Blood, Heart and Circulation最新文献

{"title":"Are fat oxidation and cardiorespiratory adaptations impaired during exercise in untreated non-obese severe obstructive sleep apnea patients?","authors":"M. Mendelson, J. Tonini, R. Tamisier, Pépin Jl, P. Lévy, B. Wuyam, P. Flore","doi":"10.15761/BHC.1000152","DOIUrl":"https://doi.org/10.15761/BHC.1000152","url":null,"abstract":"","PeriodicalId":356305,"journal":{"name":"Blood, Heart and Circulation","volume":"193 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115325734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abacavir use and myocardial infarction - Where are we now?","authors":"Satyajit Das","doi":"10.15761/bhc.1000158","DOIUrl":"https://doi.org/10.15761/bhc.1000158","url":null,"abstract":"","PeriodicalId":356305,"journal":{"name":"Blood, Heart and Circulation","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129187554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An intensive training of cardiothoracic surgical skills and simulation course increases procedural knowledge – feedback from fifteen courses","authors":"B. Krishnamoorthy, W. Critchley, Rajen Dinesh Shah, T. Bartely, S. Kendall, M. Lewis, A. Walker, A. Bose","doi":"10.15761/bhc.1000149","DOIUrl":"https://doi.org/10.15761/bhc.1000149","url":null,"abstract":"Background: A lack of incorporated teaching time in the National Health Service leaves surgical trainees and surgical care practitioners lacking confidence during surgery. We implemented a simulation based surgical skills course in cardiothoracic surgery to supplement in-post training. This study aimed to understand the ability of health care professionals and to get their constructive feedback post training. Method: All participants underwent 10 hours of intense cardiothoracic skills training. The participants included are surgical specialist registrars, core surgical trainees and surgical care practitioners. Participants completed pre and post course Likert scale questionnaires assessing their procedural knowledge and learning outcomes. Consultant and senior surgical faculty members taught at the courses in a ratio of almost 2:1 participant to teachers. A variety of cardiothoracic skills were taught using porcine and human cadaverous surgical skills models. All the skills sessions were structured and aligned with their current surgical curriculum. Result: Participants reported low pre-course knowledge of the topics covered in the course (study mean less than 2.07 for all topics). High satisfaction was reported with the content of the course and the organisation and logistics involved. There was a high likelihood of participants recommending the course to colleagues. Conclusion: Pre-course cardiothoracic skills of participants were limited. This clearly identifies that the teaching time spent in the operating theatre is insufficient. All participants felt that these types of cardiothoracic surgical skills courses will increase the chance of improved patient outcomes. It is important to teach trainees with adequate anatomical demonstration and hands on practice outside the theatre settings. This type of training may be useful for other surgical specialities. *Correspondence to: Krishnamoorthy B, Lead Surgical Care Practitioner, Cardiothoracic surgery, Manchester Foundation Trust, Programme Director/ Senior Lecturer at Edgehill University for MSc Surgical Practice, Honorary Research Associate at The University of Manchester, University Hospital of South Manchester NHS Foundation Trust Manchester, UK, Tel: 0044 161 291 2078; Fax: 0044 161 291 5024; E-mail: bhuvaneswari.bibleraaj@mft.nhs.uk","PeriodicalId":356305,"journal":{"name":"Blood, Heart and Circulation","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126796265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benazepril induced acute kidney injury (AKI) in a patient with congestive heart failure (CHF) and moderate chronic kidney disease (CKD): A case report","authors":"Huang Hn, Wang Dn, Zhu Lq, Zhang Jh, Y. Zhang, Tian Dl","doi":"10.15761/BHC.1000151","DOIUrl":"https://doi.org/10.15761/BHC.1000151","url":null,"abstract":"Angiotensin-converting enzyme inhibitors (ACEIs) was demonstrated protective effect for patients with mild to moderate chronic kidney disease (CKD). The ACEIs was usually applied to patients while his serum creatinine (Scr) levels were no more than 3.0 mg/dL. However, it could induce AKI even in the patients with mild to moderate CKD combined with CHF. We report a case of a 62-year-old male with CHF and moderate CKD (SCr: 1.9 mg/dL) who subsequently and transiently develop AKI after he was administrated benazepril 2.5mg/day. Using the Naranjo, benazepril was found to be a probable cause of AKI in the patient. ACEIs, classified as RAAS inhibitors, can induce AKI in some conditions. Attention should be given to benazepril therapy in patients with mild to moderate CKD and CHF. Routine hemodynamic examination and biochemical monitoring was suggested before and during the period of benazepril therapy. *Correspondence to: Zhu LQ, Department of Pharmacy, Tianjin First Central Hospital, Tianjin, China, E-mail: zlq0713@aliyun.com","PeriodicalId":356305,"journal":{"name":"Blood, Heart and Circulation","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130706551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid disorders in HIV patients: what about raised HDL-cholesterol?","authors":"Satyajit Das","doi":"10.15761/bhc.1000150","DOIUrl":"https://doi.org/10.15761/bhc.1000150","url":null,"abstract":"Received: February 08, 2019; Accepted: February 15, 2019; Published: February 18, 2019 The lipid disorders seen in individuals with HIV infection include elevated triglycerides (TG) and total cholesterol (TC), a decrease in high-density lipoprotein cholesterol (HDL-C), and variable effects on low-density lipoprotein (LDL) cholesterol. The exact mechanism is still not clear, and the cause could be multifactorial. The individual contributions of HIV infection, specific antiretroviral agents, host genetics and changes in body composition, all should be considered. However, there has been change in the pattern of dyslipidaemia in HIV patients. This is because most of the newer antiretrovirals have better lipid profile, either they are lipid neutral or causes mild dyslipidaemia. Raised lipids have been observed less often and low HDL-C has been observed less often as well. The Multicentre AIDS Cohort Study (MACS) showed that immediately after HIV infection TC and HDL-C dropped and when treatment is started TC goes back to normal or above normal level and HDL-C comes back to normal or near normal [1]. We wonder whether HDL-C can go above normal or even abnormally high in some patients when they are on treatment for a long time. Raised HDL-C has been observed with nevirapine use but is not known to be associated with an abnormally high level. Abnormally high HDL-C has been noted in HIV patients, but the actual prevalence of abnormally high HDL-C is not reported.","PeriodicalId":356305,"journal":{"name":"Blood, Heart and Circulation","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121949728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}