Revista Espanola de Cirugia Ortopedica y Traumatologia最新文献

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Superior Capsular Reconstruction of the Shoulder with Long Head of Biceps Autograft vs. Achilles Tendon Allograft: A 2-Year Comparative Study. 肱二头肌长头自体移植物与跟腱异体移植物的肩关节上囊重建术:两年对比研究
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-14 DOI: 10.1016/j.recot.2024.11.023
Diego José Gómez, Santiago Ávila Posada, Nadia Gabotto, Gonzalo Viollaz, Álvaro Muratore, Nicolás Nohad Altamirano, Daniel Moya
{"title":"Superior Capsular Reconstruction of the Shoulder with Long Head of Biceps Autograft vs. Achilles Tendon Allograft: A 2-Year Comparative Study.","authors":"Diego José Gómez, Santiago Ávila Posada, Nadia Gabotto, Gonzalo Viollaz, Álvaro Muratore, Nicolás Nohad Altamirano, Daniel Moya","doi":"10.1016/j.recot.2024.11.023","DOIUrl":"https://doi.org/10.1016/j.recot.2024.11.023","url":null,"abstract":"<p><strong>Purpose: </strong>To retrospectively evaluate the clinical-functional outcomes, healing rates, complications, and surgical time in patients treated with superior capsular reconstruction (SCR) using long head of the biceps autograft (LHB) and Achilles allograft (AA).</p><p><strong>Materials and methods: </strong>This retrospective study included 24 patients with irreparable rotator cuff tears of the supraspinatus and infraspinatus, treated with SCR. Two treatment groups were formed: one with 12 cases using AA and another with 12 cases using LHB. All patients were followed for a minimum of 2 years.</p><p><strong>Results: </strong>The SSV was 73.7 ± 25.3 vs. 86.0 ± 8.7 (p=0.26), the Constant score was 76.8 ± 20.1 vs. 83.7 ± 4.6 (p=0.12), and the VAS was 1.6 ± 2.3 vs. 1.7 ± 0.5 (p=0.9) for the LHB and AA groups, respectively. Tendon healing was 66.7% in AA and 100% in LHB (p=0.001). Complications were 50% in AA and 0% in LHB. The average surgical time was 127.7 ± 37.6 minutes for AA and 84.3 ± 14.3 minutes for LHB (p=0.01).</p><p><strong>Conclusions: </strong>SCR with LHB showed better results in terms of tendon healing, fewer complications, and reduced surgical time compared to the use of AA.</p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcultural validation of the risk assessment and predictor tool (RAPT) to Spanish. 风险评估和预测工具 (RAPT) 在西班牙文中的跨文化验证。
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-13 DOI: 10.1016/j.recot.2024.11.024
A Pérez-Perdomo, M Rivero, M Bassas, C Bordanove, E Ripoll-Romero
{"title":"Transcultural validation of the risk assessment and predictor tool (RAPT) to Spanish.","authors":"A Pérez-Perdomo, M Rivero, M Bassas, C Bordanove, E Ripoll-Romero","doi":"10.1016/j.recot.2024.11.024","DOIUrl":"10.1016/j.recot.2024.11.024","url":null,"abstract":"<p><strong>Objective: </strong>Translation and validation of the risk assessment and prediction tool (RAPT) into Spanish to assess the discharge needs of patients after total hip arthroplasty.</p><p><strong>Methodology: </strong>The original RAPT instrument was translated into Spanish following the guidelines of Sousa and Rojjanasrirat, 2011. To carry out the cross-cultural adaptation of the instrument to Spanish, the translation method of Guillermin et al., 1993 was used.</p><p><strong>Results: </strong>One hundred and thirty-four patients were included. The mean age was 71.6 years. Of the patients analyzed in the study, the tool detected that 57.8% required home rehabilitation, 28.9% would be discharged home and 13.3% would require an assessment from the social worker to go to a social health center. The content validity index (CVI) for the entire scale was 0.91. Cronbach's alpha was 0.84.</p><p><strong>Conclusions: </strong>The RAPT tool has been shown to be highly effective in assessing patients' needs upon discharge. According to the results of the study, 94.2% of the needs identified by the tool coincided with the real needs of the patients. This suggests that the tool may be an efective tool for planning post-discharge care.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful prophylactic measures for the eradication of Staphylococcus aureus infections in elective hip primary and revision arthroplasty.
