2009 IEEE International Ultrasonics Symposium最新文献

Conference info 会议信息

2009 IEEE International Ultrasonics Symposium Pub Date : 2019-08-01 DOI: 10.1109/icma.2016.7558986

M. Pappalardo

引用次数: 0

The growth of osteoblasts stimulated by various time duration of low intensity pulsed ultrasounds 不同时间的低强度脉冲超声刺激成骨细胞的生长

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5441471

S. Chen, Chun-Yi Chiu, Shyh-Hau Wang

{"title":"The growth of osteoblasts stimulated by various time duration of low intensity pulsed ultrasounds","authors":"S. Chen, Chun-Yi Chiu, Shyh-Hau Wang","doi":"10.1109/ULTSYM.2009.5441471","DOIUrl":"https://doi.org/10.1109/ULTSYM.2009.5441471","url":null,"abstract":"In this study, osteoblasts (OBs) were insonated with low intensity pulsed ultrasound (LIPUS) of different exposure durations to extensively investigate ultrasound exposure on the growth of cells. OBs were seeded and then were incubated for 24 hours to allow cells to be adhered on the culture plate. Subsequently, LIPUS of a fixed 100 mW/cm2 intensity from a 1 MHz and 20% duty cycle within 1 kHz pulse repetition frequency was arranged to respectively stimulate various groups of passage OBs for 3, 5, 10 and 20 minutes daily. Another experiment was also arranged using the same protocol to insonify groups of differentiation OBs for 14 days. The insonification responses for those OBs were evaluated by cell morphology, viability, alkaline phosphatase (ALP) activity, Alizarin red-S staining, and mRNA expression by reverse transcriptase ploymerase chain reaction (RT-PCR). Results showed that the proliferation of those insonified OBs for 10 minutes tended to increase to around 1.07 fold compared to cells of the control group after the fourth day of experiments. Similar tendency for the ALP activity was observed, in which the largest activity and proliferation rate of OBs were measured to be at the sixth day after insonation. The largest mineralization of OBs enhanced by LIPUS insonification also corresponded to cells insonified for 10 minutes daily. Moreover, the RT-PCR analysis revealed that those cells insonified for 10 minutes daily tended to increase 2 fold mRNA levels of osteocalcin than those of control group. This study also demonstrated that both proliferation and activation of ALP synthesis of OBs may be enhanced by LIPUS stimulation and is exposure duration dependence in which sufficient longer insonification duration brings more effective in promoting the OBs growth.","PeriodicalId":368182,"journal":{"name":"2009 IEEE International Ultrasonics Symposium","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127668730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Algorithm for estimating the attenuation slope from backscattered ultrasonic signals 后向散射超声信号衰减斜率估计算法

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5442006

A. Haak, Zachary T. Hafez, Janelle J. Anderson, M. Herd, K. Nam, E. Madsen, T. Bigelow, T. Hall, W. O’Brien

{"title":"Algorithm for estimating the attenuation slope from backscattered ultrasonic signals","authors":"A. Haak, Zachary T. Hafez, Janelle J. Anderson, M. Herd, K. Nam, E. Madsen, T. Bigelow, T. Hall, W. O’Brien","doi":"10.1109/ULTSYM.2009.5442006","DOIUrl":"https://doi.org/10.1109/ULTSYM.2009.5442006","url":null,"abstract":"In vivo attenuation slope measurements usually utilize the backscattered signal from pulse/echo ultrasound. In this work the down shift of the center frequency of an emitted ultrasound pulse with penetration depth is utilized to estimate the attenuation slope. A diffraction correction of the focused ultrasound source is performed by measuring the reflection from a planar surface positioned throughout the depth of focus. A focused single element transducer with a measured center frequency of 8.2 MHz and a fractional band width of 72% was used to interrogate four tissue mimicking phantoms. The scatterers in the tissue mimicking phantoms were glass spheres embedded in a gelatin/milk matrix. In one set of the phantoms, the backscattering strength was varied; in the other set of phantoms the attenuation slope was varied. The attenuation slope (ASBS) was estimated using pulse/echo data obtained by scanning the phantoms. The “true” attenuation slope (ASThru) was obtained from two independent insertion loss measurements performed at two different laboratories. The relative error of ASBS was investigated for different regions of interest (ROI) for all phantoms. Three different axial and lateral ROI sizes were tested. It was observed that the average relative error (average over all four phantoms) changed by less than three percent when the lateral size of the ROI was decreased by seventy percent. The axial size of the ROI was changed by thirty percent whereas the average error changed by less then three percent.","PeriodicalId":368182,"journal":{"name":"2009 IEEE International Ultrasonics Symposium","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130592710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Ultrasound-based imaging of nanoparticles: From molecular and cellular imaging to therapy guidance 纳米粒子的超声成像:从分子和细胞成像到治疗指导

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5441484

S. Mallidi, B. Wang, M. Mehrmohammadi, M. Qu, Y.-S. Chen, P. Joshi, S. Kim, K. Homan, A. Karpiouk, R. Smalling, K. Sokolov, S. Emelianov

