Dentistry: Advanced Research最新文献

{"title":"Cost and Time Differences Between Three Types of Restorations for Primary Teeth: Amalgam, Composite and Glass-ionomer Cement","authors":"H. Phan, J. Powers, F. García-Godoy, Timothy Brown, L. Pinzon","doi":"10.21203/rs.3.rs-75537/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-75537/v1","url":null,"abstract":"\u0000 Background: Early Childhood Caries is the most prevalent chronic disease among children in the United States. Three common approaches for treatment of dental caries in general population include: amalgam, composite, and glass ionomer. The purpose of this study was to measure the treatment cost differences for amalgam, composite, and atraumatic restorative treatment (ART) restorations of primary teeth and evaluate possible factors that could influence the cost of treatment. Methods: This cross-sectional study randomly selected data of 120 restorations from a clinical observational study of the restoration of primary teeth in children aged 5 – 10 years old. The 120 selected restorations in primary teeth, half with two surfaces and half with three surfaces, were performed by two operators at the Asian Health Center and Centro American Resources Center in California. Data were analyzed using multivariable linear regression. Results: Performing ART was found to take 7.8 minutes less than amalgam (p<0.01) and 19.0 minutes less than composite. ART was found to be 6.4% (p=0.01) less costly than amalgam and 62.4% (p<0.01) less costly than composite. Conclusions: ART was found to be the least costly treatment compared to amalgam and composite restoration procedures. ART also required the shortest time during the clinical procedure. Trial Registration: UCSF CHR Number: H55840-32823-02","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127306599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Blood and Saliva Contamination of the Implant-Abutment Interface on the Amount of Preload","authors":"H. Jalali, M. Moslemion, Saeid Nokar","doi":"10.29011/2574-7347.100054","DOIUrl":"https://doi.org/10.29011/2574-7347.100054","url":null,"abstract":"Effect and of the interface the Abstract Background and Objectives: Screw loosening after implant treatment is due to several factors including reduction in optimal preload. This study aimed to assess the effect of blood and saliva contamination of the implant-abutment interface on the amount of preload. Materials and Methods: In this in vitro experimental study, 18 cement-retained base metal crowns were fabricated on the same number of abutments with 45 ° angle relative to the horizontal line using the conventional casting method. The samples were randomly divided into three groups of C, B and S (n=6). The abutments with titanium screws were torques to 30 Ncm on fixtures. After five minutes, the screws were tightened again to the same torque level. After 10 minutes, maximum detorque value was measured. In group C, the abutment screws were torqued again to 30 Ncm. In groups B and S, implant-abutment interface was contaminated with blood and saliva, respectively after unscrewing and then the screws were tightened again to 30 Ncm. After cyclic loading (one million cycles), maximum detorque value was measured. Data were analyzed using one-way ANOVA. Results: A significant reduction occurred in detorque value in all three groups after cyclic loading compared to the baseline detorque value (P<0.001) but the difference among the three groups was not significant (P=0.221). Conclusion: Within the limitations of this study, the results showed that blood or saliva contamination of the implant-abutment interface had no significant effect on preload.","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130524870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Body and Bacteria","authors":"S. Kumar","doi":"10.29011/2574-7347.100053","DOIUrl":"https://doi.org/10.29011/2574-7347.100053","url":null,"abstract":"The expression of cell function is depended upon the activity of mitochondria. The key of evolution has depended upon the number and shape of mitochondria is actively working in the differentiated cell by the observation of bio-imaging method because differentiated function depends upon mitochondria job. On the processing of carcinogenesis mitochondria respiratory dysfunction has inevitably appeared. To avoid cancer suffering, it is necessary for human-being to protect mitochondrial function. Nuclear DNA was covered by double membrane, but mitochondria DNA has not covered by membrane, naked DNA. So, carcinogen, radiation, ultraviolet can easily damage mitochondria DNA 10 times more fragile than nuclear DNA. Human being has named some