Techniques and Innovations in Gastrointestinal Endoscopy最新文献

{"title":"Reducing Disparities and Achieving Health Equity in Colorectal Cancer Screening","authors":"Abraham Segura ,&nbsp;Shazia Mehmood Siddique","doi":"10.1016/j.tige.2023.02.007","DOIUrl":"10.1016/j.tige.2023.02.007","url":null,"abstract":"<div><p><span>Increases in colorectal cancer screening are linked to the declining incidence of the disease over the past 3 decades. These favorable trends, however, are not observed in marginalized racial and ethnic populations with disproportionately lower rates of screening, higher disease incidence, and increased mortality, despite advances in </span>health technology and policy. This review describes the differences in screening uptake and test selection among racial and ethnic groups, discusses known obstacles and facilitators that impact screening, and highlights existing frameworks developed to achieve health equity in colorectal cancer screening.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10554575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41159653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to Quality Indicators for Diagnosis and Surveillance of Barrett's Esophagus: A Comparative Study of Barrett's Experts and Nonexperts","authors":"Domenico A. Farina ,&nbsp;Claire A. Beveridge ,&nbsp;Leila Kia ,&nbsp;Elizabeth Gray ,&nbsp;Srinadh Komanduri","doi":"10.1016/j.tige.2023.02.008","DOIUrl":"https://doi.org/10.1016/j.tige.2023.02.008","url":null,"abstract":"<div><h3>Background and Aims</h3><p>There is considerable variability in adherence to endoscopic quality indicators (QIs) for Barrett's esophagus (BE). The aims of this study were to (1) assess adherence to published Qis for diagnosis and surveillance of BE, (2) compare adherence between BE experts and nonexperts, and (3) identify factors associated with adherence.</p></div><div><h3>Methods</h3><p><span>We identified all patients with BE on esophagogastroduodenoscopy between 2010 and 2018. QIs evaluated included inspection using high-definition white light </span>endoscopy<span>, use of the Prague Classification, identification of endoscopic landmarks, use of the Seattle Protocol, and guideline-adherent recommendations for surveillance or endoscopic eradication therapy. BE experts and nonexperts were compared using logistic mixed-effects models.</span></p></div><div><h3>Results</h3><p>A total of 467 patients were identified, with BE experts performing fewer overall esophagogastroduodenoscopies (n = 162, 34.7% vs n = 305, 65.3%). Whereas BE experts were more likely to document Prague Classification (52.5% vs 41.3%; <em>P</em> = 0.017) and landmarks (43.2% vs 22.6%; <em>P</em><span> = 0.036), there was no significant difference between experts and nonexperts in use of high-definition white light endoscopy (8.6% vs 3.3%; </span><em>P</em> = 0.123), Seattle Protocol (48.1% vs 40.3%; <em>P</em><span> = 0.313), or guideline-adherent surveillance or treatment recommendations (71.0% vs 67.5%; </span><em>P</em> = 0.509). Patient enrollment in a BE surveillance program was the only factor associated with improved QI adherence, specifically adherence to Prague Classification documentation (OR 1.85, 95% CI 1.08-3.14; <em>P</em> = 0.025), Seattle Protocol (1.28, 95% CI 1.16-1.50; <em>P</em> &lt; 0.001), and follow-up recommendations (OR 2.64, 95% CI 1.55-4.48; <em>P</em> &lt; 0.001).</p></div><div><h3>Conclusion</h3><p>Patterns of adherence to published QIs for endoscopy in patients with BE are mostly independent of expertise. Further training initiatives are needed to standardize the performance of endoscopic practice in patients with BE.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49749694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polypectomy Techniques for Pedunculated and Nonpedunculated Polyps","authors":"Karl Kwok ,&nbsp;Sasan Mosadeghi ,&nbsp;Daniel Lew","doi":"10.1016/j.tige.2023.02.006","DOIUrl":"https://doi.org/10.1016/j.tige.2023.02.006","url":null,"abstract":"<div><p>Colonoscopic polypectomy<span>, when performed appropriately and completely, reduces subsequent risk of colorectal cancer. However, performance of high-quality polypectomy varies widely among endoscopists based on many factors, from exposure during fellowship to continuing education once in practice. Thus, this review is intended for a wide audience, from gastroenterology<span> trainees to practicing physicians. A review of electrosurgery principles is included to cover effective polypectomy techniques and to prevent and troubleshoot problems.