Gynecology最新文献

筛选
英文 中文
Contraception after childbirth: current achievements and prospects: A review 产后避孕:当前成就与前景:综述
Gynecology Pub Date : 2024-05-09 DOI: 10.26442/20795696.2024.1.202605
V. Prilepskaya, E. G. Nazarenko
{"title":"Contraception after childbirth: current achievements and prospects: A review","authors":"V. Prilepskaya, E. G. Nazarenko","doi":"10.26442/20795696.2024.1.202605","DOIUrl":"https://doi.org/10.26442/20795696.2024.1.202605","url":null,"abstract":"The article presents modern methods of contraception after childbirth, including their impact on the mother and child, the main advantages and disadvantages. Special attention is paid to barrier methods of contraception, spermicides, and their advantages according to the \"Acceptance Criteria\" of the World Health Organization (2015) and the \"National Acceptance Criteria\" (2023), their features and prospects for use.","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":" 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140995956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gonadotropins in assisted reproductive technology programs: A review 辅助生殖技术项目中的促性腺激素:综述
Gynecology Pub Date : 2024-05-09 DOI: 10.26442/20795696.2024.1.202531
S. Ostrina, O. F. Serova, E. B. Rudakova, E. A. Fedorova
{"title":"Gonadotropins in assisted reproductive technology programs: A review","authors":"S. Ostrina, O. F. Serova, E. B. Rudakova, E. A. Fedorova","doi":"10.26442/20795696.2024.1.202531","DOIUrl":"https://doi.org/10.26442/20795696.2024.1.202531","url":null,"abstract":"Reproductive medicine is actively developing, and new methods, drugs, and protocols are being developed and introduced for the treatment of infertility. Assisted reproductive technologies (ART) are the most effective methods. In ART protocols, ovarian stimulation (OS) is based on gonadotropin use. The choice of the starting dose of gonadotropin is a critical factor in the successful OS and the effectiveness of ART programs. The article describes the development history of gonadotropins and provides current data on their use in ART programs. The use of biosimilars of follitropin alfa in OS is discussed, and the effectiveness of its Russian biosimilar is also addressed. \u0000 \u0000 \u0000 \u0000 \u0000TRANSLATE with x \u0000 \u0000 English \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000Arabic \u0000Hebrew \u0000Polish \u0000 \u0000 \u0000Bulgarian \u0000Hindi \u0000Portuguese \u0000 \u0000 \u0000Catalan \u0000Hmong Daw \u0000Romanian \u0000 \u0000 \u0000Chinese Simplified \u0000Hungarian \u0000Russian \u0000 \u0000 \u0000Chinese Traditional \u0000Indonesian \u0000Slovak \u0000 \u0000 \u0000Czech \u0000Italian \u0000Slovenian \u0000 \u0000 \u0000Danish \u0000Japanese \u0000Spanish \u0000 \u0000 \u0000Dutch \u0000Klingon \u0000Swedish \u0000 \u0000 \u0000English \u0000Korean \u0000Thai \u0000 \u0000 \u0000Estonian \u0000Latvian \u0000Turkish \u0000 \u0000 \u0000Finnish \u0000Lithuanian \u0000Ukrainian \u0000 \u0000 \u0000French \u0000Malay \u0000Urdu \u0000 \u0000 \u0000German \u0000Maltese \u0000Vietnamese \u0000 \u0000 \u0000Greek \u0000Norwegian \u0000Welsh \u0000 \u0000 \u0000Haitian Creole \u0000Persian \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000TRANSLATE with \u0000 \u0000 COPY THE URL BELOW \u0000 \u0000 Back \u0000 \u0000 \u0000EMBED THE SNIPPET BELOW IN YOUR SITE \u0000 \u0000Enable collaborative features and customize widget: Bing Webmaster Portal \u0000Back","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":" 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140996419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of hyaluronic acid based bulking agent for stress urinary incontinence in women: A prospective controlled study 使用基于透明质酸的膨润剂治疗女性压力性尿失禁:前瞻性对照研究
Gynecology Pub Date : 2024-05-09 DOI: 10.26442/20795696.2024.1.202623
Maria M. Zhevlakova, E. Rusina, E. Shelaeva, M. Yarmolinskaya