hundreds of bacteria, but we are letting our lives by 1000 trillion intestinal bacteria, human body has constituted from 60 trillion cells, so this population is only under 1% compared with them. Furthermore, our higher animal cell is sponsored from 1~2000 α-proteo-bacteria. This means that higher animal cell is sponsored by many of original bacteria. So, our life is the matrix among bacteria which let our higher animal cell live along. Joshua Lederberg, novel prize (science, 228, 287, 2000) 1 have proposed that host and co-existing microbiota are collective body which are complicated with many gene information. So, we should think “super-organism” and we don’t think that microbiota is bad fellow but think that the mutual relationship between host and normal flora which constitute this super-organism.","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122035349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preamble About Periodontal Disease: The Diagnose","authors":"J. Kina, Eunice Fumico Umeda Kina","doi":"10.29011/2574-7347.100052","DOIUrl":"https://doi.org/10.29011/2574-7347.100052","url":null,"abstract":"Periodontal disease one of the most common and prevalent diseases of the oral cavity has been a challenge in its etiology, diagnosis and treatment. The etiology of periodontal disease is multifactorial and it is considered that biofilm plays an essential role in its development and evolution [1]. Due periodontal disease development be dependent of the bacteria and various predisposing risk factors that are nonspecific for each individual and also in the same individual are unspecific since at a determined moment may trigger periodontal disease and at another moment may not have the same pathological capacity to trigger periodontal disease makes periodontal disease a difficult challenge to be solved [2]. Manly when the diagnose of the etiologic factors that initiate periodontal disease needs to be performed since to treat any disease is always extremely necessary to eliminate or to establish a control in all etiologic factors which are responsible for disease activity [2,3]. Then if the main factors that will be always necessary to initiate periodontal disease are bacteria is logic to establish a control in bacteria development [1]. However, establishing a control in bacteria development may be enough to control periodontal disease? This approach is always unpredictable because only bacteria are not sufficient to initiate periodontitis [1]. The predisposing risk factors always will be necessary to help bacteria developing periodontal disease [2,3]. If to treat a disease is necessary to know all etiologic factors and their inherent pathological mechanisms which may be associated with disease establishment and progression [4-6], are the methods applied up to know to establish a periodontal disease diagnostic reliable? The methods applied to diagnose periodontal disease are based in clinical and radiographic parameters which do not seem sufficient to diagnosis periodontal disease mainly its acute destructive phase always interleaved by a chronic quiescent phase. The clinical diagnosis methods are based in probing deep, probing deep bleeding, attachment levels measures, and tooth mobility. The accuracy of these clinical diagnostic methods may show falsepositive results, inducing evaluations and interpretations that may compromise the diagnosis, bringing therapeutic implications such as therapeutic planning and therapeutic follow-up. The periodontal diagnostic procedures should be useful to inform what type of periodontal disease is present, where it is located, the severity of the periodontal disease, and if it is active or inactive [5,7].","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"138 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122568028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Observation of the Effects of CAD/CAM Glass-Ceramic Onlay in the Restoration of Mandibular Second Molar","authors":"Lin Qing, X. Jing","doi":"10.29011/2574-7347.100074","DOIUrl":"https://doi.org/10.29011/2574-7347.100074","url":null,"abstract":"the Effects of Glass-Ceramic Abstract The objective of this study is to evaluate the clinical effects of the CAD/CAM glass-ceramic onlay in the restoration of a mandibular second molar with distal caries. The method involved 56 endodontically-treated molars that were restored with CAD/CAM glass-ceramic onlays after a single-visit root canal treatment. The effects were evaluated after 6, 12, 18 and 24 months by one-experienced clinicians in accordance with the modified USPHS criteria at baseline. The follow-up after two years showed teeth recovery. Satisfactory effects