NSMRJ: Nusantara Scientific Medical Research Journal最新文献

Leukocyte Differentiation Mice (Mus Musculus) Infected with Plasmodium Berghei after Therapy With Sargassum Duplicatum Extract 马尾藻提取物治疗感染伯氏疟原虫的白细胞分化小鼠(小家鼠

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2023-04-29 DOI: 10.58549/nsmrj.v2i01.29

A. M. Ukratalo, Suyono Lateke

{"title":"Leukocyte Differentiation Mice (Mus Musculus) Infected with Plasmodium Berghei after Therapy With Sargassum Duplicatum Extract","authors":"A. M. Ukratalo, Suyono Lateke","doi":"10.58549/nsmrj.v2i01.29","DOIUrl":"https://doi.org/10.58549/nsmrj.v2i01.29","url":null,"abstract":"Leukocytes are white blood cells produced by hematopoietic tissue that serves to help the body fight various infectious diseases as part of the immune system. Sargassum duplicatum contains steroid, alkaloid, phenol, flavonoid, saponin, and tannin compounds that can be immunomodulatory. The purpose of this research is to know the effect of methane extract of brown algae Sargassum duplicatum on the differentiation of leukocyte mice (Mus musculus) infected with Plasmodium berghei. Mice weighing 20-30 grams in Plasmodium berghei infection as much as 0.1 ml per head and left to the percentage of parasitemia reaches 1-5%. Then the mice (Mus musculus) were given brown algae methanol extract (Sargassum duplicatum) at doses 10, 100, and 200 mg / g BW for 4 consecutive days. From day 0 to 6 also made a blood smear to calculate the number of leukocytes. Data analysis will be done using ANOVA. The results showed that the administration of brown algae extracts of Sargassum duplicatum influenced in increasing the number of neutrophils, monocytes, and basophils and decreased the number of eosinophils and lymphocytes of mice infected with Plasmodium berghei to near normal range. Dose 200 mg/kg BB methanol extract of brown alga Sargassum duplicatum is a dose that can affect the number of neutrophils, eosinophils, lymphocytes, and monocytes of mice infected with Plasmodium berghei most closely to normal range.","PeriodicalId":365569,"journal":{"name":"NSMRJ: Nusantara Scientific Medical Research Journal","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116597027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant Effectiveness Test on The Formulation of Combination Facial Soap Ingredients of Ethanol Extract Lemon Peel Citrus limon and Forest Honey Apis dorsata 柠檬皮、柠檬、森林蜂蜜乙醇提取物联合香皂配方的抗氧化效果试验

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2023-04-28 DOI: 10.58549/nsmrj.v2i01.69

Sriyanty Sadsyam, Nasrawati Basir, Arafah Nurfadillah, Nurhikma Awaluddin, Selviana

{"title":"Antioxidant Effectiveness Test on The Formulation of Combination Facial Soap Ingredients of Ethanol Extract Lemon Peel Citrus limon and Forest Honey Apis dorsata","authors":"Sriyanty Sadsyam, Nasrawati Basir, Arafah Nurfadillah, Nurhikma Awaluddin, Selviana","doi":"10.58549/nsmrj.v2i01.69","DOIUrl":"https://doi.org/10.58549/nsmrj.v2i01.69","url":null,"abstract":"Citrus limon and Apis dorsata are claimed to have several active compounds namely: alkaloids, flavonoids, tannins and saponins. These compounds are known to have antioxidant activity in preventing skin damage due to free radicals and preventing premature aging. In this study, Citrus limon and Apis dorsata were formulated into facial soap ingredients. The purpose of this study was to find out whether the ethanol extract formulation in the lemon peel and the Apis dorsata forest honey has the effectiveness of antioxidants in preventing the free radicals. This research was an experimental study with physical and chemical evaluation of ingredients. The DPPH test was used to determine the antioxidant activity of the ingredients. This research used three types of formulation of Ethanol Ethanol Extract Formulation were lemon and honey forest, they were : FI (5%: 2%); FII (5%: 3%) and FIII (5%: 4%). The results of the DPPH test respectively were FI 6,16; FII 5,53 and FIII 4.39. The ingredients of Facial Soap Combination of Ethanol Extract Lemon Feel and Apis dorsata had the best antioxidant and antioxidant energy in Formula III with concentration of 5%: 4%","PeriodicalId":365569,"journal":{"name":"NSMRJ: Nusantara Scientific Medical Research Journal","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125099419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation and Effectiveness Testing of Mosquito Repellent Spray Combination of Citrusev Oil (Cymbopogon nardus) and Patchouli Oil (Pogostemon cablin) 柑桔油与广藿香油联合驱蚊喷雾的配方及效果试验