{"title":"The use of hyaluronic acid based bulking agent for stress urinary incontinence in women: A prospective controlled study","authors":"Maria M. Zhevlakova, E. Rusina, E. Shelaeva, M. Yarmolinskaya","doi":"10.26442/20795696.2024.1.202623","DOIUrl":"https://doi.org/10.26442/20795696.2024.1.202623","url":null,"abstract":"Background. Paraurethral injection of bulking agents in women is one of the minimally invasive technologies for the treatment of stress urinary incontinence (SUI). The effectiveness and safety of this method depend on the properties of injected substance. \u0000Aim. To evaluate the results of paraurethral injections of 1,4-butanediol diglycidyl ether crosslinked high-density hyaluronic acid (EsteFILL® intim) in the treatment of SUI in women of reproductive and perimenopausal age. \u0000Materials and methods. We examined 18 patients aged 45.8±5.0 years with mild SUI in combination with grade I–II genital prolapse. After general clinical and special studies (urination diaries, King and PISQ-12 questionnaires, cough test, complex urodynamic study, urethrovesical segment and pelvic floor ultrasound with compression elastography) paraurethral injection of 4.0 ml EsteFILL® intim drug was performed. The results of therapy were studied 1 and 6 months after the procedure. \u0000Results. It was found that the injection of the drug contributed to an increase in the stiffness of paraurethral tissues by 1.5 times within 6 months after injection. According to the results of elastography before treatment, the average value of the strain ratio of paraurethral tissues of the proximal posterior wall of the urethra was 0.66±0.46 (0.42–0.91), after 1 and 6 months – 0.99±0.45 (0.76–1.23) and 1.00±0.36 (0.78–1.22) respectively; p=0.009 and 0.018. The effectiveness of EsteFILL® intim drug in the treatment of mild SUI in women after 1 and 6 months according to the results of a cough test was 88.2 and 71.4%, according to urination diaries – 88.9 and 66.7% respectively. During the entire observation period the patients noted a decrease in the degree of discomfort due to SUI and an improvement in the quality of life. \u0000Conclusion. Paraurethral injection of EsteFILL® intim drug helps to increase the stiffness of the urethra supporting structures in patients with SUI. This method of treating SUI is effective for women of reproductive and perimenopausal age with mild severity disease, who do not plan surgical treatment, are interested in achieving a quick result of therapy and are informed that the effect decreases over time after the procedure.","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":" 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140996637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual health of women using combined oral contraceptive containing estetrol and drospirenone: A prospective observational study 使用含有雌二醇和屈螺酮的复方口服避孕药的妇女的性健康:前瞻性观察研究
Gynecology Pub Date : 2024-05-09 DOI: 10.26442/20795696.2024.1.202568
M. R. Orazov, V. Radzinskiy, M. Khamoshina, R. E. Orekhov, V. V. Ermakov
{"title":"Sexual health of women using combined oral contraceptive containing estetrol and drospirenone: A prospective observational study","authors":"M. R. Orazov, V. Radzinskiy, M. Khamoshina, R. E. Orekhov, V. V. Ermakov","doi":"10.26442/20795696.2024.1.202568","DOIUrl":"https://doi.org/10.26442/20795696.2024.1.202568","url":null,"abstract":"Aim. To evaluate the effect of a combined oral contraceptive (COC) containing estetrol and drospirenone on the sexual function of women using it. \u0000Materials and methods. A total of 251 women aged 21–35 years (mean age, 25.30±2.82 years) referred for contraceptive fitting were included in the study (ICD-10: Z30.0 General contraceptive advice and counseling, Z30.4 Contraceptive drug monitoring). Women in the study cohort used the original formulation containing 15 mg estetrol and 3 mg