Marco Antonio Romero, Paula García Ledesma, Iñaki Cornago, Ainhoa Hernando, Isabel Gallardo, Rosa Inés Muñoz, Iñaki Minguela, Isabel Martínez, Jesús Montenegro
{"title":"Leptospirosis con fracaso multiorgánico – Síndrome de Weil","authors":"Marco Antonio Romero, Paula García Ledesma, Iñaki Cornago, Ainhoa Hernando, Isabel Gallardo, Rosa Inés Muñoz, Iñaki Minguela, Isabel Martínez, Jesús Montenegro","doi":"10.1016/S0304-4858(10)70035-4","DOIUrl":"10.1016/S0304-4858(10)70035-4","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 4","pages":"Page 138"},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70035-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56308150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vidas y muertes de Luis Martín-Santos","authors":"Pedro Gorrotxategi Gorrotxategi","doi":"10.1016/S0304-4858(10)70037-8","DOIUrl":"10.1016/S0304-4858(10)70037-8","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 4","pages":"Pages 141-142"},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70037-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91081827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mensaje del Presidente de la Academia de Ciencias Médicas de Bilbao","authors":"Juan Ignacio Goiria-Ormazabal","doi":"10.1016/S0304-4858(10)70030-5","DOIUrl":"10.1016/S0304-4858(10)70030-5","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 4","pages":"Pages 113-114"},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70030-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56307780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Felipe Reoyo Pascual, Rosa María Martínez Castro, José Andrés Ortega Seda, Raquel León Miranda, Juan Luis Seco Gil
{"title":"Procalcitonina y sepsis en pacientes de cirugía general","authors":"José Felipe Reoyo Pascual, Rosa María Martínez Castro, José Andrés Ortega Seda, Raquel León Miranda, Juan Luis Seco Gil","doi":"10.1016/S0304-4858(10)70032-9","DOIUrl":"10.1016/S0304-4858(10)70032-9","url":null,"abstract":"<div><p>In the last few years, the utility of procalcitonin (PCT) as a marker of severity of sepsis has been studied. PCT values may be useful in differentiating septic stages and in predicting postoperative complications. The principal objectives of our study were to demonstrate that PCT is a useful and early marker in the diagnosis and differentiation of sepsis in surgical patients and to assess PCT levels in the diagnosis of postoperative infectious complications.</p><p>We performed a prospective study to evaluate a diagnostic test in 75 patients from March to July 2009 by establishing two groups: the first group consisted of patients with infectious diseases (acute cholecystitis, acute diverticulitis, mesenteric ischemia and gastrointestinal perforations) and the second group comprised patients with non-infectious diseases who developed infectious complications (urinary tract infection, catheter-associated bacteremia, pneumonia, intraabdominal abscess, surgical wound infection and anastomotic dehiscence) during the postoperative period.</p><p>The results showed that PCT values were elevated in septic processes. Moreover, the higher these values, the greater the severity of the process.</p><p><strong>Laburpena</strong></p><p>Azken urteotan, prokalzitonina (PCT) sepsiaren larritasunaren adierazle modura erabiltzeko aukera ikertu da, bere balioak fase septikoen bereizkuntzari lotuz eta baita operazio ondoko zailtasunen igarle gisa ere. Gure azterketaren helburu nagusiak dira, batetik, prokalzitonina patologia kirurgikoko pazienteengan sepsia bereizteko eta diagnostikatzeko adierazle erabilgarri eta goiztiarra dela erakustea, eta, bestetik, operazio ondoko konplikazio infekziosoen diagnostikoan prokalzitonina mailak ebaluatzeko modua erakustea.</p><p>Ikerketa Deskriptibo Prospektibo bat egin zen 2009ko uztailetik martxora, 75 pazienteen proba diagnostikoa ebaluatzeko, eta bi talde bereizi ziren: lehenengoan, patologia infekziosoa zuten pazienteak zeuden (kolezisititis akutua, dibertikulitis akutua, iskemia mesenterikoa eta urdai eta hesteetako zulaketak), eta, bigarren taldean, berriz, patologia ez-infekziosoagatik operatuak izan ziren eta gero konplikazio infekziosoak izan zituzten pazienteak, hala nola gernu hodiaren infekzioa, kateterrari lotutako bakteriemia, pneumonía, abdomen-barneko abszesua, infekzioa zauri kirurgikoan eta anastomosiko dehiszentzia.</p><p>Lortutako emaitzek agerian utzi dute prozesu septiko baten aurrean prokalzitoninaren balioak igotzen direla, eta, gainera, balioak are gehiago igotzen direla prozesuaren larritasuna areagotu ahala.</p></div>","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 4","pages":"Pages 123-127"},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70032-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56307853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Roberto Nóvoa Santos (1885–1933) Precursor del tratamiento de la diabetes con incretinas","authors":"Pedro Gorrotxategi Gorrotxategi","doi":"10.1016/S0304-4858(10)70036-6","DOIUrl":"10.1016/S0304-4858(10)70036-6","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 4","pages":"Pages 139-140"},"PeriodicalIF":0.0,"publicationDate":"2010-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70036-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82354295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ignacia Idarreta , Eva Rua , Francisco Javier Hernando , Koro Zabaleta , María Jesús Arzuaga , María Isabel Irizar
