Acta Gastroenterologica Latinoamericana最新文献_第4页

[Lactose Malabsorption and Intolerance]. [乳糖吸收不良和乳糖不耐受]。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-06-30 eCollection Date: 2025-04-01 DOI: 10.52787/agl.v55i2.495

Ana L Ordoñez-Vázquez, Abigail Fuentes-Montalvo, Enrique Coss-Adame

{"title":"[Lactose Malabsorption and Intolerance].","authors":"Ana L Ordoñez-Vázquez, Abigail Fuentes-Montalvo, Enrique Coss-Adame","doi":"10.52787/agl.v55i2.495","DOIUrl":"10.52787/agl.v55i2.495","url":null,"abstract":"Lactose malabsorption and lactose intolerance are common yet clinically distinct conditions. Lactose malabsorption refers to the passage of undigested lactose into the colon due to lactase deficiency, whereas lactose intolerance involves the onset of gastrointestinal symptoms following lactose ingestion in the presence of malabsorption. Alactasia is a rare congenital disorder characterized by complete absence of lactase activity. Primary hypolactasia is a physiological and genetically determined decline in lactase activity occurring in adulthood. Globally, the prevalence of lactose malabsorption affects up to two-thirds of the population, with particularly high rates in Latin America and Mexico. Diagnosis can be established through non-invasive methods such as the hydrogen breath test, genetic testing, the gaxilose test, and lactose tolerance testing, or through invasive procedures like enzymatic activity measurement in duodenal biopsies. Management should aim to control symptoms without compromising nutritional status and may include low-lactose diets, oral lactase enzyme supplementation, and the use of probiotics or prebiotics. Avoiding unnecessary dietary restrictions is essential to prevent nutritional deficiencies or the development of avoidant/restrictive food intake disorder. An individualized diagnostic and therapeutic approach improves both clinical outcomes and quality of life in affected patients.","PeriodicalId":35700,"journal":{"name":"Acta Gastroenterologica Latinoamericana","volume":"55 2","pages":"88-102"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Emerging Nutritional Interventions for Irritable Bowel Syndrome: Starch- and Sucrose-Reduced Diet and Mediterranean Diet]. [肠易激综合征的新兴营养干预：淀粉和蔗糖减少饮食和地中海饮食]。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-06-30 eCollection Date: 2025-04-01 DOI: 10.52787/agl.v55i2.504

Sara Noemí Schaab, María Cielo Gutiérrez

引用次数: 0

[Solid Pseudopapillary Neoplasm of the Pancreas: Diagnosis and Surgical Management in a Young Patient]. [胰腺实性假乳头状瘤：一例年轻患者的诊断和手术治疗]。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-06-30 eCollection Date: 2025-04-01 DOI: 10.52787/agl.v55i2.469

Elías Lessin García Alba, Magalí Chahdi Beltrame, Natalia Soledad Ruíz, Gabriel Cervantes, Marcelo Enrique Lenz Virreira, Francisco Juan Mattera, Emilio Gastón Quiñonez