drospirenone in a 24+4 regimen for contraceptive purposes, according to the current instructions. All female participants (n=251) were assessed for sexual function at baseline, 6 and 12 months using FSFI (The Female Sexual Function Index), FSDS-R (The Female Sexual Distress Scale-Revised) and SQoL-F (The Sexual Quality of Life-Female) scales. \u0000Study design. An open, independent, prospective observational study. \u0000Results. Women taking COC containing estetrol 15 mg and drospirenone 3 mg maintained a baseline high level of sexual satisfaction (p0.05) throughout the study, as assessed by FSFI, SQoL-F and FSDS-R scales. \u0000Conclusion. The results obtained indicate that there is no negative effect of COC containing 15 mg estetrol and 3 mg drospirenonone on the sexual function of women. High contraceptive efficacy of the drug was confirmed.","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140995760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uterine artery embolization in the treatment of uterine fibroids and the preservation of reproductive health in women 40 years of age and older: A retrospective study 子宫动脉栓塞术在治疗子宫肌瘤和保护 40 岁及以上女性生殖健康方面的应用:回顾性研究
Gynecology Pub Date : 2024-05-09 DOI: 10.26442/20795696.2024.1.202414
A. V. Solovyeva, L. Chegus, E. Aleynikova, S. Semenchenko, Oksana I. Menshikh, A. Kasparova
{"title":"Uterine artery embolization in the treatment of uterine fibroids and the preservation of reproductive health in women 40 years of age and older: A retrospective study","authors":"A. V. Solovyeva, L. Chegus, E. Aleynikova, S. Semenchenko, Oksana I. Menshikh, A. Kasparova","doi":"10.26442/20795696.2024.1.202414","DOIUrl":"https://doi.org/10.26442/20795696.2024.1.202414","url":null,"abstract":"Aim. To evaluate the effect of uterine artery embolization (UAE) on reproductive health in women 40 years and older. \u0000Materials and methods. A retrospective study was conducted at the perinatal center of the District Clinical Hospital of Khanty-Mansiysk. Patients were divided into two groups: the main group (group 1; n=57) included women with uterine fibroids after UAE, and the control group (group 2; n=42) included women without a history of uterine fibroids. \u0000Results. Women with uterine fibroids were statistically more likely to have grade 1 obesity (χ2=4.39; p=0.04) and less likely to have normal body weight (χ2=8.73; p=0.00) compared to women without fibroids. Smoking increased the risk of uterine fibroids twofold (χ2=4.49; p=0.03; odds ratio 1.97; confidence interval 0.64-6.11). More women with uterine fibroids had a history of abortions (n=42; 73.7%) than those without uterine fibroids (n=19; 45.2%; χ2=8.27; p=0.01). The most common gynecological comorbidities in women with uterine fibroids included inflammatory disease of the uterus (N71), endometrial polyp (N84), and endometriosis (N80); p0.05. The most common extragenital diseases in patients with uterine fibroids included thyroid disease, hypertension, and iron deficiency anemia (p0.05). Contour SE embolization agent with spherical particles was more often associated with pain (χ2=0.18; p=0.67) and less often with fever (χ2=4.47; p=0.03). There was a decrease in the number of short menstrual cycles (less than 24 days) from the moment before surgical treatment and after 24 months (χ2=34.580; p0.001) and an increase in the number of cycles of 24–38 days (χ2=14.887; p=0.005). At 24 months after UAE, there were more women with a menstrual period of less than 3 days (χ2=10.385; p=0.035) and fewer with a menstrual period of more than 8 days (χ2=34.573; p0.001). Ultrasound showed a decreased ovarian reserve at 6, 12 and 24 months after UAE (p0.05). \u0000Conclusion. When assessing the reproductive health of women 40 years and older after embolization of the uterine arteries, it was found that this method of treatment of symptomatic uterine fibroids leads to a decrease in the duration and heaviness of menstruation but increases the risk of an ovarian reserve decrease.","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140997118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current view of the management of patients with endometrial hyperplasia: A review 子宫内膜增生症患者的治疗现状:综述
