International Journal Bioautomation最新文献_第2页

Arrhythmia Classification Based on Adaptive Refined Composite Multiscale Fluctuation Dispersion Entropy 基于自适应精细复合多尺度波动色散熵的心律失常分类

International Journal Bioautomation Pub Date : 2023-09-01 DOI: 10.7546/ijba.2023.27.3.000895

Changsheng Zhang, Xin Ding, Changping Tian, Wei Peng

{"title":"Arrhythmia Classification Based on Adaptive Refined Composite Multiscale Fluctuation Dispersion Entropy","authors":"Changsheng Zhang, Xin Ding, Changping Tian, Wei Peng","doi":"10.7546/ijba.2023.27.3.000895","DOIUrl":"https://doi.org/10.7546/ijba.2023.27.3.000895","url":null,"abstract":"To improve the accuracy of electrocardiography (ECG) signal classification and identify abnormal heart rhythms, an arrhythmia classification algorithm based on adaptive refined composite multiscale fluctuation dispersion entropy (ARCMFDE) is proposed. First, an improved QRS complex detection algorithm named the improved Pan-Tompkins algorithm (IPTA) is used. The QRS wave is detected, and the waveform is further processed; then, the signal is decomposed into multiple modal components using variational mode decomposition with the optimized number of decomposition layers (K). Subsequently, the RCMFDE is extracted from the different modal components as a classification feature. Finally, differential evolution (DE) and grey wolf optimization (GWO) are combined to form the hybrid differential evolution-grey wolf pack optimization (DE-GWO) algorithm to optimize the penalty factor c and the kernel function parameter g of the support vector machine for performing pattern recognition. Experimental results show that compared with other methods such as variational mode decomposition (VMD), fluctuation dispersion entropy (FDE), genetic algorithms (GA), and support vector machine (SVM). The proposed classification model has superior performance, with an average accuracy of 96.1%, a sensitivity of 95.9%, and a specificity of 98.7% for four types of heart rhythm recognition. Thus, accurate classification of ECG signals can be achieved using the proposed ARCMFDE-based DE-GWO method.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135589083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Queuing Theory to Analysis of Waiting Time in the Hospital 排队论在医院候诊时间分析中的应用

International Journal Bioautomation Pub Date : 2023-09-01 DOI: 10.7546/ijba.2023.27.3.000904

Manish Kumar Pandey, Dharmendra Kumar Gangeshwer

引用次数: 0

Adaptive Fed-batch Control of Escherichia coli Fermentation for Protein Production 大肠杆菌蛋白发酵的自适应补料批量控制

International Journal Bioautomation Pub Date : 2023-09-01 DOI: 10.7546/ijba.2023.27.3.000930

Velislava Lyubenova, Anastasiya Zlatkova, Maya Ignatova

引用次数: 0

Rare Allele 29 at Locus D2S1338 Observed During Routine Casework in Bulgarian Population 保加利亚人群常规病例调查中发现D2S1338位点罕见等位基因29

International Journal Bioautomation Pub Date : 2023-06-01 DOI: 10.7546/ijba.2023.27.2.000900

P. Iliev, V. Djeliova, E. Angelova, Bogdan Mirchev, Atanas Hristov, M. Mileva, M. Georgieva, Kamen Peev, N. Krastev, Dimo Krastev Krastev, Аleksandar Apostolov

{"title":"Rare Allele 29 at Locus D2S1338 Observed During Routine Casework in Bulgarian Population","authors":"P. Iliev, V. Djeliova, E. Angelova, Bogdan Mirchev, Atanas Hristov, M. Mileva, M. Georgieva, Kamen Peev, N. Krastev, Dimo Krastev Krastev, Аleksandar Apostolov","doi":"10.7546/ijba.2023.27.2.000900","DOIUrl":"https://doi.org/10.7546/ijba.2023.27.2.000900","url":null,"abstract":"In this work, we report a rare allele 29 at locus D2S1338, established during routine forensic practice in a case of first-degree kinship (parenthood). This rare allele variant 29 at locus D2S1338, to the best of our knowledge, is reported for the first time for the Bulgarian population. So far it has not been registered in studies of allele frequencies in the same locus for 20 population groups in Europe and Asia. The presentation of similar genotyping findings relating to rare/unexpected population genetic variation is very important for the examination and documentation of such anomalies. The analysis has been performed for 16 STR loci: D2S1338, SE33, D16S539, D18S51, TH01, D12S391, D3S1358, FGA, vWA, D21S11, D1S1656, D2S441, D8S1179, D19S433, D22S1045, D10S1248 and 2 sex determination systems – Amelogenin and Y indel, set in NGM DetectTM PCR Amplification Kit (Applied Biosystems). The use of allelic witnesses in the diagnostic practice is mandatory in the standard fragment DNA analysis. The allelic witness contains well-known preset alleles for the examined locus. Establishing alleles that are outside the factory preset is of importance for broadening the scope of the witness and heightening the accuracy of the analysis. Rare allelic variants significantly increase the strength of discrimination when DNA profiles are compared. In this regard, it is important to report any new information about the emergence of rare allele variants detected in a particular population group.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44434703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Analysis of the “Horizontal Y” Shaped Queuing Model to Assist in Health Care Institution 医疗机构“水平Y”型排队模型的辅助分析

