I4S) employs technologies for automation and data exchange through cloud computing, Big Data (BD), Internet of Things (IoT), forms of wireless Internet, 5G technologies, cryptography, the use of semantic database (DB) design, Augmented Reality (AR) and Content-Based Image Retrieval (CBIR). Its healthcare extension is the so-called Health 4.0. \u0000This study informs about Health 4.0 and its potential to extend, virtualize and enable new healthcare-related processes (e.g., home care, finitude medicine, and personalized/remotely triggered pharmaceutical treatments) and transform them into services. \u0000In the future, these services will be able to virtualize multiple levels of care, connect devices and move to Personalized Medicine (PM). The Health 4.0 Cyber-Physical System (HCPS) contains several types of computers, communications, storage, interfaces, biosensors, and bioactuators. The HCPS paradigm permits observing processes from the real world, as well as monitoring patients before, during and after surgical procedures using biosensors. Besides, HCPSs contain bioactuators that accomplish the intended interventions along with other novel strategies to deploy PM. A biosensor detects some critical outer and inner patient conditions and sends these signals to a Decision-Making Unit (DMU). Mobile devices and wearables are present examples of gadgets containing biosensors. Once the DMU receives signals, they can be compared to the patient’s medical history and, depending on the protocols, a set of measures to handle a given situation will follow. The part responsible for the implementation of the automated mitigation actions are the bioactuators, which can vary from a buzzer to the remote-controlled release of some elements in a capsule inside the patient’s body. \u0000            Decentralizing health services is a challenge for the creation of health-related applications. Together, CBIR systems can enable access to information from multimedia and multimodality images, which can aid in patient diagnosis and medical decision-making. \u0000Currently, the National Health Service addresses the application of communication tools to patients and medical teams to intensify the transfer of treatments from the hospital to the home, without disruption in outpatient services. \u0000HCPS technologies share tools with remote servers, allowing data embedding and BD analysis and permit easy integration of healthcare professionals expertise with intelligent devices.  However, it is undeniable the need for improvements, multidisciplinary discussions, strong laws/protocols, inventories about the impact of novel techniques on patients/caregivers as well as rigorous tests of accuracy until reaching the level of automating any medical care technological initiative.","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129934870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designing and Implementing a Telemedicine System","authors":"A. Sebaa, Hachemi Atroune, Koceila Chefai, Nesrine Hammouche, Yamina Khiati, Lydia Abbas","doi":"10.26415/2572-004X-VOL2ISS4P277-284","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS4P277-284","url":null,"abstract":"Background: A modern tele-consultation system improves patients’ monitoring and favors remote assistance in terms of facilitating the daily life to the patients. The aim of this work is to design and implement a modern remote consultation system. \u0000Methods: To achieve this work, we identify the actors who interact with the system to be developed and the use cases relating to each actor. A class model is designed to derive the relational model and the corresponding database. During implementation, we have used PHP language and MySQL database system. \u0000Results: A tele-consultation framework is implemented. The users (patients and doctors) must register then authenticate in order to use the system. The latter allows them audio and video conversation between them. \u0000Conclusion: We have given in this study how to design and implement a telemedicine system which will improve health care, ensure continuity of home care, prevent complications and thus limit hospitalizations and limit medical travel.","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124642499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between MTHFR C677T gene polymorphism and essential hypertension in a sample of an Algerian population of the Oran city","authors":"Asma Amrani-Midoun","doi":"10.26415/2572-004X-VOL2ISS4P314-314","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS4P314-314","url":null,"abstract":"Background \u0000Many studies have investigated the role of 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism in essential hypertension (EH), but with conflicting results. \u0000Aim \u0000To determine the eventual association between 5,10-methylenetetrahydrofolate reductase (MTHFR ) C677T gene polymorphism and hypertension in a sample of Algerian population from the Oran city. \u0000Methods \u0000A case-control study has been performed in 154 subjects including 82 hypertensives defined as subjects with elevated systolic blood pressure SBD140mmHg and or sustained diastolic blood pressure DBP≥90mmHg, and 72 normotensive