{"title":"Extending the Reach of Colorectal Screening to all Populations in the United States","authors":"Seo Hyun Kim , Divya P. Prajapati , Samir Gupta","doi":"10.1016/j.tige.2024.03.003","DOIUrl":"10.1016/j.tige.2024.03.003","url":null,"abstract":"<div><p>In this narrative review, we provide an overview of the current reach of colorectal cancer (CRC) screening in the US population; how persistent inequities in CRC across age and sociodemographic groups and changes in epidemiology, as well as population structure, have increased the urgency of achieving optimal reach; and current and future strategies for optimizing the reach and impact of screening across the population. CRC screening saves lives, but reach across the population, including across age and sociodemographic groups, is highly variable. CRC screening participation in the United States remains at under 60% and has been stagnant over time. Lower screening participation is observed for individuals of younger age; of American Indian/Alaska Native, Asian, and Hispanic backgrounds; with Medicaid insurance; and with recent immigration. Addressing suboptimal reach is increasingly important due to changing CRC epidemiology and US population structure. Recent trends demonstrate increases in early (<50 years) and middle age (50-60 years) onset of CRC and nonlocalized-stage CRC, as well as persistent inequities in CRC outcomes among multiple racial/ethnic groups. These trends exist in a context where the US population is increasingly composed of individuals from diverse backgrounds associated with lower screening rates and higher rates of adverse CRC outcomes. Screening reach can be optimized by building on successes of previous impactful policies, implementing evidence-based interventions for screening, and developing novel strategies that address challenges at patient, clinician, healthcare system, and policy levels. Gastroenterologists, other clinicians, and public health advocates have a major role in leading positive change at each of these levels. Overall, the need to optimize the reach of CRC screening represents a pressing opportunity for improving health equity across all populations in the United States.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"26 2","pages":"Pages 153-166"},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590030724000175/pdfft?md5=a559ef75ac2e110d0900ec33d59ea3b9&pid=1-s2.0-S2590030724000175-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140272497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preface: Barrett's Esophagus","authors":"Vani J.A. Konda","doi":"10.1016/j.tige.2023.01.005","DOIUrl":"https://doi.org/10.1016/j.tige.2023.01.005","url":null,"abstract":"","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 2","pages":"Page 105"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49750070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Umer Farooq , Raymond Lee , Diana Franco , Ayokunle T. Abegunde
{"title":"Health Literacy Does Not Influence the Selection of Colorectal Cancer Screening Methods: A Cross-Sectional Analysis","authors":"Umer Farooq , Raymond Lee , Diana Franco , Ayokunle T. Abegunde","doi":"10.1016/j.tige.2022.11.003","DOIUrl":"https://doi.org/10.1016/j.tige.2022.11.003","url":null,"abstract":"","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 2","pages":"Pages 189-191"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49750406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leontien M.G. Nijland , Kevin E.J. van den Brule , Ruben N. van Veen , Pim W. van Rutte , Sjoerd D. Kuiken , Steve M.M. de Castro
{"title":"The Yield of Preoperative Esophagogastroduodenoscopy in Patients Undergoing Bariatric Surgery After Gastric Banding","authors":"Leontien M.G. Nijland , Kevin E.J. van den Brule , Ruben N. van Veen , Pim W. van Rutte , Sjoerd D. Kuiken , Steve M.M. de Castro","doi":"10.1016/j.tige.2023.02.002","DOIUrl":"https://doi.org/10.1016/j.tige.2023.02.002","url":null,"abstract":"<div><h3>Background and Aims</h3><p><span>Esophagogastroduodenoscopy (EGD) is routinely performed </span>in patients<span><span> who undergo conversion from adjustable gastric banding to another </span>bariatric procedure (eg, gastric bypass) of band removal. Band erosion is the main concern in these patients. The objective of this study was to analyze the yield of EGD in these patients.</span></p></div><div><h3>Methods</h3><p>All patients between 2008 and 2020 who underwent bariatric surgery<span> with an adjustable gastric band in place were included. Results of EGD were analyzed retrospectively and categorized according to clinical consequences.