Camilo Arenas-Gallo, Gabriela Ramírez-Rocha, Laura González-Hakspiel, Catalina Merlano-Alcendra, Daniela Palomino-Suárez, Santiago Rueda-Espinel
{"title":"Acceptability and safety of the menstrual cup: A systematic review of the literature","authors":"Camilo Arenas-Gallo, Gabriela Ramírez-Rocha, Laura González-Hakspiel, Catalina Merlano-Alcendra, Daniela Palomino-Suárez, Santiago Rueda-Espinel","doi":"10.18597/rcog.3425","DOIUrl":"10.18597/rcog.3425","url":null,"abstract":"<p><strong>Objectives: </strong>To conduct a systematic review of the literature and assess the acceptability and safety of the menstrual cup as a feminine hygiene product.</p><p><strong>Materials and methods: </strong>A search was conducted in the PubMed, Cochrane Library, Scopus, PopLine and Google Scholar databases for publications be- tween 1966 and July 2019. The terms (\"Menstrual\" AND \"Cup\") OR (\"Copa\" AND \"Menstrual\") were used. Quantitative, qualitative and mixed studies were included, as well as case series and case reports published in English and Spanish assessing the menstrual cup in women in childbearing age. The studies were selected and the data extracted by two reviewers working independently. Acceptability and safety were assessed as the primary result. The summary of the information is presented in narrative form.</p><p><strong>Results: </strong>Overall, 737 titles were found for initial review and, in the end, 38 studies were included in this work. The acceptability of the menstrual cup ranges between 35 % and 90 %. Between 10 to 45 % of women found it difficult to use. It was described as more comfortable when compared to tampons and pads. Continued use of the cup ranges between 48 and 94 %. In terms of safety, there was one case of toxic shock syndrome, one case of mechanical entrapment, and another case of allergy; and a higher risk of expulsion was found among intrauterine device users.</p><p><strong>Conclusion: </strong>The menstrual cup appears to be a comfortable, safe and efficient option for menstrual hygiene. Further randomized controlled studies and long-term prospective cohort studies are needed in order to determine the risk of complications due to excess bacterial colonization or retrograde menstruation.</p>","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10216001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana Cristina Martínez-Pérez, Luis Rodolfo Gómez-Wolff, Carlos Andrés Ossa-Gómez, Gilma Norela Hernández-Herrera, Yamile Rivas-Bedoya, Héctor Iván García-García
{"title":"[Association between delayed diagnosis and breast cancer in advanced clinical stage at the time of consultation in four oncology centers in Medellin- Colombia, 2017. Cross-sectional study].","authors":"Diana Cristina Martínez-Pérez, Luis Rodolfo Gómez-Wolff, Carlos Andrés Ossa-Gómez, Gilma Norela Hernández-Herrera, Yamile Rivas-Bedoya, Héctor Iván García-García","doi":"10.18597/rcog.3410","DOIUrl":"https://doi.org/10.18597/rcog.3410","url":null,"abstract":"<p><strong>Objective: </strong>To determine the association between delayed diagnosis and advanced clinical stage breast cancer, and to explore the factors that influence this delay.</p><p><strong>Methods: </strong>Cross-sectional study of women over 18 years of age with breast cancer who attended 4 oncology centers in Medellín, Colombia, in 2017. The \"Breast Cancer Delay Questionnaire\" which includes sociodemographic and clinical variables as well as time intervals was used. Crude and adjusted odds ratio (OR) were estimated, using advanced clinical stage as outcome and delayed diagnosis as exposure.</p><p><strong>Results: </strong>42 patients were included. The median time interval between the identification of the problem and the diagnostic biopsy was 104.5 days; between the identification of the problem and the first medical visit, 20 days; and between the first visit and the diagnostic biopsy, 53 days. Of all the cases, 52.1 % were diagnosed at an advanced stage. An association was found between delayed diagnosis and advanced clinical stage (OR = 2.15 95 % CI 1.21-3.79). Age above 40 was found to be a protective factor against having an advanced-stage lesion (OR = 0.35; 95 % CI: 0.14-0.83). Delayed diagnosis was associated with affiliation to the government subsidized health system (OR = 9.67; 95 % CI 2.76- 33.9) and age over 40 years (OR = 2.75; 95 % CI1.16-6.53).</p><p><strong>Conclusions: </strong>Patient education is required in order to ensure adherence to early screening programs or timely consultation whenever a sign or symptom is identified, thus allowing diagnosis at an early stage of the disease. Moreover, prospective studies are needed in order to identify factors associated with delays in treatment after the diagnosis of breast cancer, and to assess interventions designed to reduce delays in the care of this form of cancer.</p>","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38245004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kelly Estrada-Orozco, Francy Cantor-Cruz, Diego Larrotta-Castillo, Stefany Díaz-Ríos, Miguel A Ruiz-Cardozo
