AlKimiya Jurnal Ilmu Kimia dan Terapan最新文献

Synthesis, Characterization of Polyvinyl Alcohol-Chitosan-ZnO/CuO Nanoparticles Film and Its Biological Evaluation as An Antibacterial Agent of Staphylococcus aureus 聚乙烯醇-壳聚糖-氧化锌/氧化铜纳米膜的合成、表征及其对金黄色葡萄球菌抗菌性能的生物学评价

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-06-30 DOI: 10.15575/ak.v10i1.24725

A. Fatoni, Mauizatul Hasanah, Lasmaryna Sirumapea, Annisa Defanie Putri, Khoirunnisa Sari, Restu Dwi Khairani, N. Hidayati

{"title":"Synthesis, Characterization of Polyvinyl Alcohol-Chitosan-ZnO/CuO Nanoparticles Film and Its Biological Evaluation as An Antibacterial Agent of Staphylococcus aureus","authors":"A. Fatoni, Mauizatul Hasanah, Lasmaryna Sirumapea, Annisa Defanie Putri, Khoirunnisa Sari, Restu Dwi Khairani, N. Hidayati","doi":"10.15575/ak.v10i1.24725","DOIUrl":"https://doi.org/10.15575/ak.v10i1.24725","url":null,"abstract":"The polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film was researched. Synthesis, characterization, and its biological evaluation as an antibacterial of Staphylococcus aureus were the aims of this research. The biosynthesis of ZnO, CuO, and ZnO/CuO nanoparticles was done using the biological method. The polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film was synthesized using the casting method. All the products were characterized by FTIR spectroscopy, X-ray diffraction, and Scanning Electron Microscope (SEM). Polyvinyl alcohol-chitosan-ZnO/CuO nanoparticles film as a paper disk for the evaluation as an antibacterial agent through the agar disk diffusion method. The absorption bands of ZnO, CuO, and ZnO/CuO nanoparticles can be observed at 318, 274, and 252 nm, respectively. The peaks at wavenumbers 433-673 and 619 cm-1 were Zn-O and Cu-O groups, respectively. The Zn-O and Cu-O groups at ZnO/CuO nanoparticles can be observed at 474 and 619 cm-1. The appearance of Zn-O and Cu-O groups at film PVA-chitosan-ZnO/CuO nanoparticles indicates the wavenumber between 433 and 673 cm-1. The physical structure of ZnO, CuO, and ZnO/CuO nanoparticles is crystalline form. The crystallite size of ZnO, CuO, and ZnO/CuO nanoparticles was estimated at 1.0572, 6.6315, and 2.3333 nm respectively. The physical structure of film PVA-chitosan-ZnO/CuO nanoparticles is amorphous. The surface morphology of films C, D, and E was affected by the addition of chitosan and ZnO/CuO nanoparticles. The film of PVA-chitosan-ZnO/CuO nanoparticles (C, D and E) can act as an antibaterial agent of Staphylococcus aureus.The inhibition zone of film D is higher than A, B, C, and E.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46343663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Low Solid/Liquid Ratio on Hydrothermal Synthesis of Hydroxyapatite with Green Template from Banana Flower (Musa acuminata Cavendish) 低固液比对香蕉花绿色模板水热合成羟基磷灰石的影响

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-06-30 DOI: 10.15575/ak.v10i1.25262

F. S. Irwansyah, Alfi Ikhlasul Amal, E. P. Hadisantoso, A. Noviyanti, D. Eddy, Azman Ma'amor, Risdiana Risdiana

引用次数: 0

Studi of In Vivo Antidiabetic Activity of Namnam Leaves (Cynometra cauliflora) Extract in Sprague Dawley Rat 菊花叶提取物对Sprague-Dawley大鼠体内抗糖尿病活性的研究

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-06-30 DOI: 10.15575/ak.v10i1.23406

La Ode Sumarlin, A. Suprayogi, M. Rahminiwati, A. Satyaningtijas, H. Hajar, Meyliana Wulandari

