Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR)最新文献

Determination of Quercetin in Extracts and Herbal Products of Phyllanthus niruri by TLC Densitometry Method 薄层色谱密度法测定余甘子提取物及中草药制品中槲皮素的含量

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.1855

B. Ihsan, Ade Putri Delina, A. F. Shalas

引用次数: 0

Implementation of Ruqyah as an Alternative to Islamic Medicine in Indonesia Ruqyah在印度尼西亚作为伊斯兰医学的替代方案的实施

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.2126

Kartika Ratnasari, Cindy Natasya, Yasmin Erly Agustin, Rahmad Suprastiyo, Zulfa Erfania Azzuhri, M. Amiruddin

引用次数: 0

Terapi Bekam (Hijamah) dalam Perspektif Islam dan Medis 从伊斯兰和医学的角度来看，刺痛疗法

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.2129

Hakmi Hidayat, Muhammad Amiruddin, Ana Fadilia Aktifa, Mahardika Chory Haryadi, N. Azzahra

{"title":"Terapi Bekam (Hijamah) dalam Perspektif Islam dan Medis","authors":"Hakmi Hidayat, Muhammad Amiruddin, Ana Fadilia Aktifa, Mahardika Chory Haryadi, N. Azzahra","doi":"10.18860/planar.v2i0.2129","DOIUrl":"https://doi.org/10.18860/planar.v2i0.2129","url":null,"abstract":"Muslims have the holy book Al-Quran and Hadith as the main source of law in various issues, including health. One of the medical therapies mentioned in the Al-Qur'an and Hadith is cupping, which removes dirty blood from the body through a wound process carried out on the surface of the skin. This study aims to discover the history of cupping until it becomes a form of health therapy as well as views from the Islamic and medical side of cupping therapy. The method used is a literature study. Cupping therapy has existed since ancient Egypt and developed in various civilizations in various countries in the world, from Egypt, China, Europe, and America. The law of cupping in Islam is permissible and has been found in the books of nine hadith figures, special discussion of cupping is mentioned 275 times. The Prophet SAW recommended cupping in the middle of the month or after the middle of the month, but it is customary to do it in the third week. Cupping therapy in the medical world is explained using the approach of traditional medicine and modern medicine. Both agree that cupping therapy at certain points in the body can cure several diseases where the cupping is done or far from the area where the cupping is done. The benefits of cupping from a medical point of view are curing local ailments (neck pain, back pain, shoulder pain, knee pain, headaches, and migraines) and systematic diseases (Diabetes mellitus, hypertension, rheumatoid arthritis). In cupping therapy, it is mandatory to carry out infection control (washing hands before starting therapy, wearing complete PPE, disinfecting the skin and the place of therapy, managing waste, and trying to use disposable therapy equipment).","PeriodicalId":365916,"journal":{"name":"Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR)","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123551450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Schleichera oleosa L. on HbA1c Levels in Alloxan-Induced Rats 四氧嘧啶诱导大鼠HbA1c水平的影响

