Journal of Advances in Internal Medicine最新文献

Anaphylactic reaction after intravenous injection of ketorolac for colicky pain: a case report and literature review 静脉注射酮咯酸治疗绞痛后的过敏反应1例报告并文献复习

Journal of Advances in Internal Medicine Pub Date : 2023-07-15 DOI: 10.3126/jaim.v12i1.56679

Susmin Karki, G. S. Shrestha, S. Yadav, Ravi Shah, Saurav Agrawal, Asmita Parajuli

引用次数: 0

Marburgvirus: A Global Virus, not just an African problem 马尔堡病毒:一种全球性病毒，而不仅仅是非洲的问题

Journal of Advances in Internal Medicine Pub Date : 2023-07-15 DOI: 10.3126/jaim.v12i1.56682

J. Robinson, Indrajit Banerjee, Alexandra Leclézio

引用次数: 0

Clinical Profile of End Stage Renal Disease Patients Undergoing Hemodialysis in a Tertiary Care Hospital of Nepal 尼泊尔一家三级医院接受血液透析的终末期肾病患者的临床概况

Journal of Advances in Internal Medicine Pub Date : 2023-07-15 DOI: 10.3126/jaim.v12i1.56678

R. Mandal, Rajan Pande, K. Yadav, Kuldip Goit

{"title":"Clinical Profile of End Stage Renal Disease Patients Undergoing Hemodialysis in a Tertiary Care Hospital of Nepal","authors":"R. Mandal, Rajan Pande, K. Yadav, Kuldip Goit","doi":"10.3126/jaim.v12i1.56678","DOIUrl":"https://doi.org/10.3126/jaim.v12i1.56678","url":null,"abstract":"BACKGROUND Maintenance hemodialysis is a popular treatment modality of renal replacement therapy for end stage renal disease patients. The clinical profile of end-stage renal disease (ESRD) and dialysis in Mid Western Nepal are scarce. This study aimed to study the clinical profile of ESRD patients undergoing hemodialysis at the tertiary care Hospital. \u0000METHODS This study was a single center based cross sectional observational study carried out over a period from 15th December 2022 to 15th February 2023 in Department of Medicine. A total of 40 patients undergoing maintenance hemodialysis were enrolled in the study. Data about Socio demographic profiles , clinical data, duration of chronic kidney disease (CKD), major comorbidity, the presumed etiology of ESRD, duration of haemodialysis, laboratory parameters including Renal function tests etc were entered in MS Excel and analyzed through SPSS 21. \u0000RESULTS A total of 40 patients were enrolled in the study. Males were 25(62.5%) and females were 15(37.5%). The mean age of the patient was 45.75±15.2 years. The most common cause of end stage renal disease and reasons for admission were hypertension nephropathy 36(90%) and Type 2 diabetes mellitus 9(22.5%) respectively. Anemia was the most common hematological findings in ESRD patients (>90%) followed by hypocalcemia in 65%. \u0000CONCLUSIONS Hypertensive nephropathy was the commonest cause for CKD followed by diabetic nephropathy and glomerulonephritis. Early detection and effective management of these illnesses can delay the onset, progression of CKD to end stage and subsequent morbidity and the requirement of renal replacement therapy.","PeriodicalId":374721,"journal":{"name":"Journal of Advances in Internal Medicine","volume":"85 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122206741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of single coronary artery with congenital absence of right coronary artery 单冠状动脉合并先天性右冠状动脉缺失一例

Journal of Advances in Internal Medicine Pub Date : 2023-07-15 DOI: 10.3126/jaim.v12i1.56680

R. Rajbhandari, J. Shah, Arya Pradhan, Rebika Dangol, Utsav Dangol

引用次数: 0

Sudden upsurge of COVID-19 cases in China: A global threat 中国新冠肺炎病例激增:全球威胁

Journal of Advances in Internal Medicine Pub Date : 2023-07-15 DOI: 10.3126/jaim.v12i1.56681

Sai Yogesh, T. Singh, A. Kashyap, Indrajit Banerjee

引用次数: 0

A study on demographic and clinicopathological characteristics of severe acute pancreatitis in a tertiary-level intensive care unit in Nepal 尼泊尔三级重症监护病房重症急性胰腺炎的人口学和临床病理特征研究

Journal of Advances in Internal Medicine Pub Date : 2023-07-15 DOI: 10.3126/jaim.v12i1.56675

