P. Machado, J. G. Camponogara, C. S. Rodrigues, L. B. Jacques, L. Valandro, M. Rippe
{"title":"Influence of number and position of porcelain specimens in the furnace on flexural strength and translucency","authors":"P. Machado, J. G. Camponogara, C. S. Rodrigues, L. B. Jacques, L. Valandro, M. Rippe","doi":"10.20396/bjos.v22i00.8671377","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8671377","url":null,"abstract":"The aim of this study was to investigate the influence of the quantity and positioning of feldspathic ceramic specimens inside the furnace on their flexural strength and translucency. The tested hypotheses were that the arrangement of specimens in the furnance would not influence 1) the translucency or 2) the biaxial strength of the porcelain. Methods: Ninety porcelain specimens were made (1.2 mm thickness and 13.5 mm diameter) and assigned into two main groups (n=15): G1 group - 15 firing cycles containing only one specimen each, always at the center of the refractory; and G5 group - 15 firing cycles containing five specimen each, where one specimen was at the center of the refractory and four specimens positioned equidistantly on the periphery. The translucency test was performed using a spectrophotometer, followed by the flexural strength test, according to ISO 6872:2015. T-student test was performed for both the mechanical and optical obtained data. Results: The flexural strength of the porcelain was not affected by the positioning (center x periphery) of the specimens inside the furnace (p =0.08), but the translucency was affected (periphery > center; p =0.009). Regarding to the number of feldspathic ceramic specimens, the biaxial flexural strength was affected (p =0.025), as well as the translucency (p <0.05). Conclusion: A higher quantity of feldspathic ceramic specimens for each firing cycle decreased its biaxial flexural strength and translucency. Also, specimens positioned at the center of the refractory became less translucent than those positioned at the periphery.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"113 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138599577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isadora Augusta da Silveira, Tomaz Alves da Silva Neto, L. D. Conceição, Gustavo G. Nascimento, Marina Sousa Avezedo, R. Lund
{"title":"Physical violence in children and adolescents","authors":"Isadora Augusta da Silveira, Tomaz Alves da Silva Neto, L. D. Conceição, Gustavo G. Nascimento, Marina Sousa Avezedo, R. Lund","doi":"10.20396/bjos.v22i00.8671486","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8671486","url":null,"abstract":"Aim: This study aimed to investigate the prevalence of physical violence and head and neck injuries among children and adolescents who suffered physical aggression, firearm aggression, and white gun aggression referred to the Legal Medical Department in a southern city in Brazil. Methods: This study was performed at Legal Medical Department in the city of Pelotas, RS, Brazil, from January 2011 to December of 2015. Data were collected from medical reports of children and adolescents (0-19 years old). Demographic information such as sex, age, and skin color was collected. Data were submitted to Chi-square test and multivariate Poisson regression analysis. Results: In this study, 2,716 physical examination reports were analyzed, with a total of 2,171 exams resulting from violence; lesions that had physical aggression as their etiology (1,951) had a higher prevalence. The analysis of the exams revealed that the majority were adolescents (90,05%), white (84.09%), and female (50.21%). The head and neck regions were affected in most cases of violence (57.90%). In the adjusted model, the occurrence of injuries in the head and neck region was higher in males (PR 1.16, CI 95% 1.08 - 1.25), among adolescents (PR 1.28, CI 95% 1.10 - 1.48) and in victims of physical aggression compared to victims of the firearm (2.81, CI 95% 1.79 - 4.40). Conclusion: The results revealed a high prevalence of head and face injuries in victims of violence and that there was a greater prevalence of physical violence among adolescents compared to children and males.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":" 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139197267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of honey-lemon spray on recurrent aphthous stomatitis comparing to Triamcinolone ointment","authors":"M. Shirzaiy, G. Heydarirad, Samaneh Bakhshipour","doi":"10.20396/bjos.v22i00.8667560","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8667560","url":null,"abstract":"Recurrent aphthous stomatitis (RAS) is recurrent and painful diseases of the oral mucosa that can be very painful and annoying despite their small size. There is no definitive cure for this disease and the usual treatments are mainly based on pain control. The aim of this study was to investigate the effect of honey-lemon spray (mucotin) in the treatment of recurrent aphthous stomatitis. Methods: This study is a randomized controlled clinical trial conducted in 2020 at Zahedan University of Medical Sciences