{"title":"Central venous catheter insertion and maintenance: Evidence-based clinical recommendations","authors":"Kelly Estrada-Orozco, Francy Cantor-Cruz, Diego Larrotta-Castillo, Stefany Díaz-Ríos, Miguel A Ruiz-Cardozo","doi":"10.18597/rcog.3413","DOIUrl":"10.18597/rcog.3413","url":null,"abstract":"<p><strong>Objective: </strong>To share with clinicians supporting evidence of the safest and the most effective processes for central venous catheter insertion and maintenance as a strategy to prevent catheter-associated bloodstream infections.</p><p><strong>Methods: </strong>A literature search was conducted in the Medline via PubMed, Embase Central and Lilacs databases based on a set of clinical questions aimed at improving safety and effectiveness at key moments in the process of central venous catheter insertion and maintenance. The rapid literature review methodology was used. The studies identified were assessed from the quality point of view, using the Joanna Briggs Institute (JBI) tools for qualitative and quantitative studies and for systematic reviews. Clinical practice guidelines were assessed using the AGREE II tool. The evidence is presented in the form of evidence-based clinical recommendations, which were graded in accordance with the JBI methodology.</p><p><strong>Results: </strong>Twelve clinical evidence summaries containing evidence related to the safe and effective use of central venous catheters are presented, including the following topics: central venous catheter insertion (CVC), peripherally inserted central catheters (PICC), preoperative assessment, the use of analgesia, field preparation, choice between CVC or PICC, CVC care and maintenance, prevention of complications, and general considerations pertaining to the use of central venous catheters in oncologic patients and in parenteral nutrition.</p><p><strong>Conclusions: </strong>Recommendations on the safe and effective use of central venous access catheters in relation to CVC insertion and maintenance processes are presented in the evidence-based summary model. It is necessary to evaluate their implementation in health outcomes in the institutions where they are developed.</p>","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10222895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafael Leonardo Aragón-Mendoza, Jaime Arenas-Gamboa, Santiago Vieira-Serna, Isaac Alfonso Juan Sierra
{"title":"Primary retroperitoneal tumor during pregnancy: Case report and review of the literature","authors":"Rafael Leonardo Aragón-Mendoza, Jaime Arenas-Gamboa, Santiago Vieira-Serna, Isaac Alfonso Juan Sierra","doi":"10.18597/rcog.3477","DOIUrl":"10.18597/rcog.3477","url":null,"abstract":"<p><strong>Objective: </strong>To report the case of a pregnant patient diagnosed with a primary retroperitoneal tumor and to conduct a review of the literature pertaining to the diagnosis, treatment and maternal-fetal prognosis of this disease condition during pregnancy.</p><p><strong>Methods: </strong>A 19-year-old patient who presented with a retroperitoneal tumor identified on ultrasound. The results of the percutaneous biopsy showed a benign tumor. A healthy neonate was delivered by cesarean section. Surgical resection was performed four months later, and histopathology showed a mature cystic teratoma. A search was conduced in the Medline via PubMed, Lilacs, SciELO and ScienceDirect databases using the terms \"pregnancy,\" \"neoplasms,\" and \"retroperitoneal neoplasms,\" including case reports and case series of retroperitoneal tumors during pregnancy. Diagnosis, treatment and maternal-fetal prognosis were identified.</p><p><strong>Results: </strong>Overall, 1658 titles were identified. Of these, 34 case reports and 1 case series met the inclusion criteria. Of the cases, 62.9 % were benign. Diagnosis was made as an incidental finding in 63 % of cases, and 77 % of the masses were identified on ultrasound. Percutaneous biopsy was used in 8 % of cases, including the case reported here. Surgical treatment was used in 88 % of cases usually after delivery. Maternal mortality occurred in 8.5 % of cases. Fetal prognosis was good in 65 % of the pregnancies.</p><p><strong>Conclusions: </strong>Despite being frequently benign, retroperitoneal tumors during gestation have a reserved maternal and fetal prognosis in a substantial number of cases. There is a need to assess the risks and benefits of percutaneous biopsy.</p>","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10222900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karen Rodríguez-Soto, Sara Reyes-Aranibar, Tula Uribe-Chincha, Paola Torres-Slimming