{"title":"Consumidores, prescripción y prescriptores de fármacos para la osteoporosis","authors":"Ignacia Idarreta , Eva Rua , Francisco Javier Hernando , Koro Zabaleta , María Jesús Arzuaga , María Isabel Irizar","doi":"10.1016/S0304-4858(10)70024-X","DOIUrl":"10.1016/S0304-4858(10)70024-X","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the characteristics of prescribers and consumers of osteoporosis drugs.</p></div><div><h3>Design</h3><p>Cross-sectional study.</p></div><div><h3>Setting</h3><p>34 primary care areas for the county of West Gipuzkoa (Spain).</p></div><div><h3>Participants</h3><p>People older than 13 years, randomly selected from 1673 persons consuming osteoporosis drugs for 1 year.</p></div><div><h3>Intervention</h3><p>A questionnaire completed through clinical interview and data from the medical record.</p></div><div><h3>Main measurements</h3><p>Risk factors, drugs, bone mineral density (BMD), prescribers, fracture risk.</p></div><div><h3>Results</h3><p>We studied 512 persons (90.6% women), with a mean age of 68.9 years, taking 898 drugs for osteoporosis. A total of 24.6% had a history of fracture before the age of 50 years and 21.5% of women were fertile for less than 30 years. BMD was available in 50.4%; of these, 52.8% were osteoporotic. One in three BMD scans performed were not justified. The most widely prescribed drug was calcium, with or without vitamin D (53.4%), followed by biphosphonates (33.95%). Prescriptions were issued by rheumatologists (29.2%), traumatologists, gynecologists and primary care physicians (12.4%). One-third (30.6%) were not based on the best evidence. According to the Black scale, 23.8 ± 3.9% had a high risk of fracture (37.8% primary care, 0% gynecology).</p></div><div><h3>Conclusions</h3><p>Osteoporosis drugs are being used when not warranted by BMD, risk factors or fracture risk. Specialists prescribe these drugs as much or more than primary care physicians. Standardization of criteria for the rational management of this disease is imperative.</p></div>","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 3","pages":"Pages 90-96"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70024-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56307697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ángel San Miguel , Francisco Javier Martin Gil , Alicia Armentia Medina , B. Martin Armentia
{"title":"Principales técnicas de diagnóstico de las reacciones alérgicas a fármacos","authors":"Ángel San Miguel , Francisco Javier Martin Gil , Alicia Armentia Medina , B. Martin Armentia","doi":"10.1016/S0304-4858(10)70027-5","DOIUrl":"10.1016/S0304-4858(10)70027-5","url":null,"abstract":"<div><p>Anaphylactic reactions due to muscle relaxants and other drugs that induce IgE-mediated sensitivity are highly prevalent. Because of false-positive and false-negative results in skin tests and the lack of provocation tests with some drugs (e.g., general anesthetics), diagnosis is often difficult. An alternative is to assay leukotrienes, which are chemical mediators that also contribute to inflammation in asthma and allergic rhinitis. In this brief report, we describe the cellular antigen stimulation test (CAST), a quick and easy to perform assay for peptide-sulfido-leukotrienes and compare this test with traditional <em>in vitro</em> assays.</p></div>","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 3","pages":"Pages 105-108"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70027-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56307716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congreso Internacional de Crónicos 2010, Bilbao, País Vasco, España","authors":"Julen Ocharan-Corcuera","doi":"10.1016/S0304-4858(10)70028-7","DOIUrl":"10.1016/S0304-4858(10)70028-7","url":null,"abstract":"","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 3","pages":"Pages 109-110"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70028-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56307765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yolanda Sáez Meabe , Marta Vacas Rius , Mónica Santos Gutiérrez , Jesús Pablo Sáez de Lafuente Chivite , José Domingo Sagastagoitia Gorostiza , Enrique Molinero de Miguel , José Antonio Iriarte Ezcurdia , José Manuel de Gandarias Bajón
{"title":"Evaluación de los datos obtenidos sobre factores de riesgo cardiovascular en las Semanas de Prevención de la Arteriosclerosis y Enfermedades Cardiovasculares (2000–2008)","authors":"Yolanda Sáez Meabe , Marta Vacas Rius , Mónica Santos Gutiérrez , Jesús Pablo Sáez de Lafuente Chivite , José Domingo Sagastagoitia Gorostiza , Enrique Molinero de Miguel , José Antonio Iriarte Ezcurdia , José Manuel de Gandarias Bajón","doi":"10.1016/S0304-4858(10)70023-8","DOIUrl":"10.1016/S0304-4858(10)70023-8","url":null,"abstract":"<div><h3>Objective</h3><p>To study trends in the cardiovascular risk factors analyzed during the Arteriosclerosis and Cardiovascular Disease Prevention Weeks held in Bilbao from 2000 to 2008.</p></div><div><h3>Material and methods</h3><p>All participants completed a questionnaire on their history of cardiovascular disease and daily habits and underwent clinical and laboratory tests<em>.</em></p></div><div><h3>Results</h3><p>Results were obtained from a total of 4,695 persons with a mean age of 65.22 ± 12.16 years. Over the study period, hypertension and cholesterol values decreased, with a steady and significant increase in treatments for high blood pressure and hypercholesterolemia. There was almost no change in body mass index, but there was a steady increase in moderate and intense exercise, as well as a decrease in smoking.</p></div><div><h3>Conclusions</h3><p>The results obtained confirm that the Arteriosclerosis and Cardiovascular Disease Prevention Weeks appear to have been effective, given the substantial reductions detected in the prevalence of cardiovascular risk factors.</p></div>","PeriodicalId":35686,"journal":{"name":"Gaceta Medica de Bilbao","volume":"107 3","pages":"Pages 84-89"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0304-4858(10)70023-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85466569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}