Transgender Health最新文献

Transgender Health in the Middle East Region: What Do We Know So Far? A Literature Review. 中东地区的跨性别健康：到目前为止我们知道什么？文献综述

IF 2 4区医学

Transgender Health Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI: 10.1089/trgh.2022.0080

Stephanie Farah, Youssef Rizk, Madona Azar

{"title":"Transgender Health in the Middle East Region: What Do We Know So Far? A Literature Review.","authors":"Stephanie Farah, Youssef Rizk, Madona Azar","doi":"10.1089/trgh.2022.0080","DOIUrl":"10.1089/trgh.2022.0080","url":null,"abstract":"Purpose: Our aim is to review transgender people in terms of education, religion, financial security, quality of life (QOL), sexual orientation, behaviors, relationships, access to health care, and gender-affirming therapies in the Middle East region.Methods: Electronic databases were used. Eligible studies were those targeting transgender people exclusively in Middle Eastern countries.Results: Lesbian, gay, bisexual, transgender, and queer people face discrimination with poor access to education and health care. More than half (56%) of trans women admitted that religion is important, and 54% identified as Muslim. The majority of trans women (81%) reported financial hardship, 75% lacked insurance coverage, and 40% claimed a monthly income of <$500. Depression and suicide attempts were common. Discrimination was also endemic in medical settings. QOL was significantly lower. They were more likely to be engaged in coercive sex and sex work and reported negative or absent family relationships. Finally, transgender people reported high concern with their body image and gender confirmation treatments.Conclusion: Publications in transgender health showed a sharp rise after 2005, however, it is still an understudied and an under-published topic, particularly in the Middle East. This review is the first to summarize the global situation of transgender people in the Middle East, and to reveal disparities in terms of education, religion, finance, mental/physical health, access to health care, QOL, sexual orientation, behaviors, relationships, and gender confirmation treatments. Larger studies are warranted to further study this population and create positive interventions that can improve their overall well-being.","PeriodicalId":37265,"journal":{"name":"Transgender Health","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41989724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transgender and Non-Binary Surgery Registry: Building a Patient-Focused Registry for Genital Gender Affirming Surgery. 跨性别和非二元手术登记处：建立一个以患者为中心的生殖器性别确认手术登记处

IF 2 4区医学

Transgender Health Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI: 10.1089/trgh.2022.0111

Geolani W Dy, Gaines Blasdel, Daniel Dugi, Christi Butler, James M Hotaling, Jeremy B Myers, Isak Goodwin, Rachel Bluebond-Langner, Lee C Zhao, Cori A Agarwal

{"title":"Transgender and Non-Binary Surgery Registry: Building a Patient-Focused Registry for Genital Gender Affirming Surgery.","authors":"Geolani W Dy, Gaines Blasdel, Daniel Dugi, Christi Butler, James M Hotaling, Jeremy B Myers, Isak Goodwin, Rachel Bluebond-Langner, Lee C Zhao, Cori A Agarwal","doi":"10.1089/trgh.2022.0111","DOIUrl":"10.1089/trgh.2022.0111","url":null,"abstract":"Purpose: High quality data regarding long-term clinical and patient-reported outcomes (PROs) of genital gender-affirming surgery (GGAS) are lacking, and transgender and non-binary (TGNB) community voices have not historically been included in research development. These factors limit the utility of current research for guiding patients, clinicians, payers, and other GGAS stakeholders in decision-making. The Transgender and Non-Binary Surgery (TRANS) Registry has been developed to meet the needs of GGAS stakeholders and address limitations of traditional GGAS research.Methods: Development of the TRANS Registry occurred over several developmental phases beginning in May 2019 to present. Stakeholder engagement was performed throughout these phases, including: determination of key clinical outcomes and PROs, creation and implementation of data collection tools within the electronic health record (EHR), and development of centralized registry infrastructure.Results: The TRANS Registry is a prospective observational registry of individuals seeking vaginoplasty and vulvoplasty. The EHR-enabled infrastructure allows patients and clinicians to contribute longitudinal outcomes data to the TRANS Registry. We describe our community engaged approach to designing the TRANS Registry, including lessons learned, challenges, and future directions.Conclusions: The TRANS Registry is the first multicenter initiative to prospectively track the health of individuals seeking vaginoplasty and vulvoplasty using EHR-enabled methods, engaging TGNB community members and clinicians as partners in the process. This process may be used as a model for registry development in other emerging fields where high-quality longitudinal outcomes data are needed.","PeriodicalId":37265,"journal":{"name":"Transgender Health","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49047369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FACE-Q Satisfaction Ratings Are Higher After Facial Feminization Surgery Than Hormone Replacement Therapy Alone. 面部女性化手术后的FACE-Q满意度比单独的激素替代疗法高