were observed in marginal adaptation, tooth integrity, color match, surface roughness, gingival inflammation, retention, and proximal contact. There were notable failures in three cases: two onlays were extracted and one was fractured. In conclusion, using CAD/CAM glass-ceramic onlays is an effective treatment for the restoration of permanent molars with serious caries.","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132311997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of a Serious Atrophy of the Upper Jaw After a Regenerative Failure with One Phase Titanium Subperiosteal Implant","authors":"Dent Adv Res","doi":"10.29011/2574-7347.100067","DOIUrl":"https://doi.org/10.29011/2574-7347.100067","url":null,"abstract":"Subperiosteal implants have been introduced in 1941 by Gustav Dahl and revisited in 1946 by Norman Goldberg and Aaron Gerschkoff and are the customized surgical devices in subperiosteal implantology Later numerous authors including Linkow LI [1-4], Cranin AN [5-9], Weiss CM [10-11], Bodine RL, Yanase RT [12], Bodine A [12], Chanavaz M., Maurice James Fagan, Robert A. James [13], Martians [14], E. Belotti [15] have contributed to the evolution of the technique with improvements in the design [5,16,17], in the study of the bone-implant interface [11,18], in the microbiological aspects [19], epithelial attack [20-22] and statistical studies [15,23]. The implants have been validated for efficacy, safety and survival by numerous longitudinal, prospective and retrospective studies, long-term follow-up [24-30]. The most relevant retrospective study was provided by Moore and Hansen in an 18-year temporal analysis [31]. The most significant prospective study was performed by Bodine, Yanase, Bodine [32] with a 41-year investigation [23]. Subperiosteal implant, among the techniques available and indicated for the treatment of immediate loading advanced atrophies (Cawood and Howell class VI), is the implant that benefits the longest prospective study These implants are indicated for the treatment with immediate loading of both total and partial severe and advanced bone atrophies [10] and are alternative or priority to onlay and inlay grafting procedures, to the Lefort 1 osteotomy with interpositional graft, to the intra-extra sinus zygomatic implants (Quad / Hibrid Zygoma).","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114927908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orthodontic Treatment Requirements and Approaches in Children with Bleeding Disorders","authors":"E. Güler, K. Kavaklı, B. Zulfikar, Ş. Tanboğa","doi":"10.29011/2574-7347.100070","DOIUrl":"https://doi.org/10.29011/2574-7347.100070","url":null,"abstract":"Aim: In history, orthodontic treatments were avoided in haemophiliac patients. However, since orthodontic treatment is consistent with general health and is a necessity for medically compromised patients, it is not a contradiction anymore. The purpose of this study is to investigate the orthodontic treatment needs of haemophiliac children in Turkey, to determine the approaches and fears of orthodontic treatment among parents and to create a treatment protocol to inform parents and doctors. Material and Method: The study is designed as a cross-sectional study comparing oral health and malocclusion index of haemophiliac patients with matched healthy subjects. Study and control groups included 58 children from five to fifteen years old. DMFT and dmft indexes were used for caries index; ICON and IOTN indexes and questionnaires were used to evaluate the need for orthodontic treatment. Results: dmft averages of the study group were statistically significantly higher than the control group. The ICON and IOTN averages of the study group were statistically significantly higher than the control group. Conclusions: Parents need to be informed more about the possibility that haemophiliac children may have orthodontic treatment. Preventive and interceptive orthodontic treatments performed in the early period are of great importance. Paediatric dentists must have the knowledge for treatment of these patients.","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126980132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Denture Plaque Management of Denture-Related Stomatitis","authors":"P. Bars, F. Jordana, A. Kouadio","doi":"10.29011/2574-7347.100073","DOIUrl":"https://doi.org/10.29011/2574-7347.100073","url":null,"abstract":"The regular use of a removable prosthesis, in particular in fully edentulous aging subjects, constitutes, within the oral cavity, support for Denture Plaque (DP), promoting the growth of a candidosic population that often leads to Denture Stomatitis (DS). This