Environments - MDPIPub Date : 2026-06-01Epub Date: 2026-06-07DOI: 10.3390/environments13060319
Adeola Shogbaike, Emmanuel Obeng-Gyasi
{"title":"Combined Effects of PFAS and Metals on Cognitive Function.","authors":"Adeola Shogbaike, Emmanuel Obeng-Gyasi","doi":"10.3390/environments13060319","DOIUrl":"10.3390/environments13060319","url":null,"abstract":"<p><strong>Background: </strong>Heavy metals and per- and polyfluoroalkyl substances (PFAS) are widespread environmental pollutants that have been linked to worsening cognition, but how the two classes act together to shape cognitive function is still not well characterized. Drawing on data from the National Health and Nutrition Examination Survey (NHANES), this observational analysis evaluated how PFAS and metals are jointly related to performance across distinct cognitive domains in older adults.</p><p><strong>Methods: </strong>We analyzed 1447 adults aged 60 years and older from the 2011-2012 NHANES cycle in a cross-sectional design study. Metal levels in serum and whole blood were determined with standardized laboratory assays. Associations of single exposures and of the overall mixture with the CERAD word-learning and recall tasks, Animal Fluency, and the Digit Symbol Substitution Test were assessed using multivariable linear regression, together with Bayesian Kernel Machine Regression (BKMR).</p><p><strong>Results: </strong>Single-exposure models produced largely modest and inconsistent associations across the cognitive measures. Within the mixture models, PFAS, especially PFOA, PFDE, and PFOS, were repeatedly flagged as influential across several domains, whereas the metals tended to matter for specific outcomes only. The strongest negative signals at elevated joint exposure emerged for memory-related measures, notably CERAD Trials 1 and 2.</p><p><strong>Conclusions: </strong>Joint exposure to PFAS and heavy metals appears to influence cognitive domains unevenly, with memory-related measures seeming more responsive as combined exposure rises. These results reinforce the value of mixture-oriented analytic strategies when investigating environmental contaminants in relation to cognitive aging.</p>","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"13 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13441233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148680351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predicting Minute Ventilation from Heart Rate in Adolescents: A Tool for Environmental Health Studies.","authors":"Celia Cacho, Meghana Giri, Kyung Hwa Jung, Ruskin Del Mundo, Aimee Layton, Stephanie Lovinsky-Desir","doi":"10.3390/environments12120448","DOIUrl":"10.3390/environments12120448","url":null,"abstract":"<p><p>Minute ventilation (VE) is central to understanding the interplay between air pollution and exercise. However, real-time measurement of VE in environmental health research is often limited by access to equipment and technical expertise. We aimed to (1) develop predictive equations for VE based on heart rate (HR) in adolescents using metabolic exercise testing data, (2) evaluate which demographic factors influenced model accuracy, and (3) compare our equations to previously published equations applied to our sample. We analyzed cardiopulmonary exercise test (CPET) data from 41 patients. VE was log-transformed, and generalized estimating equations (GEE) were used to model associations between HR and VE, adjusting for age, sex, race, ethnicity, and BMI. In the fully adjusted model, HR was a strong predictor of VE (<i>p</i>-value < 0.001); only sex was a significant covariate (<i>p</i> = 0.003). Stratification revealed a higher predicted VE at a given HR for males compared to females (y<sub>male</sub> = 0.020x + 0.813 vs. y<sub>female</sub> = 0.019x + 0.708, where y = lnVE and x = HR) with a pseudo-R<sup>2</sup> of 0.80 for males and pseudo-R<sup>2</sup> of 0.82 for females. Our predictive equations had the lowest average percent difference between measured and predicted VE, whereas prior models under- or overestimated VE in our sample. Overall, sex-specific GEEs provide a practical method to estimate VE from HR in adolescents and can serve as tools to support exposure assessment and future applications in environmental health research.</p>","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"12 12","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13341173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148406369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carla Nóbrega, Helena Ávila, Renato Coelho, Margarida Tomé, Augusta Costa
