Acta medica (Hradec Kralove)最新文献_第9页

Association of XPC Polymorphisms with Cutaneous Malignant Melanoma Risk: Evidence from a Meta-Analysis. XPC 多态性与皮肤恶性黑色素瘤风险的关系：一项 Meta 分析的证据。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.27

Fatemeh Asadian, Seyed Mohammadreza Niktabar, Yaser Ghelmani, Shadi Kargar, Elahe Akbarian, Seyed Alireza Emarati, Jalal Sadeghizadeh-Yazdi, Hossein Neamatzadeh

{"title":"Association of XPC Polymorphisms with Cutaneous Malignant Melanoma Risk: Evidence from a Meta-Analysis.","authors":"Fatemeh Asadian, Seyed Mohammadreza Niktabar, Yaser Ghelmani, Shadi Kargar, Elahe Akbarian, Seyed Alireza Emarati, Jalal Sadeghizadeh-Yazdi, Hossein Neamatzadeh","doi":"10.14712/18059694.2020.27","DOIUrl":"10.14712/18059694.2020.27","url":null,"abstract":"Background: A number of studies have reported that the xeroderma pigmentosum complementation group C (XPC) polymorphisms are associated with cutaneous malignant melanoma (CMM) susceptibility. But the results of those studies were inconsistent. Here, we performed a study to obtain a more conclusive result on the association of XPC polymorphisms with risk of CMM.Methods: The XPC Lys939Gln and Ala499Val polymorphisms were genotyped in 150 CMM cases and 150 controls by PCR-RFLP assay. Subsequently, all published relevant studies were identified through a comprehensive literature search in PubMed, Web of Science, and CNKI databases. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to estimate the strength of correlation.Results: There was no significant association between XPC Lys939Gln and Ala499Val polymorphisms and CMM risk in our population. A total of 15 case-control studies including ten studies with 5,990 cases and 7,697 controls on XPC Lys939Gln and five studies with 3,139 cases and 3,721 controls on XPC Ala499Val polymorphism were selected. Pooled data revealed that XPC Lys939Gln (C vs. A: OR = 1.108, 95% CI 1.008- 1.217; P = 0.033) and Ala499Val (C vs. A: OR = 0.918, 95% CI 0.850-0.992; p = 0.031; CC+CA vs. AA: OR = 0.904, 95% CI 0.819-0.997; p = 0.043) polymorphisms were significantly associated with an increased risk of CMM. Moreover, stratified analyses by ethnicity revealed that the XPC Ala499Val and Lys939Gln polymorphisms were significantly associated with risk of CMM in Caucasians and mixed populations, respectively.Conclusions: This meta-analysis result suggested that XPC Lys939Gln and Ala499Val polymorphisms were significantly associated with risk of CMM.","PeriodicalId":35758,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"63 3","pages":"101-112"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38543327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Acute Compartment Syndrome. 急性筋膜室综合征。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.26

Jana Cepková, Leoš Ungermann, Edvard Ehler

引用次数: 4

Hydrocele in Pediatric Population. 儿科人群的鞘膜积液。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.17

Ioannis Patoulias, Efstathios Koutsogiannis, Ioannis Panopoulos, Panagiota Michou, Thomas Feidantsis, Dimitrios Patoulias

引用次数: 8

Oral Manifestations of Nutritional Deficiencies: Single Centre Analysis. 营养缺乏的口腔表现:单中心分析。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.25