{"title":"[Solid Pseudopapillary Neoplasm of the Pancreas: Diagnosis and Surgical Management in a Young Patient].","authors":"Elías Lessin García Alba, Magalí Chahdi Beltrame, Natalia Soledad Ruíz, Gabriel Cervantes, Marcelo Enrique Lenz Virreira, Francisco Juan Mattera, Emilio Gastón Quiñonez","doi":"10.52787/agl.v55i2.469","DOIUrl":"https://doi.org/10.52787/agl.v55i2.469","url":null,"abstract":"A solid pseudopapillary neoplasm of the pancreas is a rare tumor accounting for 1-2% of exocrine pancreatic neoplasms and around 5% of cystic pancreatic lesions in adults. It predominantly affects young women and is usually diagnosed incidentally due to its non-specific clinical presentation. Although its exact cause is unclear, it is believed to originate from pluripotent cells of the genital ridges. We report the case of a 26-year-old female patient with an asymptomatic epigastric mass. An magnetic resonance scan revealed a large, heterogeneous lesion in the head of the pancreas, with no evidence of vascular invasion or metastasis. A cephalic duodenopancreatectomy was performed, achieving tumour-free margins with no lymphovascular or perineural involvement. The patient had a favourable postoperative recovery, with no recurrence after three years of follow-up. These neoplasms are diagnosed based on imaging studies, and complete surgical resection is the treatment of choice. Despite their low malignant potential, factors such as tumour size, capsular invasion, and cellular atypia may influence prognosis. This case highlights the importance of treatment in specialized centers to optimize oncological outcomes.","PeriodicalId":35700,"journal":{"name":"Acta Gastroenterologica Latinoamericana","volume":"55 2","pages":"157-161"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13108682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Morbidity and Mortality after Subtotal versus Total Open Gastrectomy for Gastric Cancer with Curative Intent: Findings in a Historical Cohort from a Cancer Center]. [胃癌小全切开与全切开胃切除术后的发病率和死亡率：来自癌症中心的历史队列研究结果]。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-06-30 eCollection Date: 2025-04-01 DOI: 10.52787/agl.v55i2.498

Jesús Chang-Hermida, Fernando Miñán-Arana, Arantza Gabriela Carriel-Mendoza, Leonardo Aveiga-Cedeño, Miguel Puga-Tejada

{"title":"[Morbidity and Mortality after Subtotal versus Total Open Gastrectomy for Gastric Cancer with Curative Intent: Findings in a Historical Cohort from a Cancer Center].","authors":"Jesús Chang-Hermida, Fernando Miñán-Arana, Arantza Gabriela Carriel-Mendoza, Leonardo Aveiga-Cedeño, Miguel Puga-Tejada","doi":"10.52787/agl.v55i2.498","DOIUrl":"10.52787/agl.v55i2.498","url":null,"abstract":"Introduction: Data on morbidity and mortality after subtotal or total gastrectomy are scarce in developing countries, especially considering the epidemiological shift in gastric cancer (decrease in distal and increase in proximal tumors).Objective: To identify factors associated with morbidity and mortality in patients with gastric cancer undergoing curative-intent surgery at a cancer center in Ecuador.Materials and methods: Historical cohort study conducted at the National Oncology Institute \"Dr. Juan Tanca Marengo\" in Guayaquil (2019 - 2021). Only adenocarcinomas treated with curative intent were included. Outcomes were postoperative complications and mortality at 30, 90 days, and overall. Logistic regression was used to estimate factors associated with higher risk.Results: A total of 111 patients were included (87 subtotal, 24 total gastrectomy). At least one complication occurred in 15.4% (subtotal) and 17.9% (total). Thirty-day, 90-day, and overall mortality after subtotal gastrectomy were 1.1%, 2.3%, and 34.5%; after total gastrectomy, 0%, 4.2%, and 54.2%, respectively. Postoperative complications were significantly associated with Bormann III/IV tumors (OR 9.6; 95% CI 1.8 - 79.7; p = 0.0175) and longer hospital stay (OR 2.3; 95% CI 1.4 - 5.1; p <0.001). Mortality was associated with Bormann III/IV tumors (p = 0.0038) and gastro-duodenal leak (p = 0.0383).Conclusion: Ninety-day morbidity and mortality rates were lower than previously reported. Bormann III/IV tumors and postoperative gastro-duodenal leakage were associated with increased mortality.","PeriodicalId":35700,"journal":{"name":"Acta Gastroenterologica Latinoamericana","volume":"55 2","pages":"136-147"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Prognostic Factors and Survival in Patients Undergoing Surgery for Pancreatic Ductal Adenocarcinoma: a MultiCenter Retrospective Analysis]. 胰腺导管腺癌手术患者的预后因素和生存率：一项多中心回顾性分析。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-06-30 eCollection Date: 2025-04-01 DOI: 10.52787/agl.v55i2.482

