Hospital practice (1995)最新文献

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Clinical outcome of pre-operative blood transfusion for sickle cell disease patients in post-operative complications. 镰状细胞病患者术前输血治疗术后并发症的临床效果。
Hospital practice (1995) Pub Date : 2022-12-01 Epub Date: 2022-09-06 DOI: 10.1080/21548331.2022.2121574
Abrar J Alwaheed, Safi G Alqatari, Dania M AlKhafaji, Reem J Al Argan, Osama A Al Sultan, Reem S AlSulaiman, Faisal S AlShahrani, Faisal A Alghamdi, Abdullah M Alkhudair, Abdulrahman A Alghamdi
{"title":"Clinical outcome of pre-operative blood transfusion for sickle cell disease patients in post-operative complications.","authors":"Abrar J Alwaheed,&nbsp;Safi G Alqatari,&nbsp;Dania M AlKhafaji,&nbsp;Reem J Al Argan,&nbsp;Osama A Al Sultan,&nbsp;Reem S AlSulaiman,&nbsp;Faisal S AlShahrani,&nbsp;Faisal A Alghamdi,&nbsp;Abdullah M Alkhudair,&nbsp;Abdulrahman A Alghamdi","doi":"10.1080/21548331.2022.2121574","DOIUrl":"https://doi.org/10.1080/21548331.2022.2121574","url":null,"abstract":"<p><strong>Background: </strong>Preoperative blood transfusion for patients with sickle cell disease is a debatable topic and it can be lifesaving. Sickle cell disease patients are at high risk for vaso-occlusive crisis due to the large concentration of sickle hemoglobin (HgbS) in their blood. Despite the current extensive research into this disease, there is still no consensus over whether blood transfusion is a preferable preoperative modality among patients undergoing elective surgical procedures.</p><p><strong>Method: </strong>A retrospective observational study, which enrolled 204 patients with Sickle cell disease who underwent surgery at King Fahad Hospital of the University (KFHU) over the last five years. The primary objective was to determine whether there is evidence that preoperative blood transfusion for SCD patients undergoing surgical procedures will reduce postoperative complications related to SCD.</p><p><strong>Results: </strong>A total of 204 patients were included, of which 30% had preoperative blood transfusion. Majority of patient 44% had undergone cholecystectomy. On multivariate logistic regression analysis, patients who did not undergo blood transfusion had significantly higher risk to develop post-operative SCD complications (OR = 3.07, P value = 0.002). In addition, they had significantly prolonged hospitalization (OR = 2.22, P value = 0.08). In contrast, patients who received blood transfusion had lower risk for developing post-operative SCD-related complications (OR = 1.87, P value = 0.29), and decrease in the duration of hospitalization by (OR = 0.49, P value = 0.045).</p><p><strong>Conclusion: </strong>Our study showed that patients who had not undergone preoperative blood transfusion had higher risk to develop postoperative complications and prolonged hospital stay compared to those who underwent blood transfusion.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"361-367"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The inpatient experience of emerging adults in the United States. 美国新生成人的住院经历。
Hospital practice (1995) Pub Date : 2022-12-01 Epub Date: 2022-10-14 DOI: 10.1080/21548331.2022.2129176
Nicole Oakman, Daniel Driver, Michelle Berlacher, Maryam Warsi, Eugene S Chu
{"title":"The inpatient experience of emerging adults in the United States.","authors":"Nicole Oakman,&nbsp;Daniel Driver,&nbsp;Michelle Berlacher,&nbsp;Maryam Warsi,&nbsp;Eugene S Chu","doi":"10.1080/21548331.2022.2129176","DOIUrl":"https://doi.org/10.1080/21548331.2022.2129176","url":null,"abstract":"<p><strong>Objectives: </strong>Emerging adults transitioning from pediatric to adult care experience worse outcomes including increased mortality. Improved patient experience (PEX) correlates with decreased inpatient mortality and better adherence to quality guidelines. We aimed to evaluate trends in the PEX of inpatients aged 14-29 years in the United States (US).</p><p><strong>Methods: </strong>We performed a retrospective cohort study using a national, de-identified PEX survey obtained from hospitalized patients aged 14-29 years between 2017 and 2019. We described and compared survey responses across 10 domains. Composite mean scores for each health facility were converted to percentile rankings, which were then compared by age group to determine differences in percentile ranking (ΔPR).