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-09 DOI: 10.1016/j.recot.2024.12.010
J C Perdomo-Lizarraga, A Combalia, J A Fernández-Valencia, A Alías, J Aponcio, L Morata, A Soriano, E Muñoz-Mahamud
{"title":"Successful prophylactic measures for the eradication of Staphylococcus aureus infections in elective hip primary and revision arthroplasty.","authors":"J C Perdomo-Lizarraga, A Combalia, J A Fernández-Valencia, A Alías, J Aponcio, L Morata, A Soriano, E Muñoz-Mahamud","doi":"10.1016/j.recot.2024.12.010","DOIUrl":"10.1016/j.recot.2024.12.010","url":null,"abstract":"<p><strong>Introduction: </strong>Staphylococcus aureus stands as the predominant etiological agent in postoperative acute prosthetic joint infections (PJI), contributing to 35-50% of reported cases. This study aimed to evaluate the efficacy of dual prophylaxis incorporating cefuroxime and teicoplanin, in combination with nasal decolonization utilizing 70% alcohol, and oral and body lavage with chlorhexidine.</p><p><strong>Material and methods: </strong>We conducted a retrospective review of electronic health records regarding primary and revision arthroplasties conducted at our institution from 2020 to 2021. Relevant variables linked to prosthetic joint infections (PJI) were documented until the latest follow-up.</p><p><strong>Results: </strong>A total of 539 operations (447 primary arthroplasties and 92 revision arthroplasties) were performed on 519 patients. There were 11 cases of postoperative acute PJI, resulting in infection rates of 1.6% for primary arthroplasties and 4.3% for revision surgeries. Infections were more prevalent in male patients, individuals with an ASA classification>II, and those undergoing longer operations (>90min). S. aureus was not isolated in any of the cases.</p><p><strong>Conclusion: </strong>The prophylactic measures implemented in our institution have exhibited a high efficacy in preventing postoperative acute PJI caused by S. aureus.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Translated article] The importance of online presence and best practices for the orthopedic surgeon in social media.
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-09 DOI: 10.1016/j.recot.2024.12.003
M Vázquez Gómez, M Galipienso Eri, J Dellonder Frigolé, A Hernández Martínez
{"title":"[Translated article] The importance of online presence and best practices for the orthopedic surgeon in social media.","authors":"M Vázquez Gómez, M Galipienso Eri, J Dellonder Frigolé, A Hernández Martínez","doi":"10.1016/j.recot.2024.12.003","DOIUrl":"10.1016/j.recot.2024.12.003","url":null,"abstract":"","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Translated article] Use of semi-constrained total knee arthroplasty in gonarthrosis with collateral ligament insufficiency: Clinical and functional outcomes.