Sofía Gamboa Miño, Gustavo Kohan, Rodrigo Vergara Sandoval, Josefina Dib Hasan, Aldana Iaccarino, Frank Deroi Sánchez, Eduardo J Houghton

{"title":"[Prognostic Factors and Survival in Patients Undergoing Surgery for Pancreatic Ductal Adenocarcinoma: a MultiCenter Retrospective Analysis].","authors":"Sofía Gamboa Miño, Gustavo Kohan, Rodrigo Vergara Sandoval, Josefina Dib Hasan, Aldana Iaccarino, Frank Deroi Sánchez, Eduardo J Houghton","doi":"10.52787/agl.v55i2.482","DOIUrl":"10.52787/agl.v55i2.482","url":null,"abstract":"Introduction: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, with a five-year survival rate of less than 10%. Most patients are diagnosed at advanced stages, and both incidence and mortality are expected to rise over the next decade.Objectives: To estimate overall survival in patients undergoing surgery for pancreatic ductal adenocarcinoma and to analyze associated clinicopathological factors.Materials and methods: A multicenter, retrospective cohort study was condcuted. Patients who underwent surgery between January 2019 and December 2024 with histologically confirmed pancreatic ductal adenocarcinoma were included. Factors associated with overall survival were identified through multivariate analysis using Cox proportional hazards regression.Results: A total of 122 patients were evaluated. The mean age was 66.6 years, and 53.3% were female. Postoperative chemotherapy was administered in 62.3% of cases. The median overall survival was 31.7 months. Tumor recurrence occurred in 28.7% of patients, and 31.1% experienced postoperative complications. Multivariate analysis revealed that adjuvant chemotherapy was significantly associated with reduced mortality risk (HR 0.09; 95% CI: 0.04-0.21; p < 0.001). Tumor recurrence (HR 2.5; 95% CI: 1.25-5.03; p = 0.01) and histological tumor differentiation (HR 2.2; 95% CI: 1.214.00; p = 0.01) were associated with increased mortality.Conclusion: Surgery combined with adjuvant chemotherapy is significantly associated with improved survival in patients with pancreatic ductal adenocarcinoma. Conversely, tumor recurrence and histological tumor differentiation are linked to decreased survival.","PeriodicalId":35700,"journal":{"name":"Acta Gastroenterologica Latinoamericana","volume":"55 2","pages":"114-123"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variante anatómica biliar infrecuente observada mediante estudio endoscópico y colangioresonancia magnética. 通过内窥镜检查和磁血管共振观察到罕见的胆道解剖变异。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-06-30 eCollection Date: 2025-04-01 DOI: 10.52787/agl.v55i2.490

Iara Amira Yalis, Marcelo Milocco, Luis María Mercado, Pablo Alberto Farinelli

引用次数: 0

[Chronic Atrophic Gastritis in Hispanics Treated at a Second-Level Hospital: Results of a Retrospective and Single-Center Study]. [在二级医院治疗的西班牙裔慢性萎缩性胃炎：回顾性和单中心研究的结果]。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.52787/agl.v55i1.474

Leysi Carvache, John Daluz, Andrés Pereira-Reinosa, Kléber Coppiano, Byron Bermeo, Alberto Campodónico, Miguel Puga-Tejada