Vladimíra Radochová, Radovan Slezák, Jakub Radocha

{"title":"Oral Manifestations of Nutritional Deficiencies: Single Centre Analysis.","authors":"Vladimíra Radochová, Radovan Slezák, Jakub Radocha","doi":"10.14712/18059694.2020.25","DOIUrl":"https://doi.org/10.14712/18059694.2020.25","url":null,"abstract":"INTRODUCTION\u0000Oral manifestations of deficiency of iron, vitamin B12 and folic acid are thought to be common. Prevalence of these deficiencies among patients with compatible symptoms is not well known. The goal of this study was to summarize evidence from a dental practice of iron, vitamin B12 and folic acid deficiency in patients presenting with compatible oral manifestations.\u0000\u0000\u0000METHODS\u0000250 patients who presented with burning mouth syndrome, angular cheilitis, recurrent aphthous stomatitis, papillar atrophy of the tongue dorsum or mucosal erythema were identified. Patients underwent clinical examination, and the blood samples were taken.\u0000\u0000\u0000RESULTS\u0000250 patients (208 females; 42 males, mean age 44.1 years) with at least one corresponding symptom or sign were identified. The nutritional deficiency of one or more nutrients was found in 119 patients (47.6%). Seven times more females than males were noted to have one type of deficiency (104 females, 15 males). Iron deficiency as defined was diagnosed in 62 patients (24.8%), vitamin B12 or folic acid deficiency in 44 patients (17.6%) and both deficiencies (iron + vitamin B12/folic acid) in 13 patients (5.2%). The only predictive factor was gender and only for iron deficiency. The presence of more than one deficiency was noted in 10 patients (4.9%).\u0000\u0000\u0000CONCLUSION\u0000The most commonly observed deficiency in dental practice over the course of 11 years was an iron deficiency in the female population. Age, diet and reported co-morbidities did not show statistically significant predictable value in recognizing these deficiencies.","PeriodicalId":35758,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"63 3","pages":"95-100"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38543326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Duodenal Pressure Necrosis in a Child Caused by a Migrated Percutaneous Endoscopic Gastrostomy. 儿童经皮内视镜胃造口术所致十二指肠压力性坏死1例。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.21

Jan Melek, Markéta Štanclová, Radek Štichhauer, Pavel Rozsíval, Jan Kopřiva, Jana Dědková, Eva Terifajova, Eva Šedivá, Petr Dědek, Sylva Skálová, Jan Bureš

{"title":"Duodenal Pressure Necrosis in a Child Caused by a Migrated Percutaneous Endoscopic Gastrostomy.","authors":"Jan Melek, Markéta Štanclová, Radek Štichhauer, Pavel Rozsíval, Jan Kopřiva, Jana Dědková, Eva Terifajova, Eva Šedivá, Petr Dědek, Sylva Skálová, Jan Bureš","doi":"10.14712/18059694.2020.21","DOIUrl":"https://doi.org/10.14712/18059694.2020.21","url":null,"abstract":"A two-year-old girl with two weeks of abdominal pain, vomiting, and food refusal, ten months after percutaneous endoscopic gastrostomy insertion because of inadequate peroral intake, was admitted to a tertiary centre hospital. On admission, the extracorporeal part of the gastrostomy was much shortened. X-ray examination revealed migration of the end of the gastrostomy tube with a left-shifted course of the tube through the duodenum. Gastroscopy and subsequently laparotomy were performed. A longitudinal pressure necrosis was identified under the tube, with two perforations in the duodenojejunal region. Ten centimeters of that duodenojejunal region were resected, and end-to-end anastomosis was made. The migration of the gastrostomy was probably caused by insufficient care by the parents. Pathophysiologically, the tube caused the pressure necrosis in the duodenojejunal area; this was supported by histology. This is a hitherto undescribed complication of a percutaneous endoscopic gastrostomy, showing that migration of the gastrostomy to the deeper part of the small bowel can lead to pressure necrosis, a potentially life-threatening condition in children which cannot be treated without invasive procedures.","PeriodicalId":35758,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"63 2","pages":"79-81"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38252848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Candida Skull Base Osteomyelitis: a Case Report and Literature Review. 念珠菌颅底骨髓炎1例报告及文献复习。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.22

Madhusudhan Krishnamoorthy, Nik Adilah Nik Othman, Nor Eyzawiah Binti Hassan, Shahrul Bin Hitam

引用次数: 3

Thyrotoxic Hypokalemic Periodic Paralysis Triggered by Dexamethasone Administration. 地塞米松引起的甲状腺毒性低钾血症性周期性麻痹。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.24

Waraporn Polamaung, Jaruwan Kongkit, Parichat Yimnoi, Patchaya Boonchaya-Anant, Thiti Snabboon

引用次数: 3

An Alternative Treatment for Vaginal Cuff Wart: a Case Report. 阴道袖口疣的另一种治疗方法:一例报告。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.15