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-07 DOI: 10.1016/j.recot.2024.12.007
A Garrido-Hidalgo, R García Crespo, B Rizo de Álvaro, B Alcobía-Díaz, G Aparicio, F Marco
{"title":"[Translated article] Use of semi-constrained total knee arthroplasty in gonarthrosis with collateral ligament insufficiency: Clinical and functional outcomes.","authors":"A Garrido-Hidalgo, R García Crespo, B Rizo de Álvaro, B Alcobía-Díaz, G Aparicio, F Marco","doi":"10.1016/j.recot.2024.12.007","DOIUrl":"https://doi.org/10.1016/j.recot.2024.12.007","url":null,"abstract":"<p><strong>Introduction: </strong>Achieving stability in total knee arthroplasty (TKA) is crucial for long-term implant survival. In cases of severe deformity or ligament laxity, constrained implants may be required. Traditionally, increasing constraint involved intramedullary stems. However, there are intermediary alternatives, including employing a constrained polyethylene insert without stems, thereby avoiding complications related to them. The study aims to evaluate our experience with a non-modular constrained (NMC) implant in primary TKA.</p><p><strong>Material and methods: </strong>We conducted a retrospective review of the clinical and radiographic outcomes of 108 non-stemmed primary TKAs performed at our institution between 2013 and 2021 in patients with at least 10° deformity or 10 mm ligament laxity. Data included demographics, preoperative and postoperative deformities, clinical outcomes and revision rates.</p><p><strong>Results: </strong>A total of 103 patients (108 knees) with a mean age of 74 were followed up for a minimum of 2 years. The mean postoperative range of motion was 105°/0°. The median Oxford Knee Score, Knee Society Score and Knee Society Function Score were 43.5, 92 and 90, respectively. 17 knees had varus deformity (mean tibiofemoral angle of 2.7°), and 87 knees had excessive valgus deformity (mean tibiofemoral angle of 15.1°). The remaining 4 knees had a neutral alignment. The mean postoperative tibiofemoral angle was 6.8°. The overall revision rate was 6.5% (7 patients): 3 deep periprosthetic infections, 2 patellar dislocations, 1 stiffness and 1 aseptic loosening.</p><p><strong>Conclusion: </strong>Our experience demonstrates favorable mid-term outcomes with the NMC implant, providing a safe alternative to stemmed implants in primary TKA, particularly in cases of severe deformity or ligament laxity.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Artículo traducido] Proyecto AVIP (Amigo VIrtual Protésico): estudio de resultados clínico-funcionales y de satisfacción con una aplicación móvil en el manejo perioperatorio y seguimiento de implantes protésicos de cadera.
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-07 DOI: 10.1016/j.recot.2024.12.006
J Diranzo-García, V Estrems-Díaz, J F Garrido-Ferrer, L Castillo-Ruipérez, V M Zarzuela-Sánchez, L Hernández-Ferrando
{"title":"[Artículo traducido] Proyecto AVIP (Amigo VIrtual Protésico): estudio de resultados clínico-funcionales y de satisfacción con una aplicación móvil en el manejo perioperatorio y seguimiento de implantes protésicos de cadera.","authors":"J Diranzo-García, V Estrems-Díaz, J F Garrido-Ferrer, L Castillo-Ruipérez, V M Zarzuela-Sánchez, L Hernández-Ferrando","doi":"10.1016/j.recot.2024.12.006","DOIUrl":"https://doi.org/10.1016/j.recot.2024.12.006","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the clinical, quality of life, and healthcare quality outcomes obtained in a series of patients undergoing total hip arthroplasty (THA), who were empowered and monitored using the AVIP application. These results will be compared with a control group followed through a standard protocol.</p><p><strong>Material and method: </strong>Randomized clinical trial with parallel groups involving patients with an indication for THA. Clinical variables were measured and compared using the WOMAC and mHHS, pain assessed by the VAS, quality of life with the SF-12 test. Walking capabilities were analyzed using the Functional Gait Assessment Scale, along with satisfaction levels assessed through the SUCE questionnaire, and perceived anxiety levels related to the process.</p><p><strong>Results: </strong>A total of 68 patients were evaluated, with 31 patients in the AVIP group and 33 in the Control group completing the follow-up. Both groups demonstrated improvement in clinical outcomes based on the WOMAC and mHHS hip tests, a reduction in perceived pain, and an enhancement in quality of life according to the SF-12 test. Patients in the AVIP study group exhibited non-inferiority in clinical outcomes and satisfaction compared to the control group, as well as lower anxiety levels and improved walking capabilities after the first month of follow-up. Notably, 82.25% of the follow-up visits for this group were conducted remotely.</p><p><strong>Conclusion: </strong>The implementation of a mHealth application like AVIP can be safely offered to selected patients undergoing hip arthroplasty, enabling effective monitoring and providing continuous information and training.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Artículo traducido] Reemplazo total de cadera en pacientes menores de 50 años: ¿tiene la fijación no cementada mejores resultados?