{"title":"Preferential Allocation of Currently Assimilated Carbon Induced by the Source Leaf Position on Young Cork Oaks (Quercus suber L.) in Late Spring","authors":"Carla Nóbrega, Helena Ávila, Renato Coelho, Margarida Tomé, Augusta Costa","doi":"10.3390/environments12120451","DOIUrl":"https://doi.org/10.3390/environments12120451","url":null,"abstract":"The whole-plant preferential allocation patterns of recently assimilated carbon by the source leaves of six-year-old cork oaks (Quercus suber L.) were assessed 7 days after a 14CO2 pulse-labelling in late spring (end of May). The 14CO2 assimilation was separately induced on attached leaves on branches located at the top-down 30% of the crown height, in the middle 40% and at the bottom-up 30% of the crown height of twelve plants. Our results showed that the top source leaves retained the highest amount (64%) of their own current produced carbohydrates compared to either lower (49%) or middle (42%) source leaves. The top source leaves preferentially export current carbohydrates to their most proximal sinks, namely, other leaves or their branches. However, lower source leaves exported the highest amount of current carbon, about 37%, preferentially to the root system. Roots displayed the greatest sink strength for the available current carbohydrates, due to their largest biomass (between 69% and 75% of the whole plant biomass), when other strong sinks, such as the annual leaves, were fully expanded. Taken together, our data revealed that carbon supply by leaves and delivery to roots are critical for maintaining root growth in cork oak under Mediterranean seasonal drought conditions.","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"12 12","pages":"451-451"},"PeriodicalIF":0.0,"publicationDate":"2025-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147878617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What Drives Sustainable Energy Use? A Case Study from Jordanian Households","authors":"Mohammad Jaber, Dhia Qasim, Abrar Ghaith","doi":"10.3390/environments12120452","DOIUrl":"https://doi.org/10.3390/environments12120452","url":null,"abstract":"This study examines the factors influencing energy-saving behaviors in Jordanian households by expanding the Theory of Planned Behavior (TPB). Incorporating additional variables, such as energy poverty, eco-literacy, and environmental concern, this study utilizes survey data collected through online tools. The findings reveal that environmental concern and eco-literacy significantly influence attitudes, perceived behavioral control, and subjective norms, with attitudes emerging as the dominant predictor of environmentally sustainable intentions. These intentions, in turn, positively influence actual sustainable behaviors. Energy poverty directly affects both intentions and behaviors, moderating key relationships within the model, notably diminishing the influence of attitudes on intentions and the translation of intentions into behavior. The results validate the applicability of TPB to sustainable energy practices and demonstrate the importance of addressing economic barriers. Overall, the findings suggest that fostering environmental concern and eco-literacy is necessary but insufficient without interventions that mitigate financial constraints associated with energy poverty.","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"12 12","pages":"452-452"},"PeriodicalIF":0.0,"publicationDate":"2025-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.mdpi.com/2076-3298/12/12/452/pdf?version=1763972326","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147877485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selective Adsorption Performance of a High-Capacity Mesoporous Silica Aerogel for Fluoroquinolones","authors":"Yifan Zhao, Lin Gu, Zhihan Liu, Junyu Zhang, Wei Xia, Peng Wang, Wenlei Zhai, Guangxin Yang, Xiaosheng Shen, Cheng‐Qi Fan, Cong Kong","doi":"10.3390/environments12090300","DOIUrl":"https://doi.org/10.3390/environments12090300","url":null,"abstract":"Fluoroquinolone antibiotics (FQs) are widely applied in veterinary practice and animal husbandry and frequently persist in organic waste liquids (OWLs), creating substantial environmental and health risks when untreated. A high-capacity mesoporous silica aerogel (SA-60) was produced via a cost-effective sol–gel route from water glass, followed by ambient pressure drying at 60 °C for 6 h. SA-60 exhibited pronounced selectivity, providing a maximum adsorption capacity of 630.18 mg·g−1 for enrofloxacin (ENR) in acetonitrile. Adsorption efficiency was weakly dependent on pH. Mechanistic analysis indicated combined physical and chemical interactions, with intra-particle diffusion governing the overall rate. Thermodynamic evaluation showed a spontaneous and endothermic process for ENR adsorption. Organic solvent type and water content were major determinants of adsorption efficiency. Durable performance was observed, with capacity retention above 80% after five adsorption-desorption cycles. The mesoporous architecture (surface area 249.21 m2·g−1; average pore diameter 10.81 nm) supported the high uptake. These results identify SA-60 as a sustainable adsorbent for removing hazardous FQs from OWLs, offering a simple, energy-efficient approach for the source-level control of antibiotic pollution and improved environmental management.","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"12 9","pages":"300-300"},"PeriodicalIF":0.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.mdpi.com/2076-3298/12/9/300/pdf?version=1756392570","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147332411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Environments - MDPIPub Date : 2025-08-01Epub Date: 2025-07-31DOI: 10.3390/environments12080267
John H Zimmerman, Brian Schumacher, Christopher C Lutes, Brian Cosky, Heidi Hayes
