Pediatric Cardiac Surgery Annual最新文献_第7页

Replacement of the Mitral Valve Under One Year of Age: Size Matters 一岁以下的二尖瓣置换术:大小问题

Pediatric Cardiac Surgery Annual Pub Date : 2021-01-01 DOI: 10.1053/j.pcsu.2021.03.006

Federica Caldaroni MD , Christian P. Brizard MD , Yves d'Udekem MD, PhD

引用次数: 3

The Ross Procedure in Children: The Gold Standard? 儿童罗斯手术:黄金标准?

Pediatric Cardiac Surgery Annual Pub Date : 2021-01-01 DOI: 10.1053/j.pcsu.2021.03.002

Luke M. Wiggins MD , S. Ram Kumar MD, PhD , Vaughn A. Starnes MD

引用次数: 2

Debate - Replacement of the Mitral Valve Under One Year of Age: Mechanical Valves Should Be Used 争论-一岁以下的二尖瓣更换:应该使用机械瓣膜

Pediatric Cardiac Surgery Annual Pub Date : 2021-01-01 DOI: 10.1053/j.pcsu.2021.03.005

David G. Lehenbauer MD, James S. Tweddell MD, David S. Winlaw MBBS, MD, FRACS

引用次数: 0

Stem Cell Therapy in Single-Ventricle Physiology: Recent Progress and Future Directions 干细胞治疗在单心室生理学:最新进展和未来方向

Pediatric Cardiac Surgery Annual Pub Date : 2021-01-01 DOI: 10.1053/j.pcsu.2021.03.003

Mohamed Abdullah MD, PhD , Samantha Kegel BS , Muthukumar Gunasekaran PhD , Progyaparamita Saha PhD , Xuebin Fu PhD , Rachana Mishra PhD , Sudhish Sharma PhD , Sunjay Kaushal MD, PhD

{"title":"Stem Cell Therapy in Single-Ventricle Physiology: Recent Progress and Future Directions","authors":"Mohamed Abdullah MD, PhD , Samantha Kegel BS , Muthukumar Gunasekaran PhD , Progyaparamita Saha PhD , Xuebin Fu PhD , Rachana Mishra PhD , Sudhish Sharma PhD , Sunjay Kaushal MD, PhD","doi":"10.1053/j.pcsu.2021.03.003","DOIUrl":"10.1053/j.pcsu.2021.03.003","url":null,"abstract":"<div>Current surgical and medical treatment options for single ventricle physiology conditions remain palliative. On the long term, despite treatment, the systemic ventricle has a significant risk of developing failure. There are unmet needs to develop novel treatment modalities to help ameliorate the ventricular dysfunction. Advances in the field of stem cell therapy have been promising for the treatment of heart failure. Numerous stem cell populations have been identified. Preclinical studies in small and large animal models provide evidence for effectiveness of this treatment modality and reveal several mechanisms of action by which stem cells exert their effect. Many clinical trials have been designed to further investigate the therapeutic potential that stem cell therapy may hold for pediatric populations with single ventricle physiology. In this review, we discuss the stem cell types used in these populations, some preclinical studies, and the clinical trials of stem cell therapy in single ventricle patients.</div>","PeriodicalId":38774,"journal":{"name":"Pediatric Cardiac Surgery Annual","volume":"24 ","pages":"Pages 67-76"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39017498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Is There Any Clinical Utility to Genetic Testing for Patients With Congenital Heart Disease? 基因检测对先天性心脏病患者有临床意义吗?

Pediatric Cardiac Surgery Annual Pub Date : 2021-01-01 DOI: 10.1053/j.pcsu.2021.04.002

Richard W. Kim MD

引用次数: 0

Ventricular Assist Device Therapy in the Fontan Circulation 心室辅助装置在方坦循环中的应用

Pediatric Cardiac Surgery Annual Pub Date : 2021-01-01 DOI: 10.1053/j.pcsu.2021.01.001

Chet R. Villa MD, Angela Lorts MD, MBA, David L.S. Morales MD

引用次数: 3

How and When Should Tetralogy of Fallot be Palliated Prior to Complete Repair? 法洛四联症在完全修复前应如何及何时进行缓和?

