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Pakistan Journal of Life and Social Sciences (PJLSS)最新文献

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Social Activism as a Factor of Information Security (Theoretical and Methodological Aspect) 社会活动是信息安全的一个因素（理论与方法论方面）
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2024-07-26 DOI: 10.57239/pjlss-2024-22.1.00248
Nurzhanova Sharipa Syzdykovna, Kondratskaya Victoria Leonidovna
{"title":"Social Activism as a Factor of Information Security (Theoretical and Methodological Aspect)","authors":"Nurzhanova Sharipa Syzdykovna, Kondratskaya Victoria Leonidovna","doi":"10.57239/pjlss-2024-22.1.00248","DOIUrl":"https://doi.org/10.57239/pjlss-2024-22.1.00248","url":null,"abstract":"The article presents the connection of Internet activism and social activity with the information security of the state. The main views on social activity are described and methodological approaches to the study of social activism are set out. Online-activism is presented as one of the factors of state information security. ","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"14 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141801552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-silico Molecular Docking ADME Study and Synthesis of Eugenol Derivatives as Antiproliferative 丁香酚抗增殖衍生物的硅对接ADME研究及合成
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2024-01-01 DOI: 10.57239/pjlss-2024-22.1.00338
Farah Haidar Abdulredha
{"title":"In-silico Molecular Docking ADME Study and Synthesis of Eugenol Derivatives as Antiproliferative","authors":"Farah Haidar Abdulredha","doi":"10.57239/pjlss-2024-22.1.00338","DOIUrl":"https://doi.org/10.57239/pjlss-2024-22.1.00338","url":null,"abstract":"The use of semisynthetic alterations to natural materials has provided us with several anticancer medications.The current study involves the synthetic modification of eugenol, a natural substance, to create novel anticancer drugs.The ultimate compounds were verified for their structure using NMR, IR, and mass methods.Based on the cytotoxicity data, compound 17 containing morpholine was identified as the most potent cytotoxic agent, exhibiting IC50 values of 1.71 M (MCF-7), 1.84 M (SKOV3), and 1.1 M (PC-3).Additionally, it demonstrated inhibitory activity against thymidylate synthase (TS) with an IC50 value of 0.81 M.Subsequent cellular investigations demonstrated that compound 17 has the ability to trigger apoptosis and halt the cell cycle specifically during the S phase in PC-3 cancer.Based on the docking investigation, compound 17 is very likely to be a transition state inhibitor, as it exhibited a comparable interaction to 5-fluorouracil.The results obtained from docking and biological assessment are supported by in silico pharmacokinetics and DFT computational investigations, which indicate a favorable pharmacokinetic profile for the medicine to be administered orally.Compound 17 shown potential as a promising inhibitor of thymidylate synthase (TS), effectively inhibiting DNA synthesis and thus reducing DNA damage in prostate cancer cells.","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"http://dx.doi.org/10.57239/pjlss-2024-22.1.00338","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147907894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of foliar spray with silicon, boron, and gibberellic acid on the Characteristics of vegetative and root growth of Strawberry plants (Fragaria x ananassa Duch.) cv. Albion 叶面喷施硅、硼和赤霉素酸对草莓营养和根系生长特性的影响阿尔比恩
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2024-01-01 DOI: 10.57239/pjlss-2024-22.1.00272
Mohaned A. Al-Sarraf, Prof. Dr. Jassim MA Al-A Areji
{"title":"Effect of foliar spray with silicon, boron, and gibberellic acid on the Characteristics of vegetative and root growth of Strawberry plants (Fragaria x ananassa Duch.) cv. Albion","authors":"Mohaned A. Al-Sarraf, Prof. Dr. Jassim MA Al-A Areji","doi":"10.57239/pjlss-2024-22.1.00272","DOIUrl":"https://doi.org/10.57239/pjlss-2024-22.1.00272","url":null,"abstract":"of Mosul to find out the effects of foliar spray by using three concentrations of silicon (0 and 2 and 3 mmol Si L-1) using potassium silicate (18%) Si) and boron in three concentrations also (0, 25 and 50 mg B L-1) by using boric acid (17% B) and two concentrations of gibberellic acid in two concentrations.They 0 and 75 mg GA3 L-1 in some characteristics of