on 46 RAS patients. The participants were randomly assigned to the intervention (mucotin) or control groups (Triamcinolone ointment) equally (23 patients in each group). Patients were evaluated for the severity of pain and ulcer size. Evaluations were performed on days 0, 2, 7 of the treatment using VAS. Data were analyzed using ANOVA statistical test. Results: The inner aspect of the lower lip was the most common site of RAS in the participants (48.8%) and the lowest site went for hard palate (2.4%). Four items including pain, burning sensation, necrosis area, and erythematous area were evaluated in both groups. There was no significant difference in all parameters before the treatment period (day 0). The mean pain score, burning sensation, necrosis, erythematous areas were not different in days 0, 2 and 7 between groups respectively (p=0.849, p=0.105, p=0.917, p=0.442). Conclusion: Honey-lemon spray (Mucotin) and topical corticosteroid have similar effects in RAS treating, So Mucotin can be used as the first line of treatment for RAS lesions. This herbal medicine has no side effects.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"176 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139230906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adeola T. Williams, O. Denloye, Bamidele O. Popoola, Johnson A. Adeniji, O. M. Adewumi, Toluwanimi E. Akinleye, Clara A. Akinyamoju
{"title":"Viability of periodontal ligament cells in selected transport media for avulsed teeth","authors":"Adeola T. Williams, O. Denloye, Bamidele O. Popoola, Johnson A. Adeniji, O. M. Adewumi, Toluwanimi E. Akinleye, Clara A. Akinyamoju","doi":"10.20396/bjos.v22i00.8671499","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8671499","url":null,"abstract":"To compare the viability of periodontal ligament (PDL) cells stored in Hanks Balanced Salt Solution (HBSS) with those in readily available transport media over a variable period of time. Methods: Periodontal ligament cells harvested from premolars freshly extracted for orthodontic reasons were cultured for exponential growth. The cells were exposed to egg white, evaporated milk, water and Hanks Balanced Salt Solution (HBSS) at room temperature. Their viability was evaluated after 30 minutes, 1 hour and 3 hours with the tetrazolium salt-based colorimetric assay (MTT assay). Statistical analysis was done using the IBM® SPSS version 23.0 software. Comparison between the Mean Optical Densities (MODs) of the cells stored in HBSS and other media at each time interval was done using the independent t test. Repeated measure ANOVA and Tukey post-hoc test were also carried out to compare the MOD of cells within each medium over time. The level of significance was set at p <0.05. Result: The PDL cells stored in egg white had higher MODs than those in HBSS at 30 minutes and 1 hour. Conversely, the MODs of the cells stored in milk and water were lower than those in HBSS at all the studied points. There was a significant difference in the viability of the cells stored in HBSS and water at all the time points (p<0.05). Conclusion: For up to an hour, egg white was found to perform better than HBSS in supporting the viability of PDL cells.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139228671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Bem, A. Polizello, H. Cabral, N. G. Rosa-Garzon, Carem Gledes Vargas Rechia, C. P. Aires
{"title":"Mango peel as a potential enzyme inducer in Trichoderma harzianum","authors":"J. Bem, A. Polizello, H. Cabral, N. G. Rosa-Garzon, Carem Gledes Vargas Rechia, C. P. Aires","doi":"10.20396/bjos.v22i00.8672955","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8672955","url":null,"abstract":"Water-insoluble exopolysaccharides (I-EPS) are a virulence factor for dental biofilms. It has already been demonstrated that mango pulp induces the secretion of glucan-hydrolytic enzymes in the fungus Trichoderma harzianum, and that they have an effect on I-EPS from young biofilms. Aim: Evaluate the effect of mango peel as an enzyme inducer in T. harzianum, and the effect of enzymes secreted on mature biofilms. Methods: Fractions of the peel (PL) and ethanol-precipitated pulp (PP) of Tommy Atkins mangoes were sterilized and added to a culture medium containing T. harzianum for induction of hydrolytic enzymes. After 192 h, the culture medium was centrifuged and the supernatant (enzyme extract) was used as treatment on S. mutans biofilms (n=9): a) NaCl 0.9 %; b) 0.12 % chlorhexidine digluconate; and c) extract of enzymes induced by PL or PP. Acidogenicity, bacterial viability, quantification of insoluble polysaccharides, and three-dimensional analysis of the biofilm by scanning electron microscopy (SEM) was performed. Data were analyzed by ANOVA followed by the Tukey test (α=5 %). Results: The hydrolytic enzymes did not alter the metabolism or bacterial viability of the biofilm (p<0.05). Although the images obtained by SEM suggest some degree of matrix degradation, the quantification of I-EPS for the PL and PP groups did not differ from the control group (p>0.05), suggesting a slight effect on the disorganization of the mature S. mutans biofilm. Conclusion: The results suggest that mango peel fraction can induce secretion of mutanase by T. harzianum, however in an insufficient amount to generate significant degradation on cariogenic biofilm.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"56 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139252603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolas Nicchio, Fausto Frizzera, Sergio Lins de Azevedo Vaz, Fernanda Coelho Silva, Elcio Marcantonio Junior