Pediatric Cardiac Surgery Annual Pub Date : 2021-01-01 DOI: 10.1053/j.pcsu.2021.02.002

David J. Barron FRCS(CT), Anusha Jegatheeswaran MD, PhD

{"title":"How and When Should Tetralogy of Fallot be Palliated Prior to Complete Repair?","authors":"David J. Barron FRCS(CT), Anusha Jegatheeswaran MD, PhD","doi":"10.1053/j.pcsu.2021.02.002","DOIUrl":"10.1053/j.pcsu.2021.02.002","url":null,"abstract":"<div>The controversy regarding the best or ideal surgical management of Tetralogy of Fallot (ToF) stems from the recognition of there being a spectrum of morphology and associated lesions, each of which require a different approach to achieve the three goals of minimizing mortality preserving right ventricular function long-term and minimizing reinterventions. A one-size-fits-all approach to ToF needs to be replaced by a considered and personalized approach in order to yield the best outcomes possible for individual patients. The great majority of patients with ToF undergo primary complete repair between age 3–9 months with excellent outcomes. However, the greatest challenge is the severely cyanotic neonates where primary repair is still associated with high mortality and reintervention rates. Risk factors are low weight and small/poorly developed pulmonary vasculature. High-risk neonates have better outcomes with palliation—but mortality is still high. Palliative interventions in the catherization lab are showing better outcomes than traditional BT shunt and the RVOT stent is emerging as potential game-changer. Primary neonatal repair is still recommended if weight >3 kg and Nakata >100 mm2/m2. However, neonates with low weight, small pulmonary arteries or multiple comorbidities (including ToF/AVSD and anomalous LAD) may do better with a staged approach, There is good argument for RVOT stenting as a bridge to complete repair due to its stable circulation without diastolic run off and volume loading of the circulation, and its potential to allow branch PA growth.</div>","PeriodicalId":38774,"journal":{"name":"Pediatric Cardiac Surgery Annual","volume":"24 ","pages":"Pages 77-84"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39017499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Anomalous Aortic Origin of the Coronary Arteries – State of the Art Management and Surgical Techniques 冠状动脉异常的主动脉起源-最新的治疗和手术技术

Pediatric Cardiac Surgery Annual Pub Date : 2021-01-01 DOI: 10.1053/j.pcsu.2021.03.004

Carlos Bonilla-Ramirez MD , Silvana Molossi MD, PhD , Christopher A. Caldarone MD , Ziyad M. Binsalamah MD, FRCSC

{"title":"Anomalous Aortic Origin of the Coronary Arteries – State of the Art Management and Surgical Techniques","authors":"Carlos Bonilla-Ramirez MD , Silvana Molossi MD, PhD , Christopher A. Caldarone MD , Ziyad M. Binsalamah MD, FRCSC","doi":"10.1053/j.pcsu.2021.03.004","DOIUrl":"10.1053/j.pcsu.2021.03.004","url":null,"abstract":"<div>Anomalous aortic origin of a coronary artery (AAOCA) can be associated with myocardial ischemia and sudden cardiac arrest. We describe and compare the management and surgical techniques for patients with AAOCA. Patients presenting to the Coronary Artery Anomalies Program are evaluated and managed following a standardized approach. Our approach and data were compared to other single-center and multi-institutional data and results. Patients with AAOCA present as an incidental finding approximately 50% of the time. Advanced axial imaging is essential to define the anatomic characteristics of this lesion. Preoperative and postoperative assessment of myocardial perfusion with provocative testing is feasible and contributes to risk stratification. The surgical techniques for AAOCA repair include coronary unroofing, transection and reimplantation, and neo-ostium creation, among others. In general, surgical repair of AAOCA can mitigate the risk of ischemia with low mortality. The specific morbidities and complications of each different technique should be considered during the surgical planning. Surgical repair of AAOCA can mitigate the risk of ischemia with a low associated mortality but with clinically relevant morbidities. Long-term follow-up is necessary to accurately balance the risks of repaired and unrepaired AAOCA.</div>","PeriodicalId":38774,"journal":{"name":"Pediatric Cardiac Surgery Annual","volume":"24 ","pages":"Pages 85-94"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39017500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Cardiac Surgery: A Complete Guide 心脏外科:完整指南

Pediatric Cardiac Surgery Annual Pub Date : 2020-12-01 DOI: 10.1007/978-3-030-24174-2

引用次数: 4

Cardiac Resynchronization Therapy for Heart Failure 心脏再同步化治疗心力衰竭

Pediatric Cardiac Surgery Annual Pub Date : 2020-02-12 DOI: 10.1007/978-3-030-24174-2_66

Mumin R. Noor, Rebecca E. Lane, Owais Dar

引用次数: 0