European Journal of Hybrid Imaging最新文献

{"title":"Bone scintigraphy outperformed anatomic images in frostbite injuries: a case report.","authors":"Brunela Ronchi,&nbsp;Gustavo Agustin Peña,&nbsp;Albertti Carla","doi":"10.1186/s41824-022-00146-1","DOIUrl":"https://doi.org/10.1186/s41824-022-00146-1","url":null,"abstract":"<p><p>Frostbite is a localized cold thermal injury, as a result of tissue exposure to temperatures below freezing point for a prolonged period of time. The spectrum of injury is broad; thus, frostbite injuries may have deleterious effects with the possibility of losing part or whole extremities. We aim to present the case of a 38-year-old male patient evaluated with multiphase technetium-99m-methylene diphosphonate bone scintigraphy. This methodology may accelerate clinical management of frostbite injuries because it provides precise clinical-imaging correlation by determining the extent of injury and can accurately predict the level of amputation if required.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"25"},"PeriodicalIF":1.7,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40674512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attenuation correction for PET/MRI to measure tracer activity surrounding total knee arthroplasty.","authors":"Caleigh E Bourdon,&nbsp;Zachary J Koudys,&nbsp;Brent A Lanting,&nbsp;C Thomas Appleton,&nbsp;Jonathan D Thiessen,&nbsp;Matthew G Teeter","doi":"10.1186/s41824-022-00152-3","DOIUrl":"https://doi.org/10.1186/s41824-022-00152-3","url":null,"abstract":"<p><strong>Background: </strong>Positron emission tomography (PET) in combination with magnetic resonance imaging (MRI) could allow inflammatory complications near total knee arthroplasty (TKA) to be studied early in their development. However, attenuation of the PET signal by the metal TKA implants imparts substantial error into measurements of tracer activity, and conventional MR-based attenuation correction (AC) methods have large signal voids in the vicinity of metal implants.</p><p><strong>Purpose: </strong>To evaluate a segmentation-based AC approach to measure tracer uptake from PET/MRI scans near TKA implants.</p><p><strong>Methods: </strong>A TKA implant (Triathlon, Stryker, Mahwah, USA) was implanted into a cadaver. Four vials were filled with [¹⁸F]fluorodeoxyglucose with known activity concentration (4.68 MBq total, 0.76 MBq/mL) and inserted into the knee. Images of the knee were acquired using a 3T PET/MRI system (Biograph mMR, Siemens Healthcare, Erlangen, Germany). Models of the implant components were registered to the MR data using rigid-body transformations and the other tissue classes were manually segmented. These segments were used to create the segmentation-based map and complete the AC. Percentage error of the resulting measured activities was calculated by comparing the measured and known amounts of activity in each vial.</p><p><strong>Results: </strong>The original AC resulted in a percentage error of 64.1% from the known total activity. Errors in the individual vial activities ranged from 40.2 to 82.7%. Using the new segmentation-based AC, the percentage error of the total activity decreased to 3.55%. Errors in the individual vials were less than 15%.</p><p><strong>Conclusions: </strong>The segmentation-based AC technique dramatically reduced the error in activity measurements that result from PET signal attenuation by the metal TKA implant. This approach may be useful to enhance the reliability of PET/MRI measurements for numerous applications.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"31"},"PeriodicalIF":1.7,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40446722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET/MR: primary inferior vena cava leiomyosarcoma.","authors":"Brunela Ronchi,&nbsp;Gustavo Agustin Peña,&nbsp;Carlos Sacchi","doi":"10.1186/s41824-022-00144-3","DOIUrl":"https://doi.org/10.1186/s41824-022-00144-3","url":null,"abstract":"<p><p>Positron emission tomography (PET) combined with a magnetic resonance (MR) scanner (PET/MR) with 18F-fluorodeoxyglucose (FDG) tracer is being used in quite a few nuclear medicine centers. The aim of this study is to illustrate two uncommon cases of primary inferior vena cava leiomyosarcoma which were formerly evaluated with anatomical images such as computed tomography and ultrasound. These techniques were inferior in the definition of the tumor and its characteristics. F-18 FDG PET/MR was essential and provided all the necessary information: its origin, local extension, anatomo-metabolic behavior, form of presentation, and distant metastasis in one single diagnostic technique. PET/MR accurately contributed to the diagnosis in a shortened period of time and, therefore, in the prognosis of this disease with greater benefits.