New Frontiers in Medicine and Medical Research Vol. 1最新文献

{"title":"A Brief Study on Rectus Sheath Hematoma","authors":"S. Dube","doi":"10.9734/bpi/nfmmr/v1/3029f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/3029f","url":null,"abstract":"Rectus sheath hematoma (RSH) is rare but potentially life threatening complication following any surgical procedure. The non specific nature of entity, lower incidence of disorder and acute presentation may possess difficulty in timely recognizing the condition. It can present as a relatively mild problem to life threatening condition. Relatively rare in incidence deserves a special place of this condition, so that every young doctor is aware about the condition. This is an attempt to raise the awareness about this condition as fast and timely intervention may prove to be life saving step.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114198554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrauterine Fetal Demise - A Tragic Event: An Approach to its Epidemiology, Causes and Methods of Induction","authors":"A. Dave, Ranjana Patidar, S. Goyal, A. Dave","doi":"10.9734/bpi/nfmmr/v1/3005f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/3005f","url":null,"abstract":"Background:  Fetal death is a tragedy that causes parents and caregivers great grief. The majority of newborns are born healthy, but occasionally something goes wrong and a baby dies while still in the womb. The goal of this study was to learn more about the incidence, epidemiology, and aetiology of intrauterine foetal death. In addition, the efficacy of misoprostol and dinoprostone as inducing agents in these situations should be investigated. \u0000The demographic and clinical characteristics of the patients were noted. Induction delivery interval of inducing agents was compared. \u0000Results: At our centre, the rate of IUFD was found to be 50 per 1000 deliveries. The primary causes were unbooked cases, primigravidas, and preterm with abruption, which had a significant frequency in low socioeconomic strata. In these circumstances, misoprostol was proven to be more successful at terminating the pregnancy. Misoprostol had a 9.64-hour induction delivery interval, while dinoprostone had a 12.63-hour induction delivery interval.   \u0000Conclusions: Many causes of intrauterine deaths are preventable, such as abruption hypertensive disorders, which can be avoided with proper antenatal care. Socio-demographic factors such as low socioeconomic status, teenage pregnancy, poor nutrition, and a lack of health education should be considered as predisposing factors for prenatal deaths. Misoprostol is less expensive and has a shorter induction delivery interval; it can be used safely in IUFD instances.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"194 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127561084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An in vivo Study of the Feasibility of Different Methods after Debonding of Orthodontic Brackets","authors":"Juhi Yadav, Madhulika Yadav, Danish U. Z. Khan, N. Grover","doi":"10.9734/bpi/nfmmr/v1/3255f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/3255f","url":null,"abstract":"Aim: The objective of this study is to evaluate and compare the levels of discomfort thorough Visual analogue scale (VAS) experienced during debonding using three different methods, as well as the adhesive remnant index (ARI) scores. \u0000Materials and Methods: 50 female patients from a single clinic were studied in the study, with a mean age of 24 years and 5 months. Lift-off debonding instrument, straight cutter and Howe plier were the three methods used to study during debonding of orthodontic appliances. Discomfort levels were measured using a visual analogue scale at the end of debonding in each quadrant (VAS). ARI was used to investigate the remaining adhesive on the enamel surface. \u0000Results: The Straight cutter technique resulted in much greater pain scores. The Lift off debonding instrument method was the least discomfort causing method .The three approaches utilised by ARI yielded significantly varied findings. \u0000Conclusion: When the Lift off debonding instrument method was utilised, the patients showed the least amount of discomfort.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125138255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fiducial Marker-Guided Radiotherapy Practices in Prostate Cancer Treatment","authors":"C. şen","doi":"10.9734/bpi/nfmmr/v1/3297f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/3297f","url":null,"abstract":"The fiducial marker application technique in prostate radiotherapy is an effective accompanying radiotherapy method in reducing acute and chronic side effects of radiotherapy, safely administering higher doses and contributing to local and overall survival without discomforting the patient. It is minimally invasive and safe. It can be easily tolerated by patients. It is an important technique that should be performed in cooperation with Radiation Oncology and Urology / Radiology Clinics, which have the necessary infrastructure. This paper aimed to provide general information about the types and application techniques of fiducial markers.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"214 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131511652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Portal Vein Diameter and Velocity Using Ultrasound","authors":"M. Ahmed","doi":"10.9734/bpi/nfmmr/v1/11207d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/11207d","url":null,"abstract":"This study was conducted to establish standards of normal portal vein diameter and portal venous velocity via ultrasound and can be helpful in early detection of portal hypertension as well as to have indigenous index for healthy Sudanese correlate with body characteristic based on age, gender, weight, height and abdominal circumference (AC) .Importance of the study to help in diagnosis portal hypertension in early stage to avoid the complication. As well as to reduce the cost and time of examination. The data was collected, analyzed by using Statistical Packaged for Social Studies (SPSS). Duplex ultrasound examinations were performed in Khartoum Bahri Hospital, Khartoum State during the period )from may 2015 to December 2015(, on 100 patients (49 male and 51 female ) with normal