{"title":"Mutation Screening of the CYP1B1 Gene Reveals Novel and Recurrent Pathogenic Variants in Pakistani Primary Congenital Glaucoma Patients","authors":"","doi":"10.22442/jlumhs.2024.01116","DOIUrl":"https://doi.org/10.22442/jlumhs.2024.01116","url":null,"abstract":"","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"11 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140727906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Isokinetic Strength Parameters of Quadriceps in Athletes and Non-Athletes","authors":"","doi":"10.22442/jlumhs.2023.01048","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.01048","url":null,"abstract":"OBJECTIVE: To compare the quadriceps isokinetic strength parameters of athletes and non-athletes. METHODOLOGY: The cross-sectional study was conducted from July to December 2019 at the Pakistan Sports Board, Islamabad. The sample size was 81, selected through a non-probability convenience sampling technique and calculated by the Rao Soft tool. The 41 participants were in the athletes' group, and 40 were in the non-athletes' group. Individuals with a history of sprain, strain, or fracture in the lower limbs within the last six months were excluded. The self-structured questionnaire includes demographic data, waist-to-hip ratio, thigh circumference, peak torque values and agility t-test score. The isokinetic strength of the right lower limb (RLL) was measured via Biodex system Pro 3. Data was analyzed through SPSS 22, and an independent t-test was applied for analysis between groups. Pearson test was used for the correlation coefficient. RESULTS: Athletes had significantly higher quadriceps muscle strength than non-athletes (p<0.001), indicating the positive impact of regular sports participation and physical training. Quadriceps peak torque positively correlated with thigh circumference (r=0.60, p<0.001), consistent with previous studies. Surprisingly, athletes exhibited a weak to moderate negative correlation between quadriceps peak torque and agility (r=-0.35, p<0.05), suggesting a potential trade-off between muscle mass and agility performance. Increased muscle bulk may compromise speed and flexibility. CONCLUSION: Athletes demonstrated superior quadriceps muscle strength, emphasizing the positive influence of sports involvement and physical training; thigh circumference positively correlated with Quadriceps peak torque, and Agility negatively correlated with quadriceps peak torque. KEYWORDS: Athletes and Non-athletes, Correlation, Isokinetic, Peak torque","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"15 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138597185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neurological Problems during Hajj Season: Review","authors":"","doi":"10.22442/jlumhs.2023.01015","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.01015","url":null,"abstract":"Worldwide gatherings at religious festivals raise the possibility of disease transmission among attendees and the local populace. The enormous gathering of pilgrims may impact the country's health system.Infectious diseases with epidemic characteristics threaten global health security, demonstrating the significance of preparedness for any public health catastrophe. This literature review describes the extensive neurological diseases related to hajj pilgrims and the importance of preventive methods to control these diseases. Our systematic review was conducted from many sources, including credible websites and journals. We found about 23 articles about the most common neurological disease in hajj pilgrims. A clear result was observed about increased incidents of meningitis as a global health neurological disease related to hajj pilgrims of total PubMed indexed publications studies, and one review article was done in 2019. This review study summarizes the neurological health challenge from infectious, non-infectious to stroke mimics presentation and the heatstroke prevalence in Hajj and the process of how the body adaption to heat stress may influence the body systems and brain function to be reported the most common presentation may mimic to a neurological cause. KEYWORDS: Religious Festivals, Neuro-infectious, Stroke, Heatstroke, Hajj, Makkah","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139197540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Number of Prenatal Visits on Breastfeeding Practices","authors":"","doi":"10.22442/jlumhs.2023.01030","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.01030","url":null,"abstract":"OBJECTIVE: To determine the impact of several prenatal visits on breastfeeding practices during the first six months of infant life. METHODOLOGY: This prospective cohort study was conducted in Darulsehat Hospital Karachi from August 2021 to August 2022 among pregnant females (36-40 weeks of gestation) regardless of their parity. Multiple pregnancy, intrauterine fetal death and medical disorders were excluded. A Convenient Non-probability sampling technique is used for the selection of participants. Participants were divided into three groups according to their number of prenatal visits. <4, 4-8, >8 and followed three times after childbirth to assess their breastfeeding practices. The first follow-up was done within 48 hours of delivery, the second at three months, and the third after six months of delivery. Each visit is assessed for three breastfeeding practices: exclusive, mixed, or bottle feeding. SPSS version 23 was used for analysis. RESULTS: Two hundred ten participants were interviewed. 78.6% were well-informed about breastfeeding during antenatal visits. Mean antenatal clinic visits of studied samples were 6 (6 - 8).7.1% were found with less than four antenatal visits, 68.1% with 4-8 visits, and only 24.8% had more than eight antenatal clinic visits. The percentage of exclusive feeding is highest in group 3 (>8 visits) i,e; 52.3%, followed by 43% in 4-8 visits and lowest at 4.7% in < 4 antenatal clinic visits samples. CONCLUSION: A more significant number of antenatal visits favorably influence BF practices regarding the commencement and continuation of breastfeeding. KEYWORDS: Prenatal visits, antenatal care, breastfeeding practices, lactation, exclusive breastfeeding, frequency of ANC","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139246540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Online Neurobiology Course - An Emergent Plan during the Pandemic","authors":"","doi":"10.22442/jlumhs.2023.01026","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.01026","url":null,"abstract":"OBJECTIVE: To obtain student's perceptions of the online neurobiology course conducted during the pandemic. METHODOLOGY: A cross-sectional survey was conducted among the MD3 (year 4) students. One hundred thirty-three students enrolled in the neurobiology course submitted their responses to the survey. The