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Ensuring High-Quality Colonoscopy: A Review. 确保高质量结肠镜检查：综述。
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2025-10-16 DOI: 10.1016/j.giec.2025.09.001
Rachael Hagen, Joseph C Anderson
{"title":"Ensuring High-Quality Colonoscopy: A Review.","authors":"Rachael Hagen, Joseph C Anderson","doi":"10.1016/j.giec.2025.09.001","DOIUrl":"https://doi.org/10.1016/j.giec.2025.09.001","url":null,"abstract":"<p><p>Colonoscopy prevents colorectal cancer through polyp detection and resection. High-quality colonoscopy is important for optimal detection of adenomas and serrated polyps and mitigating the risk of postcolonoscopy colorectal cancer (PCCRC). Optimal bowel preparation quality is also important in reducing PCCRC incidence. Key performance metrics described in this article include bowel preparation adequacy rate, cecal intubation rate, adenoma detection rate, adenomas per colonoscopy, sessile serrated lesion detection rate, and withdrawal time. This article also addresses appropriate colonoscopy indications, proper procedure documentation, and recommended screening and surveillance intervals.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"689-701"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Blood-Based Tests for Colorectal Cancer Screening. 结直肠癌筛查的新型血液检测
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-04-08 DOI: 10.1016/j.giec.2026.02.005
Angela Z Xue, Cyrus Daruwalla, Peter S Liang
{"title":"Novel Blood-Based Tests for Colorectal Cancer Screening.","authors":"Angela Z Xue, Cyrus Daruwalla, Peter S Liang","doi":"10.1016/j.giec.2026.02.005","DOIUrl":"https://doi.org/10.1016/j.giec.2026.02.005","url":null,"abstract":"<p><p>Blood-based tests are a novel colorectal cancer (CRC) screening modality that can potentially improve screening uptake due to greater convenience and patient preference for blood tests. To date, 3 blood-based CRC screening tests have completed large validation studies (Epi proColon, Shield, and the Freenome test). Multi-cancer early detection tests are also actively being investigated for their role in CRC screening. Despite various benefits, blood-based screening tests also have several limitations, including low sensitivity for advanced precancerous lesions, low rates of follow-up colonoscopy after an abnormal test, and concerns about cost-effectiveness.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"673-688"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening for Colorectal Cancer with Stool Tests. 用粪便试验筛查结直肠癌
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-05-05 DOI: 10.1016/j.giec.2026.02.003
Adam L Urback, Seth D Crockett
{"title":"Screening for Colorectal Cancer with Stool Tests.","authors":"Adam L Urback, Seth D Crockett","doi":"10.1016/j.giec.2026.02.003","DOIUrl":"https://doi.org/10.1016/j.giec.2026.02.003","url":null,"abstract":"<p><p>This article reviews the performance, limitations, and implementation challenges of stool-based colorectal cancer (CRC) screening. Stool-based tests are becoming more essential in CRC screening due to their accessibility, affordability, and noninvasive nature. While screening performance varies among modalities, adherence to testing and timely follow-up remains the main barrier to effectiveness. Fecal immunochemical test (FIT) offers a favorable balance of sensitivity, cost, and patient uptake. Newer DNA-based and RNA-based tests improve early-stage cancer detection but are costlier and marginally less specific. Optimizing adherence while balancing diagnostic yield, cost, and environmental impact is essential to advancing stool-based CRC screening.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"639-658"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Changing Epidemiology of Colorectal Cancer. 结直肠癌流行病学的变化
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-05-05 DOI: 10.1016/j.giec.2026.02.002
Allison Janak, Janice Cheong
{"title":"The Changing Epidemiology of Colorectal Cancer.","authors":"Allison Janak, Janice Cheong","doi":"10.1016/j.giec.2026.02.002","DOIUrl":"https://doi.org/10.1016/j.giec.2026.02.002","url":null,"abstract":"<p><p>This article traces the historical changes in colorectal cancer (CRC) epidemiology both globally and in the United States, highlighting current challenges such as the rising incidence of early-onset CRC and persistent racial disparities in CRC incidence, mortality, and survival, as well as future directions for improving health inequities in CRC.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"607-619"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors for Colorectal Cancer, including Early Onset. 结直肠癌的危险因素，包括早期发病。
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-06-17 DOI: 10.1016/j.giec.2026.05.001
Swati Patel, Robin B Mendelsohn
{"title":"Risk Factors for Colorectal Cancer, including Early Onset.","authors":"Swati Patel, Robin B Mendelsohn","doi":"10.1016/j.giec.2026.05.001","DOIUrl":"https://doi.org/10.1016/j.giec.2026.05.001","url":null,"abstract":"<p><p>Colorectal cancer (CRC) arises from genetic, environmental, and lifestyle factors. Recognizing these risks helps clinicians identify high-risk patients and guide prevention. Risk factors are grouped as nonmodifiable (age, family history, race/ethnicity, prior abdominal/pelvic radiation, or inflammatory bowel disease) and modifiable (obesity, diet, inactivity, alcohol, or tobacco). The growing incidence of early-onset CRC (diagnosed before 50) is a particular concern and highlighted throughout this section.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"621-637"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances and Challenges to Colonoscopy Quality. 结肠镜检查质量的进展与挑战。
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-07-10 DOI: 10.1016/j.giec.2026.04.001
Haidar Khan, Ramya Vasireddy, Mahnoor Khan, Rashmi Advani
