Malaysian Journal of Analytical Sciences最新文献_第5页

WATER EXTRACT OF ONION PEEL ASH: AN EFFICIENT GREEN CATALYTIC SYSTEM FOR THE SYNTHESIS OF ISOINDOLINE-1,3-DIONE DERIVATIVES 洋葱皮灰水提物:合成异吲哚-1,3-二酮衍生物的高效绿色催化体系

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2301-03

Malaysian Journal, P. W. Chia, P. Chee, Mohd Zohirul Haziq Aziz, Siti Fairuz Mohd Radzi, Su-Yin Kan

{"title":"WATER EXTRACT OF ONION PEEL ASH: AN EFFICIENT GREEN CATALYTIC SYSTEM FOR THE SYNTHESIS OF ISOINDOLINE-1,3-DIONE DERIVATIVES","authors":"Malaysian Journal, P. W. Chia, P. Chee, Mohd Zohirul Haziq Aziz, Siti Fairuz Mohd Radzi, Su-Yin Kan","doi":"10.17576/mjas-2019-2301-03","DOIUrl":"https://doi.org/10.17576/mjas-2019-2301-03","url":null,"abstract":"Isoindoline-1,3-dione derivatives are important organic compounds associated with various interesting applications such as in the fields of material science, medicine, important building blocks and so on. Traditionally, the synthesis of isoindoline-1,3-dione derivatives are achieved using harmful and toxic catalysts, such as concentrated sulphuric acid, triphenylphosphine, ionic liquid [bmim][BF4] or phthalimide-N-sulfonic acid. Thus, the development of a greener catalytic system for the synthesis of isoindoline-1,3-dione derivatives is highly sought after. In this work, an efficient synthesis of isoindoline-1,3-dione derivatives using the Water Extract of Onion Peel Ash (WEOPA) method is described. The new approach provides several advantages including the non-usage of external acids, recyclable catalytic system, cheap and the yield of the synthesized products were obtained in moderate to good yields by reacting various anilines with phthalic anhydride. The current improved method is scientifically important, due to it avoid the use of environmental harmful reagents and at the same time provides an alternative method for bio-waste management.","PeriodicalId":39007,"journal":{"name":"Malaysian Journal of Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67646774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

DEHYDRATING ETHANOL USING A TERNARY SOLUTE AND EXTRACTIVE BATCH DISTILLATION 用三元溶质和萃取间歇精馏脱水乙醇

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2301-15

Malaysian Journal, Pengeringan Etanol, Menggunakan Zat Larut, Ternari dan Penyulingan, Kelompok Hasil Ekstrak, T. Marnoto, Chintya Rizki Hapsari, Angga Y. Prakosa

{"title":"DEHYDRATING ETHANOL USING A TERNARY SOLUTE AND EXTRACTIVE BATCH DISTILLATION","authors":"Malaysian Journal, Pengeringan Etanol, Menggunakan Zat Larut, Ternari dan Penyulingan, Kelompok Hasil Ekstrak, T. Marnoto, Chintya Rizki Hapsari, Angga Y. Prakosa","doi":"10.17576/mjas-2019-2301-15","DOIUrl":"https://doi.org/10.17576/mjas-2019-2301-15","url":null,"abstract":"Anhydrous bioethanol is a material used in many applications including biofuel. Commonly, bioethanol is produced through sugar fermentation which results in a low concentration of ethanol. For utilization as biofuel, the lowest ethanol concentration should be 99.5%. Distillation is common technique to dry a mixture solution, however, the mixture of bioethanol and water is forming an azeotrope that limit the concentration of 96% ethanol. This paper discusses ethanol dehydration through extractive batch distillation by the addition of a ternary solute sodium hydroxide, citric acid, sulfuric acid, glycerol or ethylene glycol to ethanol. The initial concentration of ethanol used was 86% v/v, and the amount of ternary solute added was selected based on the colligative properties of the solution, which included a boiling point elevation (ΔTB) that ranged from 5 to 25 °C. All the ternary solutes could break or shift the ethanol-water azeotrope. The highest concentration of ethanol was 99.91% v/v at ΔTB = 25 °C with sulfuric acid as the ternary component. The resulted ethanol concentration exhibited a linear relationship with ΔTB, which was also affected by the boiling point of the ternary solute. This study successfully produced anhydrous bioethanol by low cost and simple distillation process.","PeriodicalId":39007,"journal":{"name":"Malaysian Journal of Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67647335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