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2023-04-28 DOI: 10.58549/nsmrj.v2i01.65

Widya Ariati

{"title":"Formulation and Effectiveness Testing of Mosquito Repellent Spray Combination of Citrusev Oil (Cymbopogon nardus) and Patchouli Oil (Pogostemon cablin)","authors":"Widya Ariati","doi":"10.58549/nsmrj.v2i01.65","DOIUrl":"https://doi.org/10.58549/nsmrj.v2i01.65","url":null,"abstract":"Dengue fever is a health problem caused by the dengue virus dengue virus whose problem has not been resolved. Various attempts have been made to prevent dengue fever, one of which is chemical-based insecticides, but the use of chemicals can cause side effects ranging from mild to severe. The purpose of this study was to increase the use of natural ingredients as an alternative to mosquito repellents to minimize side effects and determine the effectiveness of the spray repelency against Aedes aegypti mosquitoes. This research method used an experimental approach using 20 mosquitoes, which were divided into five groups, namely formulation I (10% lemonggrass oil and 2% pathouli oil), formulation II (10% lemonggrass oil and 4% pathouli oil), formulation III (10% lemonggrass oil and 6% pathouli oil), control (-) ( propylene glycol and ethanol 96%) and control (+) (soffel spray) were each given the same treatment. The mist was sprayed on the arm, put in the test cage, and counted the number of mosquitoes perched on the arm for 5 minutes. The percentage of mosquito repellent power in fomulation I am 69%, formulation II is 76%, formulation III is 92%. The data were analyzed by using one-way ANOVA using the LSD (least significant difference) test; there were substantial differences between the treatment group and the level of effevtiveness of the repulsion againts the Aedes aegypti mosquito.","PeriodicalId":365569,"journal":{"name":"NSMRJ: Nusantara Scientific Medical Research Journal","volume":"337 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114370791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Hypertension Exercise on Blood Pressure Reduction in The Elderly at Wisma Seruni UPT PSTW Jember 高血压运动对老年人血压降低的影响[j]

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2023-04-28 DOI: 10.58549/nsmrj.v2i01.33

Riski Hidayaturrohkim, Echi Agnes Claudia, Yuzqi Rizqullah, Dimas Anggi Septiyansah, Nanda Leoni Agustin, Fahruddin Kurdi, Septin Wahyu Ersanti

{"title":"The Effect of Hypertension Exercise on Blood Pressure Reduction in The Elderly at Wisma Seruni UPT PSTW Jember","authors":"Riski Hidayaturrohkim, Echi Agnes Claudia, Yuzqi Rizqullah, Dimas Anggi Septiyansah, Nanda Leoni Agustin, Fahruddin Kurdi, Septin Wahyu Ersanti","doi":"10.58549/nsmrj.v2i01.33","DOIUrl":"https://doi.org/10.58549/nsmrj.v2i01.33","url":null,"abstract":"As the elderly population increases and the aging process they experience, triggers the occurrence of various diseases, especially hypertension. Improper management of hypertension causes a decrease in quality of life and morbidity in the elderly. This study aims to determine the effect of hypertension exercise on the blood pressure of the elderly at Wisma Seruni UPT PSTW Jember. The design of this study used a quasi-experimental with pretest and posttest one group design. The sampling technique used was a total of 8 respondents who met the inclusion criteria. Changes in blood pressure were measured using an aneroid sphygmomanometer and data analysis using the statistical test T-Test Dependent. The results showed that the average systolic blood pressure (SBP) before the first day of therapy was 147.5 mmHg and the second day 138.75 mmHg while the average systolic blood pressure after the elderly hypertension exercise was carried out on the first day of 140 mmHg and the second day 131.25 mmHg, the average diastolic blood pressure (DBP) before the first and second day of therapy was 84.38 mmHg while after the first day of therapy it was 82.5 mmHg and the second day was 80.63 mmHg. Based on the results of the analysis test using the dependent t-test, the SBP results before and after the intervention were 0.000 (p<0.005). There was an effect on the decrease in systolic blood pressure on the first and second day of intervention. Hypertension exercise therapy is an alternative solution to reduce blood pressure in the elderly with hypertension.","PeriodicalId":365569,"journal":{"name":"NSMRJ: Nusantara Scientific Medical Research Journal","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131678851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Angular Cheilitis in Elderly Patients 老年患者角性舌炎的处理

