Journal of Chest Surgery最新文献

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Debranch-First Technique with Zone 0 Elephant Trunk for Redo Operation of Residual Type B Aortic Dissection: The Completion of Aortic Proximalization. 0区象鼻先去分支技术用于残余B型主动脉夹层重做手术:完成主动脉近端化。
Journal of Chest Surgery Pub Date : 2024-01-05 Epub Date: 2023-11-23 DOI: 10.5090/jcs.23.084
Yoshito Inoue
{"title":"Debranch-First Technique with Zone 0 Elephant Trunk for Redo Operation of Residual Type B Aortic Dissection: The Completion of Aortic Proximalization.","authors":"Yoshito Inoue","doi":"10.5090/jcs.23.084","DOIUrl":"10.5090/jcs.23.084","url":null,"abstract":"<p><p>This article presents a straightforward hybrid arch technique for treating residual type B aortic dissecting aneurysms following type A repair (replacement of the ascending aorta) that employs a frozen elephant trunk (FET) straight vascular prosthesis. The debranch-first method involves only cutting and sewing the previous ascending graft, inserting the FET from zone 0, and debranching the arch vessels using a trifurcated graft. This technique is less invasive as it eliminates the need to manipulate the dissected distal arch aneurysm. We successfully applied this technique to 3 patients, with no instances of in-hospital death, stroke, or paraplegia. The debranch-first technique, combined with zone-0 FET insertion, simplifies the redo repair of residual type B aortic dissection.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138296088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Management of Coronary Artery Fistulas in Children. 儿童冠状动脉瘘的手术治疗。
Journal of Chest Surgery Pub Date : 2024-01-05 DOI: 10.5090/jcs.23.101
Youngkwan Song, Eun Seok Choi, Dong-Hee Kim, Bo Sang Kwon, Chun Soo Park, Tae-Jin Yun
{"title":"Surgical Management of Coronary Artery Fistulas in Children.","authors":"Youngkwan Song, Eun Seok Choi, Dong-Hee Kim, Bo Sang Kwon, Chun Soo Park, Tae-Jin Yun","doi":"10.5090/jcs.23.101","DOIUrl":"10.5090/jcs.23.101","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the surgical outcomes associated with coronary artery fistulas (CAFs) in children.</p><p><strong>Methods: </strong>We retrospectively reviewed the medical records of 23 pediatric patients who underwent surgical closure of CAFs between 1995 and 2021. At presentation, 7 patients (30.4%) exhibited symptoms. Associated cardiac anomalies were present in 8 patients. Fourteen fistulas originated from the right coronary artery and 9 from the left. The most common drainage site was the right ventricle, followed by the right atrium and the left ventricle. The median follow-up duration was 9.3 years (range, 0.1-25.6 years).</p><p><strong>Results: </strong>The median age and body weight at repair were 3.1 years (range, 0-13.4 years) and 14.4 kg (range, 3.1-42.2 kg), respectively. Cardiopulmonary bypass was used in 17 cases (73.9%), while cardioplegic arrest was employed in 14 (60.9%). Epicardial CAF ligation was utilized in 10 patients (43.5%), the transcoronary approach in 9 (39.1%), the endocardial approach in 2 (8.7%), and other methods in 2 patients (8.7%). The application of cardioplegic arrest during repair did not significantly impact the duration of postoperative intensive care unit stay or overall hospital stay. One in-hospital death and 1 late death were recorded. The overall survival rate was 95.7% at 10 years and 83.7% at 15 years. A residual fistula was detected in 1 patient. During the follow-up period, no surviving patient experienced cardiovascular symptoms or coronary events.</p><p><strong>Conclusion: </strong>Surgical repair of CAF can be performed safely with or without cardioplegic arrest, and it is associated with a favorable prognosis in children.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Experience of Surgical Treatment for Penetrating Pulmonary Gunshot Wound of a Civilian in Korea: A Case Report. 韩国平民穿透性肺枪伤手术治疗的临床经验:病例报告。
Journal of Chest Surgery Pub Date : 2024-01-05 Epub Date: 2023-08-14 DOI: 10.5090/jcs.23.061
Seonyeong Heo, Jung Hee Kim, Younggi Jung, Kwanghyoung Lee, Sungho Lee, Eunjue Yi