</p><p><strong>Results: </strong>We evaluated the results of 174,174 PEX surveys across a national sample of 1519 US hospitals. The PEX percentile rankings for ages 18-21 were lower than ages 14-17 in almost every domain including experience with nurses (ΔPR = 43.4, p < 0.001), physicians (ΔPR = 31.1, p < 0.001), treatment (ΔPR = 12.3, p < 0.001), and overall experience (ΔPR = 26.5, p < 0.001). Similarly, 22-25-year-olds reported a worse PEX across nearly all domains when compared to 26-29-year-olds.</p><p><strong>Conclusion: </strong>In a national sample of PEX surveys, hospitalized emerging adults aged 18-25 reported worse PEX when compared to both older children and established adults. These lower ratings were most strongly attributed to people, processes, and relationships as opposed to differences in the hospital environment. By ages 26-29, PEX returned to levels similar to those reported by ages 14-17. These results suggest that further investigation to elucidate the unique needs of hospitalized emerging adults may be warranted.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"400-406"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33480961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of a medical intensive care team in the emergency department of a tertiary medical center in the USA. 在美国三级医疗中心急诊科实施医疗重症监护小组。
Hospital practice (1995) Pub Date : 2022-12-01 Epub Date: 2022-09-20 DOI: 10.1080/21548331.2022.2126255
Erin Tuttle, Xuan Wang, Ariel Modrykamien
{"title":"Implementation of a medical intensive care team in the emergency department of a tertiary medical center in the USA.","authors":"Erin Tuttle,&nbsp;Xuan Wang,&nbsp;Ariel Modrykamien","doi":"10.1080/21548331.2022.2126255","DOIUrl":"https://doi.org/10.1080/21548331.2022.2126255","url":null,"abstract":"<p><strong>Objective: </strong>Critically ill patients boarding in the ED have higher mortality rates. Several strategies have been implemented to deliver care to boarding patients. Our institution opted for a strategy consisting on deploying an Intensive Care team in the ED. This article reports outcomes before-and-after implementation of that team.</p><p><strong>Methods: </strong>On November 2020, a Medical Intensive Care Team was deployed in the ED. The team performed consultations for ICU patients boarding in the ED. A retrospective analysis of critically ill patients arriving to the ED before-and-after team implementation was performed. Outcome data were reviewed. Direct hospitalization costs per patient, and direct costs per department were assessed. Wilcoxon rank sum and Chisq-test were utilized to compare differences pre- and post-implementation. Multivariate analyses to model outcomes toward pre- and post-implementation and other variables were performed.</p><p><strong>Results: </strong>1,828 and 3,272 patients were included in the pre- and post-intervention groups. ICU LOS (days) pre- and post-intervention were 3 (1,6) and 3 (1,6), respectively (p = 0.41). ICU readmission rates were 6.7% pre-intervention and 7.4% post-intervention (p = 0.37). Total direct costs were US$ 19,928 (11,006, 37,815) and US$ 15,795 (9016, 28,993), respectively (p < 0.01). Multivariate analysis showed no association between team deployment and ICU LOS or readmission. However, there was association between its implementation and hospitalization cost reduction per patient of US$ 7,171.</p><p><strong>Conclusion: </strong>The implementation of a Medical Intensive Care team in the ED is not associated with a reduction of ICU LOS or ICU readmission. Nevertheless, its implementation is associated with a reduction of hospitalization costs.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"387-392"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40358019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-discharge early assessment with remote video link (PEARL) initiative for patients discharged from hospital medicine services. 采用远程视频链接(PEARL)对出院患者进行出院后早期评估的举措。
Hospital practice (1995) Pub Date : 2022-12-01 Epub Date: 2022-09-23 DOI: 10.1080/21548331.2022.2125726