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2023-04-28 DOI: 10.58549/nsmrj.v2i01.35

Erine Tita Febrine, Yassir Ahmad Azzaim

引用次数: 0

Antioxidant Activity Test of Caulerpa racemosa Extract from Takalar District Using the FRAP (Ferric Reducing Antioxidant Power) Method 用FRAP法测定塔克拉拉尔地区总状茎叶提取物的抗氧化活性

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2023-04-28 DOI: 10.58549/nsmrj.v2i01.67

Andi Ulfiana Utarı, N. A., Eka Astuti

引用次数: 0

Evaluation of the Antihyperuricemia Activity of Bajakah Tampala Stem Ethanol Extract (Spatholobus littoralis Hassk.) in Male White Mice (Mus musculus) 柽柳茎乙醇提取物对雄性小白鼠抗高尿酸血症作用的评价

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2022-12-19 DOI: 10.58549/nsmrj.v1i1.28

N. Hidayah, G. I. Dalimunthe

引用次数: 0

Effectiveness of Resam Fern Leaves Extract (Gleichenia linearis) as Bioinsecticide on Mortality of Black Ant (Dolichoderus thoracicus) 羊齿蕨叶提取物对胸黑蚁死亡率的影响

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2022-12-17 DOI: 10.58549/nsmrj.v1i1.22

Chandra Halim, Wahdana Apriyani, Reh Desiva Christima Br Ginting, Dita Ariyani, Amirul Mirdas

{"title":"Effectiveness of Resam Fern Leaves Extract (Gleichenia linearis) as Bioinsecticide on Mortality of Black Ant (Dolichoderus thoracicus)","authors":"Chandra Halim, Wahdana Apriyani, Reh Desiva Christima Br Ginting, Dita Ariyani, Amirul Mirdas","doi":"10.58549/nsmrj.v1i1.22","DOIUrl":"https://doi.org/10.58549/nsmrj.v1i1.22","url":null,"abstract":"Insecticides are type of pesticide used to eradicate or control pests. Generally, there are two types of insecticides, namely natural and synthetic insecticides. Natural insecticides are scarce due to their inability to eradicate pests such as black ants. Meanwhile, the use of synthetic insecticides is very practical and fast but can cause pollution that is harmful to humans, animals and other living things. Thus, natural insecticides are needed that can eradicate black ants effectively and efficiently and do not pollute the environment or poison other organisms. The research method used is combination of experimental methods, observation, and literature studies. In determining the best insecticide variation for mortality, a black ant mortality rate was measured using timer for 50 black ants. After the data was obtained, it was analyzed descriptively to determine the value of the mortality rate for each experimental sample. Based on the data obtained, the best variation of natural insecticides was the control variation of fern leaf extract with 3.646 seconds per ant. This is because fern leaf extract in insecticides contains tannin compounds which have several benefits as active pesticide ingredients. Thus, fern insecticides are effective in exterminating black ants.","PeriodicalId":365569,"journal":{"name":"NSMRJ: Nusantara Scientific Medical Research Journal","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115164572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improved Quality of Spermatozoa Mice (Mus musculus) Model of Diabetes Mellitus Type 1 After Being Given Cinnamon Bark Methanol Extract (Cinnamomum burmanii Bl.) 肉桂皮甲醇提取物对1型糖尿病精小鼠模型质量的影响

