Batna Journal of Medical Sciences (BJMS)最新文献

筛选
英文 中文
Study of mercury release in dental amalgam wearers by measuring salivary and urinary mercury 通过测量唾液和尿液中的汞含量来研究牙科汞合金佩戴者的汞释放
Batna Journal of Medical Sciences (BJMS) Pub Date : 2023-04-22 DOI: 10.48087/bjmsoa.2023.10105
K. Sobhi, M. Azzouz, Saliha Magherbi, B. Alamir
{"title":"Study of mercury release in dental amalgam wearers by measuring salivary and urinary mercury","authors":"K. Sobhi, M. Azzouz, Saliha Magherbi, B. Alamir","doi":"10.48087/bjmsoa.2023.10105","DOIUrl":"https://doi.org/10.48087/bjmsoa.2023.10105","url":null,"abstract":"Background. Mercury amalgam remains the most effective and least expensive dental filling material. Mercury is considered by the World Health Organization (WHO) as one of the ten chemicals or groups of chemicals that are extremely concerning for public health. The aim of our study is to assess exposure to mercury from dental amalgams through the measurement of salivary and urinary mercury. Population and methods. This is a prospective, analytical study carried out at the National Toxicology Center of Algiers during the year 2004. The study included 48 subjects with dental amalgams and 12 subjects without amalgams. Mercury levels in saliva and urine were measured by cold vapor atomic absorption spectrometry using the \"Flow Inject Mercury System\". Results. Compared to other studies, the urinary mercury values in our study are relatively high. This observation is also true for our controls. For salivary values, our subjects have levels (after chewing) that remain within the same range. The comparison of urinary and salivary means shows a significant difference between subjects with three or more amalgams and controls. There is also a significant correlation between the number of fillings and salivary concentrations. Among all amalgam bearers, there is no significant correlation between urinary and salivary concentrations. Elevated levels were noted in our controls compared to foreign studies, indicating probable general exposure (food, atmosphere, etc.). Conclusion. There is a real exposure to mercury from dental amalgams, but is this exposure harmful to the health of the bearers? This risk remains \"acceptable\" as long as we stay below the accepted limits. It is necessary to protect at-risk groups (pregnant and breastfeeding women, children, and adolescents) from this exposure.","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131735872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of acute renal failure in infants: a seven-year multicenter experience. 婴儿急性肾功能衰竭的管理:7年多中心经验。
Batna Journal of Medical Sciences (BJMS) Pub Date : 2023-04-22 DOI: 10.48087/bjmsoa.2023.10101
Soumia Missoum, M. Lahmar, Ghalia Khellaf, Haithem Bourenane, Nasreddine Sersoub
{"title":"Management of acute renal failure in infants: a seven-year multicenter experience.","authors":"Soumia Missoum, M. Lahmar, Ghalia Khellaf, Haithem Bourenane, Nasreddine Sersoub","doi":"10.48087/bjmsoa.2023.10101","DOIUrl":"https://doi.org/10.48087/bjmsoa.2023.10101","url":null,"abstract":"Background. An infant with acute kidney injury (AKI) represents a technical challenge with respect to vascular access. Acute peritoneal dialysis (PD) is often the only possible treatment modality. Patients and methods. Over a period of 7 years (2014 -2021), the outcome of acute PD was studied in 56 infants (38 boys) with AKI, aged 6 hours to 24 months, at 3 tertiary care centers of a teaching hospital in Algeria. Results. Acute tubular necrosis (58.9%) was the most common cause of AKI, followed by hemolytic uremic syndrome (23.2 %). Acute PD was highly effective in lowering retention markers (p < 0.0001). The reduction of blood urea greater than 11% after 10 cycles of PD would be the first sign of