{"title":"Advances and Challenges to Colonoscopy Quality.","authors":"Haidar Khan, Ramya Vasireddy, Mahnoor Khan, Rashmi Advani","doi":"10.1016/j.giec.2026.04.001","DOIUrl":"https://doi.org/10.1016/j.giec.2026.04.001","url":null,"abstract":"<p><p>Colorectal cancer is the third most common type of cancer by incidence and the second most common cause of cancer-related death in the United States. Colonoscopy is the gold standard in diagnosis and can additionally provide therapeutic interventions. This article outlines current advances, challenges, and best practices in regard to high-quality colonoscopy.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"703-718"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Artificial Intelligence Assistance to Improve Colonoscopy. 使用人工智能辅助改善结肠镜检查。
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-07-10 DOI: 10.1016/j.giec.2026.05.003
Prahan Chetlur, Abraham Z Cheloff, Maysaa El Zoghbi
{"title":"Use of Artificial Intelligence Assistance to Improve Colonoscopy.","authors":"Prahan Chetlur, Abraham Z Cheloff, Maysaa El Zoghbi","doi":"10.1016/j.giec.2026.05.003","DOIUrl":"https://doi.org/10.1016/j.giec.2026.05.003","url":null,"abstract":"<p><p>Artificial intelligence is increasingly embedded in colonoscopy to enhance detection, standardize optical diagnosis, and support quality metrics. Randomized trials show that computer-aided detection raises adenoma detection and lowers miss rates, while real-world gains are smaller and variable. Computer-aided diagnosis can facilitate resect-and-discard and diagnose-and-leave when performance meets American Society of Gastrointestinal Endoscopy (ASGE) Preservation and Incorporation of Valuable Endoscopic Innovations (PIVI) thresholds and is strongest as an adjunct to expert assessment. This article highlights the current evidence base, remaining limitations, and key considerations for clinical adoption.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"737-749"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effective Polypectomy Practice. 有效的息肉切除术实践。
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-06-22 DOI: 10.1016/j.giec.2026.05.002
Malique Delbrune, Thomas Enke, Mohammad Bilal
{"title":"Effective Polypectomy Practice.","authors":"Malique Delbrune, Thomas Enke, Mohammad Bilal","doi":"10.1016/j.giec.2026.05.002","DOIUrl":"https://doi.org/10.1016/j.giec.2026.05.002","url":null,"abstract":"<p><p>Colorectal cancer (CRC) is one of leading causes of cancer-related morality globally. Colonoscopy with polypectomy allows for resection of dysplastic polyps and early CRC, and has been shown to reduce the incidence of CRC and CRC-related morality. This article highlights several important aspects of an effective polypectomy practice including visual inspection, polypectomy techniques, and their respective indications, adverse events, and indications for referral. Most endoscopists will not be competent in all polypectomy and resection techniques on completion of training and ongoing education is paramount as we aim to reduce to incidence, morbidity, and mortality associated with CRC.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"719-736"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complications of Colonoscopy and How to Reduce Them. 结肠镜检查的并发症及如何减少。
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-06-08 DOI: 10.1016/j.giec.2026.04.002
Radhika Chavan, Shivangi T Kothari
{"title":"Complications of Colonoscopy and How to Reduce Them.","authors":"Radhika Chavan, Shivangi T Kothari","doi":"10.1016/j.giec.2026.04.002","DOIUrl":"https://doi.org/10.1016/j.giec.2026.04.002","url":null,"abstract":"<p><p>Colonoscopy is fundamental to the diagnosis and treatment of colorectal diseases, with a strong overall safety profile; however, adverse events can still occur and significantly impact patient outcomes and health care utilization. This article summarizes the spectrum of colonoscopy-related complications, including sedation-related events, perforation, bleeding, and other rare but serious complications. It highlights patient-related, procedure-related, and operator-related risk factors, and emphasizes the need for evidence-based preventive strategies, meticulous technique, early recognition, and timely management to minimize morbidity and mortality.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"751-773"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing a Quality Program to Track Colorectal Cancer Screening. 发展一项追踪结直肠癌筛查的高质量项目。
Gastrointestinal Endoscopy Clinics of North America Pub Date : 2026-10-01 Epub Date: 2026-04-08 DOI: 10.1016/j.giec.2026.02.006
James H-E Kang, Max L Goldman, Jeffrey K Lee
{"title":"Developing a Quality Program to Track Colorectal Cancer Screening.","authors":"James H-E Kang, Max L Goldman, Jeffrey K Lee","doi":"10.1016/j.giec.2026.02.006","DOIUrl":"https://doi.org/10.1016/j.giec.2026.02.006","url":null,"abstract":"<p><p>Colorectal cancer screening is a multistep process. Problems at any stage diminish its clinical effectiveness. Common issues include suboptimal return rates for stool-based tests, lack of timely colonoscopy after abnormal stool-based tests, and surveillance recommendations inconsistent with current guidelines. High-quality colonoscopy is also essential. Tracking of screening activities has the potential to enhance program performance, support equitable screening delivery, and strengthen preventive impact at the population level. In this article, we propose features for the ideal tracking system and outline practical considerations concerning design and implementation such as the need for institutional alignment, technical expertise, and multidisciplinary collaboration.</p>","PeriodicalId":35666,"journal":{"name":"Gastrointestinal Endoscopy Clinics of North America","volume":"36 4","pages":"775-790"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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