Pharma-KritikPub Date : 2021-09-30DOI: 10.37667/pk.2021.1170
E. Gysling
{"title":"Antibiotika bei Kindern nur zurückhaltend verschreiben!","authors":"E. Gysling","doi":"10.37667/pk.2021.1170","DOIUrl":"https://doi.org/10.37667/pk.2021.1170","url":null,"abstract":"\u0000In einer Doppelblindstudie erhielten Kinder bei Atemwegs-infekten Amoxicillin oder Placebo. Es ergab sich kein relevanter Vorteil der Antibiotika-Therapie. \u0000\u0000","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44266815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-09-30DOI: 10.37667/pk.2021.1169
E. Gysling
{"title":"Mehr Kolonkarzinome nach häufiger Antibiotika-Therapie","authors":"E. Gysling","doi":"10.37667/pk.2021.1169","DOIUrl":"https://doi.org/10.37667/pk.2021.1169","url":null,"abstract":"\u0000 \u0000In einer schwedischen Fall-Kontrollstudie wurden 40'545 Personen erfasst, die an einem kolorektalen Karzinom erkrankt waren. Gemäss einer Analyse verschiedener Daten-banken hatten diejenigen Patientinnen und Patienten, die häufig Antibiotika erhalten hatten, ein höheres Risiko für ein proximales Kolonkarzinom (nicht aber für ein Rektumkarzinom). \u0000\u0000","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43014523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-08-30DOI: 10.37667/pk.2021.1164
E. Gysling
{"title":"Wieviele Nebenwirkungen verursachen die Biologika?","authors":"E. Gysling","doi":"10.37667/pk.2021.1164","DOIUrl":"https://doi.org/10.37667/pk.2021.1164","url":null,"abstract":"Biologika, die bei entzündlichen Darmkrankheiten eingesetzt werden, sind gemäss einer Untersuchung, bei der die Behandelten regelmässig befragt wurden, häufiger als vermutet. ","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47788884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-08-30DOI: 10.1007/bf03231091
S. Weiler
{"title":"Mit weniger mehr erreichen","authors":"S. Weiler","doi":"10.1007/bf03231091","DOIUrl":"https://doi.org/10.1007/bf03231091","url":null,"abstract":"","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52171677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-08-30DOI: 10.37667/pk.2021.1163
E. Gysling
{"title":"Nicht-steroidale Entzündungshemmer bei COVID-19 unproblematisch","authors":"E. Gysling","doi":"10.37667/pk.2021.1163","DOIUrl":"https://doi.org/10.37667/pk.2021.1163","url":null,"abstract":"Entgegen den im Frühjahr 2020 geäusserten Vermutungen beeinflussen nicht-steroidale Entzündungshemmer (z.B. Ibuprofen) das Auftreten und den Verlauf einer COVID-19-Erkrankung nicht ungünstig. ","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49289695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-08-30DOI: 10.37667/pk.2021.1162
E. Gysling
{"title":"Verlängertes QTc-Intervall wird zu wenig beachtet","authors":"E. Gysling","doi":"10.37667/pk.2021.1162","DOIUrl":"https://doi.org/10.37667/pk.2021.1162","url":null,"abstract":"Sehr viele Medikamente können zu einer Verlängerung des QTc-Intervalls und damit eventuell zu gefährlichen Arrhythmien führen. Die entsprechende Information findet sich nicht immer in der offiziellen Dokumentation. ","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43744155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-08-03DOI: 10.37667/pk.2021.1157
N. Marty
{"title":"Capsaicin: Hypersensitivität bei wiederholtem Kontakt","authors":"N. Marty","doi":"10.37667/pk.2021.1157","DOIUrl":"https://doi.org/10.37667/pk.2021.1157","url":null,"abstract":"\u0000Capsaicin, das in niedriger Konzentration lokal gegen Schmerzen eingesetzt wird, kann zu Überempfindlichkeitsreaktionen führen. Diese treten besonders nach wiederholter Anwendung auf und sind vereinzelt recht heftig. Auch Angehörige der Gesundheitsberufe, die solche Präparate applizieren, sind gefährdet, selbst wenn sie entsprechende Vorsichtsmassnahmen treffen. \u0000\u0000","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47752572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-08-03DOI: 10.37667/pk.2021.1156
E. Gysling
{"title":"Methotrexat stört COVID-19-Impfwirkung","authors":"E. Gysling","doi":"10.37667/pk.2021.1156","DOIUrl":"https://doi.org/10.37667/pk.2021.1156","url":null,"abstract":"\u0000 Bei Personen, die zweimal mit dem mRNA-Impfstoff von Pfizer-BioNTech (BNT162b2) geimpft worden waren, wurde die humorale Immunantwort (IgG-Antikörper) bestimmt. Diejenigen, die wegen einer immunvermittelten Krankheit mit Methotrexat behandelt wurden, hatten nur in 62% eine als adäquat beurteilte Immunantwort. \u0000\u0000","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43497561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-08-03DOI: 10.37667/pk.2021.1158
E. Gysling
{"title":"Gefährliche Antikoagulantienblutungen","authors":"E. Gysling","doi":"10.37667/pk.2021.1158","DOIUrl":"https://doi.org/10.37667/pk.2021.1158","url":null,"abstract":"\u0000Obwohl verschiedene Antidote verfügbar sind, führen auch die neuen direkten oralen Antikoagulantien (DOACs) zu gefährlichen Blutungen, die gemäss einer Meta-Analyse in fast 18% zum Tode führen. Die Wiederaufnahme der Antikoagulation kann erneute Blutungen verursachen! \u0000\u0000","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44269553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pharma-KritikPub Date : 2021-04-03DOI: 10.37667/pk.2020.1137
E. Gysling
{"title":"Ciprofloxacin verstärkt Tizanidinwirkung","authors":"E. Gysling","doi":"10.37667/pk.2020.1137","DOIUrl":"https://doi.org/10.37667/pk.2020.1137","url":null,"abstract":"\u0000 Für den Metabolismus von Tizanidin (Sirdalud®) spielt das Zytochrom CYP1A2 eine wichtige Rolle. CYP1A2-Hemmer wie Ciprofloxacin (Ciproxin® u.a.) können des-halb zu verstärkten Nebenwirkungen von Tizanidin führen, was mit einer Analyse der Nebenwirkungs-Datenbank der WHO bestätigt werden konnte. \u0000\u0000","PeriodicalId":38760,"journal":{"name":"Pharma-Kritik","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49195938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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