Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa3540

Ignacio Fernández Ceballos, Julieta Gonzalez Anaya, Juan Martín Nuñez Silveira, Emilio Steinberg, Leiniker Navarro Rey, Gabriel Elias Vega, Ivan Huespe, Indalecio Carboni Bisso, Marcos Las Heras, Rodriogo Cornejo

{"title":"Changes in lung volumes during bronchoalveolar lavage according to bedside position. Case Series","authors":"Ignacio Fernández Ceballos, Julieta Gonzalez Anaya, Juan Martín Nuñez Silveira, Emilio Steinberg, Leiniker Navarro Rey, Gabriel Elias Vega, Ivan Huespe, Indalecio Carboni Bisso, Marcos Las Heras, Rodriogo Cornejo","doi":"10.1183/13993003.congress-2023.pa3540","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa3540","url":null,"abstract":"Introduction: Bronchoalveolar lavage (BAL) is used in the diagnosis of pneumonia in patients with Mechanical Ventilation. Its performance involves the instillation of saline solution, which is associated with lung collapse and worsening hypoxemia. Positioning the patient9s head at 0° could increase the loss of lung volume and oxygenation. A therapeutic option to mitigate this effect could be to perform this procedure with head elevation at 30°. Aims and Objectives: The study aimed to assess changes in lung volumes in relation to the position of the patient9s head. Methods: Case series of 3 patients. End-expiratory Lung Impedance (EELI) measurements were performed (Pulmovista V500) in the following situations: Head at 30° before BAL, 0° before BAL, 0° post-BAL and 30° post-BAL. Results: In patients 1 and 2, the change of headrest from 30° to 0° before BAL resulted in an overall decrease in EELI (83.1% - 20.2%). Performing BAL increased the drop in EELI, with greater expression in the regions where BAL was performed. After BAL was completed, in both patients, the repositioning of the headrest to 30° produced an increase in global EELI without reaching the values obtained with the headrest at 30° before BAL (Patient 1 80.5% - Patiente 2 52.9%). In patient 3, the change of head position from 30° to 0° after BAL showed a 12.5% decrease in EELI. Performing BAL deepened the drop in overall EELI (-44.4%), as did repositioning the headrest to 30° (-70%) post-BAL. Conclusion: Changes in bedside positioning before BAL resulted in a reduction in EELI in all 3 patients. The repositioning of the head after BAL had a heterogeneous behavior increasing the EELI in patients 1 and 2, and decreasing it in patient 3","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136259130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumonectomy in the surgery of pulmonary Hydatid cysts: A therapeutic option that is sometimes unavoidable 肺包虫囊肿手术中的全肺切除术:有时是不可避免的治疗选择

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa3538

Kaouther Ben Amara, Imen Bouassida, wifek SAIDANI, Sarra Zairi, Hazem Zribi, Mehdi Abdennadher, Imen Sahnoun, Adel Marghli, Sarra Zairi

{"title":"Pneumonectomy in the surgery of pulmonary Hydatid cysts: A therapeutic option that is sometimes unavoidable","authors":"Kaouther Ben Amara, Imen Bouassida, wifek SAIDANI, Sarra Zairi, Hazem Zribi, Mehdi Abdennadher, Imen Sahnoun, Adel Marghli, Sarra Zairi","doi":"10.1183/13993003.congress-2023.pa3538","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa3538","url":null,"abstract":"Introduction: A parenchyma-saving operation is the rule in the treatment of pulmonary hidatid cyst (PHC). However, pneumonectomy can be necessary in some situations. Material : Retrospective study over a period of 20 years including 5 patients who underwent pneumonectomy for pulmonary hydatidosis. Results: The average age was 45 years old with a female predominance of 80%. Three patients had a history of complicated PHC treated by cystectomy (1 case) and liver hydatid cyst operated on (2 cases). Two patients presented a pulmonary hydatid embolism treated medically (1 case) and surgically (1 case). The main symptoms were chest pain (5 cases), dry cough (5 cases). Chest computed tomography, performed in all patients, revealed voluminous fluid tone masses, homogeneous well limited, occupying one lobe (1 cases), two lobes (2 cases) and three lobes (2 cases) with pulmonary hydatid embolism in two cases. Four patients had pneumonectomy for a destroyed hepatized lung and one patient a totalisation pneumonectomy, through a posterolateral thoracotomy in all cases. The mean duration of postoperative drainage was 3 days. The histological study confirmed the diagnosis. The postoperative course was simple for 3 patients. Two postoperative complications were reported: Cardiac arrythmia and postoperative pneumonia. Conclusion : In pulmonary hydatidosis surgery, lung tissue should be preserved and resection should be avoided whenever it is possible. However, Pulmonary resection becomes unavoidable if irreversible changes have occurred throughout the lung and a large amount of parenchyma is attached to the cyst. This highlights the importance of rigourous prophylaxis and early diagnosis.","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"368 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136259437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Observer agreement in the diagnosis of interstitial lung diseases 间质性肺疾病诊断的观察者一致