good evolution followed by that of serum creatinine at 10% after 15 cycles (p < 0.0001). Hypokaliemia was the most common complication (46.4%). Overall mortality was 23.2 %. The risk of mortality by multi-variate analysis was higher with the Severity of AKI and when patients were anuric (p < 0.0001), septicemia (p < 0.0001), or decompensated congenital heart disease (p < 0.001) The survivors did not differ from those who died with respect to age, sex or weight when acute PD was initiated. The average time to renal function recovery was between 72 hours and 12 days. Conclusion. Acute PD is an appropriate treatment choice for infants with AKI. The reduction of blood urea after 10 cycles of PD is a good predictor of evolution.","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114920487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of oral pain in patients with cavum cancer treated with cancer chemotherapy 腔癌化疗后口腔疼痛的评价
Batna Journal of Medical Sciences (BJMS) Pub Date : 2023-04-22 DOI: 10.48087/bjmsoa.2023.10106
Nadia Djafar, Razika Salah Mars, Mounir Zaghez
{"title":"Evaluation of oral pain in patients with cavum cancer treated with cancer chemotherapy","authors":"Nadia Djafar, Razika Salah Mars, Mounir Zaghez","doi":"10.48087/bjmsoa.2023.10106","DOIUrl":"https://doi.org/10.48087/bjmsoa.2023.10106","url":null,"abstract":"Objective. This study aims to evaluate oral pain experienced by patients with nasopharyngeal cancer after administration of anticancer chemotherapy protocol. Materials and Methods. This is a prospective study conducted on patients with nasopharyngeal cancer treated with chemotherapy at the Anti-Cancer Center (CAC) in Annaba over a period of 2 years. Results. Out of the 80 patients recruited in our study, it was found that oral pain was only felt at the mucosal level, and there was a statistically significant relationship between pain and the intensity of mucosal lesion (mucositis) (p = 0.001). Pain was experienced by 36 patients (45%, 95% CI); with a grade 1 (mild discomfort) intensity in 19 patients (52.78%), grade 2 (mild pain) in 15 patients (41.67%) and grade 3 (moderate pain) in 2 patients (5.5%). Conclusion. In order to improve the quality of life of cancer patients, determining the incidence and intensity of oral pain is essential for all patients treated with chemotherapy in order to guide therapeutic choices and evaluate the effectiveness of analgesic treatments.","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126960848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perception of caesarean section among pregnant women treated in some hospitals in Kinshasa 在金沙萨一些医院接受治疗的孕妇对剖腹产的认识
Batna Journal of Medical Sciences (BJMS) Pub Date : 2023-04-22 DOI: 10.48087/bjmsoa.2023.10107
J. Mwenzi, Ruth Bukabau Babuya, Hera Mbo Mokuba, Mutunga Nassy, Omar Paypay
{"title":"Perception of caesarean section among pregnant women treated in some hospitals in Kinshasa","authors":"J. Mwenzi, Ruth Bukabau Babuya, Hera Mbo Mokuba, Mutunga Nassy, Omar Paypay","doi":"10.48087/bjmsoa.2023.10107","DOIUrl":"https://doi.org/10.48087/bjmsoa.2023.10107","url":null,"abstract":"Objective. The objective of this article is to evaluate the perception of caesarean section among pregnant women treated in some hospitals in the city of Kinshasa. Materials and Methods. A survey questionnaire (consisting of 11 questions) was administered to a non-probabilistic sample of 110 pregnant women undergoing antenatal consultations at the Cliniques Universitaires de Kinshasa and the Centre Hospitalier du Mont-Amba. Results. The results indicate that pregnant women in the study have a positive perception of caesarean section. This positive perception is reflected in their tolerance and acceptance of the planned procedure. The substudy women