IF 2 4区医学

Transgender Health Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI: 10.1089/trgh.2022.0209

Mariana N Almeida, Aaron S Long, Adam H Junn, Jean Carlo Rivera, Sacha C Hauc, David P Alper, Joshua Z Glahn, Mica C G Williams, John A Persing, Michael Alperovich

{"title":"FACE-Q Satisfaction Ratings Are Higher After Facial Feminization Surgery Than Hormone Replacement Therapy Alone.","authors":"Mariana N Almeida, Aaron S Long, Adam H Junn, Jean Carlo Rivera, Sacha C Hauc, David P Alper, Joshua Z Glahn, Mica C G Williams, John A Persing, Michael Alperovich","doi":"10.1089/trgh.2022.0209","DOIUrl":"10.1089/trgh.2022.0209","url":null,"abstract":"Purpose: Facial feminization surgery (FFS) is associated with improved psychological outcomes in transgender patients. We aimed to evaluate the impact of FFS on patient satisfaction with facial appearance using validated, patient-reported outcome tools.Methods: Patients were recruited to complete a FACE-Q survey at least 6 months after their FFS. FACE-Q modules used included \"Satisfaction with Facial Appearance Overall,\" \"Facial Attributes\" (forehead/eyebrows, nose, cheeks, cheekbone, chin, jawline, and neck), \"Decision,\" \"Outcomes,\" \"Psychological Function,\" and \"Social Function.\" \"Satisfaction with Facial Appearance Overall\" was compared to FACE-Q outcomes in transgender patients on hormone replacement therapy (HRT), alone.Results: Twenty-three patients completed the survey. Rhinoplasty was the most common procedure (82.6%). Insurance was rated as a major barrier in 50% of patients. \"Satisfaction with Facial Appearance Overall\" using the FACE-Q was 69.3, with \"Psychological Function\" rated at 73.7 and \"Social Function\" rated at 76.1. FFS was associated with a higher overall satisfaction in facial appearance compared to patients on HRT for 3 months (69.3 vs. 48.5, p<0.01) and 12 months, alone (69.3 vs. 54.4, p<0.001). Wait time for FFS of less than a year (β=-20.4, p=0.04) and undergoing FFS at a younger age (β=-1.4, p<0.001) were independently associated with higher satisfaction scores in overall facial appearance.Conclusions: FFS is associated with greater satisfaction with overall facial appearance, especially compared to transgender patients only on HRT. Insurance was the greatest barrier to receiving FFS. Improved access to surgery is needed to yield higher overall satisfaction with facial appearance.","PeriodicalId":37265,"journal":{"name":"Transgender Health","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47467860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Community Advisory Boards as a Form of Community-Engaged Research for Gender Diverse Youth. 社区咨询委员会作为面向性别多样化青年的社区参与研究的一种形式

IF 2 4区医学

Transgender Health Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI: 10.1089/trgh.2022.0194

Stanley Ray Vance, Luz Venegas, Jae Sevelius

引用次数: 0

Perceived Stress Predicts Drug Use in Transgender Women: The Mediating Role of Loneliness. 感知压力预测跨性别女性的药物使用：孤独感的中介作用

IF 2 4区医学

Transgender Health Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI: 10.1089/trgh.2022.0121

Lulu Xu, Ruijie Chang, Yingjie Chen, Danni Xia, Chen Xu, Xiaoyue Yu, Hui Chen, Rongxi Wang, Yujie Liu, Shangbin Liu, Xin Ge, Tiecheng Ma, Ying Wang, Yong Cai

{"title":"Perceived Stress Predicts Drug Use in Transgender Women: The Mediating Role of Loneliness.","authors":"Lulu Xu, Ruijie Chang, Yingjie Chen, Danni Xia, Chen Xu, Xiaoyue Yu, Hui Chen, Rongxi Wang, Yujie Liu, Shangbin Liu, Xin Ge, Tiecheng Ma, Ying Wang, Yong Cai","doi":"10.1089/trgh.2022.0121","DOIUrl":"10.1089/trgh.2022.0121","url":null,"abstract":"Purpose: Drug use is quite common in transgender women, but the mechanisms of the drug use remain unclear. The purpose of this study was to investigate the mediating role of loneliness in perceived stress and the drug use among transgender women.Methods: A cross-sectional survey was conducted from April to September 2018 in Shenyang and Kunming, China, among 247 transgender women. Chinese Perceived Stress Scale, the Chinese version of 8-item UCLA Loneliness Scale, a drug use questionnaire, and a demographic characteristic questionnaire were included in the survey. Descriptive analysis, logistic regression, and mediation analysis were done using SPSS Statistics version 26.0 and Mplus version 8.3.Results: The mean age of transgender women in the study was 33.04 years (standard deviation=8.14). Around 33.20% (n=82) of transgender women reported ever using one kind of drugs, the most commonly used drugs were rush (79.20%), ice (8.50%), and 5-MeO-DIPT (8.50%). Univariate logistic regression showed that perceived stress (odds ratio [OR]=1.73, 95% bootstrap confidence intervals [CI]=1.27-2.36) and loneliness (OR=1.62, 95% CI=1.23-2.13) had a significant association with drug use, all p [ps] <0.01. The effect of perceived stress on drug use was partially mediated by feeling of loneliness (estimate=0.09, standard error=0.04, p<0.05), the mediating effect (0.09) accounted for 27.27% of the total effect (0.33).Conclusion: Perceived stress can positively predict drug use. Loneliness plays an important role in drug use among transgender women.","PeriodicalId":37265,"journal":{"name":"Transgender Health","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46099134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Staged Phalloplasty by Metoidioplasty First Does Not Appear to Lower Complication Rates. 分阶段阴茎成形术先行输卵管成形术并不能降低并发症发生率