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-07 DOI: 10.1016/j.recot.2024.12.008
L Perez Alamino, G Garabano, J Rodriguez, F Lopreite, C Pesciallo
{"title":"[Artículo traducido] Reemplazo total de cadera en pacientes menores de 50 años: ¿tiene la fijación no cementada mejores resultados?","authors":"L Perez Alamino, G Garabano, J Rodriguez, F Lopreite, C Pesciallo","doi":"10.1016/j.recot.2024.12.008","DOIUrl":"https://doi.org/10.1016/j.recot.2024.12.008","url":null,"abstract":"<p><strong>Background: </strong>Cementless fixation for hip arthroplasties has increased in the last decades, particularly in younger patients. The purpose of this study was to compare the long-term results of three different types of fixations in patients under 50 years old.</p><p><strong>Methods: </strong>Cemented, hybrid and cementless fixations were assessed in patients under 50 years old with a minimum follow-up of 8 years. Loosening, demarcation, complications, and prosthesis survival were assessed. Functional analysis was performed with the modified Harris Hip Score and Visual analogue scale was collected.</p><p><strong>Results: </strong>Final series consisted in 222 patients. Significant improvement was observed regarding mHHS and VAS score in each group. We observed statistically significant difference regarding demarcation between the groups (P < .001). The higher rate of acetabular and femoral stem loosening was observed in the cemented (20.0%) and hybrid (18.9%) group. The lowest prosthesis survival rate after 16 years was observed in hybrid group (P < .001).</p><p><strong>Conclusion: </strong>Total hip replacement has good long-term clinical and functional outcomes. The lowest rate of prosthesis survival was observed in hybrid group with 84.2% after 16 years.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Artículo traducido] Ensayo clínico aleatorizado sobre la utilidad de la impresión 3D en las fracturas intraarticulares de radio distal.
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-07 DOI: 10.1016/j.recot.2024.12.002
P Á Sebastián Giraldo, M Elvira Soler, A Fernández Kang, F Martínez Martínez, A García López
{"title":"[Artículo traducido] Ensayo clínico aleatorizado sobre la utilidad de la impresión 3D en las fracturas intraarticulares de radio distal.","authors":"P Á Sebastián Giraldo, M Elvira Soler, A Fernández Kang, F Martínez Martínez, A García López","doi":"10.1016/j.recot.2024.12.002","DOIUrl":"https://doi.org/10.1016/j.recot.2024.12.002","url":null,"abstract":"<p><strong>Objectives: </strong>We evaluated the utility of 3 D printing technology for preoperative planning in the treatment of intra-articular fractures of the distal radius in relation to the improvement of surgical technique, radiological and clinical results.</p><p><strong>Material and methods: </strong>A total of 30 patients with 2 B and C fractures of the AO classification were operated on by a single surgeon with a volar plate, randomly divided into two groups, 15 of them with conventional planning (Rx and CT) and 15 adding a 3 D model of the fracture and the previous simulation of the intervention. Simulation time, surgical time in minutes, radioscopy time in minutes, loss of material expressed in lost screws were recorded. Clinical evaluation based PRWE questionnaire and full radiographic analysis was done for all patients with a mean follow-up of 6 months by an independent, blinded observed.</p><p><strong>Results: </strong>No statistically significant differences were observed in the PRWE questionnaire (p = 0.22), nor were we observed differences in the radiological values, except in relation to the articular step (p = 0.028), which represents statistical significance, but in both groups the median was of 0.0 (0.0-0.0). We also did not see statistically significant differences in surgical times (p = 0.745), radioscopy (p = 0.819) or in the loss of synthesis material (p = 0.779).</p><p><strong>Conclusions: </strong>3 D printing has not improved the parameters studied in relation to routinely operated patients.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Técnica quirúrgica del manejo de las fracturas de calcáneo a través de un abordaje del seno del tarso.