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa4012

Rebecca Saray Marchesini Stival, Bruno Pedrazzani, Ariele Haagsma, Cristina Pellegrino Baena

{"title":"Observer agreement in the diagnosis of interstitial lung diseases","authors":"Rebecca Saray Marchesini Stival, Bruno Pedrazzani, Ariele Haagsma, Cristina Pellegrino Baena","doi":"10.1183/13993003.congress-2023.pa4012","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa4012","url":null,"abstract":"Introduction: The density of radiologists per inhabitant is 7.5/100 thousand in the United Kingdom; in Brazil, it is 6.2, and in some areas, 1.5. Thoracic Radiologists are even scarcer. Pulmonologists frequently diagnose features associated with pulmonary fibrosis. Objective: To determine the interobserver agreement in diagnosing features associated with interstitial lung diseases. Methods: 63 chest CTs of covid-19 outpatients discharged from public hospitals of Curitiba/PR/Brazil from June 2020 to December 2021 were evaluated by an experienced pulmonologist and a thoracic radiologist. Each chest CT was assessed for the following characteristics: presence or absence of traction bronchiectasis and parenchymal bands in any lung lobe, independent of the severity, and qualitative visual evaluation was used to determine the extension of GGO, characterized: mild (1%–24%), moderate (25%–49%), severe (50–74%); very severe (≥ 75%). In addition, interobserver agreement for two observers in overall image quality or CT features was determined for a nonparametric Cohen´s Kappa test. Results: Traction bronchiectasis was identified for the thoracic radiologist in 14 (22.2%) and parenchymal bands in 38 (60.3%) CT, for the pulmonologist in 9 (14.3%), 32 (50.8%), respectively. The kappa agreement of traction bronchiectasis between professionals was 0,632 (p=<0.001), interpreted as substantial, for parenchymal bands was k=0.49 (p<0.001), with a moderate agreement. On the Other hand, extension GGO had no agreement (k=0.221; p= 0.001). Conclusions: Interobserver agreement in the diagnosis of traction bronchiectasis, the main feature associated with pulmonary fibrosis, was substantial.","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136259572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilising computer vision artificial intelligence to identify defects in airway ciliary motility and mucociliary clearance 利用计算机视觉人工智能识别气道纤毛运动和纤毛粘液清除缺陷

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa2293

Mathieu Bottier, Andreia Lucia Do Nascimento Pinto, Emily Howieson, Britt J Van Akker, Oliver Hamilton, Ioannis Katramados, Jane Davies, Amelia Shoemark, Claire Hogg, Thomas Burgoyne

