K. Disha, S. Schulz, M. Breuer, T. Owais, E. Girdauskas, T. Kuntze
{"title":"Novel Association of a Familial TGFBR1 Mutation in Loeys-Dietz Syndrome with Concomitant Hematologic Malignancy","authors":"K. Disha, S. Schulz, M. Breuer, T. Owais, E. Girdauskas, T. Kuntze","doi":"10.5090/kjtcs.2019.52.5.376","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.5.376","url":null,"abstract":"Concomitant Loeys-Dietz syndrome (LDS) and hematologic malignancies are exceptionally rare. This is the first report of a patient operated on for aortic root dilation who had been previously diagnosed with LDS and B-cell-lymphoma. After completion of chemotherapy and complete remission, an elective valve-sparing aortic root replacement (using the David-V method) was performed. Due to the positive family history, pre-operative genetic counseling was conducted, and revealed LDS with a TGFBR1 (transforming growth factor beta receptor type I) mutation in 6 probands of the family, albeit in 1 of them posthumously. This missense mutation has been previously described in relation to aortic dissection, but a causative relationship to malignancy has so far neither been proposed nor proven.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"376 - 379"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48747313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ilkun Park, Sumin Shin, H. Kim, Y. Choi, Jhingook Kim, J. Zo, Y. Shim, J. Cho
{"title":"Primary Chest Wall Sarcoma: Surgical Outcomes and Prognostic Factors","authors":"Ilkun Park, Sumin Shin, H. Kim, Y. Choi, Jhingook Kim, J. Zo, Y. Shim, J. Cho","doi":"10.5090/kjtcs.2019.52.5.360","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.5.360","url":null,"abstract":"Background Primary chest wall sarcoma is a rare disease with limited reports of surgical resection. Methods This retrospective review included 41 patients with primary chest wall sarcoma who underwent chest wall resection and reconstruction from 2001 to 2015. The clinical, histologic, and surgical variables were collected and analyzed by univariate and multivariate Cox regression analyses for overall survival (OS) and recurrence-free survival (RFS). Results The OS rates at 5 and 10 years were 73% and 61%, respectively. The RFS rate at 10 years was 57.1%. Multivariate Cox regression analysis revealed old age (hazard ratio [HR], 5.16; 95% confidence interval [CI], 1.71–15.48) as a significant risk factor for death. A surgical resection margin distance of less than 1.5 cm (HR, 15.759; 95% CI, 1.78–139.46) and histologic grade III (HR, 28.36; 95% CI, 2.76–290.87) were independent risk factors for recurrence. Conclusion Long-term OS and RFS after the surgical resection of primary chest wall sarcoma were clinically acceptable.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"360 - 367"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41761502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shin-ah Son, Chae-Min Bae, Tak-Hyuk Oh, Y. Do, Y. Seok, J. Cho
{"title":"Traumatic Right Pulmonary Artery Rupture after Accidentally Being Stepped on the Chest","authors":"Shin-ah Son, Chae-Min Bae, Tak-Hyuk Oh, Y. Do, Y. Seok, J. Cho","doi":"10.5090/kjtcs.2019.52.5.380","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.5.380","url":null,"abstract":"Traumatic pulmonary artery rupture is a rare, life-threatening injury. Currently, no strict guidelines for its management exist. Herein, we report a successful surgical repair of a right pulmonary artery rupture caused by being stepped on.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"380 - 383"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42565316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Yi, P. Choi, S. Jeong, J. Bang, Jae Hwa Jeong, JooHyun Cho
{"title":"Prognostic Significance of Cigarette Smoking in Association with Histologic Subtypes of Resected Lung Adenocarcinoma","authors":"J. Yi, P. Choi, S. Jeong, J. Bang, Jae Hwa Jeong, JooHyun Cho","doi":"10.5090/kjtcs.2019.52.5.342","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.5.342","url":null,"abstract":"Background Smokers with lung adenocarcinoma have a worse prognosis than those who have never smoked; the reasons for this are unclear. We aimed to elucidate the impact of smoking on patients’ prognosis and the association between smoking and clinicopathologic factors, particularly histologic subtypes. Methods We reviewed the records of 233 patients with pathologic stage T1-4N0-2M0 lung adenocarcinomas who underwent surgery between January 2004 and July 2015. The histologic subtypes of tumors were reassessed according to the 2015 World Health Organization classification. Results In total, 114 patients had a history of smoking. The overall survival probabilities