Pau Federico Zaragoza, T. Castelló Viguer, Luis Martínez Ortiz de Urbina, Ana Planas del Viejo, E. Peris Domingo, F. Pomar Domingo
{"title":"Thermodilution assessment of vasoreactivity and microvascular function in the absence of obstructive coronary artery disease","authors":"Pau Federico Zaragoza, T. Castelló Viguer, Luis Martínez Ortiz de Urbina, Ana Planas del Viejo, E. Peris Domingo, F. Pomar Domingo","doi":"10.24875/recice.m23000376","DOIUrl":"https://doi.org/10.24875/recice.m23000376","url":null,"abstract":"Introduction and objectives: Invasive diagnosis of vasoreactivity and microvascular function may be useful to optimize the management of patients with signs and/or symptoms of myocardial ischemia in the absence of significant coronary stenosis (INOCA). We analyzed the prevalence of the different endotypes, as well as the concordance between 2 diagnostic methods based on ther-modilution assessment. Methods: We prospectively included 60 patients with INOCA who underwent a vasoreactivity test with intracoronary acetylcholine, and measurement of absolute coronary blood flow (Q) and minimum microvascular resistance (R) using continuous thermodilution assessment. Finally, calculations of the coronary flow reserve (CFR) and index of microcirculatory resistance index (IMR) were made using the bolus thermodilution method considering CFR < 2 and MRI ≥ 25 as established pathological cut-off values. Results: The invasive functional diagnostic procedure allowed patients to be categorized into 4 subgroups: microvascular dysfunction (40%), epicardial vasospasm (17%), mixed disorder (20%), and normal study (23%). No correlation was seen between the Q and the CFR. Using ROC curves, an R > 435 UW was estimated as the optimal cut-off value to identify patients with IMR ≥ 25 with an area under the curve of 0.67 (95%CI, 0.51-0.82; P = .04). Conclusions: The invasive study of vasoreactivity and microcirculation was feasible and safe. Prevalence of vasospasm and microvascular dysfunction in patients with INOCA was high. The CFR/MRI/Q combined study allowed us to unmask a subtype of microvascular dysfunction characterized by an abnormally high coronary flow at baseline. The concordance seen between the microvascular resistance obtained by continuous thermodilution measurements and the reference method was low so future studies are justified to determine the usefulness of this technique.","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42139422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcel Alméndarez, Rut Álvarez-Velasco, Alberto Alperi Garcia, P. Avanzas, Cesar Morís de la Tassa, and Isaac Pascual
{"title":"Drug-eluting balloon angioplasty for bifurcated chronic total coronary occlusion","authors":"Marcel Alméndarez, Rut Álvarez-Velasco, Alberto Alperi Garcia, P. Avanzas, Cesar Morís de la Tassa, and Isaac Pascual","doi":"10.24875/recice.m23000390","DOIUrl":"https://doi.org/10.24875/recice.m23000390","url":null,"abstract":"This is the case of a 67-year-old woman admitted due to a 6-month history of exertional angina. Stress echocardiography showed severe anterior wall ischemia. The patient was referred for coronary angiography that revealed the presence of a chronic total coronary occlusion of the proximal left anterior descending coronary artery (LAD) immediately before the bifurcation with the first diagonal branch (D1) from the septal collaterals of the right coronary artery (figure 1A, video 1 of the supplementary data). The patient signed the written informed consent, and a chronic total coronary occlusion recanalization was performed 6 months after the index angiography.","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42016783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Jurado-Román, A. Gómez-Menchero, I. Amat-Santos, J. Caballero-Borrego, S. Ojeda, R. Ocaranza-Sanchez, S. Jiménez-Valero, G. Galeote, and Raúl Moreno
{"title":"Design of the ROLLERCOASTR trial: rotational atherectomy, lithotripsy or laser for the management of calcified coronary stenosis","authors":"A. Jurado-Román, A. Gómez-Menchero, I. Amat-Santos, J. Caballero-Borrego, S. Ojeda, R. Ocaranza-Sanchez, S. Jiménez-Valero, G. Galeote, and Raúl Moreno","doi":"10.24875/recice.m23000381","DOIUrl":"https://doi.org/10.24875/recice.m23000381","url":null,"abstract":"Introduction and objectives: Coronary calcification is one of the leading factors that affect negatively the safety and effectiveness of percutaneous coronary intervention. Several calcium modification techniques exist. However, there is a lack of randomized evidence on the therapy of choice in this scenario. Methods: The ROLLERCOASTR is a prospective, multicenter, randomized clinical trial designed to compare the safety and efficacy profile of 3 plaque modification techniques in the moderate-to-severe coronary calcification setting: rotational atherectomy (RA), excimer laser coronary angioplasty (ELCA), and intravascular