Journal of Otology最新文献_第9页

A comparison of the quality of life of parents of children using hearing aids and those using cochlear implants 使用助听器和人工耳蜗儿童父母的生活质量比较

Journal of Otology Pub Date : 2022-10-01 DOI: 10.1016/j.joto.2022.06.005

Saranya Arya Mundayoor, Prabuddha Bhatarai, Prashanth Prabhu

{"title":"A comparison of the quality of life of parents of children using hearing aids and those using cochlear implants","authors":"Saranya Arya Mundayoor, Prabuddha Bhatarai, Prashanth Prabhu","doi":"10.1016/j.joto.2022.06.005","DOIUrl":"10.1016/j.joto.2022.06.005","url":null,"abstract":"<div><h3>Objective</h3><p>The goal of this study was to evaluate the quality of life of parents of children who use hearing aids (HA) with those who use cochlear implants (CI) in the Indian context and document any differences found.</p></div><div><h3>Methods</h3><p>The Kannada version of the AQoL-4D was administered in a modified fashion to 131 parents (87 HA and 44 CI). Sociodemographic details were collected for supplemental information on the intervention strategy used.</p></div><div><h3>Results</h3><p>A total of 49 parents (29 HA and 20 CI) responded to the questionnaire sent. The mean total scores for both the groups were similar (HA group = 17.9 (SD = 5.5), CI group = 17.2 (SD = 3.4)), as was the score for the first subscale (HA group = 8.6 (SD = 2.9); CI group = 8.5 (SD = 2.6)) of the AQoL-4D. No significant differences were found between the two groups on either scores [Total Score: U (N<sub>HA</sub> = 29, N<sub>CI</sub> = 20) = 280.5, z = −0.194, <em>p</em> > 0.05; Subscale 1 Score: U (N<sub>HA</sub> = 29, N<sub>CI</sub> = 20) = 281.5, z = −0.176, <em>p</em> > 0.05]. The degree of hearing loss in the hearing aid group was equivalent to that of the cochlear implant group but this did not appear to influence parental quality of life.</p></div><div><h3>Conclusion</h3><p>Parents of children with hearing aids and cochlear implants appear to be similar on several psychosocial factors in the realms of functional, social, and psychological well-being. In terms of parental quality of life, hearing aids and cochlear implants appear to be equally effective intervention techniques.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 4","pages":"Pages 211-217"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ea/b8/main.PMC9547105.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33518529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cartilage tympanoplasty in the treatment of adhesive otitis media with and without Eustachian tube balloon dilatation 软骨鼓室成形术治疗伴有和不伴有耳咽管球囊扩张的粘连性中耳炎

Journal of Otology Pub Date : 2022-10-01 DOI: 10.1016/j.joto.2022.08.002

Ahmed abdel rahman abdel aziz , Ahmed Mahmoud Youssef , Mostafa Mohamed Mostafa , Mostafa talaat , Khaled Mohamed Abdelzaher , Ahmed Adel Sadeq

{"title":"Cartilage tympanoplasty in the treatment of adhesive otitis media with and without Eustachian tube balloon dilatation","authors":"Ahmed abdel rahman abdel aziz , Ahmed Mahmoud Youssef , Mostafa Mohamed Mostafa , Mostafa talaat , Khaled Mohamed Abdelzaher , Ahmed Adel Sadeq","doi":"10.1016/j.joto.2022.08.002","DOIUrl":"10.1016/j.joto.2022.08.002","url":null,"abstract":"<div><h3>Purpose</h3><p>To compare cartilage tympanoplasty (CT) combined with eustachian tube balloon dilatation (ETBD) and cartilage tympanoplasty alone as a surgical treatment modality for adhesive otitis media (AdOM) in terms of graft healing, audiological outcomes, and impact on life style, using Chronic Otitis Media Outcome Test 15 (COMOT-15).</p></div><div><h3>Methods</h3><p>50 patients with AdOM were randomly classified into 2 groups: 25 patients for cartilage tympanoplasty only (CT group) and 25 patients for cartilage tympanoplasty combined with eustachian tube balloon dilatation (CT + ETBD group). Clinical outcomes in both groups were compared at 3 and 6 months of follow up.</p></div><div><h3>Results</h3><p>There was no significant difference in graft healing between the two groups. Postoperative COMOT-15 scores significantly decreased in both groups with a significant difference between the groups with regard to the decrease in COMOT-15 scores at 3 and 6 months of follow-up (P < 0.05). Hearing improvement was achieved, as the mean preoperative ABG was 26.5 ± 5.4 and 27.1 ± 4.6 dB, and the mean postoperative ABG at 6 months was 19.4 ± 4.4 and 14.6 ± 3.9 dB in the CT and the CT + ETBD groups, respectively. The difference in the magnitude of ABG reduction in the two groups was significant at 3 and 6 months of postoperative follow-up (P < 0.05) in favour of the CT + ETBD group.</p></div><div><h3>Conclusion</h3><p>ETBD can increase the success rate of cartilage tympanoplasty in patients with AdOM by enhancing the audiological outcome and quality of life.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 4","pages":"Pages 226-231"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6a/c5/main.PMC9547107.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33518526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of diurnal changes on dichotic listening in younger adults with normal hearing 日变化对听力正常的年轻成人二元听力的影响