{"title":"Studi of In Vivo Antidiabetic Activity of Namnam Leaves (Cynometra cauliflora) Extract in Sprague Dawley Rat","authors":"La Ode Sumarlin, A. Suprayogi, M. Rahminiwati, A. Satyaningtijas, H. Hajar, Meyliana Wulandari","doi":"10.15575/ak.v10i1.23406","DOIUrl":"https://doi.org/10.15575/ak.v10i1.23406","url":null,"abstract":"Various treatments for Type 2 Diabetes Mellitus (T2DM) aim to alleviate hyperglycemia. Although natural products have been extensively utilized, their mechanism of action and efficacy as antidiabetic agents, particularly for T2DM, has not been extensively assessed in vivo. In this research, the leaves of the Namnam (Cynometra cauliflora) were extracted and tested for their activity as an antidiabetic agent. Sprague Dawley rats aged 3.5-4 months, weighing 200-250 g, were used as the experimental model, with a total of 30 individuals. The rats were induced with a high-fat diet and 30% sucrose until their blood glucose concentration reached ≥ 120 mg/dL. Subsequently, the rats were divided into four groups (groups 1, 2, 3, and 4). Over 21 days, changes in blood glucose, triacylglycerol, glycogen, and blood plasma insulin levels were assessed. The results demonstrated that the methanol extract of Namnam leaves (NLME) effectively reduced blood glucose levels by 23-34%, decreased plasma triglyceride levels by 13-30%, and increased liver glycogen levels by 68-96% compared to the control group (Diabetes). Among all the parameters assessed, NLME exhibited similar performance to metformin, a commonly prescribed diabetes medication (p<0.05). Furthermore, the study revealed that NLME exerted antidiabetic effects, particularly for T2DM, by promoting liver glycogen formation, enhancing insulin secretion control, facilitating glucose absorption by muscles, and restricting fat metabolism in the blood","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43992987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silica Modified Natural Dye of Caesalpinnia sappan l. on Cotton Fabrics 二氧化硅改性天然染料在棉织物上的应用

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-06-30 DOI: 10.15575/ak.v10i1.24578

K. Budiasih, E. Rohaeti, Isti Yunita, A. Kamari

引用次数: 0

Characterization of Secondary Metabolites and Cytotoxic Assay of Haliclona sp. Sponge Against T47D Breast Cancer Cells Haliclona sp.海绵对T47D乳腺癌症细胞次级代谢产物的鉴定及细胞毒性测定

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-06-30 DOI: 10.15575/ak.v10i1.20334

A. Sapar, Millenia Millenia, A. B. Aritonang, R. Rudiyansyah, W. Rahmalia

{"title":"Characterization of Secondary Metabolites and Cytotoxic Assay of Haliclona sp. Sponge Against T47D Breast Cancer Cells","authors":"A. Sapar, Millenia Millenia, A. B. Aritonang, R. Rudiyansyah, W. Rahmalia","doi":"10.15575/ak.v10i1.20334","DOIUrl":"https://doi.org/10.15575/ak.v10i1.20334","url":null,"abstract":"Characterization of secondary metabolites and cytotoxic testing of Haliclona sp. against T47D breast cancer cells were conducted in this study. The objective was to assess the cytotoxicity of T47D cancer cells and identify the functional groups involved. The research methods employed included maceration, partitioning, phytochemical testing, toxicity testing using the BSLT method, separation through flash column chromatography (FCC), cytotoxic testing using the MTT method, and characterization using FTIR. The partition results of methanol extract consist of n-hexane, ethyl acetate, and methanol-water fractions. The methanol extract demonstrated high toxicity, with an LC50 of 5.21 ppm. Among the fractions, the ethyl acetate fraction exhibited the highest toxicity compared to the n-hexane and methanol-water fractions, with LC50 values of 25.76 ppm, 42.71 ppm, and 55.26 ppm, respectively. Phytochemical testing of the ethyl acetate fraction yielded positive results for terpenoids, steroids, alkaloids, and phenolic compounds. The ethyl acetate fraction was further separated using flash column chromatography, resulting in ten combined fractions (M1-M10). The cytotoxicity tests of the M3 fraction against 747D breast cancer cells showed non-toxic effects, with an IC50 value of 1382.29 ppm. The FTIR analysis of the M3 fraction revealed the presence of functional groups such as O-H, =C-H, C-H aliphatic, C=O, and C=C, which is indicative of the presence of terpenoids, steroids, and esters.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41378844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Characterization of 1-(1-naphthyl)-5-phenyl-2,4-pentadien-1-one from trans-cinnamaldehyde and 1-acetonaphthone 由反式肉桂醛和1-乙酰萘酮合成1-(1-萘基)-5-苯基-2,4-戊二烯-1- 1的表征

