Indian Journal of Applied Basic Medical Sciences最新文献

{"title":"Analysis And Clinical Study Of Surgical Management And Outcome Of Blunt Abdominal Trauma","authors":"Ravi V. Satasia, S. Chauhan, Aimanhusen M. Payala, Aarsh Panchal, Jaykumar V. Patel, Kuldeep Vanvi","doi":"10.48165/ijabms.2021.233702","DOIUrl":"https://doi.org/10.48165/ijabms.2021.233702","url":null,"abstract":"INTRODUCTION: Trauma during Road Traffic Accident is a major public health problem in all countries. It causes death, disability or both. 50% die immediately at the time of accident. 25% die in golden hour (4–6 hours) of trauma. 25% may die late during treatment period due to sepsis and complications. AIMS AND OBJECTIVES: 1)To study the impact of blunt abdominal trauma on abdominal solid organs like spleen, liver and hollow viscera like stomach and intestine along with various mode of injuries and their different type of management and their outcomes. MATERIALS AND METHODS: This is a prospective study of blunt abdominal injuries during the period from June 2019 to January 2021 in Sheth Lallubhai Gordhandas Municipal General Hospital, Ahmedabad. Number of cases studied is 60. Clinical Data of admitted patient were collected by their detail history after stabilizing the patient, clinical examination with appropriate investigations. RESULTS AND DISSCUSION: In our Study majority of the patients belonged to 21-30 years age group, followed by 31-40 years age group. 46 cases were males, with females accounting for only about 14 cases. 35 patients were operated and 25 patients were selected for non-operative management. Road traffic accident was responsible for 48% of blunt abdominal trauma cases, while fall from heights accounted for 18% of cases and blow with blunt object was responsible for 34% of injuries. Majority of the patients presented with abdominal pain (100%) and abdominal tenderness (76%). Average latent period was between 12-18 hours. Majority of patients (50%) were taken for surgery between 6-10 hours of latent period. Associated extra abdominal injuries were found in 27 cases. Apart from routine investigations, abdomen x ray was done in all patients. Ultrasound of abdomen was done in 53 cases. CT scan was done in 21 cases. CONCLUSION: Propper clinical examination and appropriate investigations helps in management of patient either operative or non-operative which leads successful treatment in these patients. Other associated injuries greatly influence the outcome in morbidity and mortality.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121413147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microvascular complications of diabetes mellitus","authors":"Arti R Goel and Jyoti Vora","doi":"10.48165/IJABMS.2021.23131","DOIUrl":"https://doi.org/10.48165/IJABMS.2021.23131","url":null,"abstract":"INTRODUCTION:Diabetes is a metabolic disease characterized by hyperglycemia, with high morbidity and mortality worldwide. The micro-vascular complications of Diabetes Mellitus, are considered as an important part of hyperglycemia limitations, caused by the increased endothelial permeability and can progress to severe impairments in several organ systems.AIM:To analyse correlation of microvascular complication with period of diabetes mellitus, glycemic control and hypertension.METHOD:A study of 100 patients with DM were included with age ranging from 20 to 80 years.CONCLUSION:Diabetic retinopathy was the most common late complication observed in the study. Diabetic retinopathy, neuropathy and nephropathy all are associated with poor glycemic control. Long duration of DM, with poor glycemic control and the associated hypertension all increase the chances of micro-vascular complications in DM.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125677175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MDCT Evaluation Of Right Iliac Fossa Pathologies With Special Emphasis On Lymph Nodal Characteristics","authors":"Jeel Lathiya and Dipti A. Shah","doi":"10.48165/ijabms.2021.23126","DOIUrl":"https://doi.org/10.48165/ijabms.2021.23126","url":null,"abstract":"Introduction:Right iliac fossa pathologies are one of the common reasons for right iliac fossa pain & patient presentation to the Emergency department. It may be related to either benign or malignant diseases. Radiological imaging plays a pivotal role in the differential diagnosis among these diseases. Lymphatic involvement of diseases helps us to learn about the nature of the disease and predict the way of progression, hence awareness with the normal lymph node radiological appearance and its suspicious criteria by radiologists is a crucial information for treatment preparation and execution.AIMS AND OBJECTIVES:To