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.1825

A. Awaluddin, Andi Zulkifli AS, A. Burhan, Nurhikma Awaluddin, Hamka Amir

{"title":"The Effect of Schleichera oleosa L. on HbA1c Levels in Alloxan-Induced Rats","authors":"A. Awaluddin, Andi Zulkifli AS, A. Burhan, Nurhikma Awaluddin, Hamka Amir","doi":"10.18860/planar.v2i0.1825","DOIUrl":"https://doi.org/10.18860/planar.v2i0.1825","url":null,"abstract":"Diabetes mellitus is a chronic disease that occurs due to the failure of the pancreas to produce sufficient insulin, or the body cannot use the insulin it makes effectively. The HbA1c (glycated hemoglobin) levels show an alteration in blood glucose levels in people with diabetes. As a traditional medicine, the kesambi plant (Schleichera oleosa L.) can improve diabetic people's health due to its secondary compounds, such as alkaloids, flavonoids, tannins, steroids, and phenolic compounds, besides several empirically proven as antiulcer, anticancer, and antimicrobial effects. The study aimed to determine the effect of the ethanol extract of Kesambi leaves on HbA1c levels in alloxan-induced rats. This research used a posttest-only design method, using 18 rats divided into six groups of mice and induced by alloxan 150 mg/kg in intraperitoneal with the division of groups: group I without treatment; group II alloxan + Na CMC; group III alloxan + glibenclamide; groups IV, V, and VI, given alloxan + kesambi leaf extract 200, 400, and 600 mg/kg BW, respectively. All treatments were given orally for 23 days. HbA1c values were measured on day 24 using the Afinion HbA1c. The data obtained were analyzed using the method of comparing the measurement results of each group against the control group. The results showed that the 200, 400, and 600 mg extracts affected HbA1c levels with successive values of 5.47%, 5.37%, and 5.47% compared to the control group, namely 5.10%. This study concluded that giving kesambi leaf ethanol extract can affect HbA1c levels.","PeriodicalId":365916,"journal":{"name":"Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR)","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133833550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Benefits of Removing Dirty Blood with Traditional Cupping Treatment 传统拔火罐去污血的好处

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.2127

M. Amiruddin, Layla Intan Syafitri, Afif Rabbani, Aisya Kayla Muthmainnah, Ainun Tusamma Salsabila

{"title":"The Benefits of Removing Dirty Blood with Traditional Cupping Treatment","authors":"M. Amiruddin, Layla Intan Syafitri, Afif Rabbani, Aisya Kayla Muthmainnah, Ainun Tusamma Salsabila","doi":"10.18860/planar.v2i0.2127","DOIUrl":"https://doi.org/10.18860/planar.v2i0.2127","url":null,"abstract":"In daily life, Muslims are ordered to behave by the teachings in the Al-Quran and the sunnah of the Prophet Muhammad, including regarding health. In the world of health, it is known that alternative medicine in the style of Rasulullah SAW is known as At-Thibb Al-Nabawi; one example is cupping therapy. The purpose of preparing this paper is to master the meaning of cupping, the procedures for carrying out cupping, and knowing the urgency and virtues of cupping. The research method used is a literature study. Cupping is the oldest traditional medicine method in the world, believed to have existed since 3000 BC. It aims to remove blood contaminated with toxins resulting from metabolism through the skin's surface by using a tube or glass placed on the skin's surface as a place to collect the dirty blood. There are five types of cupping: dry cupping, wet cupping, sliding cupping, fire cupping, and synergy cupping. Cupping features include pain relief, increasing blood circulation, lowering blood pressure, overcoming cardiovascular disease, lowering cholesterol, treating diabetes mellitus, and many more.","PeriodicalId":365916,"journal":{"name":"Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129498366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Kandungan Buah Delima (Punica granatum L.) dalam Perspektif Al-Qur'an, Sunnah, dan Sains

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.2128

Sugeng Ali Mansur, Ahmad Fauzan Deroyeen, Muhfida Nur Indriyanti, Alif Kammaliyyah Annisak, Devina Rizka Fajriati, Muhammad Amiruddin

引用次数: 0

Acetylation of Emodin and Cytotoxic Activity Effect Against HepG2 Cell Lines 大黄素乙酰化及其对HepG2细胞株的细胞毒作用

