Nephrology Times最新文献_第7页

Novel Technique Prevents Contrast-Induced Acute Kidney Injury 新技术预防造影剂引起的急性肾损伤

Nephrology Times Pub Date : 2011-09-01 DOI: 10.1097/01.NEP.0000406712.96753.DA

F. Lowry

{"title":"Novel Technique Prevents Contrast-Induced Acute Kidney Injury","authors":"F. Lowry","doi":"10.1097/01.NEP.0000406712.96753.DA","DOIUrl":"https://doi.org/10.1097/01.NEP.0000406712.96753.DA","url":null,"abstract":"RenalGuard, a new physiologic therapy that washes contrast through the kidney rapidly, was superior to sodium bicarbonate and Nacetylcysteine (NAC) in preventing contrast-induced acute kidney injury in high-risk patients. These results came from the randomized, multicenter, investigator-driven Renal Insuffi ciency After Contrast Media Administration Trial II (REMEDIAL II), which was conducted in Italy and published online before print by Circulation. “The results of the REMEDIAL II trial support the concept that the most important strategy to prevent contrastinduced acute kidney injury is an optimal increase in the urine fl ow rate without inducing fl uid imbalance,” said lead author Carlo Briguori, MD, PhD, Chief of the Laboratory of Interventional Cardiology at Clinica Mediterranea (Mediterranean Clinic) in Naples, Italy, in an interview. “This effect is reached by the RenalGuard system in almost all patients. By contrast, it is hardly reached by standard hydration.” In REMEDIAL II, which was carried out at four interventional cardiology centers in Italy between January 2009 and December 2010, 294 patients were randomized to receive sodium bicarbonate solution plus NAC at a high dose (the control group), or hydration with saline and NAC at a high dose plus a low dose of furosemide controlled by the RenalGuard system. Two patients, one from each group, did not undergo scheduled treatment, leaving 146 patients in each group for the fi nal analysis.","PeriodicalId":380758,"journal":{"name":"Nephrology Times","volume":"137 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122048089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hurricane Irene: Coordinated Response Prevents Dialysis Disruption 飓风艾琳:协调应对防止透析中断

Nephrology Times Pub Date : 2011-09-01 DOI: 10.1097/01.NEP.0000406707.22303.6e

M. Hogan

{"title":"Hurricane Irene: Coordinated Response Prevents Dialysis Disruption","authors":"M. Hogan","doi":"10.1097/01.NEP.0000406707.22303.6e","DOIUrl":"https://doi.org/10.1097/01.NEP.0000406707.22303.6e","url":null,"abstract":"As Hurricane Irene headed for the East Coast of the United States, the dialysis community was prepared for the worst. These efforts, coupled with changes in storm strength and the weekend timing of landfall, largely had their desired effect, with most units from North Carolina to Maine up, running, and dialyzing patients the day after the storm. “Irene was a large, powerful storm that impacted millions of people along the Eastern Seaboard, many of whom had never experienced the direct effects of a hurricane,” wrote Seth Holloway, MPH, CPH, Emergency Management Specialist for the Kidney Community Emergency Response (KCER) Coalition, in an e-mail message. “The kidney community, through preparation, collaboration, and coordinated response, greatly diminished the storm’s potential impacts to the dialysis and transplant populations, undoubtedly saving many lives.” Marathon and a Sprint The KCER Coalition, which was formed in January 2006, includes representatives of kidney patient and professional organizations, clinicians, dialysis facilities, End-Stage Renal Disease (ESRD) Networks, state emergency and survey representatives, and federal agencies. It facilitates timely and effi cient disaster preparedness, response, and recovery for the kidney community. Hurricane Irene: Coordinated Response Prevents Dialysis Disruption","PeriodicalId":380758,"journal":{"name":"Nephrology Times","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127123708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Mixed Bag of Posttransplant HLA Monitoring 移植后HLA监测的混合袋

Nephrology Times Pub Date : 2011-08-01 DOI: 10.1097/01.NEP.0000405323.96362.4F

M. Kamgar, S. Bunnapradist

引用次数: 0

Tacrolimus-MMF Immunosuppression Offers Best Results in Randomized Trial 他克莫司- mmf免疫抑制在随机试验中提供最佳效果

Nephrology Times Pub Date : 2011-08-01 DOI: 10.1097/01.NEP.0000405318.65868.34

M. Hogan

引用次数: 0

Nephrology Consultations Come Sooner, but Survival Rates Donʼt Get Much Better 肾脏病咨询来得更快，但存活率并没有提高多少

Nephrology Times Pub Date : 2011-08-01 DOI: 10.1097/01.NEP.0000405322.88739.9C

M. Hogan

引用次数: 0

In Elective-Start Patients, PD and HD Offer Similar Survival 在选择性启动患者中，PD和HD的生存率相似

Nephrology Times Pub Date : 2011-08-01 DOI: 10.1097/01.NEP.0000405320.11610.BA

F. Lowry

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Sudden Cardiac Death & Dialysis: Target Risk Factors 心脏性猝死与透析:目标危险因素

Nephrology Times Pub Date : 2011-08-01 DOI: 10.1097/01.NEP.0000405319.03987.C3

V. Bansal

引用次数: 0

Ambulatory Blood-Pressure Monitoring Better Predictor of CV and Renal Risk in CKD 动态血压监测能更好地预测CKD患者CV和肾脏风险

Nephrology Times Pub Date : 2011-07-01 DOI: 10.1097/01.NEP.0000403742.22708.BD

F. Lowry

引用次数: 0

B-Cell-Depleting Agents: The Chicken and the Egg b细胞消耗剂:鸡和蛋

Nephrology Times Pub Date : 2011-07-01 DOI: 10.1097/01.NEP.0000403738.99836.2D

A. Salama

引用次数: 0

For African-American Kidney Donors, Genetic Variants Linked to Graft Survival 对于非裔美国肾脏捐赠者，基因变异与移植物存活有关

Nephrology Times Pub Date : 2011-06-01 DOI: 10.1097/01.nep.0000399779.93032.76

M. Hogan

{"title":"For African-American Kidney Donors, Genetic Variants Linked to Graft Survival","authors":"M. Hogan","doi":"10.1097/01.nep.0000399779.93032.76","DOIUrl":"https://doi.org/10.1097/01.nep.0000399779.93032.76","url":null,"abstract":"Deceased-donor kidneys from African-Americans with two particular gene variants failed much more quickly than those from African-Americans without the two variants, found a single-center study published in the American Journal of Transplantation (2011;11:1025-1030). These results extend to transplantation the previously reported relationship between the apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy risk in this population. “The APOL1 genetic association with nondiabetic kidney failure in African-Americans is among—if not the—most powerful genetic association in any common disease,” said senior author Barry I. Freedman, MD, Professor and Chief of the Section on Nephrology at Wake Forest School of Medicine, in a phone interview. “It fully explains the excess risk of nondiabetic kidney failure in blacks compared with whites in the United States and accounts for 40 percent or so of all African-Americans on dialysis. That’s very impressive, and there are no other genes in the renal literature of this effect. “If a kidney is donated by an African-American, it does not statistically function for as long as a kidney donated by a white, so one of the questions we had was, could this have anything to do with APOL1?” Finding this relationship between APOL1 risk variants in the donor and graft survival in the recipient could mean big changes for kidney transplantation, but not just yet. “These results have to be For African-American Kidney Donors, Genetic Variants Linked to Graft Survival","PeriodicalId":380758,"journal":{"name":"Nephrology Times","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116065019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0