Gynecology Pub Date : 2024-05-09 DOI: 10.26442/20795696.2024.1.202654
A.S. Khachatryan, Y. Dobrokhotova, Irina Yu. Il'ina, S.N. Kazantsev
{"title":"Current view of the management of patients with endometrial hyperplasia: A review","authors":"A.S. Khachatryan, Y. Dobrokhotova, Irina Yu. Il'ina, S.N. Kazantsev","doi":"10.26442/20795696.2024.1.202654","DOIUrl":"https://doi.org/10.26442/20795696.2024.1.202654","url":null,"abstract":"Endometrial hyperplasia (EH) is a spectrum of morphological changes in the endometrium characterized by the proliferation of glands and an increase in the gland-stromal ratio. The relevance of this disease is due to its high prevalence (10–55%). The clinical significance of EH is related to the increased risk of endometrioid cancer. One of the leading causes of EH is absolute or relative hyperestrogenism and progesterone deficiency that does not eliminate the proliferative effect of estrogens. The risk group for EH includes women with early menarche, late menopause, infertility, anovulation, polycystic ovary syndrome, obesity, type 2 diabetes mellitus, hypertension, Lynch syndrome, estrogen-producing ovarian tumors, as well as those receiving estrogen monotherapy or tamoxifen. Most leading experts believe that therapy should include surgery followed by drug therapy aimed at eliminating risk factors to reduce the risk of EH recurrence. Despite numerous research findings demonstrating the benefits of a particular treatment modality and the consequent presence of these modalities in clinical guidelines, the potential benefits of alternative therapies are still being discussed. This issue requires further study and the selection of optimal treatment regimens for patients with EH.","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140997094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uterine microbiome in women with uterine scar defect after cesarean section: Prospective cohort study 剖宫产术后瘢痕缺损妇女的子宫微生物组:前瞻性队列研究
Gynecology Pub Date : 2023-10-04 DOI: 10.26442/20795696.2023.3.202353
Anna A. Michelson, Margarita I. Telyakova, Maria V. Lazukina, Guzel N. Chistyakova, Aleksandr V. Ustyuzhanin, Anatoly N. Varaksin, Tatyana A. Maslakova, Ekaterina D. Konstantinova
{"title":"Uterine microbiome in women with uterine scar defect after cesarean section: Prospective cohort study","authors":"Anna A. Michelson, Margarita I. Telyakova, Maria V. Lazukina, Guzel N. Chistyakova, Aleksandr V. Ustyuzhanin, Anatoly N. Varaksin, Tatyana A. Maslakova, Ekaterina D. Konstantinova","doi":"10.26442/20795696.2023.3.202353","DOIUrl":"https://doi.org/10.26442/20795696.2023.3.202353","url":null,"abstract":"Aim. To evaluate the endometrial microbiota in patients with uterine scar defect after cesarean section.
 Materials and methods. The study included 80 women of reproductive age. The main group included 50 patients with a uterus scar defect due to cesarean section; the comparison group included 30 women with a competent uterus scar due to cesarean section. Patients underwent a Pipelle endometrial biopsy on days 2022 of the menstrual cycle using a double-lumen catheter that excludes sample contamination with vaginal and cervical microflora. A molecular genetic study of the endometrium was performed by real-time polymerase chain reaction using the Femoflor 16 reagent kit (DNA-Technology
 Moscow). The DNA content in the specimen was measured using software and expressed in genome equivalent (GE) proportional to the number of microorganisms. The statistical data were processed using the Exсel software package and SPSS Statistics 22.0.
