The Journal of rheumatology. Supplement最新文献_第3页

The impact of communicative and critical health literacy on trust in physicians among patients with systemic lupus erythematosus: the TRUMP2-SLE project 沟通和关键健康素养对系统性红斑狼疮患者对医生信任的影响:TRUMP2-SLE项目

The Journal of rheumatology. Supplement Pub Date : 2022-05-16 DOI: 10.1101/2022.05.13.22275070

N. Oguro, N. Yajima, Y. Miyawaki, R. Yoshimi, Y. Shimojima, K. Sada, K. Hayashi, K. Shidahara, N. Sakurai, C. Hidekawa, D. Kishida, T. Ichikawa, Y. Ishikawa, N. Kurita

{"title":"The impact of communicative and critical health literacy on trust in physicians among patients with systemic lupus erythematosus: the TRUMP2-SLE project","authors":"N. Oguro, N. Yajima, Y. Miyawaki, R. Yoshimi, Y. Shimojima, K. Sada, K. Hayashi, K. Shidahara, N. Sakurai, C. Hidekawa, D. Kishida, T. Ichikawa, Y. Ishikawa, N. Kurita","doi":"10.1101/2022.05.13.22275070","DOIUrl":"https://doi.org/10.1101/2022.05.13.22275070","url":null,"abstract":"Objectives: Accessing the Internet has increased the gap in patient health literacy (HL), impacting patient-doctor trust. We examined how trust in physicians is affected by functional HL (the ability to read and write) and by broader concepts of HL, including communicative HL (the ability to extract information from communication to use) and critical HL (the ability to analyze and use information) among patients with systemic lupus erythematosus (SLE). Methods: This cross-sectional study enrolled 362 SLE patients at five academic centers between June 2020 and August 2021. The 14-item Functional Communicative Critical Health Literacy Scale assessed the three dimensions of HL (range: 1-4 points). Outcomes were trust in one's physician and physicians generally using the 5-item Wake Forest Physician Trust Scale (range: 0-100 points). General linear models adjusted for age, sex, education, income, disease activity, disease duration, depression, and time using the Internet. Results: Trust in one's physician increased with higher functional and communicative HL (per 1-pt increase, 3.21 [95%CI 0.61, 5.81], 5.8 [95%CI 1.96, 9.63]). Trust in physicians in general increased with higher communicative HL and decreased with higher critical HL (per 1-pt increase, 7.01 [95%CI 2.27, 11.76], -6.83 [95%CI -11.67, -1.99]). Longer Internet use was associated with both higher communicative and critical HL. Conclusions: Our findings suggest that rheumatologists can help patients build trust by encouraging dialogue about their health issues with their doctors and family members, rather than trying to improve their ability to discern health information.","PeriodicalId":35278,"journal":{"name":"The Journal of rheumatology. Supplement","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85647527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Beyond Empowerment in Rheumatology Care 风湿病护理中的超越授权

The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI: 10.3899/jrheum.220348

A. D. de Lara, I. Peláez-Ballestas

引用次数: 2

Some Key Issues Relating to the Reporting and Interpretation of Time-to-Event Data 与事件时间数据的报告和解释有关的一些关键问题

The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI: 10.3899/jrheum.220053

I. M. Schou

引用次数: 0

Personally Generated Quality of Life Outcomes in Adults With Juvenile Idiopathic Arthritis 青少年特发性关节炎成人患者个人产生的生活质量结果

The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI: 10.3899/jrheum.211245

A. Tollisen, A. Selvaag, A. Aasland, T. Ingebrigtsen, J. Sagen, A. Lerdal, B. Flatø

{"title":"Personally Generated Quality of Life Outcomes in Adults With Juvenile Idiopathic Arthritis","authors":"A. Tollisen, A. Selvaag, A. Aasland, T. Ingebrigtsen, J. Sagen, A. Lerdal, B. Flatø","doi":"10.3899/jrheum.211245","DOIUrl":"https://doi.org/10.3899/jrheum.211245","url":null,"abstract":"Objective To explore quality of life (QOL) using the individualized Patient Generated Index (PGI) in young adults who were diagnosed with juvenile idiopathic arthritis (JIA) in childhood, and to examine associations between PGI ratings and standardized health-related outcome measures. Methods Patients (N = 79, mean age 25.1 [SD 4.2] yrs, 72% female) completed the PGI and the standardized measures: Health Assessment Questionnaire–Disability Index, 12-item Short Form Health Survey (SF-12; physical and mental health-related QOL [HRQOL]), Brief Pain Inventory (pain severity and interference), 5-item Hopkins Symptom Checklist, and visual analog scale for fatigue. Information on morning stiffness, medications, and demographics was also collected. Patients were compared to 79 matched controls. Results The most frequently nominated areas of importance for patients’ personally generated QOL (assessed by PGI) were physical activity (n = 38, 48%), work/school (n = 31, 39%), fatigue (n = 29, 37%) and self-image (n = 26, 33%). Nomination of physical activity was associated with older age, morning stiffness, and more pain interference. Nomination of fatigue was associated with current use of disease-modifying antirheumatic drugs, whereas nomination of self-image was associated with polyarticular course JIA and pain interference. Nomination of work/school was not associated with other factors. Higher PGI scores (indicating better QOL) correlated positively with all SF-12 subscales except role emotional, and negatively with disability, pain severity, pain interference, and morning stiffness. Compared to controls, patients had more pain, poorer physical HRQOL, and less participation in full-time work or school. Conclusion Physical activity, work/school, fatigue, and self-image were frequently nominated areas affecting QOL in young adults with JIA. The PGI included aspects of QOL not covered in standardized measures.","PeriodicalId":35278,"journal":{"name":"The Journal of rheumatology. Supplement","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80283477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Spondyloarthritis Among Patients With Uveitis: Can We Improve Referral Pathways? 葡萄膜炎患者的脊柱炎:我们能改善转诊途径吗?

