Hans Journal of Ophthalmology最新文献_第2页

Evaluation of Stereo Visual Function in Patients with Age-Related Cataract Using Cerebral Visual Inspection Techniques 应用脑视觉检查技术评价老年性白内障患者的立体视觉功能

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2022.113032

思琪罗

引用次数: 0

Non-Open Sky Penetrating Keratoplasty Combined with Phacoemulsification and Intraocular Lens Implantation 非开放性穿透性角膜移植术联合超声乳化人工晶状体植入术

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2019.84022

勇姚

引用次数: 0

Advances of Cornea Transplantation 角膜移植研究进展

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2021.102009

芊黎

引用次数: 0

Preparation and Formulation Optimization of Loaded Celastrol Nanostructure Lipid Carriers for Topical Ocular Application 眼用负载雷公酚纳米结构脂质载体的制备及配方优化

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2019.84025

Yingzhi Guo, Zhen Liang, Zhen Zhang, Jing-bo Wang, Junjie Zhang

{"title":"Preparation and Formulation Optimization of Loaded Celastrol Nanostructure Lipid Carriers for Topical Ocular Application","authors":"Yingzhi Guo, Zhen Liang, Zhen Zhang, Jing-bo Wang, Junjie Zhang","doi":"10.12677/hjo.2019.84025","DOIUrl":"https://doi.org/10.12677/hjo.2019.84025","url":null,"abstract":"Objective: The central composite design-response surface methodology (CCD-RSM) was used to optimize the application of tricorne nanostructured lipid carrier (CEL-NLC) in the local application of eyes. Methods: The lipid with the best solubility was screened out by determining the solubility of celastrol in different lipids. CEL-NLC was prepared by microemulsion technique. Quality of solid lipid (X1), quality of liquid lipid (X2), surfactant/cosurfactant (X3) as objects of investigation, while particle size (Y1), encapsulation efficiency (Y2) and drug loadings rate (Y3) as dependent variables, the optimal prescription was obtained by CCD-RSM and verified subsequently. Results: The best prescription of CEL-NLC was Celastrol 0.04 g, palmitic acid 0.09 g, oleic acid 0.18g, tween-80 4.34 g and Glycerine 2.16 g. The encapsulation efficiency was (75.28 ± 3.44)%; the drug loading rate was (0.45 ± 0.02)%; the particle size was (18.66 ± 2.63) nm. The PDI was 0.39 ± 0.03. The deviation between the measured and predicted values was less than 5%. Conclusion: The optimized CEL-NLC obtained by CCD-RSM has high encapsulation efficiency, small particle size and good stability, which can be further used in the follow-up study of local application of Celastrol in eyes.","PeriodicalId":349897,"journal":{"name":"Hans Journal of Ophthalmology","volume":"62 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132286883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Long-Term Clinic Efficacy of Laser Subepithelial Keratomileusis for Ultra-High Myopia 激光上皮下角膜磨镶术治疗超高近视的长期临床疗效观察

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2022.111014

宁高

引用次数: 0

Clinical Observation of Tear Film Oriented Therapy 泪膜导向疗法的临床观察

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2022.111016

翠薇张

引用次数: 0

Residual Anterior Chamber Nuclear Mass after Phacoemulsification: A Case Report 超声乳化术后前房残余核团1例

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2021.102010

丽莲谢

{"title":"Residual Anterior Chamber Nuclear Mass after Phacoemulsification: A Case Report","authors":"丽莲谢","doi":"10.12677/hjo.2021.102010","DOIUrl":"https://doi.org/10.12677/hjo.2021.102010","url":null,"abstract":"晶状体核块或晶状体碎片残留常发生于白内障超声乳化术中出现后囊破裂的患者中；手术中顺利，无后囊破裂的患者中，术后晶状体核块残留发生很少。术后残留晶状体核块可以继发眼压升高、角膜水肿、葡萄膜炎和其它并发症，这种并发症可能导致视功能障碍。本文报道一例Ⅳ级硬核年龄相关性白内障患者，白内障超声乳化及人工晶状体植入手术过程顺利，术中没有发生后囊破裂等并发症的患者，术后1周发现前房晶状体核块残留，导致角膜水肿，经二次手术行前房冲洗术取出残留晶状体核块，术后恢复良好。 Residual lens nucleus or lens fragments often occur in patients with posterior capsule rupture during phacoemulsification, but rarely in patients without posterior capsule rupture. Intraocular pressure, corneal edema, uveitis and other complications can be secondary to residual lens nucleus after surgery, which may lead to visual dysfunction. This paper reported a case of age-related cataract with grade IV hard nucleus. Phacoemulsification and intraocular lens implantation was successfully performed. Posterior capsule rupture didn’t occur during the operation. One week after the operation, a residual lens nucleus was found in the anterior chamber, which led to corneal edema. The residual lens nucleus was removed by anterior chamber irrigation and recovered well.","PeriodicalId":349897,"journal":{"name":"Hans Journal of Ophthalmology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125725967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect and Safety Analysis of Levofloxacin Eye Drops in the Treatment of Severe Bacterial Keratitis and Conjunctivitis 左氧氟沙星滴眼液治疗重度细菌性角膜炎和结膜炎的疗效及安全性分析

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2023.122010

冬严

引用次数: 0

Research Progress of OCT and OCTA Imaging Features in Retinal Vein Occlusion 视网膜静脉闭塞的OCT和OCTA影像特征研究进展

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2023.123016

都吉雅李

{"title":"Research Progress of OCT and OCTA Imaging Features in Retinal Vein Occlusion","authors":"都吉雅李","doi":"10.12677/hjo.2023.123016","DOIUrl":"https://doi.org/10.12677/hjo.2023.123016","url":null,"abstract":"Retinal vein occlusion (RVO) is the occlusion of the retinal venous system by thrombosis. It is the second most common retinal vascular disease and an important cause of visual loss and impairment. Optical coherence tomography (OCT) is a reliable imaging examination for the diagnosis of macular edema caused by RVO, which can qualitatively and quantitatively evaluate the structure of each layer of the retina. Optical coherence tomography angiography (OCTA) enables noninvasive, depth selective visualization of retinal and choroidal vascular networks by detecting intra-vinal blood flow, resulting in three-dimensional high-resolution images that cannot be achieved with conventional fluorescein angiography (FFA). Therefore, OCTA can be used to observe micro-perfusion of retinal and choroidal vessels, as well as changes in retinal and choroidal vessels during different pathological types and treatments. This article reviews the application of OCT and OCTA imaging features in the development of RVO and its anti-vascular endothelial growth factor (VEGF) therapy, in order to provide reference for assessing the severity of RVO, adjusting the treatment plan and judging the prognosis of the disease.","PeriodicalId":349897,"journal":{"name":"Hans Journal of Ophthalmology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129166922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

After Implantation of False Diopter Intraocular Lens: A Case of IOL Implantation without Viscoelastic Agent 人工晶状体植入术后无粘弹性剂人工晶状体植入术1例

Hans Journal of Ophthalmology Pub Date : 1900-01-01 DOI: 10.12677/hjo.2020.93030

惠春杨

引用次数: 0