{"title":"[Comments on: \"Family life stories in teenage mothers: Qualitative study conducted at the Engativá ESE Hospital in Bogotá, Colombia\"].","authors":"Karen Rodríguez-Soto, Sara Reyes-Aranibar, Tula Uribe-Chincha, Paola Torres-Slimming","doi":"10.18597/rcog.3452","DOIUrl":"https://doi.org/10.18597/rcog.3452","url":null,"abstract":"Carta al editor del 17 de noviembre de 2019 sobre el artículo “Historias de vida familiar en madres adolescentes: estudio cualitativo realizado en el Hospital Engativá ESE en Bogotá, Colombia” https://doi.org/10.18597/rcog.3162","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38242933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Walter Osorio-Ramírez, Juan Giraldo-Moreno, Diana Gómez-Cortés, David Olive, John Cano-Franco, Sergio Tamayo-Hussein
{"title":"BIRTH OF HEALTHY NEONATE FOLLOWING PREIMPLANTATION GENETIC DIAGNOSIS IN A MOTHER WITH MOSAIC TURNER SYNDROME. CASE REPORT AND REVIEW OF THE LITERATURE.","authors":"Walter Osorio-Ramírez, Juan Giraldo-Moreno, Diana Gómez-Cortés, David Olive, John Cano-Franco, Sergio Tamayo-Hussein","doi":"10.18597/rcog.3331","DOIUrl":"https://doi.org/10.18597/rcog.3331","url":null,"abstract":"<p><strong>Objective: </strong>To report the case of a patient with mosaic Turner syndrome who underwent assisted reproduction treatment with preimplantation genetic testing for aneuploidy and gave birth to a healthy baby girl with normal karyotype; and to conduct a review of the literature on the usefulness of preimplantation genetic diagnosis in women with Turner syndrome.</p><p><strong>Methods: </strong>A case of a 27 year-old woman diagnosed with mosaic Turner syndrome and secondary altered ovarian reserve, seen in a referral center for infertility management in Medellín, Colombia. The patient underwent in vitro fertilization followed by pre-implantation genetic testing to prevent transmission of Turner syndrome to her progeny. A literature search was conducted in the Medline via PubMed, Clinical Key, OVID, Embase, Lilacs, SciELO and Oxford Journals databases using the following terms: \"Turner Syndrome,\" \"Mosaic Turner,\" \"Preimplantation Genetic Screening,\" \"Preimplantation Genetic Testing,\" \"Preimplantation Genetic Diagnosis,\" \"Pregnancy,\" \"Successful pregnancy.\" Inclusion criteria were case series and case reports, cohort studies and review articles published between January 1980 and June 2017 that included women with Turner syndrome achieving pregnancy by means of in vitro fertilization techniques with their own oocytes and who had undergone embryo biopsy for preimplantation genetic diagnosis. The search was limited to articles in Spanish and English.</p><p><strong>Results: </strong>one study met the inclusion criteria. Both in this report and in our case, patients with mosaic Turner syndrome underwent several cycles of intracytoplasmic sperm injection (ICSI) with their own eggs, then performed embryonic biopsy for preimplantation genetic analysis using different techniques. In both cases, euploid embryos were transferred to the uterus with the subsequent birth of healthy girls with normal karyotype.</p><p><strong>Conclusions: </strong>Patients with mosaic Turner syndrome could benefit from preimplantation biopsy and genetic analysis to prevent transmission of the genetic defect to their progeny.</p>","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37945198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RESILIENCE AND COVID-19.","authors":"Armando Solano Gámez","doi":"10.18597/rcog.3531","DOIUrl":"https://doi.org/10.18597/rcog.3531","url":null,"abstract":"","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37945720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[DIFFERENCES IN SEXUAL NEGOTIATION STYLES AND SEXUAL SELF-EFFICACY IN USE OF CONDOM IN UNIVERSITY MEN AND WOMAN OF QUERETARO, MEXICO, 2018].","authors":"Jorge Raúl Palacios-Delgado, Nuria Ortego-García","doi":"10.18597/rcog.3327","DOIUrl":"https://doi.org/10.18597/rcog.3327","url":null,"abstract":"<p><strong>Objective: </strong>To compare sexual negotiation levels and self-efficacy in male condom use in men and women.</p><p><strong>Methods: </strong>Comparative crosssectional study of undergraduate students carried out during the year 2018 in a private university in the city of Querétaro, Mexico. Non-probabilistic sampling was used. Measured variables included sociodemographic characteristics, risky sexual behaviors, negotiation skills and sexual self-efficacy for condom use. The Mann Whitney U test and non-parametric variance analysis (Kruskal - Wallis) were used.</p><p><strong>Results: </strong>Overall, 270 students were enrolled; 89.6% of university students were sexually active; the mean age of sexual activity initiation was 15.41 years. The average reported number of sexual partners was 4.2. In each sexual relation, 27.8% had used a condom. Differences were found between men and women in terms of sexual negotiation styles in the avoidance (p=0.04) and accommodation (p<0.00) domains, with higher scores for men compared to women. Women scored higher for self-efficacy in condom use (p<0.001).