differed between never-smokers and ever-smokers (80.8% and 65.1%, respectively; p=0.003). In multivariate analyses, the predominant histologic subtype was an independent poor prognostic factor. Smoking history and tumor size >3 cm were independent predictors of solid or micropapillary (SOL/MIP)-predominance in the logistic regression analysis. Smoking quantity (pack-years) in patients with SOL/MIP-predominant tumors was greater than in those with lepidic-predominant tumors (p=0.000). However, there was no significant difference in smoking quantity between patients with SOL/MIP-predominant tumors and those whose tumors had non-predominant SOL/MIP components (p=0.150). Conclusion Smoking was found to be closely associated with SOL/MIP-predominance in lung adenocarcinoma. Greater smoking quantity was related to the presence of a SOL/MIP component.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"342 - 352"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47094087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mid-Term Results of Using the Seal Thoracic Stent Graft in Cases of Aortopathy: A Single-Institution Experience","authors":"J. Cho, J. Jang, C. Lee, Sun Hyun Hwang","doi":"10.5090/kjtcs.2019.52.5.335","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.5.335","url":null,"abstract":"Background The endovascular approach to aortic disease treatment has been increasingly utilized in the past 2 decades. This study aimed to determine the long-term results of using the Seal thoracic stent graft. Methods We retrospectively reviewed the outcomes of patients who underwent thoracic endovascular aortic repair or a hybrid procedure using the Seal thoracic stent graft (S&G Biotech, Seongnam, Korea) from January 2008 to July 2018 at a single institution. We investigated in-hospital mortality and the incidence of postoperative complications. We also investigated the mid-term survival rate and incidence of aorta-related complications. Results Among 72 patients with stent grafts, 15 patients underwent the hybrid procedure and 21 underwent emergency surgery. The mean follow-up period was 37.86±30.73 months (range, 0–124 months). Five patients (6.9%) died within 30 days. Two patients developed cerebrovascular accidents. Spinal cord injury occurred in 2 patients. Postoperative renal failure, postoperative extracorporeal membrane oxygenation support, and pneumonia were reported in 3, 1, and 6 patients, respectively. Stent-related aortic complications were observed in 5 patients (6.8%). The 1- and 5-year survival and freedom from stent-induced aortic event rates were 81.5% and 58.7%, and 97.0% and 89.1%, respectively. Conclusion The use of the Seal thoracic stent graft yielded good mid-term results. Further studies are needed to examine the long-term outcomes of this device.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"335 - 341"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43824671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hybrid Approach for Treatment of Multiple Traumatic Injuries of the Heart, Aorta, and Abdominal Organs","authors":"Seon Hee Kim, Seunghwan Song, H. Cho, C. Park","doi":"10.5090/kjtcs.2019.52.5.372","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.5.372","url":null,"abstract":"A 55-year-old man was admitted to the trauma center after a car accident. Cardiac tamponade, traumatic aortic injury, and hemoperitoneum were diagnosed by ultrasonography. The trauma surgeon, cardiac surgeon, and interventional radiologist discussed the prioritization of interventions. Multi-detector computed tomography was carried out first to determine the severity and extent of the injuries, followed by exploratory sternotomy to repair a left auricle rupture. A damage control laparotomy was then performed to control mesenteric bleeding. Lastly, a descending thoracic aorta injury was treated by endovascular stenting. These procedures were performed in the hybrid-angio room. The patient was discharged on postoperative day 135, without complications.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"372 - 375"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49100043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bentall Operation in a Patient with a Unicommissural Unicuspid Aortic Valve","authors":"Sung Joon Park, Jae Hoon Lee, E. Chung","doi":"10.5090/kjtcs.2019.52.5.368","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.5.368","url":null,"abstract":"A unicuspid aortic valve is a rare congenital malformation that frequently presents with valvular dysfunction and dilatation or aortic aneurysm, requiring combined aortic valve surgery and aortic repair. Some patients show severe valve calcification extending into the interventricular septum, possibly resulting in damage to the conduction system during debridement for valve replacement. We present a rare case of severe aortic stenosis with a unicommissural unicuspid aortic valve diagnosed by preoperative transesophageal echocardiography in a 36-year-old man. After composite graft replacement of the aortic valve, aortic root, and ascending aorta, a permanent pacemaker was placed because of postoperative complete heart block.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"368 - 371"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48527002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanna Jung, Sungsoo Lee, Kook-Yang Park, Tae Yun Oh