subjects. Polymerase chain reaction (PCR) combined with restrictive fragment length polymorphism (RFLP) was used to detect the MTHFR C677T variant. \u0000Results \u0000We observe no significant differences between allelic and genotypic frequencies between cases and controls for C677T polymorphism (OR=1.51, 95% CI= 0.89-2.56, P=0.13). Analyses adjusted for age, sex and body mass index improved the association level, though the association was still not significant (30% vs. 22%, OR=1.75, 95% CI= 0.95-3.24, P=0.07). \u0000  \u0000  \u0000Conclusion \u0000This work showed that genetic polymorphism related to the MTHFR gene (C677T) is not associated with the risk of hypertension in this sample of Algerian population. Larger case- control samples are required to clearly assess the role of this genetic variant in EH. \u0000Keywords: MTHFR C677T gene polymorphism; hypertension; Algerian population; case-control study.","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132193979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feature extraction and segmentation of medical images for MRI and Digital mammogram","authors":"Mehdi Tinhinane, A. Boudrioua, Abdelouhab Aloui","doi":"10.26415/2572-004X-VOL2ISS4P308-313","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS4P308-313","url":null,"abstract":"Developing a computer aided diagnosis system (CAD) is an extremelychallenging task. One of the major goals of CAD is to help the radiologist to makegood decisions by detecting and analyzing characteristics of benign and malignant lesions. In this context, we present accurate and automatic method that, detect and extract malignancy descriptors of breast and meningioma brain tumor.Our applied an algorithm that uses enhancement image based on homomorphicfiltering and adaptive histogram equalization technique. This work was proposedby Zhang Chaofu et al. [3]. A region of interest is determinated using K meansclustering. And then, we employed basically wavelet transform to extract pertinent features for meningioma tumor, geometric and texture characteristics forbreast tumor in order to classify malignancy lesion.","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"13 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131067502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward a Full Integration of the Arabic Language into ‘Intel ACAT’ Assitive Platform","authors":"Zakariya Ahmed Nadji, Boudour Rachid, A. Souahi","doi":"10.26415/2572-004X-VOL2ISS4P285-292","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS4P285-292","url":null,"abstract":"Background:Assisting people with severe physical limitations with information technology has been an active area of research in recent years. Many researchers’ efforts are built on assistive devices which are often used to offset the impact of the resulted physical impairments.The Assistive Context-Aware Toolkit (ACAT) is the widely known project in this area. After being released as open source, the developers’ community helped to integrate many languages such as French and Spanich. However, many languages are still messing and to the best of our knowledge, the Arabic-speaking users still can not use the platform as no significant effort to integrate the Arabic language have been previously undertaken.Methods:This paper firstly, provides an overview on ACAT; the specifically-developed platform by Intel Labs for Dr. Stephen Hawking. Besides, it describes the ways in which ACAT may be used to enhance the capacity to take part in fundamental and instrumental activities of every day living and upgrade one's autonomy in general.Secondly, we outline our contributions in integrating the Arabic language into the keyboard, the intelligent predictive text engine and all interfaces of this unique and highly configurable system. Results:Our integration evolved after resolving many issues and we succeeded in integrating the Arabic language in interfaces, keyboard and word prediction engine. Most of other ACAT features (Facial gesture recognition, Mouse Navigation., etc) are functional. \u0000Conclusion:This work is a step forward to make the intel ACAT platform completely available in Arabic language. Therefore, Arabic-speaking patient can now get the benefits from this platform and are able to perform common tasks such as documents editing and management, Web surfing, writing emails and above all, communicating with others easily.The Arabic Text-to-speech engine integration is planned for future works .","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121100729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automatic Human Sperm Concentrartion in microscopic videos","authors":"K. Boumaza, A. Loukil, Kaouthar Aarizou","doi":"10.26415/2572-004X-VOL2ISS4P301-307","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS4P301-307","url":null,"abstract":"Abstract \u0000Background: Human sperm cell counting analysis is of significant interest to biologists studying sperm function and to medical practitioners evaluating male infertility. Currently the analysis of this assessment is done manually by looking at the sperm samples through a phase-contrast microscope using expert knowledge to do a subjective judgement