{"title":"Socket regeneration after immediate loading implants with tissue and bone graft","authors":"Nicolas Nicchio, Fausto Frizzera, Sergio Lins de Azevedo Vaz, Fernanda Coelho Silva, Elcio Marcantonio Junior","doi":"10.20396/bjos.v22i00.8672780","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8672780","url":null,"abstract":"Evaluation of ridge alteration after 1 year follow up after immediate loading implant placement. Methods: Ten patients were included in the study, in whom the ridge volume, height, and thickness were evaluated from region of interest (ROI) of tomographic images of the operated areas (test group) and compared to the opposite tooth (control group). Results: After one year, there was no implant loss and all patients were satisfied with the treatment. In the test group there was a statistically significant increase in ridge height (2.89±1.05 mm) when compared to the control group. No significant difference in relation to ridge volume and thickness was observed. In the intragroup evaluation, a significant gain in ridge height (2.65±3.08 mm) was observed when compared to baseline. Conclusion: The placement of an immediate implant, temporary crown, and tissue regeneration in sockets with buccal defects promotes the regeneration of the buccal wall while preventing the reduction of bone volume and thickness.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134907490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Layla Beatriz Barroso de Alencar, Ismael Lima Silva, Samara Crislâny Araújo de Sousa, Vitória Freitas de Araújo, William Harvey Machado de Sousa Lacerda Oliveira, Cristiano Moura
{"title":"Prevalence of bruxism among college students","authors":"Layla Beatriz Barroso de Alencar, Ismael Lima Silva, Samara Crislâny Araújo de Sousa, Vitória Freitas de Araújo, William Harvey Machado de Sousa Lacerda Oliveira, Cristiano Moura","doi":"10.20396/bjos.v22i00.8668151","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8668151","url":null,"abstract":"Evaluate the prevalence of bruxism and to analyze what are the possible associated factors with this condition in students of a Brazilian university. Methods: This was a cross-sectional study, with a sample of 230 students randomly selected among undergraduate courses at a university center. The dependent variable was the presence of awake bruxism and sleep bruxism. The independent variables were sociodemographic factors, smoking, alcohol consumption, oral habits and stress perception (Perceived Stress Scale- PSS 14). Descriptive statistics and bivariate analysis were used. Results: The prevalence of awake bruxism was 28.7% and was associated with the independent variables: course (degree program), gum chewing habits, chin hand placing, facedown sleeping and one-side biting. Sleep bruxism had a 7.0% prevalence and displayed association with gum chewing, pens/pencils/objects biting, tongue/lips/cheeks biting, nails biting and one-side biting. Perceived stress was not associated with either type of bruxism. Conclusion: Bruxism has an important prevalence among university students, especially when distinguishing between awake bruxism and sleep bruxism.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135111478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A multilevel analysis model for dental caries determinants in independently-living elderly","authors":"Natália Teixeira Tavares Branco, Raquel Conceição Ferreira, Jéssica Vancarla Rodrigues de Souza, Allyson Nogueira Moreira, Ivana Márcia Alves Diniz, Cláudia Silami Magalhães","doi":"10.20396/bjos.v22i00.8670692","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8670692","url":null,"abstract":"To evaluate the prevalence of untreated caries and its association with biological, individual, and environmental variables in independently-living elderly people. Methods: This cross-sectional study included 72 elderly (≥60 years) patients of a university dental clinic in Belo Horizonte, Brazil. Sociodemographic data, systemic diseases, medications, and free sugar intake were collected. Visible plaque, Decayed, Missing, and Filled Teeth (DMFT), and Decayed and Filled Root (DFR) indexes were assessed through clinical examination. Unstimulated saliva was collected to determine salivary flow, pH, and buffering capacity. Descriptive analysis and multilevel logistic regression analysis were performed following a dental caries theoretical model (p <0.05, 95% CI). Results: The mean DMFT and DFR were 24.44 (SD=4.59) and 3.21 (SD=2.93), respectively. The prevalence of untreated caries was 61.11%. In the adjusted multilevel regression model involving 1639 teeth, untreated dental caries was significantly associated with the presence of biofilm (OR = 1.84; 95% CI: 1.24–2.74), salivary buffering capacity (OR = 0.87; 95% CI: 0.77–0.99) and per capita income (OR = 0.06; 95% CI: 0.004–0.74). Conclusion: The experience of dental caries was widespread among independently-living elderly patients, and its variability was best explained by the presence of biofilm, reduced salivary buffering capacity, and low per capita income. A comprehensive assessment is needed of the biological, individual, and environmental factors related to the presence of dental caries in independently-living elderly people.