The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI: 10.3899/jrheum.220263

L. Eder

引用次数: 0

Impact of Axial Spondyloarthritis on Quality of Life: Results From the European Map of Axial Spondyloarthritis (EMAS) Study in France 中轴性脊柱炎对生活质量的影响:来自法国中轴性脊柱炎欧洲地图(EMAS)研究的结果

The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI: 10.3899/jrheum.210864

J. Kędra, P. Claudepierre, R. Flipo, M. Garrido-Cumbrera, F. Alliot-Launois, E. Desfleurs, L. Grange, L. Gossec

引用次数: 0

Vasculitis: What Have We Learned in the Last 50 Years? 血管炎:过去50年我们学到了什么?

The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI: 10.3899/jrheum.220207

S. Carette

引用次数: 0

Management of Calcinosis Cutis in Rheumatic Diseases 风湿病患者皮肤钙质沉着症的治疗

The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI: 10.3899/jrheum.211393

Hadiya Elahmar, B. Feldman, S. Johnson

引用次数: 9

Dr. Griffiths et al reply Griffiths博士等人回答

The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI: 10.3899/jrheum.220120

J. Leadbetter, H. Griffiths

引用次数: 0

Association of M2 Macrophages, Th2, and B Cells With Pathomechanism in Microscopic Polyangiitis Complicated by Interstitial Lung Disease M2巨噬细胞、Th2和B细胞与显微多血管炎合并间质性肺疾病的病理机制的关联

The Journal of rheumatology. Supplement Pub Date : 2022-05-02 DOI: 10.3899/jrheum.220123

S. Matsuda, T. Kotani, H. Kuwabara, Takayasu Suzuka, Takao Kiboshi, Y. Wada, T. Ishida, Youhei Fujiki, Hideyuki Shiba, K. Hata, T. Shoda, Y. Hirose, T. Takeuchi

{"title":"Association of M2 Macrophages, Th2, and B Cells With Pathomechanism in Microscopic Polyangiitis Complicated by Interstitial Lung Disease","authors":"S. Matsuda, T. Kotani, H. Kuwabara, Takayasu Suzuka, Takao Kiboshi, Y. Wada, T. Ishida, Youhei Fujiki, Hideyuki Shiba, K. Hata, T. Shoda, Y. Hirose, T. Takeuchi","doi":"10.3899/jrheum.220123","DOIUrl":"https://doi.org/10.3899/jrheum.220123","url":null,"abstract":"Objective To address the pathomechanism of microscopic polyangiitis (MPA) complicated by interstitial lung disease (ILD) using serum biomarker profile and pulmonary histopathology. Methods Serum biomarkers from patients with MPA-ILD (n = 32), MPA without ILD (n = 17), and healthy controls (n = 10) were examined. Based on the biomarker profiles, principal component analysis (PCA) and cluster analysis were performed to classify patients with MPA-ILD into subgroups. Clinical characteristics and prognosis were assessed for each subgroup. Two lung biopsies were examined following H&E staining and immunostaining. Results T cell and macrophage polarization was skewed toward the T helper (Th) 2 cells and M2 macrophages in the MPA-ILD group relative to that in MPA without ILD group. The PCA allowed classification of the 19 biomarker profiles into 3 groups: (1) B cell– and neutrophil-related cytokines, vascular angiogenesis-related factors, extracellular matrix-producing factors; (2) Th1-driven cytokines, M1 macrophage-driven cytokines, and Th2-driven cytokines; and (3) M2 macrophage-induced and driven cytokines. The cluster analysis stratified the patients with MPA-ILD into clinically fibrotic-dominant (CFD) and clinically inflammatory-dominant (CID) groups. Notably, severe infections were significantly higher in the CFD group than in the CID group. Immunohistochemical staining demonstrated intense CXC motif chemokine ligand 13 staining in B cells and Th2 cells in the interstitium of the lungs of patients with MPA-ILD. Conclusion. The activation of M2 macrophages, Th2 cells, and B cells plays a key role in the pathomechanism of MPA-ILD. Classification of MPA-ILD based on serum biomarker profile would be useful in predicting the disease activity and the complications of severe infection in MPA-ILD.","PeriodicalId":35278,"journal":{"name":"The Journal of rheumatology. Supplement","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90691548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1