RAPID SPECTROPHOTOMETRIC METHOD FOR HISTAMINE DETERMINATION IN FISH USING ALIZARIN RED S AND METAL 用茜素红和金属分光光度法快速测定鱼中组胺

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2303-15

M. Jannatin, Ayu Nabila Izazi Latjuba, S. Wahyuni, G. Supriyanto, W. A. Ibrahim

{"title":"RAPID SPECTROPHOTOMETRIC METHOD FOR HISTAMINE DETERMINATION IN FISH USING ALIZARIN RED S AND METAL","authors":"M. Jannatin, Ayu Nabila Izazi Latjuba, S. Wahyuni, G. Supriyanto, W. A. Ibrahim","doi":"10.17576/mjas-2019-2303-15","DOIUrl":"https://doi.org/10.17576/mjas-2019-2303-15","url":null,"abstract":"An analytical method for the determination of histamine using metals and alizarin red S (ARS) reagents by UV-Visible spectrophotometry was developed. Cu(II), Co(II) and ARS were used to form colored complex with histamine. The developed method was used to detect qualitatively and quantitatively the presence of histamine. Absorbance of Cu(II) and Co(II) complex were measured at a maximum wavelength of 505.5 and 567 nm, respectively. Optimization of analytical parameters such as concentration of metals, concentration of ARS, sample solution pH, and optimum time for complex formation were performed. Experimental results showed that the optimum concentration of Cu(II) was 50 ppm, 75 ppm ARS, sample solution pH 6, and 15 minutes optimum time, while the optimum concentration of Co(II) was 125 ppm, ARS was 75 and 50 ppm, sample solution pH 5 and 10 minutes optimum time. Method validation indicated that the coefficient of variation, limit of detection (LOD) (S/N =3), and limit of quantitation (LOQ = 10S/N) of Cu(II) were 0.65%, 8.94 ppm, and 29.82 ppm respectively with a sensitivity of 0.0054 ppm and linearity of 0.9959. Accuracy of histamine determination through Cu-ARS-histamine complex at a concentration of 50, 100, and 150 ppm were 105.7% (RSD = 0.777%, n = 3), 105.06% (RSD = 0.606%, n = 3), and 94.12% (RSD = 0.767%, n = 3), respectively. Meanwhile, the CV, LOD, and LOQ of Co(II) were 0.28%; 2.58 ppm; and 8.6 ppm respectively with a sensitivity of 0.0006 ppm and linearity of 0.9965. Accuracy of histamine determination through Co-ARS-histamine complex at a concentration of 50, 75, and 125 ppm were 98.33%, 95.83%, 93.88%, respectively. The proposed method was successfully applied to the determination of histamine in a fish sample with quantitative recovery; for Cu(II) complex (99.23%) and Co(II) complex (102.62%).","PeriodicalId":39007,"journal":{"name":"Malaysian Journal of Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67647279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SYNTHESIS AND MOLECULAR DOCKING OF 2,4,5-TRISUBSTITUTED-1,3-THIAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS 2,4,5-三取代-1,3-噻唑类抗菌衍生物的合成与分子对接

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2302-08

I. H. A. Ripain, N. Roslan, Nurul Shazana Norshahimi, S. M. Salleh, Noraslinda M. Bunnori, N. Ngah

{"title":"SYNTHESIS AND MOLECULAR DOCKING OF 2,4,5-TRISUBSTITUTED-1,3-THIAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS","authors":"I. H. A. Ripain, N. Roslan, Nurul Shazana Norshahimi, S. M. Salleh, Noraslinda M. Bunnori, N. Ngah","doi":"10.17576/mjas-2019-2302-08","DOIUrl":"https://doi.org/10.17576/mjas-2019-2302-08","url":null,"abstract":"The emergence of antibiotic resistance against bacterial strains has attracted great interest in the discovery and development of new antibacterial agents. Thiazole derivatives have been widely used in the biological as well as pharmacological fields and their efficiency as pharmaceutical drugs are well established. In this study, a series of thiazole derivatives were synthesized in reaction between 3-chloroacetyl acetone and ammonium thiocyanate followed by incorporating selected primary amines in one-pot synthesis manner. The compounds were structurally characterized by FTIR, 1H NMR, UV-Vis and GC-MS. Their antibacterial properties were screened using disc diffusion technique against Gram positive (B. cereus and S. epidermidis) as well as Gram negative (E.coli and P. aeruginosa) bacterial strains. The compound of T3 exhibited the most potent antibacterial activity. Molecular docking studies were also performed against Glucosamine-6-phosphate (GlcN-6-P) synthase which is known as the essential building block of most bacteria. According to the docking result, T3 exhibited the minimum binding energy of -7.09 kcal mol-1 as compared to T1 and T2 with -6.49 and 6.76 kcal mol-1,respectively which is in agreement with antibacterial result. The output of this preliminary study will contribute in structural enhancement in drug discovery.","PeriodicalId":39007,"journal":{"name":"Malaysian Journal of Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67647501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

OPTIMIZATION OF HYDROGEN PRODUCTION FROM FRUIT WASTE THROUGH MESOPHILIC AND THERMOPHILIC DARK FERMENTATION: EFFECT OF SUBSTRATE-TO-INOCULUM RATIO 通过中温和嗜热暗发酵优化水果废弃物产氢:底物与接种物比的影响

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2301-14

K. Cahyari, M. Hidayat, S. Syamsiah, Sarto

引用次数: 9

RESISTANCE OF NATIVE BACTERIA ISOLATED FROM ACTIVATED SLUDGE TOWARDS IRON AND MANGANESE 活性污泥中分离的原生细菌对铁和锰的抗性

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2301-16

Malaysian Journal, Ketahanan Pencilan Bakteria, Asli daripada Enapcemar Teraktif, T. Mangan, Nuratiqah Marsidi, M. Halmi, S. R. Abdullah