describe key imaging findings of various right iliac fossa pathologies.To assess the role of characteristics of lymph nodes in various right iliac fossa pathologies.METHODOLOGY:A total of 50 cases clinically suspected & diagnosed of having right iliac fossa pathology by CECT imaging of abdomen, at the department of Radiodiagnosis, AMC MET Medical college, Maninagar, Ahmedabad were included in this study.CECT was carried out on PHILIPS MX 16 slice CT machine after giving oral, rectal & iv contrast and axial, sagittal and coronal images were obtained.RESULTS:In our study, most common pathology found was acute appendicitis (16/50), followed by ileocaecal tuberculosis (12/50) and non-tuberculous infectious enterocolitis (11/50). The other pathologies encountered were epiploic appendagitis (3/50), caecal malignancy (2/50), diverticulitis (2/50), Crohn’s disease (2/50) and lymphoma (1/50).Discussion & CONCLUSION:CE CT images of abdomen are very helpful in diagnosis of various right iliac fossa pathologies. Demonstration of lymph nodal patterns of enhancement and their characteristics can further help in narrowing the diagnosis of right iliac fossa pathologies.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122582730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytological Evaluation Of Enlarged Lymphnodes In Metastatic Disease","authors":"Swati B Parikh, J. Suthar, Biren Parikh, Dipti Panat, Swati K. Panchal","doi":"10.48165/ijabms.2021.23121","DOIUrl":"https://doi.org/10.48165/ijabms.2021.23121","url":null,"abstract":"Introduction: Lymphnodes are common site of metastases for different cancers. Thus, clinical recognition and urgent diagnosis of palpable lymphadenopathy is of paramount importance; specially to differentiate between inflammatory lesions from neoplastic lesions. Fine needle aspiration cytology (FNAC) of the lymph node is a simple diagnostic tool to diagnose suspected and unsuspected lymph node malignancy.Aims–To find out the role of FNAC in the diagnosis of metastatic lesions of lymphnode and whenever possible, for typing of tumor.Material &Method– A total 900 patients, who presented with lymphadenopathy were studied at AMC MET medical College and L.G hospital, Ahmedabad, Gujarat for a period of 2 years. FNAC of enlarged lymphnode was performed and stain with hematoxylin and eosin.Results- Out of total 900 cases studied, 785 were benign and 95 were malignant lesions. Twenty cases were inconclusive. Among the malignant lesions, 80 cases were found to be metastatic lesions. Maximum numbers of metastatic lesions were found in cervical lymphnodes and metastatic squamous cell carcinoma was the most common lesion followed by metastatic adenocarcinoma.Conclusion- FNAC is a simple, rapid, accurate and non-expensive diagnostic technique which can be used for the initial diagnosis of metastatic lymphadenopathy. It can give significant clue to detect the primary site of the tumor in cases with hidden malignancy, who are presented with metastatic lymphadenopathy as an initial sign. Therefore, FNAC is a useful tool in diagnosing metastatic lesion of lymphnodes.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131255575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Result Of Pars Plana Vitrectomy In Post Traumatic Endophthalmitis","authors":"A. Bhatt, Aashka Shah, Sapan Shah, Rutuja Brahmbhatt","doi":"10.48165/ijabms.2021.23124","DOIUrl":"https://doi.org/10.48165/ijabms.2021.23124","url":null,"abstract":"Aim:To evaluate visual outcomes and identify prognostic factors after pars plana vitrectomy (PPV) surgery for traumatic endophthalmitis.Methods:Medical records of 20 patients diagnosed with traumatic endophthalmitis that had undergone pars plana vitrectomy were retrospectively reviewed.Result:20 patients all underwent PPV surgery.50% of them obtained BCVA better than fingers counting (FC). Good final visual prognosis was significantly associated between trauma and PPV treatment.Conclusions:Good visual outcomes can be achieved for most patients who undergo vitreoretinal surgery after open globe trauma.