Journal of Otology Pub Date : 2022-10-01 DOI: 10.1016/j.joto.2022.06.003

Praveen Prakash, K.P. Vismaya, Dhruvan S. Mahesh, Prashanth Prabhu

{"title":"Effect of diurnal changes on dichotic listening in younger adults with normal hearing","authors":"Praveen Prakash, K.P. Vismaya, Dhruvan S. Mahesh, Prashanth Prabhu","doi":"10.1016/j.joto.2022.06.003","DOIUrl":"10.1016/j.joto.2022.06.003","url":null,"abstract":"<div><h3>Background</h3><p>Diurnal changes can be defined as the time of the day over an individual's performance level for different activities that involve physical and mental tasks.</p></div><div><h3>Objective</h3><p>The current study aimed to evaluate the effect of diurnal changes in scores obtained for the Dichotic Consonant-Vowel paradigm by young adults with normal hearing sensitivity.</p></div><div><h3>Method</h3><p>Based on the ‘Morningness-Eveningness questionnaire’ given by Horne & Ostberg, the subjects were divided into moderately-morning, intermediate and moderately-evening categories. The Dichotic Consonant-Vowel tests were performed during morning and evening, and the right ear, left ear and double correct scores were compared between morning and evening for each category.</p></div><div><h3>Results</h3><p>There was significant diurnal changes noted for moderately morning and evening categories, where morning-type individuals performed better during morning and evening-type individuals performed better during the evening. The scores of intermediate individuals remained unchanged between morning and evening test results.</p></div><div><h3>Conclusion</h3><p>Diurnal change is a phenomenon associated with an individual's biological clock mechanism. Hence, attention and inhibitory controls aid them in carrying out tasks that require sufficient physical and mental efforts. The current study suggests that clinicians and researchers consider diurnal changes as an extraneous variable that could affect the reliability of the Dichotic Consonant-Vowel test results.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 4","pages":"Pages 191-196"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/cc/main.PMC9547108.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33518931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in the regulation mechanism of SOX10 SOX10调控机制研究进展

Journal of Otology Pub Date : 2022-10-01 DOI: 10.1016/j.joto.2022.08.003

Jingcui Qi , Long Ma , Weiwei Guo

引用次数: 0

Profiles and predictors of onset based differences in vocal characteristics of adults with auditory neuropathy spectrum disorder (ANSD) 成人听神经病变谱系障碍(ANSD)的声带特征差异的概况和预测因素