引用次数: 1

LASER-ASSISTED SILICON ETCHING FOR MICRO FUEL CELL ELECTRODE PLATE FABRICATION 激光辅助硅蚀刻微燃料电池极板制造

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2302-18

Azmah Hasran, S. Kamarudin, B. Majlis, W. Daud, A. Kadhum, G. Sugandi

{"title":"LASER-ASSISTED SILICON ETCHING FOR MICRO FUEL CELL ELECTRODE PLATE FABRICATION","authors":"Azmah Hasran, S. Kamarudin, B. Majlis, W. Daud, A. Kadhum, G. Sugandi","doi":"10.17576/mjas-2019-2302-18","DOIUrl":"https://doi.org/10.17576/mjas-2019-2302-18","url":null,"abstract":"Silicon electrode plates for micro fuel cells were obtained using a microfabrication process based on the micro-electromechanical system (MEMS) technology. The dry etching process involved the laser ablation technique using the highly stable Nd:YAG. This technique is suitable for micromachining silicon substrates. The total size of the electrode plate was 2.5 cm x 2.5 cm and the active reaction area was 1 cm. An increase in laser scan numbers deepened the groove being etched on the silicon sample, but it showed a saturated behavior as the number of scans became higher. The time required to etch a complete electrode plate flow field with 14 square-shaped through-holes of 0.185 cm x 0.185 cm area using laser ablation was ~30 minutes, which was much shorter than the wet etching time of more than 10 hours with the potassium hydroxide solution (KOH) solution. The laser-etched flow field achieved vertical sidewalls as per the original design, whereas the wet-etched structure achieved a typical anisotropic hole structure with sidewalls that were approximately 54o to the electrode surface due to the <100> orientation of the silicon wafer. Therefore, the laser ablation technique was chosen to produce the electrode plates for the micro fuel cell as it can save time on the etching process and produce more precise flow field dimensions for the electrode plates with less process steps compared with the conventional wet etching processes using KOH solution.","PeriodicalId":39007,"journal":{"name":"Malaysian Journal of Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67647542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PRODUCTION OF TITANIUM DIOXIDE NANOFIBER (TNF): INFLUENCE OF ELECTROSPINNING PARAMETER ON CRYSTALLINE SIZE 二氧化钛纳米纤维的制备:静电纺丝参数对结晶尺寸的影响

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2301-05

N. Abdullah, S. Kamarudin, L. Shyuan

引用次数: 0

ESTERIFICATION OF ACETIC ACID AND BENZYL ALCOHOL OVER ZEOLITE HX PRODUCED FROM BANGKA BELITUNG KAOLIN 以邦卡别里洞高岭土为原料制备的沸石上醋酸和甲醇的酯化反应

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2303-17

Vita Nur Iftitahiyah, D. Prasetyoko, Hartati, Y. Ni'mah, H. Bahruji, Hadi Nur

引用次数: 1

EFFECT OF DEPOSITION TIME ON STRUCTURAL AND CATALYTIC PROPERTIES OF Pt FILMS ELECTRODEPOSITED ON Ti SUBSTRATE 沉积时间对钛基电沉积Pt薄膜结构和催化性能的影响

Malaysian Journal of Analytical Sciences Pub Date : 2019-01-01 DOI: 10.17576/mjas-2019-2301-07

S. Malek, Y. Mohd

{"title":"EFFECT OF DEPOSITION TIME ON STRUCTURAL AND CATALYTIC PROPERTIES OF Pt FILMS ELECTRODEPOSITED ON Ti SUBSTRATE","authors":"S. Malek, Y. Mohd","doi":"10.17576/mjas-2019-2301-07","DOIUrl":"https://doi.org/10.17576/mjas-2019-2301-07","url":null,"abstract":"Platinum (Pt) films were prepared on Titanium (Ti) surface at various deposition times ranging from 30 to 90 minutes using the electrodeposition technique. The morphology of the Pt films was determined using field emission scanning electron microscope (FESEM). Furthermore, the electrocatalytic activity of the prepared Pt films towards methanol oxidation in alkaline medium was investigated using cyclic voltammetry. The surface morphology changed with different deposition times from less compact durian-like structure at shorter times (< 60 minutes) to more compact durian-like structure at longer times (> 60 minutes). The loading amount and surface coverage of Pt on the Ti surface were increased as the deposition time increased. The calculated values of electrochemically active surface area (ECSA) for the Pt films were increased with increasing deposition time as evident in 30 minutes (6.54 m g), 45 minutes (7.34 m g) and 60 minutes (8.08 m g). Nevertheless, the ECSA value dropped to 7.70 m g for longer deposition time (90 minutes). This may be caused by the coagulation of the Pt centres with the growth of neighbouring centres, which decreasing the available active surface area on the films. This film also demonstrated the highest stability for methanol oxidation reaction (MOR) in alkaline medium with the result of 5.18 mA cm at 1 hour.","PeriodicalId":39007,"journal":{"name":"Malaysian Journal of Analytical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67646977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0