</span></span></p><p>Similarly, successful colon polypectomy is heavily dependent on both anatomic position and endoscopic clock-face position within the colon. As a result, both equipment choice and hand technique are discussed, and specific tips are offered to maximize the likelihood of success. Additionally, within this review, we highlight several of the latest advances within the field of polypectomy, such as submucosal injection (including choice of fluid), dynamic injection technique, a thorough discussion on hot vs cold snare, site management, and complication management. Lastly, we explore why incomplete polypectomy occurs, the implications of incomplete polypectomy, and methods to reduce this risk.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49749839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Reported Adverse Events Related to Over-the-Scope Clips: A MAUDE Database Analysis","authors":"Daniyal Abbas ,&nbsp;Mohamed Abdallah ,&nbsp;Khalid Ahmed ,&nbsp;Abubaker O. Abdalla ,&nbsp;Nicholas McDonald ,&nbsp;Shifa Umar ,&nbsp;Brian J. Hanson ,&nbsp;Mohammad Bilal","doi":"10.1016/j.tige.2022.11.005","DOIUrl":"https://doi.org/10.1016/j.tige.2022.11.005","url":null,"abstract":"<div><h3>Background and Aims</h3><p>Over-the-scope clips (OTSCs) have been increasingly used in the management of bleeding, perforations, fistulae<span><span>, and anastomotic leaks in the </span>gastrointestinal tract. However, since their Food and Drug Administration (FDA) approval in 2010, data on the adverse events of OTSC systems have been lacking. The aim of our study was to report and analyze adverse events and device failures associated with OTSC systems using the FDA's Manufacturer and User Facility Device Experience (MAUDE) database.</span></p></div><div><h3>Methods</h3><p>We analyzed the FDA MAUDE database post-marketing surveillance data from January 2013 through May 2022 on the two OTSC systems available in the United States.</p></div><div><h3>Results</h3><p>Forty medical device reporting claims were found from January 2013 through May 2022. Adverse events were classified as device-related problems and patient-related adverse events. Forty device-related problems were reported, along with 20 device-related adverse events. Most device-related problems were reported in the Padlock defect closure system (n = 23), followed by the Padlock pro clip system (n = 8) and Ovesco OTSC system (n = 9). The most common device-related problem was related to the failure of OTSC deployment (n = 13), followed by material protrusion or extrusion (n = 7). The most common patient adverse events were perforation (n = 4), esophageal laceration (n = 4), bleeding (n = 3), and luminal stenosis (n = 3). All 4 patients required surgical management of the perforation. No deaths related to the use of OTSCs were reported.</p></div><div><h3>Conclusion</h3><p>Failure of OTSC deployment and perforation were the most common device-related problem and patient-related adverse event, respectively. As the use of OTSC systems continues to increase, it is important for endoscopists to be mindful of both the common and rare adverse events associated with OTSC use.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49750267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preface: Robotic Endoscopy–Current Engineering Developments, Clinical Applications, and Future Directions","authors":"Hung Leng Kaan ,&nbsp;Philip Wai Yan Chiu","doi":"10.1016/j.tige.2022.10.007","DOIUrl":"https://doi.org/10.1016/j.tige.2022.10.007","url":null,"abstract":"","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49750268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Events With Esophageal Stenting: A Call to Optimize Device and Endoscopic Placement","authors":"Devarshi R. Ardeshna ,&nbsp;Farah S. Hussain ,&nbsp;Gokulakrishnan Balasubramanian ,&nbsp;Georgios I. Papachristou ,&nbsp;Luis F. Lara ,&nbsp;J. Royce Groce ,&nbsp;Samuel Han ,&nbsp;Peter J. Lee ,&nbsp;Sajid Jalil ,&nbsp;Alice Hinton ,&nbsp;Somashekar G. Krishna","doi":"10.1016/j.tige.2022.09.001","DOIUrl":"https://doi.org/10.1016/j.tige.2022.09.001","url":null,"abstract":"<div><h3>Background and Aims</h3><p>Despite technological and procedural improvements, esophageal stents<span> (ESs) have high rates of adverse events (AEs), including stent migration<span>, recurrent stenosis, and chest pain. We sought to evaluate predictors and causes for early readmission following ES placement in hospitalized patients.</span></span></p></div><div><h3>Methods</h3><p>The National Readmission Database 2016-2018 was queried to identify hospitalized patients with an ICD-10-CM code for endoscopic ES placement. Primary outcome was early (≤ 30-day) readmission rate. Univariate and multivariable logistic regression models were used to evaluate predictors of early readmission.