Indian Journal of Transplantation最新文献_第2页

Management of bone and mineral disease in renal transplant patients 肾移植患者骨矿物质疾病的处理

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_35_23

Ashwini Dondapati, Priyanka Govindhan, Priya Subashchandrabose, A. Govindaraj, M. Mathew, G. Abraham

引用次数: 0

Deceased-Donor renal transplantation: A single-center experience from a tertiary care hospital in North India 已故捐赠者肾移植：北印度一家三级护理医院的单中心经验

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_53_22

S. Chadha, D. Choudhury, V. Goel, Anurag Gupta, V. Tiwari, V. Bhargava, M. Malik, Ashwani K Gupta, A. Bhalla, D. Rana

{"title":"Deceased-Donor renal transplantation: A single-center experience from a tertiary care hospital in North India","authors":"S. Chadha, D. Choudhury, V. Goel, Anurag Gupta, V. Tiwari, V. Bhargava, M. Malik, Ashwani K Gupta, A. Bhalla, D. Rana","doi":"10.4103/ijot.ijot_53_22","DOIUrl":"https://doi.org/10.4103/ijot.ijot_53_22","url":null,"abstract":"Introduction: Deceased-donor renal transplants can help cope up with the increasing demand of renal allografts in India. We evaluated the outcomes of deceased-donor renal transplantation at our center. Methods: This retrospective study analyzed the donor and recipient characteristics along with graft and patient survival in deceased-donor renal transplant recipients at our center between April 2011 and October 2021. Results: The mean age of recipients (n = 21) and deceased donors was 48 ± 9.4 and 39.3 ± 8.7 years, respectively. Male:female ratio among recipients was 1.6:1 while that in donors was 2:1. Chronic glomerulonephritis (71.4%) was the most common native kidney disease. Most patients received antithymocyte globulin (80.9%) as induction and tacrolimus-based triple-drug regimen (80.4%) as maintenance therapy. The median follow-up duration was 32.8 months. Graft dysfunction was reported in 57.1% (n = 12/21) patients; acute tubular necrosis was the most common reason (n = 5). Six patients died, and sepsis was the most common reason for death (n = 3/6; 50%); 66.7% (n = 4/6) deaths occurred within the first 6 months. The mean graft survival time was 106.2 months (95% confidence interval: 95.4–116.6). The cumulative proportion of graft survival was 95.2% (n = 20/21) at 3 and 5 years. The cumulative proportion of patient survival was 80.9% at 3 years and 76.2% at 5 years. Conclusion: Patient outcomes over 5 years follow-up were good and suggest that deceased-donor transplants should be encouraged along with living-donor transplants to cover the huge demand–supply mismatch in renal replacement therapy.","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"17 1","pages":"236 - 240"},"PeriodicalIF":0.3,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48929599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Social media coverage of the 32nd Annual conference of the Indian Society of Organ transplantation 2022: Unity in diversity 社交媒体对2022年印度器官移植学会第32届年会的报道：多样性中的团结

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_20_23

Sourabh Sharma, V. Kute, Anand Chellappan, D. Bajpai, M. Balwani, M. Sahay, N. Prasad

{"title":"Social media coverage of the 32nd Annual conference of the Indian Society of Organ transplantation 2022: Unity in diversity","authors":"Sourabh Sharma, V. Kute, Anand Chellappan, D. Bajpai, M. Balwani, M. Sahay, N. Prasad","doi":"10.4103/ijot.ijot_20_23","DOIUrl":"https://doi.org/10.4103/ijot.ijot_20_23","url":null,"abstract":"Background: The 32nd edition of the Indian Society of Organ Transplantation's yearly conference was recently hosted in Nagpur, coinciding with the 2nd Mid-term Meeting of the Liver Transplantation Society of India and the 15th Annual International Conference of Network and Alliance of Transplant Coordinators. Aims and Objectives: We are delighted to present our insights and observations on the social media coverage of #ISOT22. Materials and Methods: In order to ensure comprehensive coverage, a specialized social media team was assembled by the ISOT. This team comprised of twenty-five dedicated educators who attended the conference live. Social media coverage was done mainly by live-tweeting, taking faculty interviews, and sharing images of presentation slides. Results: Social media played a crucial role in covering the #ISOT22 event, with Twitter being the most extensively used platform. There were 2.318 million impressions with 2037 conference tweets with the hashtag #ISOT2022Nagpur. Total number of participants on Twitter was 177 and average tweets/hour were three. There were twelve average tweets per participant. Conclusions: The use of social media at 32nd Annual Conference offered several benefits, including the dissemination of presented scientific research and engagement with both physical and virtual attendees.","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"17 1","pages":"233 - 235"},"PeriodicalIF":0.3,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49657022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