{"title":"Utilising computer vision artificial intelligence to identify defects in airway ciliary motility and mucociliary clearance","authors":"Mathieu Bottier, Andreia Lucia Do Nascimento Pinto, Emily Howieson, Britt J Van Akker, Oliver Hamilton, Ioannis Katramados, Jane Davies, Amelia Shoemark, Claire Hogg, Thomas Burgoyne","doi":"10.1183/13993003.congress-2023.pa2293","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa2293","url":null,"abstract":"Mucociliary clearance is an essential defence mechanism against chronic airway infection and inflammation. Defects in ciliary motility are either primary, as in primary ciliary dyskinesia (PCD), or secondary. Identification of mucociliary clearance defects allows the implementation of appropriate management. High-speed video-microscopy (HSVM) is used to assess cilia motility from nasal biopsy samples. It is a time consuming and subjective requiring significant expertise. Computer vision can improve the identification of cilia motility defects by minimising subjectivity and reducing the cost and time to analyse samples. Using an artificial intelligence platform (Intel® Geti™), we have trained several models using archived HSVM videos from patients referred to the Royal Brompton Hospital who were diagnosed with PCD and display a range of ciliary motility phenotypes and non-PCD controls. The videos used are converted to optical flow to provide temporal information to the machine learning algorithm. We are training the platform to classify different categories of beat pattern: Immotile, Normal, Reduced Amplitude and Rotation. Models also include assessing sample quality and cilia beating orientation. The preliminary data based on projects currently in development are promising: the model classifying normal beating vs immotile cilia (around 30,000 frames) has a predictive accuracy of 100% and the beat pattern recognition model (around 25,000 frames) has a predictive accuracy of 97%. Further training and testing are ongoing, and more models are being developed to include a greater range of motility phenotypes and to encompass chronic inflammatory lung diseases.","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136201067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative CT lung alterations and lung function in COVID-19 associated ARDS: 1-year follow-up COVID-19相关ARDS的定量CT肺部改变和肺功能:1年随访

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa3528

Riccardo Ripamonti, Bianca Corrò, Silvia Pagani, Stefania Raschi, Pierfranco Usai, Cristiano Bonacina, Roberta Cattaneo, Monica Bernareggi, Chiara Melacini, Serena Bencini, Martina Piluso, Francesca D'Arcangelo, Luca Parachini, Chiara Milano, Roberta Ciceri, Angela Brancaforte, Marcello Intotero, Paolo Scarpazza

{"title":"Quantitative CT lung alterations and lung function in COVID-19 associated ARDS: 1-year follow-up","authors":"Riccardo Ripamonti, Bianca Corrò, Silvia Pagani, Stefania Raschi, Pierfranco Usai, Cristiano Bonacina, Roberta Cattaneo, Monica Bernareggi, Chiara Melacini, Serena Bencini, Martina Piluso, Francesca D'Arcangelo, Luca Parachini, Chiara Milano, Roberta Ciceri, Angela Brancaforte, Marcello Intotero, Paolo Scarpazza","doi":"10.1183/13993003.congress-2023.pa3528","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa3528","url":null,"abstract":"Introduction: COVID-19 pneumonia often causes long term radiological and functional lung alterations. Aims and objectives: Primary endpoint of our retrospective study was to evaluate the frequency and the extension after 1 year from the discharge of CT alterations (conventional and quantitative study) in the lungs of patients (pts) admitted to Vimercate Hospital for COVID-19 associated ARDS (CARDS). Secondarily, alterations in pulmonary function tests (PFTs) and 6 minute walking distance (6MWD) were investigated. Methods: 66 pts with CARDS entered the study and no one had previous chronic lung disease. Volumetric data were measured with Synapse 3D software and were compared with 20 healthy subjects of the same age. Categorical data were expressed as frequencies and percentages. Continuous variables were represented using median values. Multivariate logistic regression was performed for every category of data. Statistical significance was considered for p-value <0.05. Results: At 1-year follow-up only 5/66 pts (7.6%) showed a normal CT pattern. Conventional CT patterns were mostly ground-glass opacities, reticulations, subpleurical curves, traction bronchiectasis and fibrotic-like alterations. Quantitative analysis pointed out that the median lung volume of pts was significantly lower than that of the control group (p=0.011). The median compromised lung volume (VCo), including emphysema, interstitial impairment and consolidation was significantly higher in CARDS than in the control group (p≤0.001). DLCO, TLC and 6MWD were found to be negatively correlated with VCo. Conclusions: Our study highlights the need of a longer radiological and functional follow-up post-CARDS.","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"231 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136259453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiation exposure in primary spontaneous pneumothorax patients. 原发性自发性气胸患者的辐射暴露。