{"title":"Historical Perspectives of The Korean Society for Thoracic and Cardiovascular Surgery: The Pioneer of General Thoracic Surgery in Korea: Pyung-Kan Koh 고병간 (1899-1966).","authors":"Hanna Jung, Sungsoo Lee, Kook-Yang Park, Tae Yun Oh","doi":"10.5090/kjtcs.2019.52.5.331","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.5.331","url":null,"abstract":"","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 5","pages":"331-334"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/cf/kjtcvs-52-331.PMC6785164.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41215253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jae Won Choi, J. Choi, Kyung Hyuk Go, Y. Cheon, J. W. Kim, C. Lee, H. Park
{"title":"Immunoglobulin G4-Related Aortitis of the Abdominal Aorta","authors":"Jae Won Choi, J. Choi, Kyung Hyuk Go, Y. Cheon, J. W. Kim, C. Lee, H. Park","doi":"10.5090/kjtcs.2019.52.4.239","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.4.239","url":null,"abstract":"Noninfectious aortitis, inflammatory abdominal periaortitis, and idiopathic retroperitoneal fibrosis are chronic inflammatory diseases with unclear causes. Recent studies have shown that some cases of aortitis are associated with immunoglobulin G4 (IgG4)-related systemic disease. Herein, we report a case of IgG4-related aortitis (IgG4-RA) that was diagnosed after surgery. Our patient was a 46-year-old man who had experienced abdominal pain for several weeks. Preoperative evaluations revealed an area of aortitis on the infrarenal aorta. He underwent surgery, and histological examination resulted in a diagnosis of IgG4-RA.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"239 - 242"},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43602383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Historical Perspectives of Korean Society for Thoracic and Cardiovascular Surgery: Inauguration and Activities of the Historical Records Preservation Committee","authors":"K. Park, Sungsoo Lee, B. Chang, Tae Yun Oh","doi":"10.5090/kjtcs.2019.52.4.191","DOIUrl":"https://doi.org/10.5090/kjtcs.2019.52.4.191","url":null,"abstract":"The Korean Society for Thoracic and Cardiovascular Surgery (KTCVS) was founded in 1968 and celebrated the 50th anniversary of its founding in 2018. The launch of the KTCVS may seem somewhat recent, given that the American Association for Thoracic Surgery was founded in 1917. However, considering the circumstances of the Korean medical community after the Japanese occupation (1910–1945), World War II (1940–1945), and the Korean War (1950–1953), this apparent delay is understandable. Even before the foundation of the KTCVS, the early pioneers of thoracic and cardiovascular surgery promptly adopted medical technologies from more advanced countries such as the United States, and contributed significantly to both cardiac and thoracic surgery despite difficult circumstances. In 2012, before the 50th anniversary of the founding of the KTCVS, members shared the opinion that objective records of the activities of the early pioneers should be identified and preserved, and reacted positively towards the necessity for historians who would preserve such records. With this background, the Historical Records Preservation Committee of the KTCVS (hereinafter, referred to as ‘the Committee’) was launched. The Committee published a white paper on the history of thoracic and cardiovascular surgery in 2015 and held an exhibition of the achievements of the pioneers at the 50th anniversary of the founding of the KTCVS. The Committee also published a book entitled “The history of Korean thoracic surgery with photographs: celebrating the 50th anniversary of the society.” The Committee will keep making efforts to find and preserve materials related to activities during the early development of thoracic and cardiovascular surgery in Korea.","PeriodicalId":38678,"journal":{"name":"Korean Journal of Thoracic and Cardiovascular Surgery","volume":"52 1","pages":"191 - 194"},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41468420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}