</p></div><div><h3>Results</h3><p><span><span>A total of 949 patients underwent index ES placement, and most (67%, n = 634) patients had benign indications. Overall, the most common indication was benign esophageal leak/fistula (n = 359), followed by malignant dysphagia from </span>esophageal neoplasm (n = 252). The 30-day readmission rate was 26% (n = 251), with higher rates for benign (29%) compared with malignant (22%) indications (</span><em>P</em> = 0.09). An analysis of primary diagnosis for early readmissions revealed that stent-related AEs were higher in the benign than in the malignant group (42% vs 23%, respectively; <em>P</em> = 0.008). Multivariable analysis revealed that ES placement for esophageal leak/fistulas (OR = 1.98; 95% CI, 1.20-3.24; <em>P</em> = 0.022) was the only significant variable associated with early readmission.</p></div><div><h3>Conclusion</h3><p>In recent years, inpatient ESs have been placed predominantly in patients with benign conditions, with esophageal leak/fistula being the most common indication. Stent-related AEs account for a significant burden of readmissions, particularly when placed for benign conditions. There is a need for focused research to refine indications, optimize techniques, and improve stent technology.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49750514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Endoscopic Biopsies for Determining Tumor Grade in Pre-resection Evaluation of Esophageal Adenocarcinoma","authors":"Ravi S. Shah ,&nbsp;Omar Alaber ,&nbsp;Xuefeng Zhang ,&nbsp;Abel Joseph ,&nbsp;Siva Raja ,&nbsp;Suneel Kamath ,&nbsp;Ruishen Lyu ,&nbsp;John J. Vargo ,&nbsp;Sudish C. Murthy ,&nbsp;Amitabh Chak ,&nbsp;Amit Bhatt","doi":"10.1016/j.tige.2023.06.001","DOIUrl":"https://doi.org/10.1016/j.tige.2023.06.001","url":null,"abstract":"<div><h3>Background and Aims</h3><p><span><span>Endoscopic resection<span> (ER) can be a curative treatment for early </span></span>esophageal adenocarcinoma (EAC). Poor tumor differentiation is a histologic feature of noncurative ER and, when seen on preoperative biopsies, may lead to avoidance of endoscopic treatment. However, the accuracy of tumor grade on preoperative </span>endoscopic biopsies remains unclear. The aim of this study was to determine the accuracy of tumor differentiation on endoscopic forceps biopsy compared with endoscopically or surgically resected tissue.</p></div><div><h3>Methods</h3><p>This retrospective cohort study from 2 tertiary referral centers compared tumor differentiation from preoperative biopsies with endoscopically or surgically resected EAC samples. Accuracy (%) of preoperative biopsy and agreement analyses (Gwet's AC2) were performed.</p></div><div><h3>Results</h3><p><span>In total, 346 EAC lesions (225 esophagectomies, 121 ERs) were included. The overall accuracy and reliability of EAC grade on preoperative biopsies compared with postoperative tissue from ER or esophagectomy was 74% (114/154), with a substantial agreement coefficient (Gwet's AC2 0.78 [0.72-0.85]; </span><em>P</em> &lt; 0.001). The accuracy of ER was only 56%, with moderate agreement (Gwet's AC2 0.60 [0.46-0.73]; <em>P</em> &lt; 0.001). Poorly differentiated tumors were downgraded to moderately differentiated in 19.6% (20/102) of tumors, and conversely, moderately differentiated tumors were upgraded to poorly differentiated in 22.7% (37/163) of tumors. For patients with T1a tumors, poorly differentiated tumors on preoperative biopsies were downgraded to moderately differentiated tumors in 40% (4/10) of cases after resection.</p></div><div><h3>Conclusions</h3><p>The accuracy of tumor grade of EAC on preprocedural biopsies is suboptimal and should not be depended upon solely to make decisions regarding endoscopic treatment.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49749691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confocal Laser Endomicroscopy Is a Useful Alternative “Optical” Biopsy Modality in Diagnosis of Gastric Intestinal Metaplasia","authors":"YUTAKA TOMIZAWA ,&nbsp;JOO HA HWANG ,&nbsp;BRYAN BALMADRID ,&nbsp;LISA STRATE","doi":"10.1016/j.tige.2022.07.004","DOIUrl":"https://doi.org/10.1016/j.tige.2022.07.004","url":null,"abstract":"","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49750273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Endoscopic Resection for Colorectal Polyps With High-Grade Dysplasia or Intramucosal Cancer","authors":"Sonmoon Mohapatra ,&nbsp;Erik Almazan ,&nbsp;Paris Charilaou ,&nbsp;Luisa Recinos ,&nbsp;Mehak Bassi ,&nbsp;Arkady Broder ,&nbsp;Kevan Salimian ,&nbsp;Mouen A. Khashab ,&nbsp;Saowanee Ngamruengphong","doi":"10.1016/j.tige.2023.01.003","DOIUrl":"https://doi.org/10.1016/j.tige.2023.01.003","url":null,"abstract":"<div><h3>Background and Aims</h3><p><span><span>Little is known about the outcomes of endoscopic resection<span> (ER) for patients with colorectal adenomas (CRAs) with high-grade </span></span>dysplasia (HGD) or intramucosal cancer (IMCA). This study aimed to estimate the rate of local/malignant recurrence, identify the </span>predictive factors<span> for local recurrence (LR), and evaluate the treatment outcomes of recurrence after ER for HGD/IMCA.