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa3539

Bart P.C. Hoppe, Gijs C.M. Ven, Tijmen, J.W.T. Van De Wel, Rajen, S.R.S. Ramai, Pieter E. Postmus

{"title":"Radiation exposure in primary spontaneous pneumothorax patients.","authors":"Bart P.C. Hoppe, Gijs C.M. Ven, Tijmen, J.W.T. Van De Wel, Rajen, S.R.S. Ramai, Pieter E. Postmus","doi":"10.1183/13993003.congress-2023.pa3539","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa3539","url":null,"abstract":"Introduction: Primary spontaneous pneumothorax (PSP) patients are probably exposed to a high burden of radiation. These patients are usually young and radiation exposure can be harmful. Aim and objectives The aim of this study is to analyse the amount of radiation exposure in primary spontaneous pneumothorax patients during the first event and subsequent episodes. Methods: Patients with primary spontaneous pneumothorax were retrospectively analyzed for the number of chest x rays and chest CT scans related to the diagnosis/treatment of the pneumothorax in an academic (Leiden University Medical Center) and a teaching hospital (Alrijne) in the Netherlands. The number of imaging studies was counted for the first episode and all subsequent episodes of ipsilateral and contralateral recurrence. Results: From January 2015 till December 2022 the medical files of 180 primary spontaneous pneumothorax patients were analyzed. An average number of 20 chest x rays were performed per patient. In the academic center half of these patients received one or more chest CT scans. In the teaching hospital a chest CT was performed in one third of all pneumothorax patients. Conclusions: These findings suggest that the radiation exposure is high in spontaneous pneumothorax patients. Aims to reduce recurrence (smoking cessation and detecting and treating high risk cases with thoracic surgery for the first episode such as Birt-Hogg-Dubé patients), as well as other techniques to confirm a diagnosis of pneumothorax or evaluate the efficacy of chest tube drainage (ultrasound) are needed 1,2. References 1. Critical Care 2013; 17(5): R208 2. Chest 2011; 140: 859-66","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136259538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seven years of functional lung MRI in children: experiences of more than 900 matrix-pencil decomposition (MP-)MRI measurements in clinics and research 7年儿童肺功能MRI:临床和研究中900多例基质铅笔分解(MP-)MRI测量的经验

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa3996

Carmen Streibel, C. Corin Willers, Grzegorz Bauman, Orso Pusterla, Oliver Bieri, Enno Stranzinger, Ben Brabandt, Marion Curdy, Yasmin Salem, Carmen Casaulta, Insa Korten, Sophie Yammine, Philipp Latzin, Elisabeth Kieninger

{"title":"Seven years of functional lung MRI in children: experiences of more than 900 matrix-pencil decomposition (MP-)MRI measurements in clinics and research","authors":"Carmen Streibel, C. Corin Willers, Grzegorz Bauman, Orso Pusterla, Oliver Bieri, Enno Stranzinger, Ben Brabandt, Marion Curdy, Yasmin Salem, Carmen Casaulta, Insa Korten, Sophie Yammine, Philipp Latzin, Elisabeth Kieninger","doi":"10.1183/13993003.congress-2023.pa3996","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa3996","url":null,"abstract":"Background: Structural and functional magnetic resonance imaging (MRI) of the lung is well suited for repeated measurements especially in children, as patients are not exposed to ionizing radiation. Matrix-Pencil decomposition (MP)-MRI is a highly promising approach allowing simultaneous assessment of lung ventilation and perfusion without the need of contrast agent, hyperpolarized gas and/or specific breathing maneuvers. Aim: To report our experience of seven years lung MP-MRI measurements in children. Methods: Since 2016 we performed more than 900 functional MP-MRI lung scans in children aged 5-18 years on a standard clinical 1.5 Tesla Siemens MRI scanner. Scans were used for both, study investigations and clinical questions, and were performed together with structural lung MRI measurements. Results: MP-MRI is easily feasible even in young children and of short duration (8 minutes on average). Outcome parameters like ventilation and perfusion defect percentage (VDP, QDP) and defect distribution index (DDI) are suited as study endpoints in lung diseases, e.g. cystic fibrosis, primary ciliary dyskinesia and congenital diaphragmatic hernia. In addition, MP-MRI is of help in clinical decision making, such as assessing the residual, local ventilation and perfusion after surgery for congenital airway malformation or necrotising pneumonia. Conclusions: We have pioneered the implementation of MP-MRI into clinics and shown that MP-MRI is applicable in various study settings. It helps guiding clinical decisions and is a promising tool for follow-up of chronic lung diseases providing spatially resolved information on functional deficits.","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136259963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multislice CT in the visualisation of thromboembolism of small branches of pulmonary arteries in COVID-19 多层螺旋CT在新冠肺炎患者肺动脉小分支血栓栓塞中的显像价值