were, however, afraid of caesarean sections. Finally, they have more objective than subjective knowledge of Caesarean section. Conclusion. Our study subjects consider Caesarean section as a compulsory medical intervention in case of certain complications. Therefore, they do not find any disadvantage in giving birth by this way.","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126850824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemio-clinical aspects of fractures of the long bones of the lower limbs at the University Hospital Joseph Ravoahangy Andrianavalona Joseph Ravoahangy Andrianavalona大学医院下肢长骨骨折的流行病学-临床方面
Batna Journal of Medical Sciences (BJMS) Pub Date : 2023-04-22 DOI: 10.48087/bjmsoa.2023.10102
Hanitrankasitrahana Amboarasarobidy Rohimpitiavana, Mirana Rosette Soanirina, Ismael Andrianina Razaka, A. Rabemazava, G. D. Solofomalala, H. Razafimahandry
{"title":"Epidemio-clinical aspects of fractures of the long bones of the lower limbs at the University Hospital Joseph Ravoahangy Andrianavalona","authors":"Hanitrankasitrahana Amboarasarobidy Rohimpitiavana, Mirana Rosette Soanirina, Ismael Andrianina Razaka, A. Rabemazava, G. D. Solofomalala, H. Razafimahandry","doi":"10.48087/bjmsoa.2023.10102","DOIUrl":"https://doi.org/10.48087/bjmsoa.2023.10102","url":null,"abstract":"Background. Fractures of the long bones of the lower limbs are frequently encountered in traumatology setting. Aim. Our objective was to describe the epidemiological and clinical aspects of fractures of the long bones of the lower limbs screwed and treated in the Orthopaedic and Trauma Department of the University Hospital of Joseph Ravoahangy Andrianavalona. Methods. This is a descriptive retrospective study from January to December 2019 of fractures of the long bones of the lower limbs admitted to the department. Results. Three hundred sixty-one patients were studied. The male gender predominated (Sex ratio =1.95). The age group between 15 and 30 was the most affected (38.78%). Workers were the most affected (29.09%). Road accidents were the most frequent etiology (73.13%). Pain was constant. The closed fractures of the 2 leg bones were the most observed (49.03%). Conclusion. Fractures of the long bones of the lower limbs concern all professional strata. The resurgence of public road accidents requires preventive measures.","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114699251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of imaging in the diagnosis of acute appendicitis. Report of 273 patients 影像学在急性阑尾炎诊断中的作用。273例患者报告
Batna Journal of Medical Sciences (BJMS) Pub Date : 2023-04-22 DOI: 10.48087/bjmsoa.2023.10104
W. Ferjaoui, S. Omrani, M. Hajri, H. Mestiri, R. Bayar
{"title":"The role of imaging in the diagnosis of acute appendicitis. Report of 273 patients","authors":"W. Ferjaoui, S. Omrani, M. Hajri, H. Mestiri, R. Bayar","doi":"10.48087/bjmsoa.2023.10104","DOIUrl":"https://doi.org/10.48087/bjmsoa.2023.10104","url":null,"abstract":"Background. The clinical diagnosis of acute appendicitis is not always obvious. The rate of “unnecessary” interventions remains rather high. Imaging therefore plays an important role in the diagnosis of this surgical emergency, particularly in atypical cases. The aim of this work is to elucidate the role of imaging in the diagnosis of this pathology. Materials and methods. This is a retrospective study that was conducted between January 2013 and December 2019. Different elements were considered, functional signs, physical examination data, biological and radiological examinations, intraoperative findings, and pathological results. The certainty of the diagnosis of acute appendicitis was established on the result of the anatomopathological examination of the surgical specimen, or failing that, on an