An extremely rare masquerader – A case of chronic allograft dysfunction 极为罕见的假面舞者-慢性同种异体移植物功能障碍1例

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_17_23

M. Khan, V. Siddini, V. Mahesha, S. Ballal

{"title":"An extremely rare masquerader – A case of chronic allograft dysfunction","authors":"M. Khan, V. Siddini, V. Mahesha, S. Ballal","doi":"10.4103/ijot.ijot_17_23","DOIUrl":"https://doi.org/10.4103/ijot.ijot_17_23","url":null,"abstract":"47 year old lady who was detected to have hypertension at the age of 25 years, with renal dysfunction (Creatinine – 2.5 mg/dl), progressed to End stage renal disease requiring hemodialysis at the age of 31 years. She was on maintenance hemodialysis for the next 18 months and underwent a deceased donor renal transplant in 2009. Her post transplant period was uneventful and her creatinine was 1.2 until September 2021. Her creatinine showed a gradual rise to 1.9 mg/dl with increased requirement of anti hypertensives and increasing proteinuria with protein estimation showing 3950 mg/day. She underwent an allograft biopsy which showed duplication of the glomerular basement membranes and glomerulitis with c4d negative on immunofluorescence. She was treated with intravenous immunoglobulin and Rituximab for the same with not much improvement. However, an ultrasound of the transplant kidney showed bulky and echogenic transplant kidney with mild hydronephrosis and prominent renal sinus fat. MR Urogram showed extensive lymphangiectasia around the transplant kidney and ureter with markedly enlarged and edematous kidney. The collecting system and ureter are encased by the lymphangiectasia. After the treatment of CABMR her creatinine improved to 1.7 mg/dl and proteinuria reduced to 2100 mg/day. However her lymphangiectasia persisted and is being managed conservatively with no intervention planned. There are very few reported cases of Lymphangiectasia post renal transplant.","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"17 1","pages":"249 - 251"},"PeriodicalIF":0.3,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43246612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined laparoscopic appendectomy and open kidney implantation in a transplant recipient: The need, timing, and route of surgery - A case report 联合腹腔镜阑尾切除术和开放肾移植术:手术的需要，时机和途径-一个病例报告

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_134_20

Somasundaram Soundappan, Sambandam Swaminathan, Hulagi Jayanth, Kanchi Prabhu

引用次数: 0

ABO-Incompatible and human leukocyte antigen-incompatible kidney transplant in a highly sensitized patient with hepatitis-B 高度致敏的乙型肝炎患者的ABO血型不相容和人类白细胞抗原不相容肾移植

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_6_23

Suhas S. Bavikar, Vaibhav Ganjewar, A. Oswal, Purva Bavikar

引用次数: 0

Breaking the barrier: Successful kidney transplant in two patients from a SARS-CoV-2-Infected deceased donor in India: Case report and short review 突破障碍:印度一名感染sars - cov -2的已故捐赠者的两名患者成功进行肾脏移植:病例报告和简短回顾

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_95_22

Sudeep Prakash, B. Datt, B. Kumar, Abhishek Shukla

{"title":"Breaking the barrier: Successful kidney transplant in two patients from a SARS-CoV-2-Infected deceased donor in India: Case report and short review","authors":"Sudeep Prakash, B. Datt, B. Kumar, Abhishek Shukla","doi":"10.4103/ijot.ijot_95_22","DOIUrl":"https://doi.org/10.4103/ijot.ijot_95_22","url":null,"abstract":"There is the acute shortage of organs in India due to very low deceased organ donation rate. The COVID-19 pandemic had a huge impact on organ transplant programs, leading to slowing down of these programs worldwide. At present, with the SARS-CoV-2 infection becoming endemic and frequently presenting as asymptomatic or mild infection, deceased donors are likely to be incidentally positive for this infection. Most guidelines worldwide advocate rejecting the organs from such donors. Utilization of organs from these donors can improve the donor pool. Data suggest that carefully selected nonlung organs from such donors, with asymptomatic or mild SARS-CoV-2 infection, dying of other causes, are not associated with adverse outcomes. We present the cases of two end-stage kidney disease patients on hemodialysis, who were transplanted with kidneys from a deceased donor, infected with SARS-CoV-2 virus. Over 3 months of follow-up, the patients did not show any sign of COVID-19 infection or COVID-related kidney dysfunction and are now maintaining normal kidney function. This was the first incident of a successful kidney transplant from donor infected with SARS-CoV-2 virus, in India.","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"17 1","pages":"255 - 257"},"PeriodicalIF":0.3,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44617356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tobacco chewing and oral cancer in a renal transplant recipient 咀嚼烟草与肾移植患者口腔癌的关系