Sagar B Dugani, Shangwe A Kiliaki, Megan L Nielsen, Trevor J Coons, Karen M Fischer, Riddhi S Parikh, Sandeep R Pagali, Anne Liwonjo, Darrell R Schroeder, Ivana T Croghan, M Caroline Burton
{"title":"Post-discharge early assessment with remote video link (PEARL) initiative for patients discharged from hospital medicine services.","authors":"Sagar B Dugani, Shangwe A Kiliaki, Megan L Nielsen, Trevor J Coons, Karen M Fischer, Riddhi S Parikh, Sandeep R Pagali, Anne Liwonjo, Darrell R Schroeder, Ivana T Croghan, M Caroline Burton","doi":"10.1080/21548331.2022.2125726","DOIUrl":"10.1080/21548331.2022.2125726","url":null,"abstract":"<p><strong>Objectives: </strong>The COVID-19 pandemic impacted the availability and accessibility of outpatient care following hospital discharge. Hospitalists (physicians) and hospital medicine advanced practice providers (HM-APPs) coordinate discharge care of hospitalized patients; however, it is unknown if they can deliver post-discharge virtual care and overcome barriers to outpatient care. The objective was to develop and provide post-discharge virtual care for patients discharged from hospital medicine services.</p><p><strong>Methods: </strong>We developed the Post-discharge Early Assessment with Remote video Link (PEARL) initiative for HM-APPs to conduct a post-discharge video visit (to review recommendations) and telephone follow-up (to evaluate adherence) with patients 2-6 days following hospital discharge. Participants included patients discharged from hospital medicine services at an institution's hospitals in Rochester (May 2020-August 2020) and Austin (November 2020-February 2021) in Minnesota, US. HM-APPs also interviewed patients about their experience with the video visit and completed a survey on their experience with PEARL.</p><p><strong>Results: </strong>Of 386 eligible patients, 61.4% were enrolled (n = 237/386) including 48.1% women (n = 114/237). In patients with complete video visit and telephone follow-up (n = 141/237), most were prescribed new medications (83.7%) and took them as prescribed (93.2%). Among five classes of chronic medications, patient-reported adherence ranged from 59.2% (narcotics) to 91.5% (anti-hypertensives). Patient-reported self-management of 12 discharge recommendations ranged from 40% (smoking cessation) to 100% (checking rashes). Patients reported benefit from the video visit (agree: 77.3%) with an equivocal preference for video visits over clinic visits. Among HM-APPs who responded to the survey (88.2%; n = 15/17), 73.3% reported benefit from visual contact with patients but were uncertain if video visits would reduce emergency department visits.</p><p><strong>Conclusion: </strong>In this novel initiative, HM-APPs used video visits to provide care beyond their hospital role, reinforce discharge recommendations for patients, and reduce barriers to outpatient care. The effect of this initiative is under evaluation in a randomized controlled trial.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"379-386"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9691619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40359781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Factors affecting hospital services overutilization and reductive strategies in Iran: a qualitative study to explore experts' views. 伊朗医院服务过度利用的影响因素和减少策略:一项探讨专家观点的定性研究。
Hospital practice (1995) Pub Date : 2022-12-01 Epub Date: 2022-10-19 DOI: 10.1080/21548331.2022.2134679
Leila Doshmangir, Hossein Jabbari, Morteza Arab-Zozani, Mohammad Naghavi-Behzad, Zeinab Abedi, Hakimeh Mostafavi
{"title":"Factors affecting hospital services overutilization and reductive strategies in Iran: a qualitative study to explore experts' views.","authors":"Leila Doshmangir,&nbsp;Hossein Jabbari,&nbsp;Morteza Arab-Zozani,&nbsp;Mohammad Naghavi-Behzad,&nbsp;Zeinab Abedi,&nbsp;Hakimeh Mostafavi","doi":"10.1080/21548331.2022.2134679","DOIUrl":"https://doi.org/10.1080/21548331.2022.2134679","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the viewpoints of the main stakeholders of the Iranian healthcare system about the overutilization of hospital services and strategies to eliminate or reduce it in Iran.