IF 2 4区医学

Transgender Health Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI: 10.1089/trgh.2022.0186

Mieke Waterschoot, Piet Hoebeke, Wesley Verla, Anne-Françoise Spinoit, Stan Monstrey, Marlon Buncamper, Nicolaas Lumen

{"title":"Staged Phalloplasty by Metoidioplasty First Does Not Appear to Lower Complication Rates.","authors":"Mieke Waterschoot, Piet Hoebeke, Wesley Verla, Anne-Françoise Spinoit, Stan Monstrey, Marlon Buncamper, Nicolaas Lumen","doi":"10.1089/trgh.2022.0186","DOIUrl":"10.1089/trgh.2022.0186","url":null,"abstract":"Purpose: Genital gender-affirming surgery in transmasculine patients encompasses both metoidioplasty and phalloplasty. Some patients opt to undergo staged phalloplasty by metoidioplasty first (SPMF). The aim of this study was to evaluate whether SPMF is associated with less surgical complications compared with immediate phalloplasty (IP).Methods: Our institutional database was retrospectively evaluated to identify transmasculine patients who underwent SPMF between 2006 and 2020. These patients were matched based on the type of flap (radial forearm free flap vs. anterolateral thigh flap) and for the time period in regard to patients who underwent IP. Both groups were compared on patient characteristics, perioperative and postoperative outcomes.Results: Twenty-seven patients with SPMF were matched with 27 IP patients. Median follow-up after phalloplasty was held, respectively, 32 and 33 months after the intervention for SPMF and IP (p=0.99). There were no significant differences in age, body mass index, and smoking habits between both groups. For SPMF, metoidioplasty required subsequent corrective surgery before phalloplasty in three patients (11%). For SPMF and IP, median operation time was 396 and 410 min (p=0.6), median hospital stay was 16 and 17 days (p=0.5), and median catheter stay was 19 and 20 days (p=0.9). In both groups, 16 patients (59%) needed at least one additional surgical procedure for postoperative complications, urethral complications (stricture, fistula), and/or flap-related complications.Conclusion: In our cohort, complications were not reduced by SPMF. In case metoidioplasty is considered as a step toward phalloplasty, separate morbidity of metoidioplasty must be taken into account.","PeriodicalId":37265,"journal":{"name":"Transgender Health","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43148125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recorded Diagnosis of Gender Identity Disorder Is Strongly Associated with Suicide Mortality. 性别认同障碍的记录诊断与自杀死亡率密切相关

IF 2 4区医学

Transgender Health Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI: 10.1089/trgh.2022.0110

Geoffrey D Kahn, Elizabeth Lockhart, Gregory E Simon, Ashli A Owen-Smith, Rebecca C Rossom, Arne L Beck, Frances L Lynch, Yihe G Daida, Christine Y Lu, Stephen Waring, Hsueh-Han Yeh, Brian K Ahmedani

引用次数: 0

Transgender Women with HIV Demonstrate Unique Non-Alcoholic Fatty Liver Disease Profiles. 感染艾滋病毒的跨性别女性表现出独特的非酒精性脂肪肝特征

IF 2 4区医学

Transgender Health Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI: 10.1089/trgh.2022.0182

Jordan E Lake, Ana N Hyatt, Han Feng, Hongyu Miao, Anoma Somasunderam, Netanya S Utay, Kathleen E Corey