{"title":"[Chronic Atrophic Gastritis in Hispanics Treated at a Second-Level Hospital: Results of a Retrospective and Single-Center Study].","authors":"Leysi Carvache, John Daluz, Andrés Pereira-Reinosa, Kléber Coppiano, Byron Bermeo, Alberto Campodónico, Miguel Puga-Tejada","doi":"10.52787/agl.v55i1.474","DOIUrl":"10.52787/agl.v55i1.474","url":null,"abstract":"Introduction: The prevalence of chronic atrophic gastritis and intestinal metaplasia based on samples from third-level hospitals, may overestimate their frequency.Objetive: To estimate the frequency of premalignant histological lesions of the stomach in a second-level hospital.Material and methods: Observational, retrospective, descriptive, cross-sectional, epidemiological study. It was conducted with patients who had already undergone diagnostic upper digestive endoscopy, regardless of the clinical reason. Patients with gastrointestinal bleeding, tumors or without biopsy were excluded.Results: A total of 4454 cases were reviewed, of which 115 (2.6%, CI 2.2 - 3.1) had chronic atrophic gastritis. Compared to non-atrophic gastritis, the presence of chronic atrophic gastritis was more frequent in older adults (43.5% vs. 24.9%; p < 001) and in those with dyspepsia symptoms (35.7% vs. 19.9%; p < 0.001); and less frequent in economically active population (47.8% vs. 64.9%; p < 0.001). Among patients with chronic atrophic gastritis, nearly twice as many tested positive for Helicobacter pylori (47.8% vs. 25.6%; p < 0.001). Helicobacter pylori infection nearly tripled the risk of developing chronic atrophic gastritis (Odds Ratio 2.65; p < 0.001).Conclusion: In a second-level hospital, the prevalence of premalignant histological lesions is significantly lower than that reported by local studies conducted in third-level hospitals. The presence of chronic atrophic gastritis was associated with older age, indication for upper digestive endoscopy for dyspepsia, and Helicobacter pylori infection; while the indication for regurgitation was associated with its absence.","PeriodicalId":35700,"journal":{"name":"Acta Gastroenterologica Latinoamericana","volume":"55 1","pages":"37-44"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145669948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Annular Pancreas in Adults. A Case Report]. 成人环状胰腺。病例报告]。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.52787/agl.v55i1.424

Hernando Marulanda Fernández, Juan Sebastián Frías Ordoñez, William Otero Regino

{"title":"[Annular Pancreas in Adults. A Case Report].","authors":"Hernando Marulanda Fernández, Juan Sebastián Frías Ordoñez, William Otero Regino","doi":"10.52787/agl.v55i1.424","DOIUrl":"10.52787/agl.v55i1.424","url":null,"abstract":"Introduction: Annular pancreas is a rare congenital anomaly detected after the development of complications or as an incidental finding. Its diagnosis and treatment are controversial.Case presentation: A 44-year-old woman with chronic episodes of mild epigastric pain, nausea and emesis, with increasing frequency over the past two months. An abdominal ultrasound showed a distended gallbladder without stones, and dilated extrahepatic bile ducts. An endoscopic retrograde cholangiopancreatography was performed, revealing a circumferential pancreatic duct in the head of the pancreas surrounding the second part of the duodenum. By injecting contrast medium through the major papilla, its drainage was observed through a second, adjacent pore. Suspecting annular pancreas, magnetic resonance cholangiopancreatography was performed, showing a complete annular pancreatic duct. In the presence of recurrent symptoms of abdominal pain, the patient was referred to hepatobiliary surgery for definitive surgical management.Conclusions: Annular pancreas is a diagnosis to be considered in adults in case of epigastric pain associated with non-specific symptoms. Advances in imaging methods make its diagnosis timely. Despite the lack of guidelines on treatment, this must be individualized on a case-by-case basis.","PeriodicalId":35700,"journal":{"name":"Acta Gastroenterologica Latinoamericana","volume":"55 1","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145669925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[[Win Ratio: A Different Way to Analyze Clinical Trials. Its Strengths and Weaknesses]]. 胜率：分析临床试验的不同方法。它的优点和缺点]]。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.52787/agl.v55i1.477

Walter Masson

引用次数: 0

[Contributions of Nuclear Medicine to Gastroenterology: Use of Gastric Emptying Scintigraphy and Other Studies in Functional Gastrointestinal Pathology]. [核医学对胃肠病学的贡献：胃排空显像的使用和功能性胃肠病理学的其他研究]。

Acta Gastroenterologica Latinoamericana Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.52787/agl.v55i1.472

Gerardo Rank

引用次数: 0