</p><p><strong>Methods: </strong>This is a qualitative study and thematic data analysis using face-to-face semi-structured interviews and Focus Group Discussions (FGDs). We conducted eight interviewers and two FGDs with hospital stakeholders including faculty members, insurance organizations' authorities, experienced hospital administrative staff, hospital managers, and health-care providers.</p><p><strong>Results: </strong>The factors leading to the overutilization of hospital services were categorized into four main themes including site of service, quality, supplier push, and demand pull. Strategies for eliminating or reducing the overutilization of hospital services are also identified based on the influential factors.</p><p><strong>Conclusion: </strong>Addressing overutilization of hospital services in the health system and adherence to policies for reducing or eliminating overutilization is a way to make preventive strategies to overcome overutilization. Developing a national plan to integrate utilization management into health system programs is a strategy to combat overutilization in various levels of the health system including hospital setting.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"416-424"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33502114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New lung cancer diagnosis after emergency department presentation in a tertiary hospital: patient characteristics and outcomes. 三级医院急诊科就诊后的肺癌新诊断:患者特征和结果。
Hospital practice (1995) Pub Date : 2022-12-01 Epub Date: 2022-09-08 DOI: 10.1080/21548331.2022.2121573
Navin Niranjan, Krishna Bajee Sriram
{"title":"New lung cancer diagnosis after emergency department presentation in a tertiary hospital: patient characteristics and outcomes.","authors":"Navin Niranjan,&nbsp;Krishna Bajee Sriram","doi":"10.1080/21548331.2022.2121573","DOIUrl":"https://doi.org/10.1080/21548331.2022.2121573","url":null,"abstract":"<p><strong>Objectives: </strong>Currently, there are limited data available about patients who are diagnosed with lung cancer following an emergency department (ED) visit. This study sought to define the demographics, symptoms profile, staging, and prognosis of this cohort of patients.</p><p><strong>Methods: </strong>We conducted a retrospective study of patients diagnosed with a primary lung malignancy at a lung cancer multidisciplinary meeting between January 2018 and January 2020. Medical records were reviewed to collect data around demographics, presenting symptoms, investigations, admission, cancer stage, and mortality.</p><p><strong>Results: </strong>During the study period, 890 patients were diagnosed with a primary lung malignancy of which 209 (23.5%) presented to ED prompting diagnostic work-up. Of these 209 patients, 89% were hospitalized for a median duration of 6 days. Also, 104 (50%) were female and the average age of the cohort was 70 years. Dyspnea (38%) was the most common presenting symptom. Radiological staging and tissue biopsy were performed as an outpatient procedure in 46% and 41% of patients, respectively. A total of 188 patients had non-small cell lung cancer of whom 68% had ztage IV disease. A total of 53 (25%) patients died within 3 months of ED presentation. These patients were older with more advanced disease compared to patients who were alive at 3 months.</p><p><strong>Conclusion: </strong>Emergent diagnosed patients are a significant proportion of the lung cancer population, presenting with advanced stage disease and increased short-term mortality. Future research should be directed at interventions, such as lung cancer screening program and/or community education, to reduce the need for patients to present to the ED with disabling lung cancer symptoms.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"356-360"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40345271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Increasing importance of breast cancer in Nepal. 乳腺癌在尼泊尔日益受到重视。
Hospital practice (1995) Pub Date : 2022-12-01 Epub Date: 2022-09-21 DOI: 10.1080/21548331.2022.2125724
Ruqaiyyah Siddiqui, Ajnish Ghimire, Jibran Sualeh Muhammad, Naveed Ahmed Khan