{"title":"Ultrasound-based imaging of nanoparticles: From molecular and cellular imaging to therapy guidance","authors":"S. Mallidi, B. Wang, M. Mehrmohammadi, M. Qu, Y.-S. Chen, P. Joshi, S. Kim, K. Homan, A. Karpiouk, R. Smalling, K. Sokolov, S. Emelianov","doi":"10.1109/ULTSYM.2009.5441484","DOIUrl":"https://doi.org/10.1109/ULTSYM.2009.5441484","url":null,"abstract":"The effectiveness of an imaging technique is often based on the ability to image quantitatively both morphological and physiological functions of the tissue. Here we present several ultrasound-based imaging techniques capable of visualizing both structural and functional properties of living tissue. Each imaging system utilizes custom-made, targeted nanoparticles developed to probe specific molecular events. Therefore, images of these nanoparticles display molecular processes in the body. Furthermore, the developed nanoparticle contrast agents can also be used for image-guided molecular therapy. For each imaging system, the basic physics and principles behind each approach are described. Experimental aspects of each imaging system including fabrication of integrated imaging probes and associated imaging hardware, and design of targeted contrast agents are discussed. Finally, biomedical and clinical applications of the developed imaging approaches ranging from microscopic to macroscopic imaging of cardiovascular diseases, cancer detection, diagnosis, therapy and therapy monitoring are demonstrated and discussed.","PeriodicalId":368182,"journal":{"name":"2009 IEEE International Ultrasonics Symposium","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132955621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Evaluation of the binding force between a biotinylated microbubble and a streptavidin-coated surface by ultrasound radiation 用超声辐射评价生物素化微泡与链霉亲和素包覆表面之间的结合力

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5441969

T. Sugiura, K. Kooiman, M. Emmer, H. Vos, A. van Wamel, N. de Jong

引用次数: 1

Optical quantification of acoustic radiation force impulse-induced dynamics in a translucent phantom 半透明体中声辐射力脉冲诱导动力学的光学量化

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5441961

R. Bouchard, M. Palmeri, J. Streeter, P. Dayton

引用次数: 0

Using GPUs for beamforming acceleration on SAFT imaging 利用gpu对SAFT成像进行波束形成加速

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5441790

D. Romero, Ó. Martínez-Graullera, C. J. Martin, R. Higuti, A. Octavio

引用次数: 28

In vivo hemostasis detection at human femoral arteriotomy by ARFI ultrasound ARFI超声在人股动脉切开术中的体内止血检测

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5441426

R. Behler, M. R. Scola, T. Nichols, M. Caughey, Hongtu Zhu, C. Gallippi

引用次数: 0

Visualization of flexural wave propagation in helical coiled ultrasonic waveguide 螺旋螺旋超声波导中弯曲波传播的可视化

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5441715

R. Tanaka, M. Tanabe, K. Okubo, N. Tagawa

引用次数: 2

Operation of a high frequency piezoelectric ultrasound array with an application specific integrated circuit 用专用集成电路实现高频压电超声阵列的操作

2009 IEEE International Ultrasonics Symposium Pub Date : 2009-12-01 DOI: 10.1109/ULTSYM.2009.5441707

A. Bernassau, T. Button, Kyusun Choi, S. Cochran, C. Démoré, L. Garcia-Gancedo, D. Hutson, T. Jackson, Hyunsoo Kim, Insoo Kim, C. Meggs, S. Trolier-McKinstry, R. Tutwiler

{"title":"Operation of a high frequency piezoelectric ultrasound array with an application specific integrated circuit","authors":"A. Bernassau, T. Button, Kyusun Choi, S. Cochran, C. Démoré, L. Garcia-Gancedo, D. Hutson, T. Jackson, Hyunsoo Kim, Insoo Kim, C. Meggs, S. Trolier-McKinstry, R. Tutwiler","doi":"10.1109/ULTSYM.2009.5441707","DOIUrl":"https://doi.org/10.1109/ULTSYM.2009.5441707","url":null,"abstract":"Integration of a piezoelectric high frequency ultrasound (HFUS) array with a microfabricated application specific integrated circuit (ASIC) performing a range of functions has several advantages for ultrasound imaging. The number of signal cables between the array/electronics and the data acquisition / imaging system can be reduced, cutting costs and increasing functionality. Electrical impedance matching is also simplified and the same approach can reduce overall system dimensions for applications such as endoscopic ultrasound. The work reported in this paper demonstrates early ASIC operation with a piezocomposite HFUS array operating at approximately 30 MHz. The array was tested in three different modes. Clear signals were seen in catch-mode, with an external transducer as a source of ultrasound, and in pitch-mode with the external transducer as a receiver. Pitch-catch mode was also tested successfully, using sequential excitation on three array elements, and viable signals were detected. However, these were relatively small and affected by interference from mixed-signal sources in the ASIC. Nevertheless, the functionality and compatibility of the two main components of an integrated HFUS - ASIC device have been demonstrated and the means of further optimization are evident.","PeriodicalId":368182,"journal":{"name":"2009 IEEE International Ultrasonics Symposium","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128374465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7