survey was administered as a questionnaire on a five-point Likert scale to record the student's perception of the different aspects of the course. Descriptive and Chi-square analyses were employed among the variables. Data was statistically analyzed using IBM SPSS version 22. Descriptive analysis was used to analyze students' perceptions of how the online course was administered. The Shapiro-Wilk normality test results for all survey items (p=0.000) indicate that participant responses were not normally distributed. Chi-square (Inferential statistical procedures) were employed to test hypotheses exploring associations among variables. RESULTS: The feedback analysis reflected that the students reacted positively to the modified teaching interventions and assessments. Most of the students were satisfied with the mode of delivery of the course and rated the course highly. CONCLUSION: The survey results indicated that the online neurobiology course successfully addressed the course learning outcomes. Lessons from these experiences and taking advantage of educational technologies can help design technology-aided blended learning courses to enhance teaching in the upcoming academic years. KEYWORDS: Neurobiology, pandemic, online, course, assessments, neuroanatomy","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"55 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139262561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound Findings in Adult Patients with Chronic Shoulder Pain Having No History of Trauma","authors":"Madiha Imtiaz","doi":"10.22442/jlumhs.2023.01035","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.01035","url":null,"abstract":"OBJECTIVE: To evaluate the frequency of non-traumatic chronic shoulder pain sonographically in the local population. METHODOLOGY: This cross-sectional study was conducted at the Department of Radiology, Combined Military Hospital Malir, from March to October 2020. A history of shoulder pain of more than one month duration was included. Patients with a History of shoulder dislocation, neurological, renal, hepatic and cardiac diseases were excluded. The sample size was 196. A non-probability consecutive sampling technique was employed. SPSS version 23 was used for statistical analysis. RESULTS: 196 patients (69.9% males and 30.1% females) with non-traumatic shoulder pain (56.4 % right side and 43.4% left) were scanned. The mean age was 42.80±11.20 years. Out of 196, 118(60.2%) were having complaints in dominant limbs (right 51.0% and left 9.2%); 78(39.8%) were having pain in non-dominant limbs (right 6.6% and left 33.2%). Significant findings were supraspinatus partial tear (46.9%), sub-acromial sub-deltoid bursitis(8.2%), and biceps tenosynovitis(6.1%), adhesive capsulitis, a complete tear of supraspinatus tendon, impingement syndrome, joint effusion, subscapularis tendon tear and tenosynovitis. 44(22.4%) patients had two pathologies, and 31 (15.8%) patients had three pathologies, respectively. Significant co-existent findings were biceps tenosynovitis (13.8%), Impingement syndrome (9.2%), bursitis (8.2%) and joint effusion (7.1%). Age and number of pathological were moderately positively correlated, r (194) = 0.46, p < 0.01 and keeping CI = 95%. CONCLUSION: Partial tears of the supraspinatus tendon were the most common pathology in non-traumatic shoulder myalgia, diagnosed on ultrasound, followed by sub-acromial sub-deltoid bursitis and biceps tenosynovitis, having moderate linear relation with age. KEYWORDS: Shoulder pain, Impingement syndrome, Rotator Cuff Tears, Tenosynovitis, Ultrasound Shoulder","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"112 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139267072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Thrombocytopenia and C-reactive protein in COVID-19 Patients Attending a Tertiary Care Hospital","authors":"","doi":"10.22442/jlumhs.2023.01038","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.01038","url":null,"abstract":"OBJECTIVE: This study evaluates the frequency and relationship between Thrombocytopenia and CRP levels in Covid-19 patients. METHODOLOGY: The cross-sectional retrospective study was conducted at Dr. Ishrat ul Ebad Khan's Institute of Blood Diseases from October 2021 to September 2022. Data was collected from existing data from the blood bank and hematology laboratory. C reactive protein (CRP) and complete blood count (CBC) levels were observed in Covid-19 patients. Both genders, all age groups, COVID-19 patients and patients having Thrombocytopenia and raised levels of CRP were included in this study. At the same time, other bone marrow transplant patients and other infectious diseases such as Hepatitis B, Hepatitis C, Dengue, and Malaria were excluded from this study. Statistical analysis was done by using the SPSS 20.0 version. RESULTS: Out of 844 patients, the mean age was 50 years, and the male proportion was high at 70% (n=590). Most patients, 95% (n=803) had grade 1 thrombocytopenia. The mean age was found to be higher (>50 years) in Grades 1 and 2 as compared to Grades 3 and 4, where we found (<40 years). A significant (p=0.002) mean age difference among grades was found. No significant (p=0.749) median difference in CRP among Grades were found. CONCLUSION: The current study shows that COVID-19 significantly increases C-reactive protein levels. While treating and managing the patients of COVID-19, it is essential to detect the biomarkers that can predict the severity and prognosis of this disease. KEYWORDS: Thrombocytopenia, Bleeding, C-reactive Protein, COVID-19","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139287938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Glutathione and Oxidized Low-Density Lipoprotein as Biomarkers of Oxidative Stress in Essential Hypertension","authors":"","doi":"10.22442/jlumhs.2023.00994","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.00994","url":null,"abstract":"","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"28 12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127635695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Motor imagery promising technique for Rehabilitation of Patients with Parkinson's disease: A Systematic Review","authors":"","doi":"10.22442/jlumhs.2023.01014","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.01014","url":null,"abstract":"","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116608045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medicinal Properties of Illicium Verum Hook. F.","authors":"","doi":"10.22442/jlumhs.2023.00962","DOIUrl":"https://doi.org/10.22442/jlumhs.2023.00962","url":null,"abstract":"","PeriodicalId":393911,"journal":{"name":"Journal of Liaquat University of Medical & Health Sciences","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124718357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}