{"title":"Increasing importance of breast cancer in Nepal.","authors":"Ruqaiyyah Siddiqui,&nbsp;Ajnish Ghimire,&nbsp;Jibran Sualeh Muhammad,&nbsp;Naveed Ahmed Khan","doi":"10.1080/21548331.2022.2125724","DOIUrl":"https://doi.org/10.1080/21548331.2022.2125724","url":null,"abstract":"<p><p>Recently, breast cancer cases in Nepal are on the rise, accounting for approximately 16% of all cancer cases, making it the second most common malignancy. Given the dependence of the Nepalese on agriculture, the rampant use of pesticides as well as the presence of arsenic in water supplies might be contributing to this huge rise in cancer cases. Herein, we provide a brief overview of the status of breast cancer, its burden, risk factors, screening and modes of treatment in Nepal.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"347-355"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40359069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'COVID-Somnia' in healthcare workers during the pandemic. 大流行期间医护人员的“covid - sleep”。
Hospital practice (1995) Pub Date : 2022-10-01 Epub Date: 2022-07-22 DOI: 10.1080/21548331.2022.2102777
Neslihan Özçelik, Hasan Veysel Kesin, Gokhan Telatar, Songül Özyurt, Bilge Yılmaz Kara, Aziz Gümüş, Çiçek Hocaoğlu, Ünal Şahin
{"title":"'COVID-Somnia' in healthcare workers during the pandemic.","authors":"Neslihan Özçelik,&nbsp;Hasan Veysel Kesin,&nbsp;Gokhan Telatar,&nbsp;Songül Özyurt,&nbsp;Bilge Yılmaz Kara,&nbsp;Aziz Gümüş,&nbsp;Çiçek Hocaoğlu,&nbsp;Ünal Şahin","doi":"10.1080/21548331.2022.2102777","DOIUrl":"https://doi.org/10.1080/21548331.2022.2102777","url":null,"abstract":"<p><strong>Objectives: </strong>Sleep disorders associated with COVID-19 pandemic are termed as 'COVID-somnia.' In this study, we sought to assess the prevalence of COVID-somnia in healthcare workers, establish the factors that trigger this condition, and to investigate its relationship with anxiety and depression symptoms.</p><p><strong>Methods: </strong>This cross-sectional study was conducted between April 2021 and June 2021, and it included healthcare workers who served during the pandemic. Participants' demographic data, Beck Depression and Anxiety Inventories, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and Insomnia Severity Index (ISI) were used, and the results were statistically analyzed. Multiple analyses of factors affecting ESS and ISI scores were evaluated using binary logistic regression model and PSQI score were analyzed using a multiple linear regression model.</p><p><strong>Results: </strong>A total of 1,111 healthcare workers who served during the pandemic voluntarily enrolled to the study. The mean age was 37.3 ± 8.48 years, and 63.5% were females. Our study showed that the healthcare workers, evaluated with the PSQI, experienced a deterioration of sleep quality. Primary factors affecting this are working on the front line, the presence of chronic diseases, depression, and anxiety. Regression analyses identified depression and anxiety as the common factors affecting ESS, ISI, and PSQI scores.</p><p><strong>Conclusion: </strong>Raising awareness regarding COVID-somnia among healthcare workers, who play a leading role in curbing the pandemic, would reduce sleep disturbances, depression, and anxiety. It would also contribute to the planning and implementation of preventive and therapeutic mental health programs with a multidisciplinary approach.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"273-281"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40525065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Posterior pole analysis and ganglion cell layer measurements in Alzheimer's disease. 阿尔茨海默病的后极分析和神经节细胞层测量。
Hospital practice (1995) Pub Date : 2022-10-01 Epub Date: 2022-08-02 DOI: 10.1080/21548331.2022.2107794
Yasemin Un, Funda Alpaslan, Nejla Tukenmez Dikmen, Murat Sonmez