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.1858

Firdayani Firdayani, Nuralih Nuralih, Siska Andrina Kusumastuti, H. Hasan

{"title":"Acetylation of Emodin and Cytotoxic Activity Effect Against HepG2 Cell Lines","authors":"Firdayani Firdayani, Nuralih Nuralih, Siska Andrina Kusumastuti, H. Hasan","doi":"10.18860/planar.v2i0.1858","DOIUrl":"https://doi.org/10.18860/planar.v2i0.1858","url":null,"abstract":"Emodin (1,3,8-trihydroxy-6-methyl-9,10-anthraquinone) is an anthraquinone bioactive compound used as a lead compound because it exhibits potential anticancer properties. Structural modifications were made at the C3 position and its relationship to cytotoxic activity against the HepG2 cell line to determine the pharmacophore group of this compound. The hydroxy group at C3 emodin is converted to an ester group to produce 3-acetyl emodin. In addition, docking simulations into the cancer target protein casein kinase-2 were also carried out to predict molecular interactions. Emodin was reacted with anhydrous acetate and confirmed the product confirmation using LCMS/MS, FTIR, 1H-NMR, and 13C-NMR. Emodin and 3-acetyl emodin were tested for cytotoxicity against HepG2 cells in vitro. Cytotoxic emodin and 3-acetyl emodin tests on HepG2 cells resulted in Cytotoxic concentrations 50 (CC50) of 0.54 mM and 0.42 mM, respectively. The results showed that modifying the C3 hydroxyl group with acetyl can increase the cytotoxic effect more than emodin. This research is expected to provide information regarding the structure-activity relationship of emodin in cancer cells and the expansion of new drug applications for additional cancers.","PeriodicalId":365916,"journal":{"name":"Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR)","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123120174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antineuroinflammatory Properties of Compounds from Ethyl Acetate Fraction of Marsilea crenata C. Presl. Against Toll-Like Receptor 2 (3A7B) In Silico 马齿苋乙酸乙酯部位化合物抗神经炎特性研究。抗toll样受体2 (3A7B)的研究

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.1831

Burhan Ma’arif, Reyhan Rahma Samudra, F. A. Muslikh, Tanaya Jati Dhrama Dewi, Luthfi Ahmad Muchlasi

{"title":"Antineuroinflammatory Properties of Compounds from Ethyl Acetate Fraction of Marsilea crenata C. Presl. Against Toll-Like Receptor 2 (3A7B) In Silico","authors":"Burhan Ma’arif, Reyhan Rahma Samudra, F. A. Muslikh, Tanaya Jati Dhrama Dewi, Luthfi Ahmad Muchlasi","doi":"10.18860/planar.v2i0.1831","DOIUrl":"https://doi.org/10.18860/planar.v2i0.1831","url":null,"abstract":"Parkinson's disease (PD) can be triggered by overactive TLR2 due to α-synuclein abnormalities and aggregation. Marsilea crenata C. Presl. leaves inhibit neuroinflammatory progression. This study aimed to predict the antineuroinflammatory activity of M. crenata leaves with TLR2 (ID 3A7B) in an in silico study. The list of chemicals was collected through metabolite profiling with UPLC-QToF MS/MS, then analyzed for physicochemical properties using SwissADME and toxicity using the ProTox II online program. This analysis confirmed the molecule's safety for therapeutic use. ChemDraw 12.0 was used to build metabolite-profiled compounds. Avogadro 1.2.0 was utilized to optimize geometry, while PyRx 0.8 was used for Autodock Vina molecular docking. Agonist-TLR2 interactions were examined using docking results from Biovia Discovery Studio 2021. Tethering is valid; the program can be used because the RMSD is less than 2. The results showed that 6 of the 84 metabolite-profiled compounds were antagonistic to 3A7B and shared similar pharmacophore distances and amino acid linkages with N-acetyl-D-glucosamine, a native ligand of 3A7B. By binding to TLR2, the compounds from the ethyl acetate fraction of M. crenata leaves may potentially inhibit PD progression.","PeriodicalId":365916,"journal":{"name":"Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR)","volume":"189 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133937715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Analysis of Antidiabetic Potential of Palmitic Acid Compounds Through In Silico Activation 通过硅活化分析棕榈酸类化合物的抗糖尿病潜能