 Results. The study showed the following statistically significant differences: lower count of Lactobacillus spp. 2.600 (1.4303.600) GE/mL vs 3.550 (2.8004.700) GE/mL in patients of the comparison group (p=0.02); higher count of Streptococcus and Staphylococcus spp. 3.270 (3.0003.700) GE/mL and 3.450 (3.2003.600) GE/mL vs 1.030 (0.7601.700) GE/mL and 0.560 (0.1201.200) GE/mL in the comparison group, respectively (p0.00001); higher count of Enterobacteriaceae 2.700 (1.7003.300) GE/mL vs 0.950 (0.6601.120) GE/mL in the comparison group (p0.00001); higher count of Gardnerella/Prevotellabivia/Porphyromonas spp. 2.310 (0.9303.480) GE/mL vs 1.000 (0.0001.860) GE/mL (p=0.003); higher count of Peptostreptococcus spp. 0.195 (0.0001.560) GE/mL vs 0.000 (0.000-0.000) GE/mL (p=0.032); Eubacterium spp. 1.355 (0.1002.460) GE/mL vs 0.000 (0.0001.560) GE/mL (p=0.040).
 Conclusion. Endometrial dysbiosis in patients with a uterus scar defect after cesarean section due to the possible effects of microorganisms can be considered one of the leading causes of the formation of a uterus scar defect in the postoperative period.","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135644646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular genetic determinants of stress urinary incontinence in women: Prospective comparative study 女性压力性尿失禁的分子遗传决定因素:前瞻性比较研究
Gynecology Pub Date : 2023-10-04 DOI: 10.26442/20795696.2023.3.202354
Anna A. Mikhelson, Evgenia V. Lugovykh, Maria V. Lazukina, Tatiana B. Tretyakova, Anatoly N. Varaksin, Ekaterina D. Konstantinova
{"title":"Molecular genetic determinants of stress urinary incontinence in women: Prospective comparative study","authors":"Anna A. Mikhelson, Evgenia V. Lugovykh, Maria V. Lazukina, Tatiana B. Tretyakova, Anatoly N. Varaksin, Ekaterina D. Konstantinova","doi":"10.26442/20795696.2023.3.202354","DOIUrl":"https://doi.org/10.26442/20795696.2023.3.202354","url":null,"abstract":"Aim. To identify the molecular genetic determinants of stress urinary incontinence (UI) in women.
 Materials and methods. A comparative study involving 120 women was conducted. Group 1 (main group) included 80 women with UI. Group 2 (comparison group) included 40 women without UI. Statistic data processing was performed using the Excel software package, SPP Statistics 22.0, Statistica for Windows 10 (TIBCO Software Inc., Palo Alto, CA, USA). The mean and standard deviation were reported for quantitative variables with a normal distribution. The statistical hypotheses on the absence of intergroup differences for quantitative variables with normal distribution were verified using Student's test. The absolute and relative values (in percent) were reported for qualitative variables. The chi-square test was used to verify the statistical hypotheses.
 Results. Molecular genetic predictors of UI in women are the carriage of polymorphisms of the estrogen receptor gene ESR1:-351_G and the type I collagen gene COL1A1:1546_T. These polymorphisms can be considered as genotypes of \"risk\" since their carriage is associated with an increased risk of UI.
 Conclusion. Genetically determined disorders of the estrogen receptor function and type I collagen synthesis can be one of the essential mechanisms of stress incontinence occurrence. Studying molecular genetic determinants of stress incontinence can provide a deeper understanding of its pathogenetic mechanisms and develop a personalized approach to surgical correction.","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135644090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for in vitro fertilization failures in women with adenomyosis-associated infertility 子宫腺肌病相关性不孕妇女体外受精失败的危险因素
Gynecology Pub Date : 2023-10-04 DOI: 10.26442/20795696.2023.3.202379
Mekan R. Orazov, Liudmila M. Mikhaleva, Viktor E. Radzinskiy, Marina B. Khamoshina, Abecha K. Barinova, Dmitry G. Aryutin, Marina V. Tsaregorodtseva, Irina V. Besman, Vafa Yu. Ibragimova
{"title":"Risk factors for in vitro fertilization failures in women with adenomyosis-associated infertility","authors":"Mekan R. Orazov, Liudmila M. Mikhaleva, Viktor E. Radzinskiy, Marina B. Khamoshina, Abecha K. Barinova, Dmitry G. Aryutin, Marina V. Tsaregorodtseva, Irina V. Besman, Vafa Yu. Ibragimova","doi":"10.26442/20795696.2023.3.202379","DOIUrl":"https://doi.org/10.26442/20795696.2023.3.202379","url":null,"abstract":"Aim. To identify risk factors for in vitro fertilization (IVF) failures in women with adenomyosis-associated infertility.