lithotripsy (IVL). The study primary endpoint is stent expansion evaluated by optical coherence tomography. An intention-to-treat analysis will be conducted with an alpha coefficient of 0.05 between the reference group (RA) and the remaining 2 groups (ELCA and IVL). An analysis of the study primary endpoint per protocol will be conducted for consistency purposes. If the non-inferiority hypothesis is confirmed, a superiority 2-sided analysis will be conducted. Both the clinical events committee and the independent core laboratory will be blinded to the treatment arm. Assuming an α error of 0.05, an β error of 0.2 (80% power), a margin of irrelevance ( ε ) of 7, and losses of 10% due to measurement difficulty or impossibility to complete the intervention, we estimate a sample size of 56 cases per group. The study secondary endpoints are device success, procedural success, crossover rate among the different techniques used, and the occurrence of major adverse cardiovascular events at 1-year follow-up. Conclusions: The ROLLERCOASTR trial will evaluate and compare the safety and effectiveness of 3 plaque modification techniques: RA, ELCA, and IVL in patients with calcified coronary stenosis. This trial was registered at clinicaltrials.gov with identifier NCT04181268.","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42839683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Santos-Martínez, Miguel Leiva-Gordillo, R. García-Belenguer, Paula Tejedor-Viñuela, and Pedro Morillas-Blasco
{"title":"The mystery of the Dragon�s tail solved by 3D reconstruction","authors":"S. Santos-Martínez, Miguel Leiva-Gordillo, R. García-Belenguer, Paula Tejedor-Viñuela, and Pedro Morillas-Blasco","doi":"10.24875/recice.m23000385","DOIUrl":"https://doi.org/10.24875/recice.m23000385","url":null,"abstract":"","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44170790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Tamargo, J. Elízaga, and Francisco Fernández-Avilés
{"title":"Transcatheter closure of aorto-left atrial fistula","authors":"M. Tamargo, J. Elízaga, and Francisco Fernández-Avilés","doi":"10.24875/recice.m23000387","DOIUrl":"https://doi.org/10.24875/recice.m23000387","url":null,"abstract":"1. Mamas MA, Fraser DG, Ratib K, et al. Minimising radial injury: prevention is better than cure. EuroIntervention. 2014;10:824-832. 2. Hausenloy DJ, Kharbanda RK, Møller UK, et al. Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial. Lancet. 2019;394(10207):1415-1424. 3. Kume T, Akasaka T, Kawamoto T, et al. Assessment of coronary intimamedia thickness by optical coherence tomography: comparison with intravascular ultrasound. Circ J. 2005;69:903-907. 4. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74:1124-1136.","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44242759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Syphilitic aortitis as a rare cause of coronary ostial stenosis","authors":"Rui Flores, F. Mané, C. Braga, and Cátia Oliveira","doi":"10.24875/recice.m23000375","DOIUrl":"https://doi.org/10.24875/recice.m23000375","url":null,"abstract":"1. Woo EJ, Ogilvie RA, Krueger VS, Lundin M, Williams DM. Iliac vein compression syndrome from anterior perforation of a pedicle screw. J Surg Case Rep. 2016;2016:rjw003. 2. Cannon KA, Badiee J, Wallace JD, et al. The prevalence of chronic deep venous thrombosis in trauma: Implications for hospitals and patients. J Trauma Acute Care Surg. 2018;84:170-174. 3. Galea R, Roten L, Siontis GCM, Brugger N, Windecker S, Räber L. Percutaneous left atrial appendage closure with superior vascular access. EuroIntervention. 2022;18:e695-e696. 4. Zare P, Rechani L, Smithson S. Left atrial appendage closure device implantation via transhepatic vascular access: a case report. Eur Heart J Case Rep. 2020;4:1-5. CONFLICTS OF INTEREST","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48127276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofia Martinho, E. Jorge, V. Marinho, R. Baptista, Marco Costa, and Lino Gonçalves
{"title":"The MANTA vascular closure device in transfemoral TAVI: a real-world cohort","authors":"Sofia Martinho, E. Jorge, V. Marinho, R. Baptista, Marco Costa, and Lino Gonçalves","doi":"10.24875/recice.m23000380","DOIUrl":"https://doi.org/10.24875/recice.m23000380","url":null,"abstract":"Introduction and objectives: Transcatheter aortic valve implantation (TAVI) is an established treatment option for patients with symptomatic severe aortic stenosis often performed via transfemoral access route (TF-TAVI). Therefore, successful closure of large-bore access sites is essential. This study aims to investigate the safety and effectiveness of the MANTA (Teleflex/Essential Medical, United States) vascular closure device (VCD) in patients undergoing TF-TAVI in an unselected and consecutive cohort of patients. Methods: We conducted a single-center, observational study of 245 consecutive patients undergoing TF-TAVI in