International Journal Bioautomation Pub Date : 2023-06-01 DOI: 10.7546/ijba.2023.27.2.000903

M. Pandey, D. K. Gangeshwer

引用次数: 0

Assessment of the Factors Influencing the Survival of the Ventricular Shunt in Infantile Hydrocephalus 影响小儿脑积水脑室分流存活因素的评估

International Journal Bioautomation Pub Date : 2023-06-01 DOI: 10.7546/ijba.2023.27.2.000926

L. Todorova, J. Surchev, Alexander Marazov

{"title":"Assessment of the Factors Influencing the Survival of the Ventricular Shunt in Infantile Hydrocephalus","authors":"L. Todorova, J. Surchev, Alexander Marazov","doi":"10.7546/ijba.2023.27.2.000926","DOIUrl":"https://doi.org/10.7546/ijba.2023.27.2.000926","url":null,"abstract":"The purpose of the present research is to perform a retrospective analysis of 242 ventricular shunts implanted in childhood due to infantile hydrocephalus, submitted to a long-term follow-up (27.84 ± 6.13 years) and investigate the factors influencing the survival of the shunt, applying modern mathematical approaches. The contingent consists of 242 patients who were shunted due to infantile hydrocephalus in childhood, 55% of whom were under 6 months old when the shunt was implanted. For the entire follow-up period, patients underwent 375 revisions (average 1.55 revisions per shunt), 38% are without shunt failure, with only one revision – 26%, with two – 14%. The remaining 22% have 3 or more revisions (4.58 shunt revisions) and they make 65% of all revisions. 68.5% of all revisions are due to mechanical complications; to functional (inadequate drainage) – 7.5%. 9.1% of the patients had inflammatory complications. We found that the age at shunting (under 3 months – the worst trend) and the interval to the first revision (over 6 months – a smaller number of revisions) are of the biggest importance for the number of the following revisions. If the patient survives one year after shunting without failure, the risk of such is under 50% during the whole shunt existence.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46833061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detailed Investigation of Knee Biomechanics during Posture Maintenance while Applying Different Static Loadings on the Spine 对脊柱施加不同静载荷维持姿势过程中膝关节生物力学的详细研究

International Journal Bioautomation Pub Date : 2023-06-01 DOI: 10.7546/ijba.2023.27.2.000946

R. Raikova, I. Ivanov, Oleg Hristov, Nikol Markova, L. Trenev, S. Angelova

{"title":"Detailed Investigation of Knee Biomechanics during Posture Maintenance while Applying Different Static Loadings on the Spine","authors":"R. Raikova, I. Ivanov, Oleg Hristov, Nikol Markova, L. Trenev, S. Angelova","doi":"10.7546/ijba.2023.27.2.000946","DOIUrl":"https://doi.org/10.7546/ijba.2023.27.2.000946","url":null,"abstract":"The aim of this paper was to investigate in detail the biomechanics of the knee during different static loadings on the spine using electromyographic (EMG) signals from six main surface muscles acting in the knee joint; three components of the ground reaction force measured by a force plate; knee flexion joint angle measured by a flexible goniometer; and the distances between the bones (femur and tibia) forming the knee joint measured by an echograph. The measurements were taken without weight (reference straight position) and with a weight of 2, 5, 10, 15, 17, and 20 kg placed in a rucksack on the spine. The results showed that the forces in the horizontal and sagittal planes were negligible, and the reaction in the frontal plane increased and was linearly dependent on the carrying weight. The distance between bones decreased linearly with increasing weight for all participants from 3.94% to 53.92% from the referent position. The knee angle varied and in many cases decreased with increasing weight. The calculated correlation coefficients between mean EMG signals and loading weight showed that the adjustment of different subjects’ musculature to increasing load is individual. In general, knee joint balance is a dynamic individual process.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44018402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Comparison of Calcified Plaque Volume in Coronary Arteries using Filtered Back Projection and Intelli IP Advanced at CT-scan 128 Slice 冠状动脉钙化斑块体积的筛选后投影与Intelli IP - Advanced在128层ct扫描中的比较