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126434471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laryngoscopy in Neonates and Infants presenting with stridor in tertiary care hospital","authors":"Nipa Dalal, S. Desai, S. Mittal","doi":"10.48165/ijabms.2021.23119","DOIUrl":"https://doi.org/10.48165/ijabms.2021.23119","url":null,"abstract":"INTRODUCTIONNeonatal life involves the readaptation of gas exchange from the intrauterine to extrauterine environment. Stridor in this period reflects a critical airway obstruction which may have been anticipated or wholly unexpected. Many congenital and acquired diseases may cause airway obstruction and respiratory distress in infants.AIMS AND OBJECTIVESTo study the causes of stridor in neonates and infants.Early diagnosis and treatment of the stridor to prevent morbidity and mortality.METHODSThe study was observational study. In this study both qualitative and quantitative approaches were used to collect, analyse and interpret the data. Patients with stridor under age of 1 year who were referred to our department were taken in this study BY DIRECT LARYNGOSCOPYDirect laryngoscopy with macintosh laryngoscope or miller’s blade was done.Results: In our study the most common symptom at presentation was stridor which was present in all 25 cases we have taken.13 cases were presented with difficulty in feeding along with the stridor. This was 2nd most common symptom of presentation.Stridor was associated with fever and cough cold in 13 cases. Change of cry along with stridor observed in 6 cases Result and CONCLUSIONFNPL is gold standard for diagnosis and very useful and safe procedure. Use of better technology and continuous monitoring in NICU/PICU in tertiary care hospital and observation by team of doctors (Pediatrician, ENT Specialist, intensivist etc.) have definitely reduced the rate of morbidity and mortality.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"145 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115786282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Ethics: The Bane of the unethical researcher.","authors":"S. Kadam","doi":"10.48165/ijabms.2021.233701","DOIUrl":"https://doi.org/10.48165/ijabms.2021.233701","url":null,"abstract":"Every human research creates generalizable information which is an integral part of health improvement & understanding of disease. It also causes some risk or inconvenience to research participants. Codes of conduct for physicians have existed since ancient period. Declaration of Helsinki ICMR, Human subjects’ protection; Animal care guidelines etc provide a policy for conduct of research involving research participants in India. The Why & the How in research are vital questions. The ‘Why’ is very clear to define as improvement of public health. What matters more is the ‘How’: while performing it is necessary to adhere to research ethics for promotion of knowledge, truth and avoidance of errors. Research being team work, involves principles of team work such as trust, mutual respect, even handedness, and accountability. Upholding confidentiality, data sharing policies, guidelines of authorship, peer review policies, copyright and patenting policy promotes security of intellectual property and gives confidence for collaborations. Ethical research outlines standard guidelines for institutions and professionals for their behavior towards the specified goals and helps to develop the trust of community further promoting funding.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125627220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy Of Macular Photocoagulation When Given In The Early Or Late Period After Single Intravitreal Bevacizumab Injection In Terms Of Central Foveal Thickness Change And Visual Acuity Gain","authors":"Aaska Sapan Shah, Naimish Haribhai Mahaliya, Sapan Shah, J. Joshi","doi":"10.48165/ijabms.2021.23122","DOIUrl":"https://doi.org/10.48165/ijabms.2021.23122","url":null,"abstract":"AIM: To find out the efficacy of macular photocoagulation when given in the early or late period after single intravitreal bevacizumab injection in terms of central foveal thickness change and visual acuity gain.METHODS:40 patient eyes were studied and they were divided into groups based on sex, age, hba1c levels, severity of disease and treatment received over the period of 6months.RESULT: patients receiving deferred macular photocoagulation after a single intravitreal injection of bevacizumab had better outcomes regarding reduction of central foveal thickness and improvement in visual acuity at the end of 6-month observation period compared to those patients receiving prompt macular photocoagulation.