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2022-12-17 DOI: 10.58549/nsmrj.v1i1.27

A. M. Ukratalo, Titus Frendi Wedilen, Ian Risaldy Tofure, Dodikrisno Ekaputra Manery, Muhammad Reza Ramadhany

{"title":"Improved Quality of Spermatozoa Mice (Mus musculus) Model of Diabetes Mellitus Type 1 After Being Given Cinnamon Bark Methanol Extract (Cinnamomum burmanii Bl.)","authors":"A. M. Ukratalo, Titus Frendi Wedilen, Ian Risaldy Tofure, Dodikrisno Ekaputra Manery, Muhammad Reza Ramadhany","doi":"10.58549/nsmrj.v1i1.27","DOIUrl":"https://doi.org/10.58549/nsmrj.v1i1.27","url":null,"abstract":"Diabetes mellitus has to do with male fertility, a hormone disorder that affects spermatogenesis. This study aims to determine the effect of cinnamon bark methanol extract (Cinnamomum burmani) on the quality of diabetes mellitus mice spermatozoa. This study used a complete randomized design with 4 treatments and 3 repeats. 22 mice were divided into 4 groups. Mice have injected with streptozotocin dose of 0.1 mL and observed blood sugar levels were, if sugar levels increased, they are given cinnamon bark methanol extract at a dose of 250 mg/kg BB and 500 mg/kg BB, and blood sugar levels are measured. After that, the mice are dissected for observation of spermatozoa's morphology, viability, and motility after administration of the extract. The results showed that cinnamon bark methanol extract at a dose of 250 mg/kg BB and 500 mg/kg BB can reduce the number of abnormal spermatozoa and increase the viability and motility of diabetes mellitus mice spermatozoa. This indicates that cinnamon bark extract as an antioxidant has a positive effect in maintaining structure and development, as well as the function of spermatogenesis cells so that in the presence of these active substances, the number of seed cells that experience developmental failure, degeneration, death due to free radicals can be suppressed or reduced.","PeriodicalId":365569,"journal":{"name":"NSMRJ: Nusantara Scientific Medical Research Journal","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123794000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Organeleptic Test for Fortified Packaging Milk by Utilizing Calcium from Egg Shell Waste 利用蛋壳废钙强化包装奶的感官试验

NSMRJ: Nusantara Scientific Medical Research Journal Pub Date : 2022-12-17 DOI: 10.58549/nsmrj.v1i1.21

Chandra Halim, M. Fadli, Dicki Darmawan, Dwinta Nurul Fadillah Bintang, Farhan Rahmadani

{"title":"Organeleptic Test for Fortified Packaging Milk by Utilizing Calcium from Egg Shell Waste","authors":"Chandra Halim, M. Fadli, Dicki Darmawan, Dwinta Nurul Fadillah Bintang, Farhan Rahmadani","doi":"10.58549/nsmrj.v1i1.21","DOIUrl":"https://doi.org/10.58549/nsmrj.v1i1.21","url":null,"abstract":"In terms of national needs, the necessity for eggs reached 4,742,240 tons employing massive impact on the production of egg shell waste. Nevertheless, packaging milk released in the market contains low calcium and unsatisfies the nutritional needs of adult calcium, namely 1000 mg/day. Therefore, it is necessary to add waste of calcium-rich egg shells so the nutritional needs of calcium can be fulfilled and reduces the egg shell waste at the same time. The research method used is combination of experimental methods, interviews, and literature study. The data is analyzed by using descriptive statistics and non-parametric statistical tests to draw conclusions. Based on the data obtained, the best variation is the milk control with a total value of 580 points, 33 points different from 2:1 variation. The giving of egg shell waste reduces the milk aroma which is preferable for people who dislike its aroma. Through non-parametric statistical tests, it was investigated that there was no significant difference in adding egg shell flour to make fortified milk except for egg shell control. Therefore, egg shell flour can be used as additional material to enrich the calcium, to reduce the milk aroma and the amount of organic waste in Indonesia.","PeriodicalId":365569,"journal":{"name":"NSMRJ: Nusantara Scientific Medical Research Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121776004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0