International Journal Bioautomation Pub Date : 2023-03-01 DOI: 10.7546/ijba.2023.27.1.000878

Naufal Arya Pratama, L. Muqmiroh, Amillia Kartika Sari, Widiana Ferriastuti, Falentina Syivasari, Muhaimin, Sidarta Prassetyo, Cong Tien Nguyen, Phan Anh Phuong, V. Luu

{"title":"Comparison of Calcified Plaque Volume in Coronary Arteries using Filtered Back Projection and Intelli IP Advanced at CT-scan 128 Slice","authors":"Naufal Arya Pratama, L. Muqmiroh, Amillia Kartika Sari, Widiana Ferriastuti, Falentina Syivasari, Muhaimin, Sidarta Prassetyo, Cong Tien Nguyen, Phan Anh Phuong, V. Luu","doi":"10.7546/ijba.2023.27.1.000878","DOIUrl":"https://doi.org/10.7546/ijba.2023.27.1.000878","url":null,"abstract":"Calcified plaque has a major effect on increasing plaque volume which can increase the risk of Coronary Artery Disease (CAD). The use of Filtered Back Projection (FBP) on CT-scans still has flaws in terms of image quality that can result in errors in the calculation of plaque volume. Intelli IP Advanced is hitachi CT-scan’s Iterative Reconstruction (IR) type and can improve image quality compared to FBP. The purpose of this study is to find out the comparison of calcified plaque volume in coronary arteries using FBP and Intelli IP Advanced. This study used 38 samples of coronary artery blood vessels that had calcified plaque and reconstructed using the reconstruction of FBP and Intelli IP Advanced algorithms (Levels 1-3). Plaque calculation is done automatically using aquarius intuition edition application on CT-scan Hitachi SCENARIA 128 Slice. The results in this study found significant differences (p < 0.05) in calcified plaque volume results with the use of FBP and Intelli IP Advanced algorithm reconstruction (Levels 1-3). However, significant differences are found only in algorithm reconstruction pairs (Intelli IP Advanced Level 1 and Level 3) that have a p < 0.05. The conclusion is that IR affects the volume value of calcified plaque.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42340491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photobiomodulation Effect of 850 nm Near-infrared Diode Laser on the Release of M1-related Cytokines Inmonocytic THP-1 Cells 850 nm近红外二极管激光对THP-1单核细胞释放m1相关细胞因子的光生物调节作用

International Journal Bioautomation Pub Date : 2023-03-01 DOI: 10.7546/ijba.2023.27.1.000857

Ruwaidah A. Mussttaf, Mayyadah Hasan Rhaif Al-sahlanee, N. S. Dawood, David F L Jenkins, A. Jha