{"title":"Posterior pole analysis and ganglion cell layer measurements in Alzheimer's disease.","authors":"Yasemin Un,&nbsp;Funda Alpaslan,&nbsp;Nejla Tukenmez Dikmen,&nbsp;Murat Sonmez","doi":"10.1080/21548331.2022.2107794","DOIUrl":"https://doi.org/10.1080/21548331.2022.2107794","url":null,"abstract":"<p><strong>Aim: </strong>To compare posterior pole analysis and ganglion cell layer (GCL) of patients with Alzheimer's disease (AD) and controls.</p><p><strong>Method: </strong>Patients diagnosed with mild and moderate AD included in the study. Posterior pole analysis and GCL measurements were investigated by dividing the macula into superior and inferior hemifields and 5 corresponding zones.</p><p><strong>Results: </strong>There were no significant differences between groups for retinal thickness measurements in any retinal zone. GCL measurements showed lower measurements in moderate AD group for GCL thickness in the superior zone 2 (p:0.025) and inferior zone 2 (p = 0.048) compared to mild AD and controls. A moderate AD status was found to cause a decrease of 5.349 µm in the GCL-SZ2 value [p:0.037].</p><p><strong>Conclusion: </strong>GCL measurements in the moderate AD group show significant thinning in superior and inferior Zone 2, which may be a biomarker for AD.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"282-288"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40641060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Management of opioid withdrawal and initiation of medications for opioid use disorder in the hospital setting. 阿片类药物戒断和阿片类药物使用障碍在医院的管理。
Hospital practice (1995) Pub Date : 2022-10-01 Epub Date: 2022-07-22 DOI: 10.1080/21548331.2022.2102776
Nico Carswell, Giselle Angermaier, Christopher Castaneda, Fabrizzio Delgado
{"title":"Management of opioid withdrawal and initiation of medications for opioid use disorder in the hospital setting.","authors":"Nico Carswell,&nbsp;Giselle Angermaier,&nbsp;Christopher Castaneda,&nbsp;Fabrizzio Delgado","doi":"10.1080/21548331.2022.2102776","DOIUrl":"https://doi.org/10.1080/21548331.2022.2102776","url":null,"abstract":"<p><strong>Introduction: </strong>Opioid use disorder (OUD) has become increasingly prevalent among hospitalized patients in the United States and globally. As its prevalence increases, this provides a valuable opportunity for clinicians in the hospital setting to engage and initiate management and treatment of OUD.</p><p><strong>Purpose: </strong>This article aims to provide hospitalists and other clinicians working in the hospital with a narrative review of the management of opioid withdrawal and the initiation of medications for opioid use disorder (MOUD) in the hospital and provide an update on a novel low dose approach to buprenorphine induction (also commonly referred to as the 'microinduction' method).</p><p><strong>Methods: </strong>Authors performed a narrative review of the literature.</p><p><strong>Results: </strong>Management can initially include treating withdrawal symptoms with opioids as well as with a combination of non-opioid medications such as alpha 2 agonists, benzodiazepines, and/or antiemetics as needed. Besides simply managing withdrawal symptoms, clinicians can further improve the care of patients with OUD through initiating maintenance treatment with MOUD, ideally with opioids used in the initial management of withdrawal. Opioid detoxification is an inferior method of primary treatment and is associated with relapse and poor outcomes. In contrast, treatment with MOUD using methadone or buprenorphine is associated with superior treatment outcomes and reduced relapse compared to detoxification alone. Treatment with MOUD using methadone or buprenorphine can be successfully used in the hospital setting. A novel low dose approach to buprenorphine induction may be useful in minimizing precipitated withdrawals in patients who have recently used or received opioids, which makes this an attractive option in the hospital where patients are frequently on opioids for acutely painful conditions. The hospital setting also provides a valuable opportunity for clinicians to address harm reduction in patients with OUD. Finally, clinicians can improve the long-term outcomes of patients with OUD by ensuring a smooth discharge with adequate and timely follow-up.</p><p><strong>Conclusion: </strong>Proper management of opioid withdrawal and initiation of MOUD in the hospital can improve outcomes in patients with OUD.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":" ","pages":"251-258"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40507791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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