 Materials and methods. The study included 83 patients of reproductive age with adenomyosis. Women were divided into two groups: the main group (n=53) included patients with adenomyosis and a history of 1 or more unsuccessful attempts at embryo transfer, and the comparison group (n=30) included women with adenomyosis without impaired fertile function. The mean age of the patients was 364.0 years.
 Results. Gynecological conditions such as cervical dysplasia, noninflammatory vaginal diseases, and a history of sexually transmitted infections (STIs) were significantly (5-fold) more common in patients with a history of IVF failures (p0.05). A high prevalence of endocrine and digestive system disorders (27.7 and 7.7 times, respectively) was found in infertile women with adenomyosis (p0.05). Coagulation disorders were identified 4.8 times more often in women with adenomyosis-associated infertility and IVF failures. Inflammatory and proliferative endometrial diseases (hyperplasia, intrauterine synechia, and chronic endometritis) were significantly more common in patients in the main group than in patients with adenomyosis without impaired fertility (p0.05).
 Conclusion. Risk factors for IVF failure in women with adenomyosis-associated infertility are other specified coagulation defects [D68.8] (antiphospholipid syndrome), odds ratio (OR) 4.8, 95% confidence interval (CI) 1.120.9; dysplasia of cervix uteri, unspecified [N87.9] (OR 10.2, 95% CI 1.292.4), other noninflammatory disorders of vagina [N89.7] (OR 10.2, 95% CI 1.292.4), STIs (OR 12.7, 95% CI 1.4112.5), endocrine system disorders (OR 27.7, 95% CI 1.5516.5), and digestive system disorders (OR 7.8, 95% CI 2.227.8).","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135590292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The birth of a healthy child in a married couple with a history of multiple unsuccessful attempts at ART by selecting sperm on oocyte-cumulus complexes. Case report 一对夫妇曾多次尝试通过卵-积云复合体选择精子,但没有成功,他们生下了一个健康的孩子。病例报告
Gynecology Pub Date : 2023-10-04 DOI: 10.26442/20795696.2023.3.202115
Alina V. Chistyakova, Alina A. Babayan, Alina А. Dovgan, Natalya P. Makarova, Natalya N. Lobanova, Veronika Yu. Smolnikova
{"title":"The birth of a healthy child in a married couple with a history of multiple unsuccessful attempts at ART by selecting sperm on oocyte-cumulus complexes. Case report","authors":"Alina V. Chistyakova, Alina A. Babayan, Alina А. Dovgan, Natalya P. Makarova, Natalya N. Lobanova, Veronika Yu. Smolnikova","doi":"10.26442/20795696.2023.3.202115","DOIUrl":"https://doi.org/10.26442/20795696.2023.3.202115","url":null,"abstract":"In male infertility, couples must use assisted reproductive technologies with the intracytoplasmic sperm injection (ICSI) technique. A significant disadvantage of ICSI is bypassing natural selection barriers since selective processes in the female reproductive tract are replaced by the choice of an embryologist based on sperm motility and morphological criteria. Various selection methods are being actively studied, bringing fertilization by ICSI closer to physiological, ensuring the selection of sperm with high DNA quality and good potential for fertilization. The article presents a clinical case of the birth of a healthy child in a married couple with severe male infertility and many ineffective attempts at assisted reproductive technologies using the method of sperm selection on oocyte-cumulus complexes. The child is physically healthy and develops according to age.","PeriodicalId":36505,"journal":{"name":"Gynecology","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135644372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信