{"title":"Clinical Experience of Surgical Treatment for Penetrating Pulmonary Gunshot Wound of a Civilian in Korea: A Case Report.","authors":"Seonyeong Heo, Jung Hee Kim, Younggi Jung, Kwanghyoung Lee, Sungho Lee, Eunjue Yi","doi":"10.5090/jcs.23.061","DOIUrl":"10.5090/jcs.23.061","url":null,"abstract":"<p><p>Gunshot-induced chest trauma is exceedingly rare among civilians in South Korea due to strong firearm control policies. In contrast to military reports emphasizing the use of emergent open thoracotomy to increase chances of survival, most penetrating non-cardiac injuries in civilian settings are managed conservatively, such as through chest tube insertion, as they typically result from lower-energy bullets. However, early surgical intervention for penetrating gunshot wounds can help reduce delayed fatalities caused by septic complications from pneumonia or empyema. The advent of minimally invasive thoracic surgery has provided cost-effective and relatively non-invasive treatment options, aided in the prevention of potential complications from undrained hematomas, and facilitated functional recovery and reintegration into society. We successfully treated a patient with a penetrating gunshot wound to the chest using video-assisted thoracoscopic surgery.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10044372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Extracorporeal Membrane Oxygenation in COVID-19: A Single-Center Study. 体外膜氧合治疗COVID-19的结果:单中心研究
Journal of Chest Surgery Pub Date : 2024-01-05 Epub Date: 2023-12-07 DOI: 10.5090/jcs.23.102
Sahri Kim, Jung Hyun Lim, Ho Hyun Ko, Hong Kyu Lee, Yong Joon Ra, Kunil Kim, Hyoung Soo Kim
{"title":"Outcomes of Extracorporeal Membrane Oxygenation in COVID-19: A Single-Center Study.","authors":"Sahri Kim, Jung Hyun Lim, Ho Hyun Ko, Hong Kyu Lee, Yong Joon Ra, Kunil Kim, Hyoung Soo Kim","doi":"10.5090/jcs.23.102","DOIUrl":"10.5090/jcs.23.102","url":null,"abstract":"<p><strong>Background: </strong>Coronavirus disease 2019 (COVID-19) can lead to acute respiratory failure, which frequently necessitates invasive mechanical ventilation and extracorporeal membrane oxygenation (ECMO). However, the limited availability of ECMO resources poses challenges to patient selection and associated decision-making. Consequently, this retrospective single-center study was undertaken to evaluate the characteristics and clinical outcomes of patients with COVID-19 receiving ECMO.</p><p><strong>Methods: </strong>Between March 2020 and July 2022, 65 patients with COVID-19 were treated with ECMO and were subsequently reviewed. Patient demographics, laboratory data, and clinical outcomes were examined, and statistical analyses were performed to identify risk factors associated with mortality.</p><p><strong>Results: </strong>Of the patients studied, 15 (23.1%) survived and were discharged from the hospital, while 50 (76.9%) died during their hospitalization. The survival group had a significantly lower median age, at 52 years (interquartile range [IQR], 47.5-61.5 years), compared to 64 years (IQR, 60.0-68.0 years) among mortality group (p=0.016). However, no significant differences were observed in other underlying conditions or in factors related to intervention timing. Multivariable analysis revealed that the requirement of a change in ECMO mode (odds ratio [OR], 366.77; 95% confidence interval [CI], 1.92-69911.92; p=0.0275) and the initiation of continuous renal replacement therapy (CRRT) (OR, 139.15; 95% CI, 1.95-9,910.14; p=0.0233) were independent predictors of mortality.</p><p><strong>Conclusion: </strong>Changes in ECMO mode and the initiation of CRRT during management were associated with mortality in patients with COVID-19 who were supported by ECMO. Patients exhibiting these factors require careful monitoring due to the potential for adverse outcomes.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COR-KNOT-Induced Leaflet Perforation: How It Happens and How to Prevent It: A Case Report. COR KNOT诱导的小叶穿孔:如何发生和如何预防:一例报告。
Journal of Chest Surgery Pub Date : 2024-01-05 Epub Date: 2023-11-06 DOI: 10.5090/jcs.23.076
Michael Salna, Jack Shanewise, Alex D'Angelo, Isaac George
{"title":"COR-KNOT-Induced Leaflet Perforation: How It Happens and How to Prevent It: A Case Report.","authors":"Michael Salna, Jack Shanewise, Alex D'Angelo, Isaac George","doi":"10.5090/jcs.23.076","DOIUrl":"10.5090/jcs.23.076","url":null,"abstract":"<p><p>The COR-KNOT suture fastening device has dramatically improved the efficiency of valve suture fixation. Despite its relative ease of use, there are important considerations in deployment to limit the risk of prosthetic valve injury. Herein, we report a case of iatrogenic aortic bioprosthetic insufficiency caused by poorly positioned COR-KNOTs and outline technical strategies to ensure success.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2023 KASNet Guidelines on Atrial Fibrillation Surgery. 2023 KASNet心房颤动手术指南。