whom the arterial large-bore femoral access was closed with a MANTA device from March 2020 through February 2022. The primary efficacy outcome measure was the rate of VCD failure according to the VARC-3 definition. Results: Successful closure of the large-bore access site occurred in 92.2% of the patients (n = 226). According to the VARC-3 definition, no major vascular or bleeding complications related to the plug-based VCD were reported. Patients with failed VCDs (7.8%) had significantly smaller minimal femoral artery diameters (6.6 ± 1.1 mm vs 7.6 ± 1.4 mm; P = .005) and consequently, significant higher sheath-to-femoral artery diameter ratios (0.78 ± 0.16 vs 0.69 ± 0.15; P = .019). No other inter-group differences were found. Conclusions: In this single-center, real-world, unselected large cohort of consecutive patients treated with TF-TAVI, a plug-based VCD for large-bore arteriotomy closure turned out effective and safe, and enabled arterial access-site management with a low rate of complications.","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42463556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rui Flores, João Costa, Carlos Braga, Catarina Vieira, and, Catarina Quina-Rodrigues
{"title":"Intracoronary fibrinolysis as a bailout strategy for massive thrombotic catastrophe. Case resolution","authors":"Rui Flores, João Costa, Carlos Braga, Catarina Vieira, and, Catarina Quina-Rodrigues","doi":"10.24875/recice.m22000306","DOIUrl":"https://doi.org/10.24875/recice.m22000306","url":null,"abstract":"","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135572696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. M. T. Torre Hernández, Gabriela Veiga Fernández, S. Barrera, Fermín Sainz Laso, Daehyun Lee, and Tamara García Camarero
{"title":"New TAVI technique for difficult valve crossing","authors":"J. M. T. Torre Hernández, Gabriela Veiga Fernández, S. Barrera, Fermín Sainz Laso, Daehyun Lee, and Tamara García Camarero","doi":"10.24875/recice.m23000379","DOIUrl":"https://doi.org/10.24875/recice.m23000379","url":null,"abstract":",","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44370192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Rueda Núñez, C. Abelleira Pardeiro, B. Insa Albert, M. Álvarez-Fuente, Vanesa Balboa Barreiro, F. Ballesteros Tejerizo, P. Betrián-Blasco, Félix Coserría Sánchez, Juana María Espín López, Luis Fernández González, Dolores Herrera Linde, M. R. Romero Moreno, F. Sarnago Cebada, R. Sanz-Ruiz, and Juan Ignacio Zabala Argüelles
{"title":"Dosimetric parameters in congenital cardiac catheterizations in Spain: the GTH-SECPCC Radcong-21 multicenter registry","authors":"F. Rueda Núñez, C. Abelleira Pardeiro, B. Insa Albert, M. Álvarez-Fuente, Vanesa Balboa Barreiro, F. Ballesteros Tejerizo, P. Betrián-Blasco, Félix Coserría Sánchez, Juana María Espín López, Luis Fernández González, Dolores Herrera Linde, M. R. Romero Moreno, F. Sarnago Cebada, R. Sanz-Ruiz, and Juan Ignacio Zabala Argüelles","doi":"10.24875/recice.m23000372","DOIUrl":"https://doi.org/10.24875/recice.m23000372","url":null,"abstract":"Introduction and objectives: The results of the Radcong-21 Registry of the Spanish Society of Pediatric Cardiology and Congenital Heart Disease Working Group on Hemodynamics are described to analyze data, establish updated reference parameters, and compare them to other registries. Methods: Retrospective, cross-sectional, observational, multicenter registry of patients with congenital heart disease undergoing cardiac catheterization in 2021. Each cath lab sent the last 100 cases performed prior to January 2022. A descriptive analysis was conducted of anthropomorphic variables, procedural (grouped by type and radiation exposure categories [REC]) and technical characteristics, and dosimetric parameters with additional review of all values outside the 95%CI of the median. Results: A total of 1090 procedures performed in 11 cath lab of 10 hospital centers were analyzed. Age distribution: 22.8% < 1 year, 60.7% between 1-18 years, and 16.4% > 18 years. In dose area product (DAP)/Kg and DAP/Kg/fluoroscopy, the distribution was very similar regardless of the type of cath lab as is the case with most pediatric patients in terms of age, weight, and REC group. The DAP/Kg was higher in the REC I and III groups compared to other countries with registries and improvement programs in this area (78% and 8,3%, respectively). Conclusions: Representative data of dosimetric parameters by age and procedures in congenital cardiac catheterizations were obtained in Spain back in 2021. DAP/Kg is the parameter with the lowest dispersion in the sample. There is room for improvement compared to other countries with optimization programs in this area.","PeriodicalId":34613,"journal":{"name":"REC Interventional Cardiology English Ed","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47454216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}