</span></p></div><div><h3>Results</h3><p><span>Overall, 514 patients (62 male, 452 female; mean age 46 years; mean BMI 40) underwent surgery with an adjustable gastric band in situ. In total, 488 patients (95%) underwent preoperative EGD. No abnormalities were found in 205 patients (42%), 112 patients (23%) had abnormalities without treatment consequences, 156 patients (32%) had findings that required pharmaceutical (ie, </span>proton pump inhibitors<span> and/or antibiotics) intervention, and 15 patients (3.1%) had severe findings altering management (group D). In 5 of these patients (1.0%), surgery was postponed due to Barrett's esophagus<span>, and 10 of these patients (2.0%) had gastric band erosion. No subgroup of patients could be identified to increase the yield of the EGD.</span></span></p></div><div><h3>Conclusion</h3><p>Routine preoperative assessment by EGD in patients before bariatric surgery with an adjustable gastric band in situ still detects some severe abnormalities significantly altering management.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 4","pages":"Pages 302-306"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49765272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Horizon of Screening for Barrett's Esophagus and Esophageal Cancer","authors":"W. Keith Tan , Rebecca C. Fitzgerald","doi":"10.1016/j.tige.2023.01.004","DOIUrl":"https://doi.org/10.1016/j.tige.2023.01.004","url":null,"abstract":"<div><p>Barrett's esophagus (BE) is a premalignant precursor to esophageal adenocarcinoma (EAC), a cancer whose incidence has increased sixfold in the Western world over the past 3 decades. The prognosis associated with EAC remains poor, with the 5-year survival estimated to be < 20%. Epidemiological and clinical study evidence has suggested that early detection and treatment of BE-related neoplasia is associated with improved survival, suggesting that screening for this condition could impact EAC survival. Over the past few decades, there have been accelerated advances in the field of BE and EAC, particularly in the emergence of non-endoscopic cell-collection devices that could be used for screening. In this review, we critically discuss the concept of screening BE and EAC, as well as identifying the target population who should be screened. We then review the evidence for various cell-collection devices that could be used for screening in the office-based setting, such as screenig using prediction models, transnasal endoscopy (TNE), Cytosponge and biomarker Trefoil-factor 3 (TFF3), EsophaCap and methylated DNA markers (MDMs), and the balloon-based EsoCheck and MDMs. We also discuss other novel technologies, such as volatile organic compound detection using the electric nose and technologies using optical coherence tomography. These promising technologies have paved the way for the potential introduction of a screening program for BE and EAC, with the hope that this could lead to improved outcomes among patients who suffer from this unfortunate disease.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 2","pages":"Pages 146-156"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49765364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saurabh Chandan , Jay Bapaye , Daryl Ramai , Antonio Facciorusso
{"title":"Surveillance Colonoscopy After Polypectomy—Current Evidence and Future Directions","authors":"Saurabh Chandan , Jay Bapaye , Daryl Ramai , Antonio Facciorusso","doi":"10.1016/j.tige.2023.02.004","DOIUrl":"https://doi.org/10.1016/j.tige.2023.02.004","url":null,"abstract":"<div><p><span>Colorectal cancer (CRC) incidence continues to steadily rise in various parts of the world, and there remains an urgent need for effective interventions to tackle this. Effective and timely implementation of CRC screening interventions and adherence to post </span>polypectomy<span><span> surveillance recommendations remain paramount. Colonoscopy<span> is the gold standard for timely diagnosis and removal of precursor lesions or polyps to CRC; however, patient uptake and cost effectiveness, especially in the era of noninvasive testing strategies, require closer evaluation. Furthermore, the risk of progression to CRC varies with the morphology, size, and histology of </span></span>colorectal polyps. Several colonoscopy-based resection techniques have been reported in literature to effectively and safely remove these precursor lesions. In this review, we summarize the current guidelines (US and Europe) and evidence for the effectiveness of post-polypectomy surveillance, resection, and surveillance for sessile serrated lesions. We also appraise the current literature regarding non-colonoscopy options for post colonoscopy surveillance, as well as interventions to boost adherence to surveillance.</span></p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 3","pages":"Pages 269-283"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49767287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas M. McDonald , Mohammad Bilal , Nabeel Azeem, Stuart K. Amateau