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135780567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of pH-cycling and abrasion wear on the mechanical properties of conventional and bulk fill resin composites","authors":"Larissa Daniela Orlando, Rodrigo Barros Esteves Lins, Marina Rodrigues Santi, Luís Roberto Marcondes Martins","doi":"10.20396/bjos.v22i00.8668637","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8668637","url":null,"abstract":"The objective of this study was to evaluate the effect of abrasion wear on surface roughness and microhardness of different commercially available resin composites simulating pH-challenges of the oral cavity. Methods: Three resin composites (RC) were used in this study: one conventional: Z250; and two bulk fill resin composites (BRC): Tetric N-Ceram (TNC) and Sonic Fill (SF). The RC was inserted in a prefabricated mold (15mm wide x 4mm thickness) in two layers, or in a single layer for BRC. Thirty samples were prepared and surface roughness (Ra) and Knoop microhardness (KHN) test were performed at three different time-points of evaluation: baseline (24h after sample preparation); partial (after pH cycling); and final (after simulated toothbrushing procedure). Two samples of each group were selected after different treatments and analyzed descriptively on a scanning electron microscopy (SEM). Data from Ra and KHN were analyzed by two-way repeated-measures ANOVA and Bonferroni’s post-hoc test with a significance level set at 5%. Results: Ra increased for all groups (p<0.001), at the final time-point, Z250 and TNC groups present the highest values. Oppositely, KHN decreased for all groups (p<0.001), Z250 group showed the highest KHN values for all time-points (p<0.001). The SEM imagens showed a regular surface for samples cycled and irregular with inorganic particles exposed for samples toothbrushed. Conclusion: pH-cycling and simulated toothbrushing affected the superficial properties (roughness and Knoop microhardness), as observed at SEM imagens, with irregular surface with inorganic particles exposure.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136142211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of lingual frenotomy on the breastfeeding improvement","authors":"Camila Fontanella Possamai, Antônio Augusto Schäfer, Micaela Rabelo Quadra, Carla Damasio Martins, Fernanda Oliveira Meller","doi":"10.20396/bjos.v22i00.8668415","DOIUrl":"https://doi.org/10.20396/bjos.v22i00.8668415","url":null,"abstract":"To evaluate breastfeeding in babies up to six months of age before and after frenotomy surgery in a reference hospital in a city from Santa Catarina state. Methods: An observational quality improvement study, carried out with babies up to six months of age undergoing frenotomy and their mothers in a reference hospital in southern Santa Catarina state. A questionnaire was applied to the mothers in two moments (before and after the surgery), with information regarding breastfeeding, sociodemographic, anthropometric and behavioral characteristics of them and of the babies. Descriptive analyzes were performed and the association between breastfeeding and the independent variables was assessed through Pearson’s chi-square and Fisher’s exact tests, using a 5% significance level. Results: A total of 74 children were studied, with 48 of them returning after surgery. 83.8% were breastfed before surgery and 64.9% after surgery. Before surgery, 58.1% of children effectively took the breast at once. After surgery, this prevalence was 83.3% (p=0.015). Before surgery, 75.9% of the mothers reported not feeling pain, while, after surgery, almost all of them (95.8%) reported this (p=0.004). Most mothers reported improvement in grip (83.3%), increase in the duration of breastfeeding (69.0%), improvement of baby’s breathing (75.0%), and an increase in the frequency of breastfeeding (51.7%). Conclusions: There was a decrease in the prevalence of breastfeeding after frenotomy. However, there was an improvement in the babies ‘grip and breathing and a reduction in the mothers’ pain when breastfeeding. It is emphasized the need to implement multidisciplinary actions in both primary and hospital care to assist mothers in order to prolong the duration of exclusive breastfeeding.","PeriodicalId":34984,"journal":{"name":"Brazilian Journal of Oral Sciences","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136142866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}