vegetative growth of plants Strawberry (strawberry) (Fragaria x ananassa Duch.) cv.Albion For the period from 12/1/2022 until 6/1/2023 Except the description of the number of runners, which was taken on 9/15/2023 , the plants were sprayed three times with each of silicon and boron and once with gibberellic acid during the study period.The study was applied using a design RCBD.Three and nine replicate plants for each experimental unit.The results showed foliar spraying with silicon, boron, and gibberellic acid separately, as well as all interactions between them.Especially at concentrations of 3 mmol Si L-1 and 50 mg B L-1 with 75 mg GA3 L-1, it led to a significant increase in the following characteristics: total chlorophyll in leaves, plant leaves area, crown diameter, dry weight of the shoot and root system of the plants, and the number of runners for each plant.Compared to the control treatment.","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"http://dx.doi.org/10.57239/pjlss-2024-22.1.00272","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147894656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Prisons in the History of Islamic State 伊斯兰国历史上的监狱
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2024-01-01 DOI: 10.57239/pjlss-2024-22.2.00725
Khaled Hasan AI-Jabali
{"title":"The Prisons in the History of Islamic State","authors":"Khaled Hasan AI-Jabali","doi":"10.57239/pjlss-2024-22.2.00725","DOIUrl":"https://doi.org/10.57239/pjlss-2024-22.2.00725","url":null,"abstract":"After an intensive investigation of the heritage books, it has become clear through historical texts that prisons are necessary to prevent harm to people and preserve rights and property.It turns out that imprisonment was known and practiced in the early days of Islam, and clear evidence of this has come from the succession of periods throughout history regarding the use of this punitive method.Evidence for this is what we monitored of names that were famous and distributed in the various regions of the Arab Islamic state, and we also knew many types of prisons, some of which were found to be specialized in imprisoning the prisoner according to the crime he committed.Despite this, although I was able to monitor the largest possible number of narrations, I do not claim that I have come across all of them, because perfection belongs to God alone.","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"22 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://doi.org/10.57239/pjlss-2024-22.2.00725","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Language Gambit: Code-Switching, English Competence, and the Jordanian University Bragging Social Network 语言策略：语码转换、英语能力和约旦大学吹牛社交网络
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2024-01-01 DOI: 10.57239/pjlss-2024-22.2.0088
Ma'an Al Ma'aytah, Ahmed Alamro, Mahmoud Alghizzawi, Jassim Ahmad Al-Gasawneh, Orouba Al Muhaisen
{"title":"Language Gambit: Code-Switching, English Competence, and the Jordanian University Bragging Social Network","authors":"Ma'an Al Ma'aytah, Ahmed Alamro, Mahmoud Alghizzawi, Jassim Ahmad Al-Gasawneh, Orouba Al Muhaisen","doi":"10.57239/pjlss-2024-22.2.0088","DOIUrl":"https://doi.org/10.57239/pjlss-2024-22.2.0088","url":null,"abstract":"The aim of this research is to establish the relations between codeswitching, English performance, social capital, and social class among Jordanian college learners.The study uses a selfadministrated questionnaire, interviews, and social network analysis to achieve its objective.The results also align with the null hypothesis concerning English language usage and code-switching at varying levels of social capital, as well as perceived social and economic reward, power, and status.It also includes an analysis of how students develop a tendency to over emphasize their fluency in English, as well as the moderation effect of the exercise of English on the relation between code-switching and status.In the case of the qualitative data, we use structural equation modelling (SEM), descriptive and inferential statistics, and theme analysis to analyze the retrieved data.The findings will thus describe the overall language use, interpersonal processes, and perceived opportunities in the context of the Jordanian university scene.As a result, by bringing up the previously ignored topic of boasting in English and presenting a more nuanced view of code-switching as a social