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-06-30 DOI: 10.15575/ak.v10i1.22896

Dori Fitria, B. Ardiansah, Atia Balkis

引用次数: 0

Degradation of Phenol Using Sonolysis and Photolysis by TiO2/RHAC Catalyst and Analysis with Spectrophotometer UV-VIS and HPLC TiO2/RHAC催化声裂解和光解降解苯酚及紫外-可见光谱和高效液相色谱分析

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-06-30 DOI: 10.15575/ak.v10i1.24775

Safni Safni, Eno Okta Patricia, Trisna Ollinovela, Yulizar Yusuf

{"title":"Degradation of Phenol Using Sonolysis and Photolysis by TiO2/RHAC Catalyst and Analysis with Spectrophotometer UV-VIS and HPLC","authors":"Safni Safni, Eno Okta Patricia, Trisna Ollinovela, Yulizar Yusuf","doi":"10.15575/ak.v10i1.24775","DOIUrl":"https://doi.org/10.15575/ak.v10i1.24775","url":null,"abstract":"This study focuses on the degradation of phenol in aqueous solutions using photolysis and sonolysis methods. It investigates the impact of catalyst mass, types of light (UV-A, UV-C, and visible light), types of catalyst (RHAC, TiO2, and TiO2/RHAC), and processing time on phenol degradation. The phenol solutions are analyzed before and after degradation using Spectrophotometer UV-Vis and HPLC. The research aims to understand the factors influencing phenol degradation and provide a basis for further studies to enhance the efficiency of phenol removal. Results show significant improvements in degradation percentages of phenol by using TiO2/RHAC as the catalyst. Sonolysis achieves a degradation of 20.82% with a catalyst, which increases to 50.57% with the catalyst. Photolysis achieves a degradation of 29.06%, which rises to 91.99% with the catalyst. The highest degradation percentage is achieved using UV-A light for 5 hours with a catalyst mass of 30 mg of TiO2/RHAC catalyst. HPLC analysis confirms a decreased phenol concentration and the presence of intermediate compounds. The TiO2/RHAC catalyst demonstrates the promising potential for efficient phenol degradation in aqueous solutions.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41489959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Variations of Hydrothermal Temperatures on Ex-Situ Hydroxyapatite/Al2O3 Doping Process from Papai Shrimp (Acetes erythraeus) 水热温度变化对木瓜虾原位掺杂羟基磷灰石/Al2O3过程的影响

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-01-01 DOI: 10.15575/ak.v9i2.20520

R. Bemis, R. D. Puspitasari, Heriyanti Heriyanti, R. Rahmi, Gessy Tri Priyanti

{"title":"The Effect of Variations of Hydrothermal Temperatures on Ex-Situ Hydroxyapatite/Al2O3 Doping Process from Papai Shrimp (Acetes erythraeus)","authors":"R. Bemis, R. D. Puspitasari, Heriyanti Heriyanti, R. Rahmi, Gessy Tri Priyanti","doi":"10.15575/ak.v9i2.20520","DOIUrl":"https://doi.org/10.15575/ak.v9i2.20520","url":null,"abstract":"Hydroxyapatite (HA) is an alloplastic material that is commonly used as a substitute for bone grafts or bone grafts because it has bioactive properties, namely osteoconduction. This study aims to improve or develop the function of hydroxyapatite to become a strong and resilient biological device that can withstand loads for appropriate functions such as bone implants. Therefore, it is necessary to modify the structure, among others, by the reinforcement process (composite formation) with other materials.The doping of hydroxyapatite/Al2O3 in this study was carried out using the hydrothermal method. The hydrothermal method is one of the hydroxyapatite synthesis methods carried out at high pressure and temperature to achieve equilibrium. The material used in this study was papai shrimp as a source of calcium. The temperature has an effect in this study where the higher the doping temperature used, the higher the degree of crystallinity, particle size homogeneity, and porosity value. From the doping results, it is known that a temperature of 300°C produces a degree of crystallinity of 54.32% and a crystal size of 3.75 nm with a porosity value of 99.38%. This result is much better than the undoped hydroxyapatite in the previous study.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49218858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sunscreen Activity Determination on Hippobroma Longiflora Leaves Extracts Affected to Differences in Simplicia Treatments and Extraction Techniques 不同处理方法及提取工艺对长叶海马叶提取物防晒活性的影响