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"215 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122404659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Profile And Commodities In Obese Patient","authors":"Kaushika S Chaudhary, Sangeeta K. Rathod, Vikas Nayi, Archita Patel","doi":"10.48165/ijabms.2021.23113","DOIUrl":"https://doi.org/10.48165/ijabms.2021.23113","url":null,"abstract":"Although the terms overweight and obesity are often used interchangeably, overweight refers to an excess of body weight compared with height; obesity refers to an excess of body fat in the form of adipose tissue(adiposity). The study discusses CLINICAL PROFILE AND COMMODITIES IN OBESE PATIENT in our setup in Ahmedabad in one urban hospital.AIMS:To study clinical and laboratory profile of patients with obesity.To asses’ comorbidities in obese patientTo find the age group and gender in which it is common.Material and Methods:A cross sectional study was conducted in L G Hospital Maninagar Ahmedabad in January to march2019. Study included both outdoor and indoor patients with BMI >=30. In our study, total 200 patients wereanalysed for comorbidities. BMI was calculated using the expression = Weight (kilograms)/Height2(meters). The cut off point for calculation of overweight/preobesity taken was ≥25 kg/m2 and for obesity was≥30 kg/m2 as per the WHO 2000 guidelines. The blood pressure was recorded as per standard protocol andmean of three readings was recorded.Results:SBP, DBP, TSH and RBS were significantly elevated in obese persons. It may be concluded that a fairly high prevalence of obesity in Ahmedabad area & associated comorbidities is also more prevalent related to this. Increase in body weight may also be due to change in life style factors like fat rich food, more usage of alcoholsmoking, increased energy intake and low energy output due to less involvement of in physical activity.Discussion and CONCLUSION:The result shows higher trends of hypertension, DM2, hypothyroidism and dylipidemia with increase in BMI. Measure regarding reducing BMI reduce new incidence of such non communicable disease.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132049996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative study of external dacryocystorhinostomy versus endonasal Dacryocystorhinostomy","authors":"A. Misra","doi":"10.48165/ijabms.2021.23123","DOIUrl":"https://doi.org/10.48165/ijabms.2021.23123","url":null,"abstract":"Background: Surgical treatment of dacryocystitis dates back to nearly 2000 years ago described as creating an artificial passageway into the nose using hot cautery to puncture through the lacrimal bone. Better understanding of lacrimal physiology and nasal and lacrimal anatomy through the centuries led to development of a procedure that would resemble a modern external DCR surgery in the 18th century. Intranasal approach operations had also been described in the 20th century. Advancements in methods of DCR surgery have been procured in view of cosmesis, amount of bleeding, duration of surgery, and outcome of the procedure.Aim/Objective: The aim of this study is to compare endonasal DCR and external DCR in the following prospect Methods: This was a hospital based, interventional, prospective, non-randomized study of a total of 100 randomly selected patients of chronic dacryocystitis from OPD. 50 patients underwent external DCR and 50 patients underwent endonasal DCR. Young patients with good nasal space and without any nasal abnormality were operated for endonasal DCR, and old patients or those with nasal abnormalities were operated for external DCR. Preoperative assessment included an ENT evaluation, blood pressure, sac syringing, and blood investigations. Surgery was performed and post-operative assessments were conducted in the aspects of complications of surgery, intraoperative bleeding, surgical time and outcome of surgery.Results: From a total of 100 patients, 59% were females of which 54% were operated by endonasal DCR, with 30% of the population of total persons operated aging 60-70 years. There is more prevalence of dacryocystitis in females and in old aged patients in this study due to more chances of lacrimal pump failure in old age, and hormonal factors, smaller skull size and application on local cosmesis for females. Punctum patency after 6 months comparing endonasal and external DCR surgery using chi square formula proved a P value of 0.0008 which is highly significant showing that external DCR has significantly higher success rate than endonasal DCR. In the aspect of complications, the study proved a greater chance of recurrence of epiphora in external DCR, also the presence of a skin scar and wound dehiscence persists as a complication in external DCR due to the external skin incision which is not made in endonasal DCR.Conclusion: DCR is the treatment of choice for nasolacrimal duct obstruction, and it can be performed by external or endoscopic approach. Both approaches have minimal complications and comparable surgical outcome, hence the choice of surgery should depend upon the patient’s preference, availability of resources and surgeon’s expertise.","PeriodicalId":354981,"journal":{"name":"Indian Journal of Applied Basic Medical Sciences","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116421654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}