strategy tool, the study attempts to offer new angles.The article focuses on the possible implications of language policies and practices intended for language diversity and students' assimilation.Thus, adopting a stringent multi-method approach specific to the Jordanian context, this work maps language use, social capital, and social status, contributing to the existing literature's deficit.","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"22 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"http://dx.doi.org/10.57239/pjlss-2024-22.2.0088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147900102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the Impact of Sand Mining on Land Change and Water Quality in the River Bila, South Sulawesi, Indonesia 印度尼西亚南苏拉威西比拉河采砂对土地变化和水质影响的评价
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2024-01-01 DOI: 10.57239/pjlss-2024-22.2.000201
Muh Assabul Kahfi Selman
{"title":"Assessment of the Impact of Sand Mining on Land Change and Water Quality in the River Bila, South Sulawesi, Indonesia","authors":"Muh Assabul Kahfi Selman","doi":"10.57239/pjlss-2024-22.2.000201","DOIUrl":"https://doi.org/10.57239/pjlss-2024-22.2.000201","url":null,"abstract":"","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"22 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://doi.org/10.57239/pjlss-2024-22.2.000201","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147922031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing Project-based Learning (PBL) in Cloud Education Models for Word Software Courses 在Word软件课程的云教学模式中加强基于项目的学习(PBL
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2023-01-01 DOI: 10.57239/pjlss-2023-21.1.0024
Shi Tang, Sirirat Petsangsri, Thanin Ratana-Olarn
{"title":"Enhancing Project-based Learning (PBL) in Cloud Education Models for Word Software Courses","authors":"Shi Tang, Sirirat Petsangsri, Thanin Ratana-Olarn","doi":"10.57239/pjlss-2023-21.1.0024","DOIUrl":"https://doi.org/10.57239/pjlss-2023-21.1.0024","url":null,"abstract":"","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135401630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing Project-Based Blended Learning (PJBBL) Model in Algorithm Design: A Comprehensive Needs Analysis 基于项目的混合学习(PJBBL)模型在算法设计中的改进:一个全面的需求分析
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2023-01-01 DOI: 10.57239/pjlss-2023-21.1.0026
Tao Lu, John Morris, Thanin Ratana-Olarn
{"title":"Enhancing Project-Based Blended Learning (PJBBL) Model in Algorithm Design: A Comprehensive Needs Analysis","authors":"Tao Lu, John Morris, Thanin Ratana-Olarn","doi":"10.57239/pjlss-2023-21.1.0026","DOIUrl":"https://doi.org/10.57239/pjlss-2023-21.1.0026","url":null,"abstract":"","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135401612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rank-and-File Employees’ Work Attitude, Motivation and Performance in an Academe 某研究院普通员工的工作态度、工作动机与工作绩效
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2023-01-01 DOI: 10.57239/pjlss-2023-21.1.0019
Renecynth B. Jaurigue, Noemi G. Laspinas, Hyacin S. Inojales, Reygei B. Hermano
{"title":"Rank-and-File Employees’ Work Attitude, Motivation and Performance in an Academe","authors":"Renecynth B. Jaurigue, Noemi G. Laspinas, Hyacin S. Inojales, Reygei B. Hermano","doi":"10.57239/pjlss-2023-21.1.0019","DOIUrl":"https://doi.org/10.57239/pjlss-2023-21.1.0019","url":null,"abstract":"","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135401643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustainable Tourism Management in Post Pandemic: LessonLearned from Ponggok Village Tourism Community Governance 大流行后的可持续旅游管理:从峰谷村旅游社区治理中吸取的教训
Pakistan Journal of Life and Social Sciences (PJLSS) Pub Date : 2023-01-01 DOI: 10.57239/pjlss-2023-21.1.0028
Fatmawati Fahmi Al Fikri, Rino Ardhian Nugroho, Sudarmo .
{"title":"Sustainable Tourism Management in Post Pandemic: LessonLearned from Ponggok Village Tourism Community Governance","authors":"Fatmawati Fahmi Al Fikri, Rino Ardhian Nugroho, Sudarmo .","doi":"10.57239/pjlss-2023-21.1.0028","DOIUrl":"https://doi.org/10.57239/pjlss-2023-21.1.0028","url":null,"abstract":"","PeriodicalId":384043,"journal":{"name":"Pakistan Journal of Life and Social Sciences (PJLSS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135400719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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