{"title":"Practice Patterns of Endoscopists Performing Endoscopic Gallbladder Drainage","authors":"Nicholas M. McDonald , Mohammad Bilal , Nabeel Azeem, Stuart K. Amateau","doi":"10.1016/j.tige.2023.03.005","DOIUrl":"https://doi.org/10.1016/j.tige.2023.03.005","url":null,"abstract":"<div><h3>Background and Aims</h3><p><span><span>The standard of care for treatment of patients with </span>acute cholecystitis<span><span> is cholecystectomy. However, many patients are unfit for surgery due to substantial medical comorbidities, or surgery is technically challenging due to anatomic considerations. Options for patients who are not surgical candidates include percutaneous </span>cholecystostomy tube placement by </span></span>interventional radiology<span><span>, endoscopic gallbladder drainage (EGBD), or conservative management. Over the last decade, techniques of EGBD have been employed for temporary or definitive gallbladder drainage </span>in patients with acute cholecystitis who are not surgical candidates. Despite growing interest and clinical use of EGBD, little is known about practice patterns of EGBD. Our aim was to survey endoscopists to evaluate the practice patterns and technical considerations regarding EGBD.</span></p></div><div><h3>Methods</h3><p>An 18-item survey was distributed to all members of the American Society of Gastrointestinal Endoscopy. Each response was included in the final analysis. Descriptive statistics were calculated using frequencies and percentages.</p></div><div><h3>Results</h3><p><span>Responses were received from 217 endoscopists. Of these, 178 perform endoscopic ultrasound-guided gallbladder draining and 178 perform endoscopic transpapillary gallbladder drainage. The preferred approach for EGBD was endoscopic ultrasound-guided gallbladder drainage in 58.8%, endoscopic retrograde cholangiopancreatography (ERCP)-guided transpapillary gallbladder </span>stent placement in 30.2%, and no preference in 11%.</p></div><div><h3>Conclusion</h3><p>Despite growing interest in EGBD, significant heterogeneity in practice patterns exists. Further study is needed to better understand these differences and provide data for future guidelines.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 3","pages":"Pages 221-227"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49749463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonja Boatman , Julia Kohn , Sarah L. Mott , Schelomo Marmor , Robert D. Madoff , Wolfgang B. Gaertner , Aasma Shaukat , Genevieve B. Melton , Imran Hassan , Paolo Goffredo
{"title":"The Prognostic Significance of Laterality in Endoscopically Resected Colonic Adenomas With High-Grade Dysplasia","authors":"Sonja Boatman , Julia Kohn , Sarah L. Mott , Schelomo Marmor , Robert D. Madoff , Wolfgang B. Gaertner , Aasma Shaukat , Genevieve B. Melton , Imran Hassan , Paolo Goffredo","doi":"10.1016/j.tige.2023.07.003","DOIUrl":"https://doi.org/10.1016/j.tige.2023.07.003","url":null,"abstract":"<div><h3>Background and Aims</h3><p><span><span>Advanced adenomas (AAs) with high-grade </span>dysplasia (HGD) represent risk factors for metachronous neoplasia, for which guidelines recommend short-interval endoscopic surveillance. Although worse survival of proximal </span>colon cancers has been established, the prognostic impact of laterality for AAs with HGD remains unknown. We hypothesized that proximal HGD would have a worse prognosis than distal lesions.</p></div><div><h3>Methods</h3><p><span>In this retrospective cohort study<span>, adults with HGD managed with endoscopic polypectomy were identified in the National Cancer Database from 2004-2017. Survival probabilities were estimated and plotted using the Kaplan-Meier method. </span></span>Cox regression models were used to assess the effect of adenoma laterality on overall survival (OS) while adjusting for patient and disease characteristics. One sample log-rank test was employed to compare the survival of patients with that of the US population.