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.1849

Ardellya Elfidaa Salsabila, Nurlaili Susanti, Z. S. Ulhaq

{"title":"Analysis of Antidiabetic Potential of Palmitic Acid Compounds Through In Silico Activation","authors":"Ardellya Elfidaa Salsabila, Nurlaili Susanti, Z. S. Ulhaq","doi":"10.18860/planar.v2i0.1849","DOIUrl":"https://doi.org/10.18860/planar.v2i0.1849","url":null,"abstract":"Diabetes Mellitus is a condition where the body's sugar level exceeds the blood's normal limit. Type 2 Diabetes Mellitus is the most common type of diabetes and is a chronic disease caused by insulin resistance and beta-cell dysfunction, resulting in decreased insulin sensitivity. The management of diabetes Mellitus is in the form of oral hypoglycemic drugs. Still, these drugs have side effects such as gastrointestinal disturbances, nausea, vomiting, hypoglycemia, macrovascular disorders, microvascular disorders, etc. So, it is necessary to seek alternative drugs to increase insulin sensitivity to lower blood sugar levels which are safer using herbal plants. One of the suspected plants that can be an alternative medicine to reduce excess blood sugar levels is the dandang gendis plant (Clinacanthus nutans). The dandang gendis plant (Clinacanthus nutans) contains palmitic acid, which can reduce excess blood sugar levels in the blood. This study aims to determine the potential of palmitic acid compounds from the Dandang gendis plant as an in silico AMPK protein activator. Methods: Qualitative descriptive method using molecular docking in silico method to determine the affinity and interaction with palmitic acid compounds in the dandang gendis plant in activating AMPK protein. Docking between palmitic acid and AMPK produces an energy value (∆Gbind) of -5.3 kcal/mol. docking of metformin resulted in the lowest energy value (∆Gbind) of 5.1 kcal/mol. The bond produced by palmitic acid docking has a fairly strong affinity for the AMPK protein of -5.3 kcal/mol. So palmitic acid, an ingredient in the dandang gendis plant (Clinacanthus nutans) has the potential as an antidiabetic.","PeriodicalId":365916,"journal":{"name":"Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124893308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scoping Review: Analysis of Alcohol Levels in Food and Beverages Using Gas Chromatography 范围综述:气相色谱法分析食品和饮料中的酒精含量

Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR) Pub Date : 2022-12-05 DOI: 10.18860/planar.v2i0.1843

S. Suryanto, F. A. Muslikh, N. Purwitasari, Burhan Ma’arif

{"title":"Scoping Review: Analysis of Alcohol Levels in Food and Beverages Using Gas Chromatography","authors":"S. Suryanto, F. A. Muslikh, N. Purwitasari, Burhan Ma’arif","doi":"10.18860/planar.v2i0.1843","DOIUrl":"https://doi.org/10.18860/planar.v2i0.1843","url":null,"abstract":"Islamic teachings explain that food or beverage should not be consumed with more than 0.5% alcohol because it is categorized as khamr, which is unlawful. In determining the levels of foods or beverages that contain alcohol, one of which is the gas chromatography method with several aspects of the method validation used. So that it can be seen how halal food or beverage is. The purpose of this scoping review is to map the available evidence related to the optimum conditions of analysis of alcohol content in a food product by gas chromatography and obtain a method of analyzing alcohol content in food products with several parameters validation methods, including selectivity, linearity, the limit of detection, precision, and accuracy. This scoping review has followed the framework of Arksey and O'Malley, which consists of identifying the problem formulation from the literature review; seeking relevant evidence; completing studies of relevant scientific articles; mapping data; conclude and reporting results. PRISMA flowchart diagram is used for the flow of evidence search. The results of this review show that there are 6 research articles obtained from the database. This review shows that the analysis of alcohol content using the gas chromatography method has high sensitivity, accuracy, validity, and recovery. It is hoped that this scoping review can be used as a reference and theoretical basis in analyzing food products using the gas chromatography method with several aspects of validity.","PeriodicalId":365916,"journal":{"name":"Proceedings of International Pharmacy Ulul Albab Conference and Seminar (PLANAR)","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134312334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0