abdominal scan (hypertension, DM and patient who has chronic liver disease are exclusion criteria).The analysis of the results found that the most age group ranged between (20 to 29) years forming (33%) of the sample volume, the most body weight ranged from (60 to 69) Kg forming (38%),the hight of the body from (160 to 169) cm in (39%),the abdominal circumference between (70-79)cm in (30%)of patients. In result we found the portal vein diameter increase with age and weight but the values are similar in male and female. No significant correlation was detected between portal vein diameter, height and abdominal circumference (AC). Highly significant correlation was detected between portal vein diameter and portal vein velocity of patient (increase velocity with decreasing diameter), these was expected and goes with previous study. The study also found that there was significant correlation between Sudanese portal vain diameter and velocity and international standard. \u0000The study recommended further study to correlate normal portal vein diameter and velocity with liver size.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132221474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for Mitochondrial A1555G Mutation among Assortative Mating Hearing Impaired Families in South India: Some Vital Insights","authors":"Pavithra Amritkumar, C. Srisailapathy","doi":"10.9734/bpi/nfmmr/v1/3292f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/3292f","url":null,"abstract":"Unravelling the mechanism of non-syndromic hearing loss (NSHL) through genetic studies have till date been perplexed by several factors such as genetic heterogeneity, multiple phenotypes, consanguinity and marriages between hearing impaired persons. A1555G mutation in the MT-RNR1 gene has been identified to be one of the most common mitochondrial mutations in several populations and it has been associated with both NSHL as well as aminoglycoside induced ototoxicity. \u0000Objective: A detailed study was carried out to screen for the prevalence of mitochondrial A1555G mutation among assortatively mating hearing impaired families from South India. \u0000Subjects and Methods: Owing to the variable phenotypic expressivity of this mutation, all the available family members (hearing and hearing impaired) in 106 assortatively mating hearing impaired families, (60 DXD and 46 DXN mating type), comprising of 616 members in all (277 HI individuals and 339 normal hearing family members) were screened for the presence of A1555G mutation by PCR-RFLP method. Mitochondrial A1555G mutation in the 12SrRNA gene was screened by PCR-RFLP method and confirmed by direct sequencing of entire 12SrRNA gene using suitable primers. Additionally, all the individuals carrying the A1555G mutation, along with their family members were screened for GJB2 gene mutations by direct sequencing method. \u0000Results: On screening 616 members belonging to 106 assortatively mating families for A1555G mitochondrial DNA mutation, we found seven members in a family with variable phenotypes ranging from normal hearing to moderately severe hearing loss, having this mutation with clear matrilineal transmission. \u0000Conclusions: A1555G mutation in the 12SrRNA gene has been identified to be one of the most common mitochondrial mutations and it has been associated with both non-syndromic hearing loss as well as aminoglycoside induced ototoxicity. This is the first report from India on the prevalence of A1555G mutation in normal hearing individuals indicating the impending need to screen this common mitochondrial mutation on a large scale not only among the hearing impaired families but also in the normal hearing Indian population.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128954971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Association of Serum Uric Acid, Homocystine and Ferritin among Amyotrophic Lateral Sclerosis Patients in Bangladesh","authors":"Mohammad Raknuzzaman, Tasnim Jannaty, Md. Anis Ahmed, A. Shams, Md. Hasan Ali Masum, M. Rana","doi":"10.9734/bpi/nfmmr/v1/10846d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/10846d","url":null,"abstract":"Background: Amyotrophic lateral sclerosis (ALS) is a disease that involves the death of neurons that regulate voluntary muscles. It is also known as motor neuron disease (MND) or Lou Gehrig's illness.A link between serum uric acid, homocystine, and ferritin and amyotrophic lateral sclerosis may exist. \u0000However, we do not have adequate information on these topics. Objective: The main objective of this study was to evaluate the association of serum uric acid, homocystine and ferritin with amyotrophic lateral sclerosis. \u0000Materials and Methods: From January 2010 to December 2011, a case-control research was done in the department of neurology at Bangabandhu Sheikh Mujib Medical University in Dhaka, Bangladesh. After the study was completed, the 76 individuals were divided into two equal groups, each with 38 participants. There were 38 ALS patients in group I (case group) and 38 healthy adults in group II (control group). Data was collected using pre-designed questioners, which were then processed and analysed with SPSS version 11.5. \u0000Results: In this study approximately 11% of patients in case group and 5.3% participants in control group (Each of 15.8%) were former smoker only. In case group the mean (±SD) uric acid level was 4.27±1.41 mg/dL whereas it was 4.27±1.41 mg/dL in control group and we found a significant correlation between both the groups (p value > 0.05). In analyzing the association of uric acid with gender of case group we found s significant correlation as the p value was less than 0.05. We found reading of serum uric acid lower in female. In this study, serum uric acid level is inversely correlated with duration of illness and positively correlated with ALS functional rating scale. \u0000Conclusion: Amyotrophic lateral sclerosis patients had lower serum UA levels than healthy individuals and it was significantly lower in female ALS-patients than that of male ALS-patients. Uric acid levels in case group were positively correlated with the ALSFRS-R (severity) and negatively associated with duration of illness. UA levels could be considered as a biomarker of disease progression in the early phase of ALS.