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-07 DOI: 10.1016/j.recot.2024.12.004
J Mingo-Robinet, L González-García, C González-Alonso
{"title":"Técnica quirúrgica del manejo de las fracturas de calcáneo a través de un abordaje del seno del tarso.","authors":"J Mingo-Robinet, L González-García, C González-Alonso","doi":"10.1016/j.recot.2024.12.004","DOIUrl":"https://doi.org/10.1016/j.recot.2024.12.004","url":null,"abstract":"<p><p>Calcaneal articular fractures are fractures classically associated with a high rate of complications and poor outcomes. Osteosynthesis of the calcaneus through a sinus tarsi approach has shown results equal to or superior to those of the extended approach, having become the new gold standard.The objective: of this article is to detail step by step the surgical technique of osteosynthesis of intra-articular fractures of the calcaneus through a sinus tarsi approach, from the selection of the fracture, positioning of the patient, layout of the operating room and the fluoroscope, the entire surgical process until postoperative treatment.The surgical technique described below is described in 6 steps.Layout of the operating room. Patient and Fluoroscope Positioning.Reduction of the posterior tuberosity (correct height and varus).Sinus tarsi approach.Reduction of the articular surface and correct visualization. Arthroscopy.Fixation of the articular surface.Fixation of the posterior tuberosity.Anatomical reduction of complex calcaneal fractures through an Sinus Tarsi Approach requires an understanding of the fracture and its associated deformities. Following the described sequence step by step will help to achieve a better reduction in order to achieve better functional results.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Translated article] Efficacy of new active viscosupplements on the behaviour of an experimental model of osteoarthritis.
Revista Espanola de Cirugia Ortopedica y Traumatologia Pub Date : 2024-12-07 DOI: 10.1016/j.recot.2024.12.009
R E Pérez Expósito, M A Ortega Núñez, M J Buján Varela, R M Vega Rodríguez, A I Ortíz Chércoles, B J De La Torre Escuredo
{"title":"[Translated article] Efficacy of new active viscosupplements on the behaviour of an experimental model of osteoarthritis.","authors":"R E Pérez Expósito, M A Ortega Núñez, M J Buján Varela, R M Vega Rodríguez, A I Ortíz Chércoles, B J De La Torre Escuredo","doi":"10.1016/j.recot.2024.12.009","DOIUrl":"10.1016/j.recot.2024.12.009","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate with an animal model of osteoarthritis (New Zealand rabbits) the effectiveness of treatment with active viscosupplements (hyaluronic acid loaded with nanoparticles (NPs) that encapsulate anti-inflammatory compounds or drugs.</p><p><strong>Material and methods: </strong>Experimental study composed of 5 groups of rabbits in which section of the anterior cruciate ligament and resection of the internal meniscus were performed to trigger degenerative changes and use it as a model of osteoarthritis. The groups were divided into osteoarthrosis without treatment (I), treatment with commercial hyaluronic acid (HA) (II), treatment with HA with empty nanoparticles (III), treatment with HA with nanoparticles encapsulating dexamethasone (IV) and treatment with HA with nanoparticles that encapsulate curcumin (V). In groups II-V, the infiltration of the corresponding compound was carried out spaced one week apart. Macroscopic histological analysis was performed using a scale based on the Outerbridge classification for osteoarthritis.</p><p><strong>Results: </strong>We observed that this osteoarthritis model is reproducible and degenerative changes similar to those found in humans are observed. The groups that were infiltrated with hyaluronic acid with curcumin-loaded nanoparticles (V), followed by the dexamethasone group (IV) presented macroscopically less fibrillation, exposure of subchondral bone and sclerosis (better score on the scale) than the control groups (I) (osteoarthritis without treatment), group (II) treated with commercial hyaluronic acid and hyaluronic acid with nanoparticles without drug (III).</p><p><strong>Conclusions: </strong>The use of active viscosupplements could have an additional effect to conventional hyaluronic acid treatment due to its antioxidant and anti-inflammatory effect. The most promising group was hyaluronic acid with nanoparticles that encapsulate curcumin and the second group was the one that encapsulates dexamethasone.</p>","PeriodicalId":39664,"journal":{"name":"Revista Espanola de Cirugia Ortopedica y Traumatologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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