Victoria Psomiadou, Christos Iavazzo, Athanasios Douligeris, Alexandros Fotiou, Anastasia Prodromidou, Nikolaos Blontzos, Evgenia Karavioti, George Vorgias

{"title":"An Alternative Treatment for Vaginal Cuff Wart: a Case Report.","authors":"Victoria Psomiadou, Christos Iavazzo, Athanasios Douligeris, Alexandros Fotiou, Anastasia Prodromidou, Nikolaos Blontzos, Evgenia Karavioti, George Vorgias","doi":"10.14712/18059694.2020.15","DOIUrl":"https://doi.org/10.14712/18059694.2020.15","url":null,"abstract":"Human papillomavirus (HPV) has been directly related to acuminate warts and cervical cancer, the second most common neoplasia among women. Given the lack of treatment against the virus itself, many medications have been utilised, mainly aiming in modifying the host's immunological response. We present the case of a 54 years old postmenopausal patient with a history of vaginal cuff wart and HPV persistence that we managed in our clinic for 6 months with a mix of curcumin, aloe vera, amla and other natural ingredients. As the patient was found to be intolerant to imiquimod (one of the most common conservative methods of treatment) we attempted the use of curcumin, which was applied to the area of the wart three times per week for 6 months. Both clinical and colposcopical improvement was noted in regular clinic visits with regression of the lesion. The outcome of this case encourages our view that curcumin should be considered as a significant treatment modality against HPV infection and acuminate warts.","PeriodicalId":35758,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"63 1","pages":"49-51"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37946997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Sensitization to Molecular Components in 104 Atopic Dermatitis Patients in Relation to Subgroups of Patients Suffering from Bronchial Asthma and Allergic Rhinitis. 104例特应性皮炎患者与支气管哮喘和变应性鼻炎亚组的分子成分致敏性

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.59

Radka Vaňková, Jarmila Čelakovská, Josef Bukač, Irena Krčmová, Jan Krejsek, Ctirad Andrýs

{"title":"Sensitization to Molecular Components in 104 Atopic Dermatitis Patients in Relation to Subgroups of Patients Suffering from Bronchial Asthma and Allergic Rhinitis.","authors":"Radka Vaňková, Jarmila Čelakovská, Josef Bukač, Irena Krčmová, Jan Krejsek, Ctirad Andrýs","doi":"10.14712/18059694.2020.59","DOIUrl":"https://doi.org/10.14712/18059694.2020.59","url":null,"abstract":"Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease. The progression from AD to bronchial asthma (AB) and allergic rhinitis (AR) is called atopic march. The aim of this study was to evaluate the difference in the sensitization to molecular components in patients suffering from AD in relation to subgroups of patients with AR and AB.Material and methods: The complete dermatological and allergological examinations were performed. Specific IgE antibodies against 112 molecular components were measured with the multiplex ImmnoCAP ISAC test.Results: Altogether 104 atopic dermatitis patients (50 men, 54 women) at the average age 40.1 years were examined. The sensitization to molecular components was confirmed in 93.3% of patients. The sensitization to components of mites, grasses, trees, animals, moulds, and shrimps was significantly more frequent in patients with severe form of AD and the sensitization to components of grasses, trees, and moulds was significantly higher in subgroup of patients with AB. In subgroup of patients suffering from AR the higher occurrence of pollen-derived and pollen-food derived PR-10 proteins, grasses, mites, and animals was observed also.Conclusions: We have confirmed the significant differences in the sensitization to molecular components in patients suffering from severe form of AD, and in subgroups of patients suffering from AB and AR. These molecular components may play the important role in the consecutive development of different allergy pathologies called atopic march.","PeriodicalId":35758,"journal":{"name":"Acta medica (Hradec Kralove)","volume":"63 4","pages":"164-175"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39092733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Robotic Management of Fibroids: Discussion of Use, Criteria and Advantages. 肌瘤的机器人治疗:使用、标准和优势的讨论。

Acta medica (Hradec Kralove) Pub Date : 2020-01-01 DOI: 10.14712/18059694.2020.18

Ioannis D Gkegkes, George Iatrakis, Paraskevi-Evangelia Iavazzo, Konstadia Bakalianou, Christos Iavazzo

引用次数: 2