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114928933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Migrations as a Public Health Issue","authors":"Obradovic Zarema","doi":"10.9734/bpi/nfmmr/v1/11359d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/11359d","url":null,"abstract":"Migrations are temporary or permanent changes of place of residence, and migrants are persons who temporarily or permanently leave their home or their country, depending on whether they are migrations inside or outside the country. The reasons for migration are different: economic, political, natural disasters and wars. About 3.6% of the world’s population lives outside their place of residence, and the number of migrants is constantly increasing, and it is estimated that in 2050 there will be 405 million migrants in the world. Migrations are the displacement of people, but also the mobility of cultures, health habits and epidemiological factors and risks, and contribute to the increase in the number of infectious and non-communicable diseases among migrants and the local population in the countries they pass through or continue to live in. \u0000The aim is to point out the importance of migration as a public health problem that affects migrants, but also the local population. \u0000Methods: Review of scientific literature and reports of relevant institutions on the impact of migration on the occurrence of the disease in population. \u0000Results: Migrants are all ages, except very old people, they are of both sexes, but there are more men who leave their country of birth for different reasons. A special problem are children who migrate unaccompanied by a parent or guardian. The occurrence of diseases in migrants is influenced by: personal characteristics of migrants, reasons for migration, ways of migration, the season in which migrations occur, hygienic and sanitary conditions in the areas through which migrants pass and conditions at the final destination. Economic migrations have the least impact on health because they happen according to plan, migrants travel with adequate transportation, have accommodation and work at their final destination. Unplanned migrations caused by wars, natural disasters, or some political reasons have a great negative impact on health. The health of these migrants is at great risk because they travel by unsafe means of transport, without documents, including health identification cards, cross the borders illegally and stay illegally in the countries of transit and the host country. This category of migrants does not have adequate accommodation, nor adequate access to health care, they are under constant stress which affects the onset of the disease. Migrants live in groups, so infectious diseases are easily spread among them, and they are also transmitted to the local population. Due to the inadequate approach to health care, the diagnosis of diseases, infectious and especially non-infectious, is made late in migrants, so treatment is often delayed. Linguistic and cultural barriers are a big problem for migrants in exercising their rights. \u0000Conclusion: Migration is a significant public health problem today and should be addressed in a systematic way with the involvement of whole community.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126925262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Pediatric Bacterial Meningitis Due to the Rare Isolate, Pseudomonas putida: A Case Report","authors":"Grishma V. Kulkarni","doi":"10.9734/bpi/nfmmr/v1/10912d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/10912d","url":null,"abstract":"Acute bacterial meningitis (ABM) is a medical emergency that necessitates prompt diagnosis and aggressive treatment. Despite the availability of newer, more effective antibiotics, ABM and its consequences continue to attack people in India, with fatality rates ranging from 16 to 32 percent. The purpose of this case report is to describe the rare isolation of Pseudomonas putida from a sample of cerebrospinal fluid.Apart from that, the author underlines the necessity of correctly identifying the organism and thus selecting the most appropriate antibiotic from the susceptibility profile in order to allow for early recovery and improve the patient's result and survival.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"2008 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125624132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Profile and Outcomes of Acute Kidney Injury Patients in an Intensive Care Unit in India: A Retrospective Study","authors":"V. Pillai, C. Verghese, C. Pais, V. Rai, M. Chakrapani","doi":"10.9734/bpi/nfmmr/v1/3071f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v1/3071f","url":null,"abstract":"Background: In developing countries, there is a scarcity of epidemiology and outcome data on acute kidney injury (AKI). The current single-site study aims to define the clinical profile of AKI in patients admitted to intensive care units at a tertiary care institution in Mangalore, India, by attempting to identify the presenting symptoms, etiologies, treatment methods, and disease prognosis. \u0000Methods: Between October 2001 and October 2003, 70 AKI patients with a serum creatinine level greater than 1.4 mg/dl and blood urea greater than 53 mg/dl were enrolled in this retrospective study at Wenlock district hospital, Mangalore, KMC hospital Attawar, Mangalore, and KMC hospital, Jyothi circle, Mangalore. \u0000Results: Amongst the enrolled patients, 45.7% of patients were in the 40-60 years age group, 49 males with no significant (p=0.412) gender difference. The most common presenting symptom was decreased micturition, which was present in 47.1 percent of patients, and the most common aetiology of AKI was sepsis, which was also associated with the highest (17.1 percent) mortality. The mortality rate for patients who had conservative treatment (n=52) was 42.8 percent, while the mortality rate for those who received hemodialysis (n=18) was 4.2 percent. The overall survival rate in the study was 52.9%. \u0000Conclusions: The epidemiological data in this study is consistent with prior studies in India, with hemodialysis appearing to have better disease outcomes than conservative therapy.","PeriodicalId":360142,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 1","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121285882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}