evocative intraoperative aspect. Results. A number of 273 patients was included. Among our patients there were 142 men and 131 women. Average age was 32 years old. Right iliac fossa pain was the main complaining sign, found in 89.7% of cases. Ultrasound was performed in 217 patients confirming the diagnosis in 77% of cases. CT was performed in 134 patients, confirming the diagnosis in 84.3% of cases. A total of 227 patients were operated, i.e., 83.2%. The rest were discharged after monitoring in the department. Accuracy of ultrasound was 71.4%. Diagnostic accuracy of CT was 82.1%. Conclusion. Clinical presentation is often polymorphic. Imaging is often necessary. First-line abdominal ultrasound is preferred. Abdominal CT scan is to be requested as first line imaging modality in the elderly or obese subject.","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129277273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generic Imatinib Mesylate as first line treatment of chronic myeloid leukemia 甲磺酸伊马替尼作为慢性髓系白血病的一线治疗
Batna Journal of Medical Sciences (BJMS) Pub Date : 2023-04-22 DOI: 10.48087/bjmsoa.2023.10103
B. Benzineb, Naima Melsi, M. Bekadja, B. Entasoltan, Nawel Siali, Z. Zouaoui, K. Taibi, D. Saidi, H. Touhami, Toufik Yachekour, A. Bachiri, N. Mehalhal
{"title":"Generic Imatinib Mesylate as first line treatment of chronic myeloid leukemia","authors":"B. Benzineb, Naima Melsi, M. Bekadja, B. Entasoltan, Nawel Siali, Z. Zouaoui, K. Taibi, D. Saidi, H. Touhami, Toufik Yachekour, A. Bachiri, N. Mehalhal","doi":"10.48087/bjmsoa.2023.10103","DOIUrl":"https://doi.org/10.48087/bjmsoa.2023.10103","url":null,"abstract":"Background. In order to reduce the cost of treating diseases, governments tend to use generic drugs, as in the case of chronic myeloid leukemia (CML). The aim of this study is to evaluate the therapeutic efficacy of an Imatinib Mesylate (IM) generic drug as first line treatment of CML. Patients and methods. A retrospective (01-01-2017 to 31-12-2018) multicenter study, related to patients with CML in the chronic phase and treated with the IM generic as a first line therapy. Results. We collected data of 392 patients. Median age was 48 (16-85) years. In 43% of cases, treatment was stopped following resistance or intolerance, of which 2.8% of cases progressed to an advanced phase. 2.6% of patients lost their molecular and hematological response. Overall survival (OS) was 76.4%. OS was poor in the high Sokal-score group (69%) compared to the low (73%) and intermediate (81.4%) risk groups (p: 0.01). Conclusion. The choice of the a generic IM as first-line treatment of CML makes it possible to obtain a satisfactory response rate and a good safety profile.","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127950179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facteurs prédictifs de l’issue de l’accouchement sur utérus cicatriciel au service de gynécologie obstétrique EHS Batna, Algérie 阿尔及利亚巴特纳EHS产科妇科瘢痕子宫分娩结果的预测因素
Batna Journal of Medical Sciences (BJMS) Pub Date : 2022-12-27 DOI: 10.48087/bjmsoa.2022.9206
{"title":"Facteurs prédictifs de l’issue de l’accouchement sur utérus cicatriciel au service de gynécologie obstétrique EHS Batna, Algérie","authors":"","doi":"10.48087/bjmsoa.2022.9206","DOIUrl":"https://doi.org/10.48087/bjmsoa.2022.9206","url":null,"abstract":"Introduction. La pratique de césariennes est en ‎augmentation constante dans le monde, soulevant la ‎problématique de la gestion des femmes enceintes ‎ayant un utérus cicatriciel. L’objectif de notre travail ‎était d’identifier les facteurs significativement ‎associés au succès de l’épreuve utérine au sein de ‎notre service, afin de réaliser une sélection ‎rigoureuse des candidates à la tentative de voie ‎basse. Méthodes. Nous avons mené une étude ‎épidémiologique descriptive, rétrospective, mono ‎centrique au niveau de l'EHS mère – enfant Batna du ‎‎1er janvier 2018 au 31 décembre 2019 ayant ‎intéressé les femmees porteuses d’un utérus ‎cicatriciel d’origine obstétricale avec un âge de ‎grossesse supérieur à 22 SA. Résultats. Au cours de ‎notre étude nous avons recensé 3002 ‎accouchements sur utérus cicatriciel. Le taux de ‎tentatives de voie basse après césarienne était de ‎‎46,84 % avec un taux de succès de 89,19 %. Les ‎principaux facteurs qui favorisent le succès de la ‎tentative de voie basse après césarienne étaient : un ‎antécédent d’accouchement par voie vaginale après ‎la césarienne (p<0,001), la multiparité (p=0,0002), ‎une césarienne précédente pour présentation ‎podalique (p<0,001), un intervalle inter génésique ‎de 12 mois et plus (p<0,001), des conditions locales ‎favorables (dilatation du col supérieure à 4 cm ; ‎p=0,02 et la rupture artificielle des membranes ; ‎p=0,03). Les facteurs qui défavorisent le succès de la ‎TVBAC étaient : un antécédent de césarienne pour ‎stagnation ou non-engagement à dilatation complète ‎‎(p<0,001), un terme d’accouchement supérieur à 40 ‎SA (p=0,002), un poids de naissance supérieur à ‎‎4000 g (p<0,001). Les facteurs qui ne semblent pas ‎influencer l’issue de l’épreuve utérine étaient : l’âge ‎maternel, l’âge de réalisation de la première ‎césarienne, la présence de pathologies maternelles ‎et la réalisation de radiopelvimétrie. Conclusion. Les ‎facteurs de succès et d’échec d’une TVBAC sur ‎utérus cicatriciel sont importants à relever pour les ‎décisions ultérieures de la voie d’accouchement, la ‎situation obstétricale doit être soigneusement ‎évaluée et en cas de doute, faire appel à une décision ‎collégiale.‎","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117044706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Etude rétrospective des cancers rénaux dans le service d’oncologie médicale CHU Annaba (2008-2016). CHU Annaba医学肿瘤科肾癌回顾性研究(2008-2016)。
Batna Journal of Medical Sciences (BJMS) Pub Date : 2022-12-27 DOI: 10.48087/bjmsoa.2022.9202
{"title":"Etude rétrospective des cancers rénaux dans le service d’oncologie médicale CHU Annaba (2008-2016).","authors":"","doi":"10.48087/bjmsoa.2022.9202","DOIUrl":"https://doi.org/10.48087/bjmsoa.2022.9202","url":null,"abstract":"Objectif. Notre étude avait pour objectif de dégager ‎le profil épidémiologique, clinique, histo-‎pathologique, thérapeutique et évolutif des cancers ‎rénaux dans le centre anti cancer Annaba Algérie. ‎Patients et méthodes. Etude rétrospective incluant ‎‎50 cas de cancers rénaux traités au sein des services ‎d’oncologie médicale CHU Annaba entre janvier ‎‎2008 et octobre 2016. Résultats. Il s’agissait de 30 ‎hommes et de 20 femmes. L’âge moyen de ‎découverte était de 51 ans (extrêmes : 23-79 ans). ‎Le facteur de risque le plus fréquemment observé ‎était le tabagisme (58 %) suivi par l’hypertension ‎artérielle (40 %). La douleur lombaire était le signe ‎révélateur le plus fréquemment noté chez 48 % des ‎patients. Le diagnostic a été basé sur la tomodensito-‎métrie chez 100 % des patients. 54 % des tumeurs ‎étaient localisées dans le rein droit. 42 % des ‎patients étaient de groupe pronostique ‎intermédiaire. La néphrectomie était pratiquée chez ‎‎90 % des patients. Le type histologique prédominant ‎était le carcinome rénal à cellule claire (70 %), le ‎grade de Fuhrman prédominant (grade 2 et 3) ‎‎(36%). 