</span></p></div><div><h3>Methods</h3><p>A retrospective review was performed to identify patients who underwent ER for HGD/IMCA in 2 academic medical centers. Risk factors for LR were determined by Cox regression analysis.</p></div><div><h3>Results</h3><p><span>Overall, 188 lesions with HGD/IMCA were included; 61 lesions were removed by en-bloc ER (e-ER), whereas 127 lesions were removed in a piecemeal ER (p-ER). The mean lesion size was 20.3 mm. Of the 125 patients who underwent follow-up, local adenoma recurrence occurred in 31 (23%), and malignant recurrence occurred in 2 (1.6%) patients at a median follow-up of 16 months. HGD/IMCA ≥ 4 cm removed by p-ER have the greatest hazard ratio (HR = 21.5; 95% CI 2.5-180.5; </span><em>P</em> = 0.005) for LR, compared with the HGD/IMCA &lt; 4 cm removed by e-ER. Surgery was performed in 3.2% of patients after a complete ER, all after p-ER. Of all patients who had LR, 22.6% (7/31 patients) had recurrent adenomas despite repeat ER attempts after a mean of 1.9 ± 0.79 procedures from the index ER.</p></div><div><h3>Conclusion</h3><p>Our study demonstrates a high rate of LR (23%) after ER of CRAs with HGD/IMCA with a rate of malignant recurrence of 1.6%, especially after p-ER. Thus, e-ER should be preferred for these lesions whenever technically feasible.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49750513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mucosal Impedance Spectroscopy for Objective Real-time Assessment of Mucosal Health","authors":"Priyanka Arora ,&nbsp;Jaspreet Singh ,&nbsp;Anuraag Jena ,&nbsp;Surinder Kumar ,&nbsp;Viren Sardana ,&nbsp;Siddhartha Sarkar ,&nbsp;Lileswar Kaman ,&nbsp;Arunanshu Behera ,&nbsp;Divya Dahiya ,&nbsp;Ritambhra Nada ,&nbsp;Cherring Tandup ,&nbsp;H.S. Jatana ,&nbsp;Usha Dutta","doi":"10.1016/j.tige.2023.03.007","DOIUrl":"https://doi.org/10.1016/j.tige.2023.03.007","url":null,"abstract":"<div><h3>Background and Aims</h3><p>There is a need for a real-time objective tool to assess the mucosal health of the gastrointestinal (GI) tract during endoscopy<span>. Our aim was to develop, design, and validate a low-cost mucosal impedance (MI) device and determine its role in differentiating diseased mucosa from normal mucosa.</span></p></div><div><h3>Methods</h3><p>A biocompatible catheter was designed and developed after multiple iterations. It was validated with a commercially available catheter and histopathological analysis in a blinded manner. Patients undergoing resection of the GI tract were recruited after consent, and the resected specimens were analyzed ex vivo for MI within 10 minutes of resection. An average of 3 MI readings of the visually diseased segment and adjacent normal segment were analyzed. MI values of diseased and non-diseased mucosa were compared.</p></div><div><h3>Results</h3><p>The in-house catheter was validated with a commercially available impedance measuring device. It showed a high degree of positive correlation (rho = 0.616; <em>P</em><span> &lt; 0.001). Two hundred and thirty-two patients (age 46 ± 15 years; 68% females) (180 inflammatory and 52 malignant pathology) who were undergoing abdominal surgery were enrolled. The median impedance value of diseased segments was significantly lower than that of the adjacent normal segments of gut in 130 paired samples [1832(727)Ω vs 2604(1295)Ω; </span><em>P</em> &lt; 0.001]. The MI value of segments containing malignant tissue (n = 50) and inflamed tissue (n = 80) was significantly lower than the MI value of adjacent normal segments of the GI tract [1880(977)Ω vs 2583(1431)Ω; <em>P</em> &lt; 0.001 and 1787(557)Ω vs 2515(1244)Ω; <em>P</em> &lt; 0.001, respectively]. There was a 24% reduction in visually diseased segments [median reduction 712(661)Ω] from adjacent normal segments. A biocompatible endoscopic catheter (3-mm diameter) has been developed and tested in 3 patients and was found to differentiate diseased from normal mucosa.</p></div><div><h3>Conclusion</h3><p>Impedance spectroscopy is an effective real-time, simple, objective tool to differentiate diseased gut mucosa from healthy mucosa.</p></div>","PeriodicalId":36169,"journal":{"name":"Techniques and Innovations in Gastrointestinal Endoscopy","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49749835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}