{"title":"Transgender Women with HIV Demonstrate Unique Non-Alcoholic Fatty Liver Disease Profiles.","authors":"Jordan E Lake, Ana N Hyatt, Han Feng, Hongyu Miao, Anoma Somasunderam, Netanya S Utay, Kathleen E Corey","doi":"10.1089/trgh.2022.0182","DOIUrl":"10.1089/trgh.2022.0182","url":null,"abstract":"Purpose: Non-alcoholic fatty liver disease (NAFLD) prevalence and severity may be higher in people with human immunodeficiency virus (HIV) than the general population, and vary with sex and age. We explored NAFLD characteristics by gender.Methods: Adult transgender women (TW), cisgender women (CW), and cisgender men (CM) with HIV on antiretroviral therapy and without other known causes of liver disease underwent screening for NAFLD (2017-2020). Circulating factors associated with NAFLD were measured. Hepatic steatosis and fibrosis were assessed using transient elastography by controlled attenuation parameter (CAP) and liver stiffness measurement (LSM), respectively. Analysis of variance/Wilcoxon testing compared normally/non-normally distributed variables, respectively. Logistic regression evaluated factors associated with CAP and LSM.Results: Participants (n=194) had median age 48 years and body mass index 28.3 kg/m2; 42% were CM, 37% TW, and 21% CW; 95% were non-white; and 16% had diabetes, 40% dyslipidemia, and 49% hypertension. NAFLD prevalence was 59% using CAP ≥248 dB/m (≥S1 steatosis), 48% using CAP ≥260 dB/m (≥S2 steatosis), and 32% using CAP ≥285 dB/m (≥S3 steatosis). Compared to CM and CW, TW had the highest median CAP scores, were more likely to have ≥S2 steatosis, and had the highest insulin resistance, interleukin-6, and fetuin-A values. TW off versus on gender-affirming hormone therapy (GAHT) had slightly higher median CAP scores.Conclusion: TW on GAHT had less hepatic steatosis than TW not on GAHT, although overall NAFLD severity was greater than expected for TW compared to CM and CW. The effects of estrogen supplementation and androgen deprivation on liver health in TW require further study.","PeriodicalId":37265,"journal":{"name":"Transgender Health","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41279292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gender Minority Stress, Resilience, and Psychological Distress: The Role of Resilience Among Transgender and Gender Diverse Youth. 性别少数派压力、弹性与心理困扰:跨性别与多元性别青年弹性的作用

IF 2 4区医学

Transgender Health Pub Date : 2024-08-16 eCollection Date: 2024-08-01 DOI: 10.1089/trgh.2022.0117

Michael Miller-Perusse, Keith J Horvath, Erin Kahle, Rob Stephenson

{"title":"Gender Minority Stress, Resilience, and Psychological Distress: The Role of Resilience Among Transgender and Gender Diverse Youth.","authors":"Michael Miller-Perusse, Keith J Horvath, Erin Kahle, Rob Stephenson","doi":"10.1089/trgh.2022.0117","DOIUrl":"10.1089/trgh.2022.0117","url":null,"abstract":"Purpose: Gender minority (GM) stress, resulting from distal (i.e., external) and proximal (i.e., internal) stigma-based stressors, is thought to drive mental health disparities among transgender and gender diverse (TGD) youth. We tested the gender minority stress and resilience (GMSR) model hypotheses that distal GM stress effects on mental health are partially mediated by proximal GM stress and moderated by GM-specific resilience (i.e., community connectedness, identity pride) among a U.S. national sample of TGD youth.Methods: As part of an HIV prevention study (NCT03185975), 159 TGD youth (ages 15-24) completed an online survey that included the GMSR measure, assessing distal and proximal GM stress and GM resilience, and the 18-item Brief Symptom Inventory, assessing past-7-day psychological distress. Three models linking GMSR constructs to psychological distress were tested using PROCESS v4.0: (1) simple partial mediation, (2) moderated partial mediation, and (3) serial partial mediation.Results: A direct effect of distal GM stress was observed in all models. An indirect effect through proximal GM stress alone was observed in model 1, but not models 2 or 3. In model 2, resilience did not moderate the effects of distal or proximal GM stress. In model 3, indirect effects were observed through proximal GM stress and GM resilience serially as well as GM resilience alone.Conclusion: Larger prospective studies are needed to confirm the role of GM resilience as a mediator, rather than moderator, of GM stress effects on mental health and a critical, rather than supplementary, target for mental health intervention among TGD youth.","PeriodicalId":37265,"journal":{"name":"Transgender Health","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11456763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41736935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Retrospective Study of the Use of Gonadotropin-Releasing Hormone Analogs and Testosterone in Transgender Boys: Who, What, When, and for How Long? 在变性男孩中使用促性腺激素释放激素类似物和睾酮的回顾性研究:谁，什么，何时，持续多久?

IF 2 4区医学

Transgender Health Pub Date : 2024-08-16 eCollection Date: 2024-08-01 DOI: 10.1089/trgh.2022.0156

Emily J Kain, John S Fuqua, Erica A Eugster

引用次数: 0