{"title":"Long-Term Performance of Passive Volatile Organic Compounds (VOCs) Samplers for Indoor Air.","authors":"John H Zimmerman, Brian Schumacher, Christopher C Lutes, Brian Cosky, Heidi Hayes","doi":"10.3390/environments12080267","DOIUrl":"10.3390/environments12080267","url":null,"abstract":"<p><p>The reliability of passive samplers in measuring volatile organic compounds (VOCs) in indoor air depends on whether the uptake rate is constant given the environmental conditions and sampler exposure duration. The first phase of this study evaluated the performance of charcoal-based, solvent-extracted passive samplers (e.g., Radiello<sup>®</sup> 130 passive samplers with white diffusive bodies) over exposure periods ranging from 1 week to 1 year in a test house with known vapor intrusion (VI). Chloroform %Bias values exceeded the ±30% acceptance criterion after 4 weeks exposure. Benzene, hexane, and trichloroethylene (TCE) concentrations were within the acceptance criterion for up to three months. Toluene and tetrachloroethylene (PCE), the two least volatile compounds, demonstrated uniform uptake rates over one year. In the second phase of this study, testing of the longer exposure times of 6 months and 1 year were evaluated with three additional passive samplers: Waterloo Membrane Sampler<sup>™</sup> (WMS<sup>™</sup>), SKC 575 with secondary diffusive cover, and Radiello<sup>®</sup> 130 passive samplers with yellow diffusive bodies. The SKC 575 and Radiello<sup>®</sup> 130 passive samplers produced acceptable results (%Bias ≤ 30%) over the 6-month exposure period, while the WMS<sup>™</sup> sampler results favored petroleum hydrocarbon more than chlorinated solvent uptake. After the 1-year exposure period, the passive sampler performances were acceptable under specific conditions of this study. The results suggest that all three samplers can produce acceptable results over exposure time periods beyond 30 days and up to a year for some compounds.</p>","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"12 8","pages":"267"},"PeriodicalIF":3.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12425130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toxic Legacy—Environmental Impacts of Historic Metal Mining and Metallurgy in the Harz Region (Germany) at Local, Regional and Supra-Regional Levels","authors":"Louisa Friederike Steingräber, Friedhart Knolle, Horst Kierdorf, Catharina Ludolphy, Uwe Kierdorf","doi":"10.3390/environments12070215","DOIUrl":"https://doi.org/10.3390/environments12070215","url":null,"abstract":"As a legacy of historical metal mining and the processing and smelting of metalliferous ores, metal pollution is a serious environmental problem in many areas around the globe. This review summarizes the history, technical development and environmental hazards of historic metal mining and metallurgical activities in the Harz Region (Germany), one of the oldest and most productive mining landscapes in Central Europe. The release of large amounts of metal-containing waste into rivers during historic ore processing and the ongoing leaching of metals from slag heaps, tailings dumps and contaminated soils and sediments are the main sources of metal pollution in the Harz Mountains and its foreland. This pollution extends along river systems with tributaries from the Harz Mountains and can even be detected in mudflats of the North Sea. In addition to fluvial discharges, atmospheric pollution by smelter smoke has led to long-term damage to soils and vegetation in the Harz Region. Currently, the ecological hazards caused by the legacy pollution from historical metal mining and metallurgy in the Harz Region are only partially known, particularly regarding the effects of changes in river ecosystems as a consequence of climate change. This review discusses the complexity and dynamics of human–environment interactions in the Harz Mountains and its surroundings, with a focus on lead (Pb) pollution. The paper also identifies future research directions with respect to metal contamination.","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"12 7","pages":"215-215"},"PeriodicalIF":0.0,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.mdpi.com/2076-3298/12/7/215/pdf?version=1750930500","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147904720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of PFAS and Metals with Cardiovascular Disease Risk: Exploring the Mediating Effect of Diet.","authors":"Augustina Odediran, Kenneth Bollen, Emmanuel Obeng-Gyasi","doi":"10.3390/environments12060178","DOIUrl":"https://doi.org/10.3390/environments12060178","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular disease (CVD) is a major global health burden influenced by genetic, behavioral, and environmental factors. Among these, exposure to per- and poly-fluoroalkyl substances (PFASs) and toxic metals has been increasingly implicated in adverse cardiovascular outcomes. However, the mediating role of dietary inflammation in these associations remains unclear.</p><p><strong>Objective: </strong>This study investigates the relationship between PFAS and metal exposures and CVD risk, focusing on the potential mediating role of diet, operationalized through the Dietary Inflammatory Index (DII). Additionally, this study examines age as an effect modifier in these associations.