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa3532

Elmira Chuvakova, Lina Zaripova, Timur Sarsengaliyev, Manana Peradze, Abay Baigenzhin

{"title":"Multislice CT in the visualisation of thromboembolism of small branches of pulmonary arteries in COVID-19","authors":"Elmira Chuvakova, Lina Zaripova, Timur Sarsengaliyev, Manana Peradze, Abay Baigenzhin","doi":"10.1183/13993003.congress-2023.pa3532","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa3532","url":null,"abstract":"Introduction: The identification of pulmonary thromboembolism (PTE) associated with COVID-19 requires careful diagnostic approach. Objective: to analyse the multislice CT (MSCT) data from patients with COVID-19. Methods: MSCT of 2,746 patients with COVID-19 was analysed, apart from them 112 patients with increased D-dimer underwent CT pulmonary angiography with post-processing analysis. In 14 patients the diagnosis was verified morphologically(autopsies). Results: CT pulmonary angiography revealed PTE in 45.9% of COVID-19 patients with elevated D-dimer. Indirect signs of PTE included: -areas of increased density, often triangular in shape (arrow, Fig.1A) and linear thickening (arrow, Fig.1B); -Westermarck9s symptom - local depletion of the lung pattern (arrow, Fig.1C) in three mutually perpendicular projections; -expansion of small branches of pulmonary arteries as signs of pulmonary hypertension (Fig.1D). Central and parietal emboli were visible in the lumen of the subsubsegmental and subsegmental arteries of the lungs (Fig.1E, F). The central embolus was surrounded by the contrast - a symptom of \"polo stamp\" (Fig.1G). Thrombus in the pulmonary artery was morphologically confirmed (Fig.1H, hematoxylin and eosin staining). Conclusions: CT pulmonary angiography allows revealing the acute thromboembolism of small branches of pulmonary artery and should be recommended in case of COVID-19 with elevated D-dimer level.","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136260113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Side-specific assessment of lung function in children with congenital diaphragmatic hernia - functional matrix pencil decomposition MRI as a promising diagnostic tool 先天性膈疝患儿肺功能的侧边特异性评估——功能性基质铅笔分解MRI作为一种有前景的诊断工具

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa3994

Carmen Streibel, C Corin Willers, Grzegorz Bauman, Orso Pusterla, Oliver Bieri, Marion Curdy, Matthias Horn, Carmen Casaulta, Steffen Berger, Gabriela Marta Dekany, Elisabeth Kieninger, Andreas Bartenstein, Philipp Latzin