K. Khanal, S. Poudel, A. Ghimire, Ashim Regmi, Bikash Khadka, Manoj Bist, S. Shrestha, R. Sharma, U. Shrestha

{"title":"A study on demographic and clinicopathological characteristics of severe acute pancreatitis in a tertiary-level intensive care unit in Nepal","authors":"K. Khanal, S. Poudel, A. Ghimire, Ashim Regmi, Bikash Khadka, Manoj Bist, S. Shrestha, R. Sharma, U. Shrestha","doi":"10.3126/jaim.v12i1.56675","DOIUrl":"https://doi.org/10.3126/jaim.v12i1.56675","url":null,"abstract":"BACKGROUND AND AIMS Severe acute pancreatitis can have serious consequences and a high mortality rate and may necessarily require intensive care unit admission. This study is to describe the demographic and clinicopathological characteristics of severe acute pancreatitis (SAP) in a tertiary-level intensive care unit (ICU).\u0000METHODS The study was designed retrospectively with a diagnosis of severe acute pancreatitis (SAP) admitted to the tertiary-level adult ICU “between” January 2019 to December 2022.\u0000RESULTS A total of 52 patients were enrolled in this study. The maximum numbers of patients were between 41 to 52 years of age, with a median age of 47.6 years. Gallstone (biliary) was identified as the most important etiological factor associated with severe acute pancreatitis. Among the known etiological factors, 52% of the cases were related to gallstone disease, 28.8% were due to alcohol, 7 (13.4%) to other causes (such as idiopathic, post-viral, post-ERCP, and drug-induced), and 5.7% were due to triglycerides. In our study, the most common symptoms were abdominal pain and vomiting. And the majority of patients recovered with conservative treatment. The majority 48 (92.3%) of patients improved, while 4 (7.6%) died. Eighteen (34.6%) patients required Mechanical ventilation (MV), while 10 (19%) with vasopressor supports. Eleven patients (21%) had evidence of an acute kidney injury on admission. Three patients (5.7%) underwent surgery, including necrosectomy and open cholecystectomy. The median length of ICU stay was 6.3 days.\u0000CONCLUSIONS The most common cause of severe acute pancreatitis was gallstone, followed by alcohol-related. SAP was seen more commonly in the male gender in the age group of 41-52 years. The most common presenting symptoms were abdominal pain and vomiting. Most SAP cases could be managed conservatively.","PeriodicalId":374721,"journal":{"name":"Journal of Advances in Internal Medicine","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127481538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of new onset arrhythmia after non cardiac surgery 非心脏手术后新发心律失常的发生率

Journal of Advances in Internal Medicine Pub Date : 2023-07-15 DOI: 10.3126/jaim.v12i1.56676

R. Rajbhandari, J. Shah, Arya Pradhan, Rebika Dangol, Utsav Dangol, Ashreyata Manandhar, B. Banskota, Niraj Baidhya, T. Bajracharya

{"title":"Incidence of new onset arrhythmia after non cardiac surgery","authors":"R. Rajbhandari, J. Shah, Arya Pradhan, Rebika Dangol, Utsav Dangol, Ashreyata Manandhar, B. Banskota, Niraj Baidhya, T. Bajracharya","doi":"10.3126/jaim.v12i1.56676","DOIUrl":"https://doi.org/10.3126/jaim.v12i1.56676","url":null,"abstract":"BACKGROUND Although new-onset arrhythmia are a common problem in cardiothoracic surgery, their incidence in major non- cardiac surgery has not been studied properly. The aim of the study is to assess the incidence of arrhythmia after non cardiac surgery. While we have some data on postop arrhythmia after general surgery, we don’t have much data on orthopedic surgery, and good proportion of our patient in the study belong to this category. Thus it is also aimed to compare the incidence of arrhythmia in different types of surgery. \u0000METHODOLOGY The present study is a retrospective cohort of 100 patients who recently underwent surgery between 2023 January 1st till 2023 June 1st. All included patients were monitored in ICU and post-operative ward after surgery. 100 patients (28 female and 72 male) without any history of prior arrhythmia were analyzed and included in the study. Incidence of postoperative arrhythmia (PA) was observed and compared in patients undergoing different types of surgery. Impact of age factor on the incidence of PA was also studied. \u0000RESULTS Incidence of overall PA among all patients were 31%. Incidence of significant PA were 14.3%. Incidence of significant PA was highest in gastro-surgery patients (22%) whereas orthopedics patients had 11% incidence of PA. \u0000CONCLUSION Gastro surgery seems to give high impact on incidence of PA. In our analysis, age of the patient appear to be associated with the causation of PA.","PeriodicalId":374721,"journal":{"name":"Journal of Advances in Internal Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121964211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical profile of critically ill patients admitted with Dengue in a tertiary level hospital in Nepal: A retrospective study 尼泊尔一家三级医院收治的重症登革热患者的临床概况:一项回顾性研究

Journal of Advances in Internal Medicine Pub Date : 2023-02-12 DOI: 10.3126/jaim.v11i2.52394

G. S. Shrestha, A. Pradhan, Satyam Kharga, Manjit Shrestha, Tenzing Lobsel, Birendra Kumar Raut, Bal Chandra Karki, N. Poudel, R. Gautam, N. Maharjan