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_58_23

Rakesh Shinde, N. Prasad

引用次数: 1

A prospective observational study to know the origin of lymphorrhea in post-renal transplant patients using creatine phosphokinase and lactate dehydrogenase 应用肌酸激酶和乳酸脱氢酶了解肾移植后患者淋巴漏起源的前瞻性观察研究

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_41_22

Eeshansh Khare, D. Sarkar, Debojyoti Bhattacharjee, D. Pal

{"title":"A prospective observational study to know the origin of lymphorrhea in post-renal transplant patients using creatine phosphokinase and lactate dehydrogenase","authors":"Eeshansh Khare, D. Sarkar, Debojyoti Bhattacharjee, D. Pal","doi":"10.4103/ijot.ijot_41_22","DOIUrl":"https://doi.org/10.4103/ijot.ijot_41_22","url":null,"abstract":"Introduction: Renal transplantation provides the best result as a long-term renal replacement therapy. Lymphorrhea is considered a common surgical complication of renal transplantation. Although nonsurgical factors are also associated, it is primarily due to damage and improper ligation of lymphatic vessels draining donor kidney and perivascular lymphatics of iliac vessels. Lymphorrhea is associated with prolongation of hospital stay and increased chances of infection and it may lead to lymphocele formation. Hence, to localize the origin of postoperative lymphorrhea in transplant recipients in wake for its definitive management, the enzymatic activity of the two enzymes, namely, creatine phosphokinase (CPK) and Lactate dehydrogenase (LDH) in the drain fluid was evaluated. Materials and Methods: A total of 68 renal transplant recipients (including live and deceased-donor [DD] transplantation) were evaluated for2 years. The enzymatic value of CPK and LDH was calculated in perigraft drain fluid. It was compared with the values of CPK and LDH in postradical cystectomy pelvic drain fluid and simple renal cortical cyst fluid. The average value of CPK in pelvic drain fluid and LDH in renal cortical cyst fluid was considered as their baseline value in lymphatics draining lower limb and renal lymphatics, respectively. Results: The source for postoperative lymphorrhea in DD and live-related donor was iliac lymphatics, whereas in live unrelated donor, it was iliac and graft kidney lymphatics. Conclusion: Drain fluid assessment for CPK and LDH activity can localize the origin of lymphatic leak in renal transplant recipients.","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"17 1","pages":"215 - 219"},"PeriodicalIF":0.3,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48846489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A narrative review of vaccine-induced thrombotic thrombocytopenia in organ donation and transplantation: Current evidence and implications 器官捐献和移植中疫苗诱导的血栓性血小板减少症的叙述性回顾:当前的证据和意义

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Indian Journal of Transplantation Pub Date : 2023-04-01 DOI: 10.4103/ijot.ijot_12_22

V. Kute, S. Chauhan, N. Prasad, H. Meshram

{"title":"A narrative review of vaccine-induced thrombotic thrombocytopenia in organ donation and transplantation: Current evidence and implications","authors":"V. Kute, S. Chauhan, N. Prasad, H. Meshram","doi":"10.4103/ijot.ijot_12_22","DOIUrl":"https://doi.org/10.4103/ijot.ijot_12_22","url":null,"abstract":"Vaccine-induced thrombotic thrombocytopenia (VITT) has been recently linked with coronavirus disease (COVID-19) vaccines. It becomes crucial for the transplant communities to have a rigorous approach for accepting VITT donors, as the reports of such transplantation have been associated with thrombotic complications, graft loss, and deaths. The magnitude of facing a VITT donor in transplantation practices is unknown and also the management protocol. However, as per the limited data, it is better to avoid such transplants, and in the case of emergency transplants, the risk-benefit ratio should be weighed. All transplantation from VITT donors should be appropriately counseled before procurement. The organs should undergo deliberate examination for functionality by clinical, laboratory, and radiological parameters. In doubtful cases, a preimplantation biopsy is mandated to rule out any thrombosis. VITT donors are suggested to be treated with newer oral anti-coagulation and intravenous immunoglobulin. Platelet transfusion is best avoided in a VITT donor. There is no established protocol for any modification in surgical procedure, anesthesia, or immunosuppressive medicines in the recipients. The recipients should undergo extensive clinical and laboratory monitoring for any possible complications. No prophylactic therapy is recommended at present but candidates with a history of any COVID-19 vaccine within 30 days, should be avoided. In summary, the evidence for diagnosis and management of VITT donors is based only on a few reports, but with current knowledge, it is advisable to take a multidisciplinary approach to assess all benefits and risks before accepting or discarding organs.","PeriodicalId":37455,"journal":{"name":"Indian Journal of Transplantation","volume":"17 1","pages":"169 - 173"},"PeriodicalIF":0.3,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47314594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1