86 % des patients étaient métastatique. ‎‎37.2 % des patients avaient 2 sites métastatiques. ‎Parmi les 50 malades, 43 avaient reçu un traitement ‎systémique versus 7 une surveillance. En 1ère ligne ‎un inhibiteur de tyrosine kinase a était administré ‎chez 41 malades (sunitinib (35pts) /sorafénib ‎‎(6pts)), chimiothérapie associée à un anti ‎angiogenèse chez deux malades. Sunitinib schéma ‎‎(4/2) a était utilisé chez 19 pts versus (2/1) chez 14 ‎pts, une réduction de dose a été pratiquée chez 18 ‎pts. Les effets secondaires les plus rencontrés ont ‎était l’asthénie (14 tous grades/09 grade 3et 4), ‎syndrome main/pied (08 tous grades/05 grades 3 et ‎‎4), mucite (11 pts), neutropénie (8 pts), ‎hypertension artérielle (5 pts), hypothyroïdie (5 pts). ‎Neuf malades avaient reçu une 2ème ligne de ‎traitement, un malade une 3ème ligne thérapeutique. ‎L’évolution des malades était : 14 % ‎‎(surveillance) ,4 % (RC) ,14 % (RP), (MP) ,60 % ‎décédés. La médiane de survie globale était de 38,5 ‎mois avec des extrêmes de 3 et de 74 mois. ‎Conclusion. Le cancer rénal dans notre population ‎était rencontré chez le sujet de la cinquième ‎décennie avec prédominance masculine, la ‎symptomatologie clinique était polymorphe dominée ‎par des signes urologiques, la majorité des patients ‎ont été métastatiques. Presque la totalité avait ‎bénéficié d’une néphrectomie. Les inhibiteurs de ‎tyrosine kinase ont été le traitement de choix de ‎première ligne chez la majorité des malades avec ‎une amélioration significative de la survie globale ‎mais au prix d’une toxicité importante.‎","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121270253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aspect épidémio-cliniques des leishmanioses cutanées dans la région de l’est algérien. Bilan de 3 ans (2018-2020). 阿尔及利亚东部地区皮肤利什曼病的流行临床方面。3年回顾(2018-2020年)。
Batna Journal of Medical Sciences (BJMS) Pub Date : 2022-12-27 DOI: 10.48087/bjmsoa.2022.9203
{"title":"Aspect épidémio-cliniques des leishmanioses cutanées dans la région de l’est algérien. Bilan de 3 ans (2018-2020).","authors":"","doi":"10.48087/bjmsoa.2022.9203","DOIUrl":"https://doi.org/10.48087/bjmsoa.2022.9203","url":null,"abstract":"Introduction : Les maladies à transmission ‎vectorielle (MTV) ont connu une explosion ces ‎dernières années en Algérie. Le tableau est ‎essentiellement dominé par la leishmaniose cutanée ‎‎(LC), qui représente un problème de santé publique ‎en Algérie. Le but de notre travail est de décrire le ‎profil épidémio - clinique des cas de leishmaniose ‎cutanée diagnostiqués dans la région de l’est ‎algérien. Matériels et méthodes : Nous avons ‎effectué une étude basée sur l'exploitation des ‎dossiers et l’observation des malades ayant présenté ‎une \u0000leishmaniose cutanée entre janvier 2018 et ‎décembre 2020. Résultats : Nous avons colligé 138 ‎cas de leishmaniose cutanée. L’âge moyen des ‎patients était de 30,6 ans avec des extrêmes de 3 ‎mois et de 80 ans. Le sex-ratio était de 2.94 H/F. La ‎durée d’évolution moyenne des lésions était de 2,85 ‎mois avec des \u0000extrêmes de 10 jours à 24 mois. Une prépondérance ‎automnale était notée avec 57 cas (41,3 %). Le ‎nombre annuel moyen des cas était de 46 cas. ‎L’aspect clinique le plus fréquent était celui de ‎lésions ulcéro-croûteuses, 104 cas (75,36%). On a ‎noté la prédilection du siège au visage 52 cas ‎‎(37,68%). Le diagnostic était évoqué cliniquement et ‎confirmé par l’examen parasitologique direct. ‎Conclusion : La leishmaniose cutanée continue à ‎poser un vrai problème de santé publique dans ‎notre pays. L’Algérie constitue actuellement le pays ‎le plus touché dans les pays du pourtour du bassin ‎méditerranéen ; ce qui doit inciter à multiplier et à ‎renforcer les mesures prophylactiques à travers la ‎lutte contre les réservoirs et les vecteurs du parasite. ‎Une optimisation thérapeutique, par le suivi de ‎protocoles standardisés et par un référentiel ‎consensuel reste nécessaire.‎","PeriodicalId":377795,"journal":{"name":"Batna Journal of Medical Sciences (BJMS)","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116924492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书