pathology is an infectious disease of multifactorial etiology. The purpose of this article is to review management approaches for DS at different levels: (1) lifestyle, (2) drug addiction, and (3) several general diseases such as diabetes mellitus, cardiovascular, respiratory and digestive diseases, and immune deficiencies that favor the development of DS. Moreover, caries, periodontal diseases, a removable prosthesis that is poorly adapted or worn continuously, poor oral hygiene, and reduced salivary flow can promote Candida ’s ability to colonize removable dentures. In the presence of a removable prosthesis, these parameters can influence homeostasis between the host and yeast, promoting the transition of Candida spp. from commensal to pathogenic. The objectives of this review are, therefore, to analyze the influence of these different parameters on the balance of DP in oral ecology, and to explore the mechanisms and means for limiting its drift toward dysbiosis.","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129865865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mouthguards Shielding the Athletic Smile: A Mini-Review","authors":"Nishita Rana, Namita Singh, Gurdeep Singh","doi":"10.29011/2574-7347.100080","DOIUrl":"https://doi.org/10.29011/2574-7347.100080","url":null,"abstract":"Background: The contemporary world is becoming fitness and health conscious; consequently, an increasing number of individuals are indulging in sports and associated activities. Nonetheless, involvement in sports increases the risk of severe dental and maxillofacial injuries, affecting the individual’s quality of life. The most effective way to prevent such injuries is to wear a properly fitted mouthguard, an intraoral device worn over the teeth. Aim: This article aims to shed light on mouthguards, their types, characteristics, current fabrication and their significance in preventing oro-facial injuries in sports. Conclusion: Sports-related dental traumas and other athletic activities establish a linkage between sports and dentistry. Thus, Mouthguards have proven to be an integral component in injury prevention.","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115924720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Behavior of MDPC-23 Cells Modulated by DSPP","authors":"Yu-Hsuan Chen, Shu-Feng Chuang, H. Ritchie","doi":"10.29011/2574-7347.100081","DOIUrl":"https://doi.org/10.29011/2574-7347.100081","url":null,"abstract":"Phosphophoryn (PP) and Dentin Sialoprotein (DSP) are two of the most abundant dentin matrix non-collagenous proteins. These two proteins are derived from Dentin Sialophosphoprotein (DSPP) precursor protein cleavage by DMP1 protease. PP was well established as a nucleator to initiate dentin mineralization. The expression of DSPP precursor protein was reported to be required for normal odontoblast lineage differentiation. DSPP protein was also reported to modulate cell migration, cell proliferation and differentiation, leading to dentin formation. To further understand the role of DSPP in odontoblast lineage, we used MDPC23 cells to examine the mineralization process and the effects of DSPP on this process. MDPC23 cell line is an odontoblast-like cells, which exhibits unique features of dental pulp stem cells such as high alkaline phosphatase activity and expression of odontoblast markers: DSP and PP. MDPC23 cells were cultured in Mineralization Medium (MM) containing mineral inducing molecules (i.e., 100 μg//ml ascorbic acid, 10 mM β-glycerol phosphate and 10 nM dexamethasone) to examine MM effects on the cell growth and mineral deposition. Recombinant DSPP protein was used to test its effects on dental pulp cell growth and mineralization. We found that MDPC23 cells cultured with mineralization medium, proliferated slowly and spread widely at 4d. However, MDPC 23 cells in MM group, shrank and gradually detached from the well surface at 6d. Strong mineral deposition was detected with Alizarin Red staining at 7d. In the presence of recombinant DSPP protein (recDSPP), MDPC23 cells cultured with mineralization medium, also proliferated slowly, spread widely but remained vital from 4d, 6d, 7d, 8d, 9d, 10d, 12d through 18d and 20d. Strong mineral deposition was detected with Alizarin Red staining at 18d and 20d. Thus under the combined MM and recDSPP treatment, MDPC23 cells maintained the cell vitality and delayed the mineralization process. This study lent support that DSPP is required for maintaining normal odontoblast lineage.","PeriodicalId":381715,"journal":{"name":"Dentistry: Advanced Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124355542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}