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"24"},"PeriodicalIF":1.7,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9622966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40439615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reproducibility of lung cancer radiomics features extracted from data-driven respiratory gating and free-breathing flow imaging in [¹⁸F]-FDG PET/CT.","authors":"Daphné Faist, Mario Jreige, Valentin Oreiller, Marie Nicod Lalonde, Niklaus Schaefer, Adrien Depeursinge, John O Prior","doi":"10.1186/s41824-022-00153-2","DOIUrl":"10.1186/s41824-022-00153-2","url":null,"abstract":"<p><strong>Background: </strong>Quality and reproducibility of radiomics studies are essential requirements for the standardisation of radiomics models. As recent data-driven respiratory gating (DDG) [¹⁸F]-FDG has shown superior diagnostic performance in lung cancer, we evaluated the impact of DDG on the reproducibility of radiomics features derived from [¹⁸F]-FDG PET/CT in comparison to free-breathing flow (FB) imaging.</p><p><strong>Methods: </strong>Twenty four lung nodules from 20 patients were delineated. Radiomics features were derived on FB flow PET/CT and on the corresponding DDG reconstruction using the QuantImage v2 platform. Lin's concordance factor (C_b) and the mean difference percentage (DIFF%) were calculated for each radiomics feature using the delineated nodules which were also classified by anatomical localisation and volume. Non-reproducible radiomics features were defined as having a bias correction factor C_b  < 0.8 and/or a mean difference percentage DIFF% > 10.</p><p><strong>Results: </strong>In total 141 features were computed on each concordance analysis, 10 of which were non-reproducible on all pulmonary lesions. Those were first-order features from Laplacian of Gaussian (LoG)-filtered images (sigma = 1 mm): Energy, Kurtosis, Minimum, Range, Root Mean Squared, Skewness and Variance; Texture features from Gray Level Cooccurence Matrix (GLCM): Cluster Prominence and Difference Variance; First-order Standardised Uptake Value (SUV) feature: Kurtosis. Pulmonary lesions located in the superior lobes had only stable radiomics features, the ones from the lower parts had 25 non-reproducible radiomics features. Pulmonary lesions with a greater size (defined as long axis length > median) showed a higher reproducibility (9 non-reproducible features) than smaller ones (20 non-reproducible features).</p><p><strong>Conclusion: </strong>Calculated on all pulmonary lesions, 131 out of 141 radiomics features can be used interchangeably between DDG and FB PET/CT acquisitions. Radiomics features derived from pulmonary lesions located inferior to the superior lobes are subject to greater variability as well as pulmonary lesions of smaller size.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"33"},"PeriodicalIF":1.7,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40653849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrotizing granulomatous inflammation mimicking skeletal metastasis: a possible differential diagnosis.","authors":"Deepanksha Datta,&nbsp;T Ravichandran,&nbsp;Rajesh Kumar,&nbsp;Rashim Sharma,&nbsp;Deepak Vedant","doi":"10.1186/s41824-022-00151-4","DOIUrl":"https://doi.org/10.1186/s41824-022-00151-4","url":null,"abstract":"<p><p>Tuberculosis is an endemic disease in India for decades, and its coexistence in the patients with malignancy cannot be ignored. The non-specific uptake of 2-deoxy-2-[fluorine-18] fluoro-D-glucose in active infection and malignancy can affect the diagnosis and management of patients. However, characteristic anatomical features of the lesion aid not only in its localization but also in diagnosis. We share an interesting case of necrotizing granulomatous inflammation of dorsal spine mimicking skeletal metastases in a treated case of carcinoma cervix.