Journal of Otology Pub Date : 2022-10-01 DOI: 10.1016/j.joto.2022.08.001

Prateek Lokwani, Prashanth Prabhu, Kavassery Venkateswaran Nisha

{"title":"Profiles and predictors of onset based differences in vocal characteristics of adults with auditory neuropathy spectrum disorder (ANSD)","authors":"Prateek Lokwani, Prashanth Prabhu, Kavassery Venkateswaran Nisha","doi":"10.1016/j.joto.2022.08.001","DOIUrl":"10.1016/j.joto.2022.08.001","url":null,"abstract":"<div><h3>Purpose</h3><p>Onset-based differences are understudied in Auditory Neuropathy Spectrum Disorder (ANSD) in dimensions such as voice, which is addressed in the study. The study aimed to profile and predict the best metrics of onset-related differences in acoustic vocal characteristics of early and late-onset ANSD patients.</p></div><div><h3>Methods</h3><p>31 participants (15 early and 16 late-onset) aged 15–30 years diagnosed with ANSD were included in the study. The sustained phonation of vowel /i/ recorded by the participants using android based smartphones of selected configuration was sent over email to the experimenter. Acoustic parameters (fundamental frequency, harmonic frequencies, jitter, shimmer, harmonic-to-noise ratio, cepstral peak prominence -CPP, and pitch sigma) were analysed using Praat software.</p></div><div><h3>Results</h3><p>Results revealed significantly increased (p < 0.05) fundamental frequency along with decreased F2 and F3 of /i/ in the early-onset ANSD compared to the late-onset group, which can be explained based on differences in the pathophysiology of the disorder. Although not statistically significant, mean perturbations (jitter and shimmer), harmonic-to-noise ratio, cepstral peak prominence, and pitch sigma were more affected in the early-onset group, reflective of lowered auditory feedback and periodicity in their voice samples. Results of discriminant analysis marked the emergence of F2, F3, and CPP as the most sensitive metrics for onset-based group differences in voice characteristics.</p></div><div><h3>Conclusions</h3><p>The findings from the study highlight the role of acoustical voice evaluation (especially CPP, F2 & F3) in verifying the onset of ANSD disorder. The insights from the onset-based differences seen in vocal characteristics can indirectly help audiologists in deciding the management options for ANSD.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 4","pages":"Pages 218-225"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/04/74/main.PMC9547112.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33518524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient decrease in sound tolerance levels following hearing deprivation in normal-hearing subjects 听力正常受试者听力剥夺后声音耐受水平的短暂性下降

Journal of Otology Pub Date : 2022-10-01 DOI: 10.1016/j.joto.2022.09.001

Eleazar Graterón , Tricia Scaglione , Shriya Airen , Stefania Goncalves , Sinay A. Ceballos , David Baguley , Juan A. Chiossone

{"title":"Transient decrease in sound tolerance levels following hearing deprivation in normal-hearing subjects","authors":"Eleazar Graterón , Tricia Scaglione , Shriya Airen , Stefania Goncalves , Sinay A. Ceballos , David Baguley , Juan A. Chiossone","doi":"10.1016/j.joto.2022.09.001","DOIUrl":"10.1016/j.joto.2022.09.001","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the circadian influence on sound sensitivity produced by temporal hearing deprivation in healthy normal human subjects.</p></div><div><h3>Design</h3><p>Participants underwent bilateral earplugging before completion of anthropometry, the author's developed questionnaire, the Hamilton Anxiety and Depression Inventory, pure tone audiometry (PTA), stapedial reflex thresholds (SRT), distortion products otoacoustic emissions input/output (DPOAE-I/O), and uncomfortable loudness levels (ULLs). Afterward, the participants were randomly divided into group A, starting at 8:00 a.m. and finishing at 8:00 p.m., and group B, starting at 4:00 p.m. and ending at 4:00 a.m. Serum cortisol levels and audiological test results were obtained at the beginning and end of the session and 24-h free urinary cortisol levels were measured.</p></div><div><h3>Study sample</h3><p>Thirty healthy volunteers.</p></div><div><h3>Results</h3><p>PTA was 2.68 and 3.33 dB HL in groups A and B, respectively, with no statistical difference between them. ULLs were significantly lower in group A compared to group B, with an average of 8.1 dB SPL in group A and 3.3 dB SPL in group B (p < 0.0001). A SRT shift was observed in group A, with no difference in group B, and a night shift in DPOAE-I/O in group B.</p></div><div><h3>Conclusions</h3><p>Reduced loudness tolerance is demonstrated during daytime hearing deprivation in contrast to nighttime; this may be due to increased central gain in the awake cortex.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 4","pages":"Pages 232-238"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/58/main.PMC9547106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33518528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Auditory symptoms and autistic spectrum disorder: A scoping review and recommendations for future research 听觉症状和自闭症谱系障碍:范围回顾和对未来研究的建议