{"title":"Side-specific assessment of lung function in children with congenital diaphragmatic hernia - functional matrix pencil decomposition MRI as a promising diagnostic tool","authors":"Carmen Streibel, C Corin Willers, Grzegorz Bauman, Orso Pusterla, Oliver Bieri, Marion Curdy, Matthias Horn, Carmen Casaulta, Steffen Berger, Gabriela Marta Dekany, Elisabeth Kieninger, Andreas Bartenstein, Philipp Latzin","doi":"10.1183/13993003.congress-2023.pa3994","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa3994","url":null,"abstract":"Objectives: In patients with congenital diaphragmatic hernia (CDH) the exact functional outcome of the affected lung side is still unknown, mainly due to the lack of spatially resolved diagnostic tools. Functional matrix-pencil decomposition (MP-) lung MRI fills this gap as it measures side-specific ventilation and perfusion. We aimed to assess the overall and side-specific pulmonary long-term outcome of patients with CDH using lung function tests and functional MP-MRI. Methods: Thirteen school aged children with CDH (seven with small and six with large defect-sized CDH, defined as >50% of the chest wall circumference being devoid of diaphragm tissue) and thirteen healthy matched controls underwent spirometry, multiple-breath washout and MP-MRI. Main outcomes were forced expiratory volume in 1 second (FEV1), lung clearance index (LCI), ventilation defect percentage (VDP), perfusion defect percentage (QDP). Results: Patients with a large CDH showed significantly reduced overall lung function compared to healthy controls [mean difference; 95%-CIadjusted.: FEV1 (z-score) -4.26 (-5.61 to -2.92), LCI2.5 (TO) 1.12 (0.47 to 1.76), VDP (%) 8.59 (3.58 to 13.60), QDP (%) 17.22 (13.16 to 21.27)] and to patients with a small CDH. Side-specific examination by MP-MRI revealed particularly reduced ipsilateral ventilation and perfusion in patients with a large CDH [mean difference to contralateral side; 95%-CIadjusted.: VDP (%) 14.80 (10.50 to 19.00), QDP (%) 23.50 (1.75 to 45.20)]. Conclusions: Patients with a large CDH showed impaired overall lung function with particular limitation of the ipsilateral side. MP-MRI is a promising tool to provide valuable side-specific functional information in the follow-up of patients with CDH.","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"369 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136260643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A missed opportunity - fibrosis on previous abdominal CTs in patients referred to an ILD clinic 一个错过的机会-以前的腹部ct纤维化患者转介到ILD诊所

Imaging Pub Date : 2023-09-09 DOI: 10.1183/13993003.congress-2023.pa4011

Jude Wellens-Mensah, Matthew Embley, Paul Cadden, Mudher Al-Khairalla, Peter Williamson, Mark Spears

{"title":"A missed opportunity - fibrosis on previous abdominal CTs in patients referred to an ILD clinic","authors":"Jude Wellens-Mensah, Matthew Embley, Paul Cadden, Mudher Al-Khairalla, Peter Williamson, Mark Spears","doi":"10.1183/13993003.congress-2023.pa4011","DOIUrl":"https://doi.org/10.1183/13993003.congress-2023.pa4011","url":null,"abstract":"Introduction: Early use of anti-fibrotic medication in pulmonary fibrosis protects lung function, prolonging quality of life. Increased use of CT could enable detection of disease before significant symptoms develop. The majority of CT scans are requested by primary care teams, general physicians or surgeons. However these groups are unfamiliar with the significance of classical descriptors for pulmonary fibrosis used by radiologists. A recent case (patient presented with disabling breathlessness requiring oxygen at diagnosis, a year after CT for cholecystitis) led us to audit our ILD clinic with the aim of determining local prevalence. Methods: 116 patient records at a University Clinic were reviewed, to ascertain the prevalence of CT abdomen scans prior to referral. In addition to reports with ’refer to respiratory’ we sought words commonly employed to describe fibrosing interstitial lung diseases (reticulation, honeycombing, ground glass). Findings 11 patients had abdominal CT scans before referral. 5 had fibrosis present. Time from these scans to clinic review ranged from 3 to 36 months. Only 2 reports recommended referral to the respiratory team. A further 2 contained descriptors but no guidance, and one report failed to describe the fibrosis. Reports recommending ’refer to respiratory’ were followed. Of the remaining three patients, all were referred by their GP following presentation with symptoms. Conclusions: Abdominal CTs could enable early referral to ILD clinics, but this opportunity is lost due to reporting habits. Clear guidance to requestors is followed and should be employed as standard. Radiology training and education should target this issue, to improve outcomes for patients.","PeriodicalId":34850,"journal":{"name":"Imaging","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136260884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging最新文献