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"30"},"PeriodicalIF":1.7,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9613828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40429083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncommon disseminated muscular metastasis from suspected lung adenocarcinoma in a 18F-FDG PET/CT study.","authors":"S Pacella","doi":"10.1186/s41824-022-00143-4","DOIUrl":"https://doi.org/10.1186/s41824-022-00143-4","url":null,"abstract":"<p><p>Skeletal muscle metastasis from lung cancer is a rare phenomenon. In this case report, FDG PET/CT imaging detected unexpected metastatic spread in skeletal muscles from lung cancer.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"23"},"PeriodicalIF":1.7,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40565288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations induced by body weight and background lesion normalization in standardized uptake value estimated by F18-FDG PET/CT.","authors":"Eman M Badawe,&nbsp;Hesham Abdel Gawad,&nbsp;Mohamed S El-Nagdy,&nbsp;Magdy M Khalil","doi":"10.1186/s41824-022-00142-5","DOIUrl":"https://doi.org/10.1186/s41824-022-00142-5","url":null,"abstract":"<p><strong>Aim: </strong>This work aims to study the impact of different SUV variants in terms of mean and maximum measures as well as various normalization methods with respect to body weight, body mass index, body surface area, and lean body mass in patients with lymphoma.</p><p><strong>Methods: </strong>Sixty-nine patients (34 male-35 female) were retrospectively selected. All patients had undergone F18-FDG PET/CT using the standard imaging protocol. In the first part of this study, SUVmean and SUVmax of patients' lesions and three background sites including liver, aorta, and muscle were determined. Then, the normalization of lesion SUV to body weight and body background sites was performed. The ratio of lesion SUVmax to body background sites (muscle, aorta, and liver) SUVmax was determined in addition to the ratio of lesion SUVmean to body background sites SUVmean. The second part of the study included the calculations of the body mass index (BMI), body surface area (BSA), and lean body mass (LBM). The normalization of lesion, liver, aorta, and muscle SUV to BMI, BSA, and LBM was calculated and compared to each other.</p><p><strong>Results: </strong>After performing the appropriate statistical calculations, the results showed that there is a significant difference in SUV measurements between the three background sites. Lesions normalized to the liver were significantly lower than those normalized to aorta and muscle and the results also showed a higher magnitude of lesions normalized to muscle in comparison to the aorta. The SUVmax and SUVmean normalized to different body weight indices showed the lowest variation with BSA and BMI while being increasingly higher with lean body mass using the two methods James and Janmahasatian, respectively, and then highest with body weight.</p><p><strong>Conclusion: </strong>The SUVmax and SUVmean showed lower variance in comparison to other background regions. Less variation was also remarkable in SUVmean normalized to BSA and Janma lean mass and also when SUVmax is normalized to James lean body mass. The SUVmax normalized to lean (i.e., James) as well as SUVmean normalized to lean (i.e., Janma) and BSA showed a significant independence with body weight.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"22"},"PeriodicalIF":1.7,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33502157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-sectional evaluation of FGD-avid polyostotic fibrous dysplasia: MRI, CT and PET/MRI findings.","authors":"Chiara Pozzessere,&nbsp;Francesco Cicone,&nbsp;Paolo Barberio,&nbsp;Annalisa Papa,&nbsp;Giuseppe Coppolino,&nbsp;Roberto Biagini,&nbsp;Giuseppe Lucio Cascini","doi":"10.1186/s41824-022-00139-0","DOIUrl":"https://doi.org/10.1186/s41824-022-00139-0","url":null,"abstract":"<p><p>A 42-year-old male with left hip pain was diagnosed of several right femoral and tibial bone tumours. All lesions were osteolytic with sclerotic margins. The symptomatic lesion in the proximal femur also showed bone expansion and focal cortical thinning. Whole-body [¹⁸F]-fluorodeoxyglucose (FDG) PET/CT and segmental PET/MRI of the left hip and femur were performed for metabolic characterization of the lesions and for biopsy guidance. The lesions showed a heterogenous degree of FDG uptake corresponding to different metabolic stages of the disease. A biopsy of the tumour portion showing the highest FDG uptake revealed a fibrous dysplasia (FD). In conclusion, although generally affecting paediatric and adolescent subjects, polyostotic FD may be detected in the adulthood. Despite the benign nature of the disease, increased glucose metabolism can be seen in some lesions. Hybrid imaging combining morphological and functional information may help guide biopsy and better define the treatment strategy.