of the quality. \u0000Aims: to eliminate the subjective and error prone of the manual semen analysis and to avoid inter and intra-laboratory inconsistencies in semen analysis test results \u0000Methods: In this paper we introduce a technique for human sperm concentration. Its principle is based on the execution of three steps: The first step in unavoidable. It concerns the pretreatment of the human sperm microscopic videos which consists of a conversion of the RGB color space into the YCbCr space, the “Gaussian filtering” and the “discrete wavelet filtering”. The second step is devoted to the segmentation of the image into two classes: spermatozoas and the background. To achieve this, we used an edge detection technique “Sobel Contour detector”. The third step is to separate true sperm from false ones. It uses a machine learning technique of type decision trees that consist on two classes classification based on invariant characteristics that are the dimensions of the bounding ellipse of the spermatozoid head as well as its surface. \u0000Results: To test the robustness of our system, we compared our results with those performed manually by andrologists. After results analysis, we can conclude that our system brings a real improvement of precision as well as treatment time which make it might be useful for groups who intend to design new CASA systems. \u0000Conclusion: In this study, we designed and implemented a system for automatic concentration assessment based on machine learning method and image processing techniques.","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132739594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impedance cardiography technique in medical diagnosis","authors":"Hadjer Benabdallah, S. Kerai","doi":"10.26415/2572-004X-VOL2ISS3P232-244","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS3P232-244","url":null,"abstract":"Background: Thoracic Electrical Bioimpedance (TEB) Technology sometimes called the Impedance Cardiography (ICG).  In 1940, the Impedance Cardiography emerged; the studies of this technique are realized to the cardiovascular diseases detection which used hemodynamic parameters measurements based on the skin electrodes contact by injecting a low amplitude alternating signal. The objective of this article is to review the various studies based on this signal type and to present the multiple methods used for the treatment and to have a correct analysis. \u0000Methods: This ICG technique consists for applying an electric field longitudinally across a segment of the thorax with amplitude in mean, high frequency and low amplitude current. To analyze the ICG signal, the signal denoising is necessary that’s why a multiple filters are proposed, and the Discrete Wavelet Transform (DWT) denoising is also used. \u0000Results: The ICG is considered advantageous compared to other invasive conventional techniques; it gives a good correlation, and solves the Doppler ultrasound and Thermodilution problems. According to the studies, the Daubechies wavelet family (db8) is the best DWT to eliminate the noises. There are several algorithms for the signal characteristic point’s detection. \u0000Conclusion: For the purpose of cardiovascular disease diagnosis and monitoring, the non-invasive ICG technique comes to solve the complexity problem for measurement and analyzing heart disease based on the thoracic electrical impedance change assessment that is due to blood velocity and resistivity changes (blood volume changes) in order to estimate several hemodynamic parameters. \u0000Keywords: ICG, cardiovascular disease, hemodynamic parameters, diagnosis and monitoring, correct analysis.","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117130297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new approach for breast abnormality detection based on thermography","authors":"Chebbah Nabil Karim, Ouslim Mohamed, Temmar Ryad","doi":"10.26415/2572-004X-VOL2ISS3P245-254","DOIUrl":"https://doi.org/10.26415/2572-004X-VOL2ISS3P245-254","url":null,"abstract":"Breast cancer is one of the most common women cancers in the world. In this paper, a new approach based on thermography for the early detection of breast abnormality is proposed. The study involved 80 breast thermograms collected from the PROENG public database which consists of 50 healthy breasts and 30 with some findings. Image processing techniques such as segmentation, texture analysis and mathematical morphology were used to train a support vector machine (SVM) classifier for automatic detection of breast abnormality. After conducting several tests, we obtained very interesting and motivating results. Indeed, our method  showed a high performance in terms of sensitivity of 93.3%, a specificity of 90% and an accuracy of 91.25%. The final results let us conclude that infrared thermography with the help of an adequate automatic classification algorithm can be a valuable and reliable complementary tool for radiologist in detecting breast cancer and thereby helping to reduce mortality rates.","PeriodicalId":397681,"journal":{"name":"Medical Technologies Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128621365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}