{"title":"Photobiomodulation Effect of 850 nm Near-infrared Diode Laser on the Release of M1-related Cytokines Inmonocytic THP-1 Cells","authors":"Ruwaidah A. Mussttaf, Mayyadah Hasan Rhaif Al-sahlanee, N. S. Dawood, David F L Jenkins, A. Jha","doi":"10.7546/ijba.2023.27.1.000857","DOIUrl":"https://doi.org/10.7546/ijba.2023.27.1.000857","url":null,"abstract":"Photobiomodulation (PBM) is a form of the use of visible red and Near-infrared (NIR) light at low power, where a laser light photon is absorbed at the electronic level, without heat production. PBM can be applied in wide range of treatment to help the wound, inflammation, edema, and pain reduction. However, there is a lack of scientific documentation regarding its actual effects. Objectives: This study assesses the impact of PBM on the release of M1-related cytokine in monocyte cells with particular emphasis on interleukin-1β (IL-1β) and Tumour Necrosis Factor α (TNF-α). Methods: Tamm-Horsfall Protein 1 (THP-1) macrophages M1 cells have been exposed to the light from the diode laser of 850nmat different doses (0, 0.6, 1.2 and 3.6 J/cm2). The release of cytokines was determined by enzyme-linked immunosorbent assay, after different periods of incubation (0, 12, 24, and 48 hours) post-irradiation. The proliferation of fibroblast cells suspended in irradiated M1-supernatent was evaluated for the same periods of incubation. Results: The results showed that PBM significantly enhanced M1-related cytokine release (p < 0.05). Obviously, IL-1β increased post-irradiation at 1.2 J/cm2 more than other doses for all incubation periods. TNF-α was decreased significantly after two days of irradiation (p < 0.005) for all doses. A significant increase in fibroblast proliferation (p < 0.005) was observed concomitant with the boost of cytokine release. Conclusion: This in vitro study has demonstrated that the PBM of the 850 nm diode laser therapy can enhance M1-related cytokine release, which in turn increases the proliferation of fibroblast cells. Moreover, PBM at 850 nm plays an anti-inflammatory role, which manifested by decreasing the level of TNF-α. Therefore, this therapy may be able to accelerate the wound healing process.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49123390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the Phototoxicity and Antitumor Activity of Plant Extracts from Tanacetum vulgare L., Epilobium parviflorum Schreb., and Geranium sanguineum L. 紫菀、小叶莲子提取物的光毒性及抗肿瘤活性研究。和天竺葵(Geranium sanguineum L.)。

International Journal Bioautomation Pub Date : 2023-03-01 DOI: 10.7546/ijba.2023.27.1.000888

Inna Sulikovska, E. Ivanova, Ivaylo K. Ivanov, D. Tasheva, M. Dimitrova, B. Nikolova, I. Iliev

{"title":"Study on the Phototoxicity and Antitumor Activity of Plant Extracts from Tanacetum vulgare L., Epilobium parviflorum Schreb., and Geranium sanguineum L.","authors":"Inna Sulikovska, E. Ivanova, Ivaylo K. Ivanov, D. Tasheva, M. Dimitrova, B. Nikolova, I. Iliev","doi":"10.7546/ijba.2023.27.1.000888","DOIUrl":"https://doi.org/10.7546/ijba.2023.27.1.000888","url":null,"abstract":"Our country is rich in medicinal plants with a thousand-year tradition of use for therapeutic and cosmetic purposes. World Health Organization estimates that around 70% of population is using traditional (folk) medicine to cure various ailments. In many cases, herbal preparations prove to be useful, but some of them can also exert toxic effects. Therefore, herbal extracts should be tested both as curatives and for safety application. The aim of the present work was to investigate extracts from Tanacetum vulgare (TVA), Epilobium parviflorum (EPE) and Geranium sanguineum (GSA), obtained by different organic solvents, for their phototoxicity and anticancer activity. The standard BALB/c 3T3 Neutral Red Uptake phototoxicity/cytotoxicity assay was used to evaluate the possible phototoxic properties of the extracts. The antitumor activity of the extracts was studied in vitro on a panel of human tumor cell lines in comparison to the non-tumorigenic MCF-10A cells. The selectivity indices and the photo-irritancy factors were determined. The results show that the studied extracts are not phototoxic at concentration range from 4 to 1000 µg/ml. Determined photo-irritancy factors (PIF) for the extracts was < 2 (PIF for EPE = 1.72, GSA = 1.04, TVA = 1.43), which assigns them to the category of non-phototoxic substances. In addition, at concentrations lower than < 60 µg/ml, no statistically significant cytotoxicity was observed. The selectivity index was calculated relative to the IC50 value for non-tumorigenic MCF-10A cells. The highest selective index obtained with respect to the HT-29 cells was shown by all testing extracts (selective index (SI) for EPE = 2.6, GSA = 2.4 and TVA = 2.5), to the HeLa cells by extract GSA (SI = 2.0) and to the PC3 cells by extracts GSA (SI = 2.6) and TVA (SI = 2.0). Presented data shows that the studied extracts have a high level of photosafety with a promising antitumor activity in certain cell lines.","PeriodicalId":38867,"journal":{"name":"International Journal Bioautomation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46629706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0