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"19"},"PeriodicalIF":1.7,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9527265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40386467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retention index of FDG-PET/CT SUVmax of the primary tumor in non-small cell lung cancer as a predictor of lymph node metastasis: a retrospective study.","authors":"Toshinari Ema,&nbsp;Hideaki Kojima,&nbsp;Shinji Mizuno,&nbsp;Tatsuo Hirai,&nbsp;Mikako Oka,&nbsp;Hiroshi Neyatani,&nbsp;Kazuhito Funai,&nbsp;Norihiko Shiiya","doi":"10.1186/s41824-022-00141-6","DOIUrl":"https://doi.org/10.1186/s41824-022-00141-6","url":null,"abstract":"<p><strong>Background: </strong>Accurate staging of non-small cell lung cancer is key in treatment planning and prediction of prognosis. We investigated the correlation between the maximum standardized uptake value (SUVmax) retention index (RI) of the primary tumor and lymph node metastasis in non-small cell lung carcinoma. We also evaluated the tendencies according to the histological types.</p><p><strong>Methods: </strong>We retrospectively evaluated 218 non-small cell lung cancer (NSCLC) tumors from 217 patients who underwent preoperative fluorodeoxyglucose-positron emission tomography/computed tomography (PET/CT) followed by lung surgery and lymph node resection between July 2015 and August 2020. All primary tumors were calculated as the SUVmax at 50 min (SUVmax_early [SUVmax_e]) and 120 min (SUVmax_delayed [SUVmax_d]), and RI. The clinicopathological factors of interest were compared based on lymph node metastasis status and NSCLC histopathological subtype.</p><p><strong>Results: </strong>The median SUVmax_e and SUVmax_d of the primary tumors were 3.3 and 4.2, respectively, and the median RI was 0.25. The RI was significantly higher in the pN(+) (n = 44) group (0.30) compared to the pN0 (n = 174) group (0.24) (p = 0.01). In patients with adenocarcinoma (n = 145), the RI was also significantly higher in the pN(+) (n = 29) group (0.29) compared to the pN0 (n = 116) group (0.16) (p < 0.01). A high RI of the primary tumor was an independent risk factor for lymph node metastasis, particularly in patients with adenocarcinoma (odds ratio: 12.30, p < 0.05).</p><p><strong>Conclusions: </strong>The RI of primary NSCLC tumors can help predict lymph node metastases, particularly in patients with adenocarcinoma.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"21"},"PeriodicalIF":1.7,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40376367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foreign body-type giant cell reaction with extensive granulation tissue and intense inflammation after chemotherapy mimicking residual lymphoma on FDG PET.","authors":"Sakib Kazi,&nbsp;Stavros Raptis,&nbsp;Farzad Abbaspour,&nbsp;Wanzhen Zeng","doi":"10.1186/s41824-022-00137-2","DOIUrl":"https://doi.org/10.1186/s41824-022-00137-2","url":null,"abstract":"<p><p>Foreign body-type giant cell reaction is typically a biological and immunological reaction to the presence of foreign bodies such as catheters, parasites or biomaterials with a collection of fused macrophages (giant cell). We reported an unusual case of [¹⁸F]FDG PET findings in diffuse large B cell lymphoma in the urinary bladder following incomplete resection and chemotherapy. As the restaging [¹⁸F]FDG PET showed intense [¹⁸F]FDG uptake in the urinary bladder at the resection site concerning for recurrence, the lesion was subsequently resected and histopathology showed extensive granulation tissue with foreign body-type giant cell reaction with no suspected foreign bodies or neoplasia.</p>","PeriodicalId":36160,"journal":{"name":"European Journal of Hybrid Imaging","volume":" ","pages":"18"},"PeriodicalIF":1.7,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40357100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}