{"title":"Clinical profile of critically ill patients admitted with Dengue in a tertiary level hospital in Nepal: A retrospective study","authors":"G. S. Shrestha, A. Pradhan, Satyam Kharga, Manjit Shrestha, Tenzing Lobsel, Birendra Kumar Raut, Bal Chandra Karki, N. Poudel, R. Gautam, N. Maharjan","doi":"10.3126/jaim.v11i2.52394","DOIUrl":"https://doi.org/10.3126/jaim.v11i2.52394","url":null,"abstract":"BACKGROUND AND AIMS Dengue is a viral disease transmitted by mosquitoes. The burden of disease related to Dengue is considerable in tropical and sub-tropical countries. Recently, many countries observed the outbreak of Dengue. Our study aims to explore the clinical profile and outcome of the dengue positive cases admitted in the intensive care unit (ICU) of a tertiary level hospital in Lalitpur. \u0000METHODS We conducted a retrospective single center study in patients with proven Dengue, admitted to ICU. Data were collected between 20th August and 15th October 2022. Data collected were the baseline characteristics of patients, signs and symptoms and need for organ support. Patients were graded according to WHO severity scale. \u0000RESULTS A total of 31 cases were admitted during the study period. Fever, vomiting and malaise were the common presenting symptoms. Comorbidities like hypertension and diabetes were common. Hypotension, requiring inotropic support was present in nine (29.0%) of cases. Ten patients (32.3%) required respiratory support. Derange hepatic and renal function were common. Five patients (16.1%) presented with clinically significant bleeding. Six (19.4%) of the cases expired in ICU. Among the non-survivors, five (83.3%) had severe Dengue and one (16.7%) case had Dengue with warning signs. \u0000CONCLUSION Critically ill patients with Dengue have multisystem involvement. Severe Dengue and Dengue with warning signs is associated with significant morbidity and mortality.","PeriodicalId":374721,"journal":{"name":"Journal of Advances in Internal Medicine","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115316427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Echocardiographic Evaluation of Cardiopulmonary Evaluation of Cardiopulmonary Functions in Patients with Cirrhosis of Liver and Correlation with Severity of Disease 超声心动图评价肝硬化患者心肺功能及其与病情严重程度的相关性

Journal of Advances in Internal Medicine Pub Date : 2023-02-12 DOI: 10.3126/jaim.v11i2.52395

Hari Prasad Panthi, D. Koirala, R. Pathak, Brindeswari Kafle Bhandari, A. Jha, R. Hamal, Mohan Bhusal, Manoj Lamsal, Susmita Gyawali

{"title":"An Echocardiographic Evaluation of Cardiopulmonary Evaluation of Cardiopulmonary Functions in Patients with Cirrhosis of Liver and Correlation with Severity of Disease","authors":"Hari Prasad Panthi, D. Koirala, R. Pathak, Brindeswari Kafle Bhandari, A. Jha, R. Hamal, Mohan Bhusal, Manoj Lamsal, Susmita Gyawali","doi":"10.3126/jaim.v11i2.52395","DOIUrl":"https://doi.org/10.3126/jaim.v11i2.52395","url":null,"abstract":"BACKGROUND Cirrhosis is the end result of varieties of chronic liver disease. A large proportion of patients with cirrhosis develop cardiopulmonary complication. The aim of this study was to evaluate the cardiopulmonary functions of patient with cirrhosis of liver and to correlate these abnormalities with CTP and MELD score. \u0000METHODS The study involved 81 cirrhotic patients admitted in Department of Gastroenterology of TUTH over a period of one year. The diagnosis of cirrhosis was established and clinical evaluation and investigation done. \u0000RESULTS The mean age of cirrhotic patients included in the study was 52 years. Alcohol was most common cause of cirrhosis (75.31%). The mean CTP score and MELD score was 10.02±1.77 and 23.59±7.53 respectively. Thirty patients (37.03%) had prolonged QTc interval, which had statistically significant association with alcohol as etiology of cirrhosis (p = 0.04). More than half (50.62%) of patients had diastolic dysfunction but it was not statistically significantly associated with CTP and MELD-Na score. Seven patients had evidence of intrapulmonary shunting, which had statistically significant association with MELD-Na score (p =0.01). Similarly, total 5 patients (6.17%) had PPHTN but there was no statistically significant association with CTP and MELD-Na score. Seventeen patients had dilated left atrium with no statistically significant association with CTP score and MELD-Na score. \u0000CONCLUSION There was significant incidence of cardiopulmonary abnormalities in cirrhotic patients. Every patient with decompensated cirrhosis irrespective of severity of disease should be evaluated for cardiopulmonary complication with a noninvasive, real-time, rapid imaging transthoracic contrast echocardiography.","PeriodicalId":374721,"journal":{"name":"Journal of Advances in Internal Medicine","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126617344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dengue Fever Presenting as Acute Pancreatitis: A Case Series 登革热表现为急性胰腺炎:一个病例系列

Journal of Advances in Internal Medicine Pub Date : 2023-02-12 DOI: 10.3126/jaim.v11i2.52414

K. Khanal, S. Poudel, A. Ghimire, Ashim Regmi, Rashmita Bhattarai, Aakash Pandey

引用次数: 1