Journal of Otology Pub Date : 2022-10-01 DOI: 10.1016/j.joto.2022.08.004

Sara Timms , Sirat Lodhi , Jack Bruce , Emma Stapleton

{"title":"Auditory symptoms and autistic spectrum disorder: A scoping review and recommendations for future research","authors":"Sara Timms , Sirat Lodhi , Jack Bruce , Emma Stapleton","doi":"10.1016/j.joto.2022.08.004","DOIUrl":"10.1016/j.joto.2022.08.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Auditory symptoms in individuals with Autistic Spectrum Disorder (ASD) are well described within the neurodevelopmental literature, yet there is minimal mention of ASD in Otolaryngology literature. This is surprising considering the potential clinical and diagnostic implications of this link, and the potential for ASD to present to Otolaryngologists in the form of unexplained auditory symptoms. The aims of this literature review were to explore the intersection of auditory symptoms and ASD from the perspective of clinical Otolaryngology, and to outline a clinically focused research agenda based on emerging themes relevant to Otolaryngology.</p></div><div><h3>Methods</h3><p>We searched Pubmed, Embase, Ovid and Cochrane library for studies until November 2021. Four authors independently reviewed 227 publications identified. 39 were filtered into the final analysis. The PRISMA 2020 guidelines were followed. The heterogeneity of literature meant that a Systematic Review was not feasible. Included studies were therefore classified thematically, forming the basis of the scoping review.</p></div><div><h3>Results</h3><p>Diagnostic theories for auditory symptoms in ASD include the entire auditory pathway and brain. There is a growing body of literature on auditory symptoms in ASD, suggesting that a primary diagnosis of ASD should be considered in patients presenting with otherwise unexplained auditory symptoms, and indicating a learning need for Otolaryngologists and audiologists, to whom these patients may present.</p></div><div><h3>Conclusion</h3><p>We recommend a research agenda focusing on multidisciplinary collaboration, stakeholder engagement, responsible clinical screening, and clarification of pathophysiological mechanisms and terminology.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 4","pages":"Pages 239-246"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33518525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Auditory cortical stimulability in non habilitated individuals – An evidence from CAEPs 非适应能力个体的听觉皮层刺激-来自caep的证据

Journal of Otology Pub Date : 2022-07-01 DOI: 10.1016/j.joto.2022.05.001

Hariprakash Palaniswami , Aju Abraham , Krishna Yerraguntla

{"title":"Auditory cortical stimulability in non habilitated individuals – An evidence from CAEPs","authors":"Hariprakash Palaniswami , Aju Abraham , Krishna Yerraguntla","doi":"10.1016/j.joto.2022.05.001","DOIUrl":"10.1016/j.joto.2022.05.001","url":null,"abstract":"<div><h3>Objective</h3><p>The effect of long term auditory deprivation on Cortical Auditory Evoked Potentials (CAEPs) especially in human models is not well explored. Hence, the current study was aimed to investigate the effects of long-term auditory deprivation and stimulability of auditory cortex in non habilitated congenitally deaf adolescents and adults using CAEPs.</p></div><div><h3>Methods and Results</h3><p>A total of 27 non-habilitated congenitally deaf adolescents/adults with age and gender matched normal hearing adolescents/adults participated in the study. The congenitally deaf group was fitted with high gain hearing aids (first fit). Further, the CAEPs were recorded. The obtained CAEP components were assessed for group effect, source and topographical differences. The between group analysis for CAEP responses showed a significant difference only for P2 latency and amplitude. The source analysis revealed that, in the normal hearing group for CAEPs, the sources were within the temporal regions. However, in the congenitally deaf group, along with the temporal cortex, the bilateral prefrontal cortex also was activated.</p></div><div><h3>Conclusion</h3><p>The findings revealed that it is possible to stimulate and evoke a matured CAEP response from a long deprived auditory system with adequate acoustic stimulation. The presence of CAEP responses is indicative of the functionality of the innate auditory pathway and the crossmodal plasticity in long auditory deprived individuals.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 3","pages":"Pages 146-155"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/bb/main.PMC9270565.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40514870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of subjective visual vertical in patients with posterior canal benign paroxysmal positional vertigo as a prognostic marker after canalith repositioning maneuver 主观上视垂直在后管良性阵发性位置性眩晕患者中作为后管复位后预后指标的作用

Journal of Otology Pub Date : 2022-07-01 DOI: 10.1016/j.joto.2022.03.002

Sanjeev Saxena , Bhaumik Patel , Ravi Roy , Himanshu Swami , Sanajit Kumar Singh , Sunil Goyal , Rajeev Chugh , Devendra Kumar Gupta , Sween Banger , Mahesh Ravanikutty , Sneha Yadav

