{"title":"Semiconductor lasers for bio-medical Raman spectroscopy","authors":"B. B. Praveen, P. Ashok, K. Dholakia","doi":"10.1049/PBHE007E_CH11","DOIUrl":"https://doi.org/10.1049/PBHE007E_CH11","url":null,"abstract":"During the 2000's and 2010's Raman spectroscopy has proved its potential to be used for chemical fingerprinting of biological materials. This has enabled this technique to be translated as a novel diagnostic tool for disease diagnosis with high sensitivity and specificity. Raman scattering, being a weak process, relies greatly on the power and spectral quality of the excitation source for its effectiveness. Advent of relatively high power, frequency stabilized semiconductor lasers which has relatively small form factor when compared to its gas laser counterparts enabled developing portable Raman systems for clinical diagnostics.","PeriodicalId":388607,"journal":{"name":"Semiconductor Lasers and Diode-based Light Sources for Biophotonics","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129073474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Near-infrared spectroscopy systems for biomedical applications","authors":"Shudong Jiang, B. Pogue","doi":"10.1049/PBHE007E_CH10","DOIUrl":"https://doi.org/10.1049/PBHE007E_CH10","url":null,"abstract":"Near infrared spectroscopy in both frequency domain and time domain has many biomedical applications: mainly brain measurements; monitoring tumour chemotherapy responses; diffuse optical spectroscopic tomography imaging; and pulse oximetry.","PeriodicalId":388607,"journal":{"name":"Semiconductor Lasers and Diode-based Light Sources for Biophotonics","volume":"1016 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134505284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. B. Jensen, A. Hansen, C. Pedersen, P. Andersen, P. Petersen
{"title":"Diode laser systems based on nonlinear frequency conversion","authors":"O. B. Jensen, A. Hansen, C. Pedersen, P. Andersen, P. Petersen","doi":"10.1049/PBHE007E_CH7","DOIUrl":"https://doi.org/10.1049/PBHE007E_CH7","url":null,"abstract":"In this chapter, we will give a short introduction to nonlinear frequency conversion with second-order nonlinear optics to provide the basic background to the topic and highlight the important parameters to consider when designing a light source based on frequency conversion. In the following section, the different commonly used implementations of nonlinear frequency conversion will be introduced and some examples of demonstrated laser sources will be given. Finally, we will provide an outlook for the development of frequency converted diode laser light sources and briefly discuss some of the applications.","PeriodicalId":388607,"journal":{"name":"Semiconductor Lasers and Diode-based Light Sources for Biophotonics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133062734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Semiconductor disk lasers","authors":"M. Guina, E. Kantola, T. Leinonen, A. Rantamäki","doi":"10.1049/PBHE007E_CH8","DOIUrl":"https://doi.org/10.1049/PBHE007E_CH8","url":null,"abstract":"Semiconductor disk lasers (SDLs), also known as optically pumped vertical external-cavity surface-emitting lasers (VECSELs), offer unparalleled features combining high beam quality, large wavelength coverage, multi-watt output power, narrow linewidth, and broad tuning range. Moreover, relative to the features they provide, SDLs are compact and cost-effective systems. Their unique properties have already been recognized in biophotonics, for example, in photocoagulation treatment of macular degeneration using yellow radiation and multiphoton imaging, yet their full spread to applications is still to come. This chapter provides an overview of key technology concepts related to SDLs and a summary of the most important developments in terms of wavelength coverage and output powers. Specific developments are presented for SDLs emitting continuous wave (CW) radiation at the yellow-orange-red optical spectrum and for SDLs emitting picosecond pulses at red wavelengths. The chapter is concluded with a review of several biophotonics applications and their needs for laser sources, which are then put in a perspective of current SDL achievements.","PeriodicalId":388607,"journal":{"name":"Semiconductor Lasers and Diode-based Light Sources for Biophotonics","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116352895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential biomedical use of diode-laser-induced luminescence from upconverting nanoparticles","authors":"Monirehalsadat Mousavi, S. Andersson-Engels","doi":"10.1049/PBHE007E_CH9","DOIUrl":"https://doi.org/10.1049/PBHE007E_CH9","url":null,"abstract":"The intention with this chapter is to briefly review the capabilities made possible in the field of biomedical diagnostics and treatment by employing upconverting nanoparticles (UCNPs), as well as the importance of appropriate light sources for such applications. The field of UCNPs in biomedicine has grown rapidly the last decade, since they first were made sufficiently small and bright to be of real interest for biomedical applications. This research has been reviewed previously, while this chapter will focus on recent advances in the use of UCNPs for preclinical applications and diagnostic assays using laser diode excitation.","PeriodicalId":388607,"journal":{"name":"Semiconductor Lasers and Diode-based Light Sources for Biophotonics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130673925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introduction to semiconductor light sources and their biomedical applications","authors":"P. Andersen, P. Petersen","doi":"10.1049/PBHE007E_CH1","DOIUrl":"https://doi.org/10.1049/PBHE007E_CH1","url":null,"abstract":"(03/10/2019) Introduction to semiconductor light sources and their biomedical applications The present chapter serves as a brief introduction to semiconductor light sources mainly laser diodes and light emitting diodes, and the basic physical properties of their semiconductor materials. The chapter also discusses the main reasons for semiconductor light sources being attractive for biomedical applications which range from patient diagnostics imaging to direct treatment such as using photodynamic therapy. It is expected that this specific application area will grow significantly in the future, and that it will be an increasingly important physical properties part of the semiconductor industry.","PeriodicalId":388607,"journal":{"name":"Semiconductor Lasers and Diode-based Light Sources for Biophotonics","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133119971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Q-switched and mode-locked lasers for biophotonic applications","authors":"E. Rafailov, E. Avrutin","doi":"10.1049/PBHE007E_CH3","DOIUrl":"https://doi.org/10.1049/PBHE007E_CH3","url":null,"abstract":"We have attempted an overview of fast-pulsating lasers (gain-switched, Q-switched and mode-locked) in various biomedical applications. By necessity, the accents in the chapter have been to an extent coloured by our research experience and interests; apologies are extended to those authors whose work may have been omitted. Different properties of a laser system are important for different applications (e.g., high instantaneous and average power for multiphoton spectroscopy vs. spectral tuning range for OCT), but all the designs above benefit from the properties of semiconductor lasers such as chip compactness, ease of pumping, and high gain per unit length. The use of nanostructures, particularly QDs, has been shown to open new exciting opportunities.","PeriodicalId":388607,"journal":{"name":"Semiconductor Lasers and Diode-based Light Sources for Biophotonics","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127752285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}