</p><p><strong>Methods: </strong>Utilizing data from the National Health and Nutrition Examination Survey (NHANES) 2017-2018 cycle (<i>n</i> = 660), we assessed environmental exposures (lead, cadmium, mercury, perfluorooctanoic acid-PFOA, perfluorooctane sulfonate-PFOS), dietary inflammatory potential (DII), and cardiovascular markers (blood pressure, lipid profile, C-reactive protein). Statistical analyses included linear regression and Bayesian Kernel Machine Regression-Causal Mediation Analysis (BKMR-CMA) to estimate the direct, indirect (through DII), and total effects of exposure on CVD risk biomarkers.</p><p><strong>Results: </strong>Linear regression revealed significant associations between mercury and reduced systolic blood pressure (SBP) (<i>p</i> = 0.017) and cadmium with increased C-reactive protein (CRP) (<i>p</i> = 0.006). Mediation analysis suggested dietary inflammation may play a role, though estimates were imprecise.</p><p><strong>Conclusions: </strong>PFAS and metals may influence CVD risk through inflammatory pathways, with potential age-related differences. Future longitudinal studies are needed to clarify these complex interactions, reduce measurement error, and guide age-specific exposure regulations.</p>","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"12 6","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dengyu Jiang, Tao Li, Xuanhe Liang, Xin Zhao, Shanlong Li, Yutong Li, Kokyo Oh, Haifeng Liu, Tiehua Cao
{"title":"Evaluation of Petroleum Hydrocarbon-Contaminated Soil Remediation Technologies and Their Effects on Soybean Growth","authors":"Dengyu Jiang, Tao Li, Xuanhe Liang, Xin Zhao, Shanlong Li, Yutong Li, Kokyo Oh, Haifeng Liu, Tiehua Cao","doi":"10.3390/environments12010006","DOIUrl":"https://doi.org/10.3390/environments12010006","url":null,"abstract":"The application of persulfate (PS) for the remediation of petroleum hydrocarbon contamination is among the most widely employed in situ chemical oxidation (ISCO) techniques, and it has received widespread attention due to its limited impact on soil integrity. This study employed a FeSO4-activated PS oxidation method to investigate the feasibility of remediating soil contaminated with total petroleum hydrocarbons (TPHs). The factors tested included the TPH concentration, different PS:FeSO4 ratios, the reaction time for remediation, soil physical and chemical property changes before and after remediation, and the effect of soil before and after remediation on soybean growth. The TPH degradation rate in soil was highest for high-, medium-, and low-TPHs soils—81.5%, 81.4%, and 72.9%, respectively, with minimal disruption to the soil’s physicochemical properties—when PS:FeSO4 = 1:1. The remediation verification results indicated that the condition of the soybeans was optimal when PS:FeSO4 = 1:1. Under this condition, the net photosynthetic rate, stomatal conductance, intercellular CO2 concentration, and transpiration rate all remained high. Therefore, the best remediation effect was achieved with PS:FeSO4 = 1:1, which also minimized the damage to the soil and the effects on crop growth.","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"12 1","pages":"6-6"},"PeriodicalIF":0.0,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.mdpi.com/2076-3298/12/1/6/pdf?version=1735384754","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147896267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conceptual Design of an Urban Pocket Park Located in the Site of the Occurrence of a Nineteenth-Century Chapel Using Representatives of Local Xerothermic Vegetation","authors":"Weronika Kopeć, Ewa Hanus-Fajerska, Leszek Bylina","doi":"10.3390/environments11110252","DOIUrl":"https://doi.org/10.3390/environments11110252","url":null,"abstract":"The 19th century neo-Gothic chapel located in the Stradom district of Czestochowa, Southern Poland and built at the intersection of the main streets is a recognizable landmark of great historical value. Unfortunately, the current condition of the surroundings depreciates the charm of such a chapel, and thus does not encourage people to admire it. Therefore, in order to expose such a valuable object, we planned to create a conceptual design of a pocket park around this cultural monument. When choosing the location of any park, it is recommended to know the needs of the local residents, so we conducted a survey regarding their wishes. When designing the area, we intended to use species representing the vegetation characteristic of the Krakow–Czestochowa Upland located in Southern Poland. At the same time, we used a material typical of the area, namely limestone. Design principles around the chapel were taken into account, separating the sacred and profane zones with the intention of giving this site a unique character and creating the first urban pocket park of this kind.","PeriodicalId":36821,"journal":{"name":"Environments - MDPI","volume":"11 11","pages":"252-252"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.mdpi.com/2076-3298/11/11/252/pdf?version=1731493071","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147900896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}