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-01-01 DOI: 10.15575/ak.v9i2.20502

Awaly Ilham Dewantoro, S. Putri, E. Mardawati, Desy Nurliasari

{"title":"Sunscreen Activity Determination on Hippobroma Longiflora Leaves Extracts Affected to Differences in Simplicia Treatments and Extraction Techniques","authors":"Awaly Ilham Dewantoro, S. Putri, E. Mardawati, Desy Nurliasari","doi":"10.15575/ak.v9i2.20502","DOIUrl":"https://doi.org/10.15575/ak.v9i2.20502","url":null,"abstract":"Various weeds in paddy rice fields could be utilized as natural polyphenols sources, one of them was kitolod (Hippobroma longiflora (L.) G.Don). Kitolod was widely utilized as traditional medicine by several community groups because of its polyphenols content. Recent trends showed kitolod could be valorized as additive matters in sunscreen products. Polyphenols content, especially flavonoids were able to absorb dangerous spectrum in sunray radiation and it is related to sunscreen activity. This study aimed to evaluate the differences in simplicia treatments and extraction techniques towards total polyphenols content and sunscreen activity on kitolod leaf extracts. Solvent-cold extraction techniques were deployed in this study that consist of water infusion and ethanolic maceration for 24 hours at ambient temperature. Extracts were analyzed by spectrophotometric measurement to determine total phenolics content (TPC), total flavonoids content (TFC), and sunscreen activity by deploying Folin-Ciocalteu assay, AlCl3 colorimetric assay, and Mansur approached assay, respectively. Dry kitolod leaves were extracted by ethanolic maceration techniques provided high yields (15.5±0.3%), high TPC (17.9±0.3 mg GAE/g of solids), high TFC (25.9±0.4 mg QE/g of solids), and moderate sunscreen activity (SPF 11.0±0.1). The results indicated kitolod could be valorized as natural polyphenols sources and additive matters in any cosmetical sunscreen products.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43452334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Eceng Gondok Waste into Electrical Based on Microbial Fuel Cell 基于微生物燃料电池的电渣处理

AlKimiya Jurnal Ilmu Kimia dan Terapan Pub Date : 2023-01-01 DOI: 10.15575/ak.v9i2.20974

Hijrah Amaliah Azis, Ardiansa Ardiansa, Riki Kusuma Purnama

{"title":"Treatment of Eceng Gondok Waste into Electrical Based on Microbial Fuel Cell","authors":"Hijrah Amaliah Azis, Ardiansa Ardiansa, Riki Kusuma Purnama","doi":"10.15575/ak.v9i2.20974","DOIUrl":"https://doi.org/10.15575/ak.v9i2.20974","url":null,"abstract":"The increasing consumption of electrical energy and still dependent on non-renewable energy has encouraged the implementation of effective, efficient, and environmentally friendly technologies to produce electrical energy. Microbial Fuel Cell (MFC) is one of the alternative technologies that utilize microorganisms in converting chemical energy from organic compounds under anaerobic conditions to be converted into electrical energy. The study was conducted to determine the potential of electrical energy generated from the treatment of eceng gondok waste (Eichhornia crassipes) with variations in the addition of buffer solutions and combinations of electrolyte solutions using the microorganism Saccharomyces cerevisiae through Microbial Fuel Cell technology. This study consists of three stages and methods, namely sample preparation, MFC media preparation, and analysis of pH, current, voltage, and power density. Measurement of the value of the maximum voltage, maximum current and power density is carried out every 3 hours for 27 hours for each treatment. The results were obtained as follows consecutively: firstly, for variations without the addition of buffers and electrolyte solutions are 0.25 volts; 0.08 mA; 13.05 mW/m2, secondly, with buffer and electrolyte solution KMnO4 0.2 M are 1.12 volts; 0.77 mA; 562.92 mW/m2, and thirdly, with buffer and K3Fe(CN)6 0.2 M are 0.47 volts; 0.48 mA; 147.26 mW/m2. Based on the results of the study, it was concluded that the most optimal variation in producing electrical energy was in the variation in the addition of a phosphate buffer and 0.2 M KMnO4 solution. Eceng gondok waste has the potential to be used as a source of electrical energy.","PeriodicalId":34816,"journal":{"name":"AlKimiya Jurnal Ilmu Kimia dan Terapan","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42196847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1