</p><p><strong>Conclusions: </strong>The young university students interviewed engage in risky sexual activities. Women exhibit greater sexual self-efficacy as well as better skills at negotiating condom use. Strengthening public policies targeted to the student population for the prevention of risky sexual behavior is needed. Further studies on interventions aimed at building strong sexual negotiation and self-efficacy among adolescents are required.</p>","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37945721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STUDY OF AGREEMENT BETWEEN THE ROSSO-MARDONES AND ATALAH SCALES FOR NUTRITIONAL ASSESSMENT IN PREGNANCY. LA ERMITA CLINIC, CARTAGENA, 2017.","authors":"Edgar E Rivas-Perdomo, Martha Galván-Villa","doi":"10.18597/rcog.3317","DOIUrl":"https://doi.org/10.18597/rcog.3317","url":null,"abstract":"OBJECTIVE To assess the degree of agreement between the model for maternal nutritional assessment proposed by Rosso-Mardones and the one proposed by Atalah. METHODS Diagnostic agreement study. Pregnant women between the ages of 19 and 37 years with a gestational age of 10 or more weeks were incuded; patients with diabetes, thyroid disease, pregnancy-associated hypertension, twin pregnancy, severe fetal malformation, fetal death and hydrops fetalis were excluded. Non-probabilistic sampling. Sociodemographic, obstetrical and nutritional status variables were measured. RESULTS Overall, 98 pregnant women were included. With the use of the Rosso-Mardones scale, 33% of the patients were classified as having a normal nutritional status, 22% as low weight, and 44% as overweight or obese. With the Atalah scale, 41% of the women were classified as having a normal nutritional status, 10% as low weight and 48% as overweight or obese. The weighted kappa value was 0.74 with a standard error of 0.04, a 95% CI of 0.66-0.82 and a p value < 0.05. CONCLUSIONS There is substantial agreement between nutritional assessment scales used in pregnancy, namely the Rosso-Mardones nomogram and the Atalah scale. Further studies to assess the agreement of these scales in the pregnant population are required.","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37945723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nathalia Mora-Soto, Luis Alejandro Villegas-Agudelo, Lissette Alejandra López-Moreno, Carlos Alberto Ramírez-Serrano, Jorge Andrés Rubio-Romero
{"title":"RISK OF NEONATAL HOSPITALIZATION ASSOCIATED TO DELIVERY BY CESAREAN SECTION IN A HIGH COMPLEXITY CLINIC IN BOGOTÁ, COLOMBIA, 2018.","authors":"Nathalia Mora-Soto, Luis Alejandro Villegas-Agudelo, Lissette Alejandra López-Moreno, Carlos Alberto Ramírez-Serrano, Jorge Andrés Rubio-Romero","doi":"10.18597/rcog.3364","DOIUrl":"https://doi.org/10.18597/rcog.3364","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the association between cesarean delivery and hospitalization of the newborn and describe the indications for cesarean according to Robson's groups in the obstetrics service of a highly complex general institution.</p><p><strong>Methods: </strong>Cross-sectional study. All births occurred between March and July 2018 in a high complexity general teaching hospital in Bogotá, Colombia were included, by consecutive sampling up to a sample size of 1040 pregnant women. The frequency of caesarean section, indications, neonatal outcomes for each Robson group, and the risk of neonatal hospitalization are described using the crude and adjusted odds ratio (OR) using multivariate analysis.</p><p><strong>Results: </strong>1,493 births were included, of which 539 (36.3 %) were by cesarean section. Women with a history of uterine scar scheduled for elective caesarean section and those hospitalized for induction provide the majority of caesarean sections. The main indications for cesarean section were suspicion of unsatisfactory fetal status and prolongued labor. Adjusted for birth weight, caesarean section increased the overall risk of neonatal hospitalization (adjusted OR [aOR] = 2,2; IC 99 %: 1,3-3,7).</p><p><strong>Conclusions: </strong>There are groups of Robson susceptible of intervention to decrease the rate of caesarean sections due to the suspicion of unsatisfactory fetal status and prolongation of labor. An association was found between cesarean delivery and subsequent neonatal hospitalization. Randomized controlled studies are required to determine the benefit of the strategies to reduce cesarean section rates and evaluate the association found.</p>","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37945724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}