</p></div><div><h3>Results</h3><p>Of 3953 patients identified in the database, 29% had proximal lesions, which were more common in elderly, Black, publicly insured, and comorbid patients. Unadjusted 5- and 10-year OS was 81% and 67% for proximal vs 89% and 78% for distal HGD (<em>P</em> < 0.01). In multivariable analysis, proximal location did not demonstrate significantly worse OS (hazard ratio 1.09, 95% confidence interval [CI] 0.92-1.29). When compared with the age- and sex-matched US population, patients with HGD had significantly increased mortality (standardized mortality ratio 1.54, 95% CI 1.42-1.68), which was more pronounced for right-sided AAs.</p></div><div><h3>Conclusion</h3><p>Patients with HGD, particularly those with proximal lesions, had lower OS than the US population. Although proximal location was not independently associated with worse survival, OS may not represent the optimal endpoint for AAs given the low cancer incidence and effective treatment for early-stage tumors. Future research should focus on the risk of metachronous neoplasia to determine adequate surveillance protocols.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 4","pages":"Pages 352-360"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49749465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Managing Risk of Dysplasia and Colorectal Cancer in Inflammatory Bowel Disease","authors":"Juan Reyes Genere, Parakkal Deepak","doi":"10.1016/j.tige.2023.02.005","DOIUrl":"https://doi.org/10.1016/j.tige.2023.02.005","url":null,"abstract":"<div><p><span><span>Mitigating colorectal cancer (CRC) risk is a pillar in caring for patients with inflammatory bowel disease (IBD). Over the last decade, there have been significant advances in understanding the natural history of colitis-associated dysplasia (CAD) and its management. The identification of patient- and disease-specific risk factors has enabled a tailored approach to initiating </span>colonoscopy screening and surveillance programs. Improved video </span>endoscopy<span> systems and the development of advanced endoscopic resection techniques have evolved the role of endoscopy in CAD. Modern-era endoscopic instruments can better detect and effectively intervene with CAD, reducing CRC risk. As a result, the last decade has brought forth substantial changes to how endoscopic technologies are applied to IBD surveillance. This review will go over the latest updates in the stratification and management of CAD and CRC risk for patients with IBD, as well as discuss the exciting future in this topic area.</span></p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 4","pages":"Pages 372-384"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49749825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Future Directions for Robotic Endoscopy–Artificial Intelligence (AI), Three-Dimensional (3D) Imaging, and Natural Orifice Transluminal Endoscopic Surgery (NOTES)","authors":"Cem Simsek , Hung Leng Kaan , Hiroyuki Aihara","doi":"10.1016/j.tige.2022.10.001","DOIUrl":"https://doi.org/10.1016/j.tige.2022.10.001","url":null,"abstract":"<div><p><span>Artificial intelligence (AI) can aid endoscopic and surgical procedures in various ways, such as detecting and diagnosing gastrointestinal lesions, assisting in procedures, recognizing dissection planes, and predicting adverse events. 3D imaging has also improved the visual and technical aspects of endoscopic and surgical procedures by improving depth recognition. Robotic </span>endoscopy<span> involves aspects of both endoscopy and surgery. It is based on a flexible endoscopic technology; however, it allows for bimanual control of devices for better triangulation. Thus, AI and 3D imaging technologies should be incorporated into robotic endoscopy to improve learning curves and enable more precise operation of robotic instruments. The utilization of robotics will expand the spectrum of current therapeutic endoscopy. Natural orifice transluminal endoscopic surgery<span><span> (NOTES) is associated with shorter operative time, faster patient recovery, and less postoperative pain. However, current efforts to promote NOTES have been hampered by suboptimal NOTES surgical instruments, which have limited maneuverability and degrees of freedom. These challenges are overcome by the robotic </span>endoscope, which has end-effectors with high degrees of freedom. Surgeons performing NOTES using the robotic endoscope can perform triangulation and 360-degree rotation of the robotic wrists. As a 3-armed procedurist, the surgeon can now retract tissues effectively for optimal exposure of the operating field.</span></span></p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":"25 1","pages":"Pages 95-101"},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49749890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}