{"title":"Role of subjective visual vertical in patients with posterior canal benign paroxysmal positional vertigo as a prognostic marker after canalith repositioning maneuver","authors":"Sanjeev Saxena , Bhaumik Patel , Ravi Roy , Himanshu Swami , Sanajit Kumar Singh , Sunil Goyal , Rajeev Chugh , Devendra Kumar Gupta , Sween Banger , Mahesh Ravanikutty , Sneha Yadav","doi":"10.1016/j.joto.2022.03.002","DOIUrl":"10.1016/j.joto.2022.03.002","url":null,"abstract":"<div><h3>Objective</h3><p>To study the potential role of subjective visual vertical (SVV) as a prognostic marker for canalith repositioning maneuver (CRM) in patients with posterior canal benign paroxysmal positional vertigo (PC-BPPV) for the Indian population.</p></div><div><h3>Methods</h3><p>SVV was examined in 30 patients with PC-BPPV before and after canalith repositioning maneuver and after complete resolution of PC-BPPV. Study parameters included the mean of 10 angular tilt readings and direction of deviation, which were compared before and after CRM and following complete resolution of PC-BPPV.</p></div><div><h3>Results</h3><p>The angle of SVV tilt was greater and deviated towards the affected ear before CRM in all patients, which decreased significantly shortly after CRM and continued to decrease after complete resolution of PC-BPPV (p < 0.0001).</p></div><div><h3>Conclusions</h3><p>SVV can be used to test utricular dysfunction in PC-BPPV. The angle of tilt improves in response to CRM, which may be used as a prognostic marker in patients with PC-BPPV receiving CRM.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 3","pages":"Pages 111-115"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ca/af/main.PMC9270559.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40515424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The association between radiological spreading pattern and clinical outcomes in necrotizing external otitis 坏死性外耳炎放射学播散模式与临床预后的关系

Journal of Otology Pub Date : 2022-07-01 DOI: 10.1016/j.joto.2022.05.002

W. Leentje van der Meer , Ahmed B. Bayoumy , Josje J. Otten , Jerome J. Waterval , Henricus P.M. Kunst , Alida A. Postma

{"title":"The association between radiological spreading pattern and clinical outcomes in necrotizing external otitis","authors":"W. Leentje van der Meer , Ahmed B. Bayoumy , Josje J. Otten , Jerome J. Waterval , Henricus P.M. Kunst , Alida A. Postma","doi":"10.1016/j.joto.2022.05.002","DOIUrl":"10.1016/j.joto.2022.05.002","url":null,"abstract":"<div><h3>Objectives</h3><p>Necrotizing external otitis (NEO) is a rare infectious disease of the skull base. The purpose of this study was to determine whether clinical outcomes of NEO can be correlated to different infectious spread patterns.</p></div><div><h3>Methods</h3><p>Retrospective chart review from 2010 to 2019 with NEO patients, who were divided into two cohorts: single spreading patterns (group A) or complex spreading patterns (group B) as diagnosed by CT. Clinical symptoms, diagnostic and treatment delay, course of disease, complications, and duration of antibiotic exposure were retrospectively collected from patient records.</p></div><div><h3>Results</h3><p>41 NEO patients were included, of which 27 patients belonged to group A (66%). The disease-related mortality rate was 12.2% among the entire cohort, no differences were found between group A and B. Higher rates of N.VII (42.9% vs 14.8% P = 0.047) and N. IX palsies were found in group B compared to group A (28.6% vs 3.7%, P = 0.039). The median duration of antibiotic use was significantly different for a complex spreading pattern, clinical recovery and hospitalizations. Complications were associated with higher diagnostic delay and with a complex spread pattern. The median duration of follow-up was 12.0 (IQR 6.0–19.5) months.</p></div><div><h3>Conclusion</h3><p>NEO is a severe disease, with significant mortality and morbidity (cranial nerve palsies). The radiological spread pattern may assist in predicting clinical outcome. Furthermore, complex spread patterns are associated with higher rates of clinical nerve palsies (N. VII and N.IX), complications, surgery rates and longer duration of antibiotic use. Diagnostic delay was associated with mortality, complications and facial palsies.</p></div><div><h3>Level of evidence</h3><p>Level IV.</p></div>","PeriodicalId":37466,"journal":{"name":"Journal of Otology","volume":"17 3","pages":"Pages 156-163"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/a5/main.PMC9270564.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40515425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0