Journal of Chest Surgery Pub Date : 2024-01-05 Epub Date: 2023-11-23 DOI: 10.5090/jcs.23.127
Hyung Gon Je, Jae Woong Choi, Ho Young Hwang, Ho Jin Kim, Joon Bum Kim, Hee-Jung Kim, Jae-Sung Choi, Dong Seop Jeong, Jae Gun Kwak, Han Ki Park, Seung Hyun Lee, Cheong Lim, Jae Won Lee
{"title":"2023 KASNet Guidelines on Atrial Fibrillation Surgery.","authors":"Hyung Gon Je, Jae Woong Choi, Ho Young Hwang, Ho Jin Kim, Joon Bum Kim, Hee-Jung Kim, Jae-Sung Choi, Dong Seop Jeong, Jae Gun Kwak, Han Ki Park, Seung Hyun Lee, Cheong Lim, Jae Won Lee","doi":"10.5090/jcs.23.127","DOIUrl":"10.5090/jcs.23.127","url":null,"abstract":"","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138296175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Outcomes of Colon Conduits in Surgery for Primary Esophageal Cancer: A Propensity Score-Matched Comparison to Gastric Conduits. 原发性食管癌手术中结肠导管的长期疗效:与胃导管的倾向得分匹配比较。
Journal of Chest Surgery Pub Date : 2024-01-05 DOI: 10.5090/jcs.23.074
Jae Hoon Kim, Jae Kwang Yun, Chan Wook Kim, Hyeong Ryul Kim, Yong-Hee Kim
{"title":"Long-Term Outcomes of Colon Conduits in Surgery for Primary Esophageal Cancer: A Propensity Score-Matched Comparison to Gastric Conduits.","authors":"Jae Hoon Kim, Jae Kwang Yun, Chan Wook Kim, Hyeong Ryul Kim, Yong-Hee Kim","doi":"10.5090/jcs.23.074","DOIUrl":"10.5090/jcs.23.074","url":null,"abstract":"<p><strong>Background: </strong>In the treatment of esophageal cancer, a gastric conduit is typically the first choice. However, when the stomach is not a viable option, the usual alternative is a colon conduit. This study compared the long-term surgical outcomes of gastric and colon conduits over the same interval and aimed to identify factors influencing the prognosis.</p><p><strong>Methods: </strong>A retrospective review was conducted of patients who underwent esophagectomy followed by reconstruction for primary esophageal cancer between January 2006 and December 2020.</p><p><strong>Results: </strong>The study included 1,545 patients, with a gastric conduit used for 1,429 (92.5%) and a colon conduit for 116 (7.5%). Using propensity-matched analysis, 116 patients were selected from each group for comparison. No significant difference was observed in long-term survival between the gastric and colon conduit groups, irrespective of anastomosis level and pathological stage. A higher proportion of patients in the colon conduit group experienced postoperative complications compared to the gastric conduit group (57.8% vs. 25%, p<0.001). Multivariable analysis revealed that age over 65 years, body mass index below 22.0 kg/m<sup>2</sup>, neoadjuvant therapy, postoperative anastomotic leakage, and renal failure were risk factors for overall survival in patients with a colon conduit. Regarding conduit-related complications, cervical anastomosis was the only significant risk factor among those with a colon conduit.</p><p><strong>Conclusion: </strong>Despite the association of colon conduits with high morbidity rates relative to gastric conduits, the long-term outcomes of colon conduits were acceptable. More consideration should be given perioperatively to the use of a colon conduit, particularly in cases involving cervical anastomosis.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes after Biventricular Repair Using a Conduit between the Right Ventricle and Pulmonary Artery in Infancy. 在婴儿期使用右心室和肺动脉之间的导管进行双心室修复后的效果。
Journal of Chest Surgery Pub Date : 2024-01-05 DOI: 10.5090/jcs.23.107
Dong Hee Jang, Dong-Hee Kim, Eun Seok Choi, Tae-Jin Yun, Chun Soo Park
{"title":"Outcomes after Biventricular Repair Using a Conduit between the Right Ventricle and Pulmonary Artery in Infancy.","authors":"Dong Hee Jang, Dong-Hee Kim, Eun Seok Choi, Tae-Jin Yun, Chun Soo Park","doi":"10.5090/jcs.23.107","DOIUrl":"10.5090/jcs.23.107","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the outcomes of biventricular repair using right ventricle to pulmonary artery (RV-PA) conduit placement in patients aged <1 year.</p><p><strong>Methods: </strong>Patients aged <1 year who underwent biventricular repair using an RV-PA conduit between 2011 and 2020 were included in this study. The outcomes of interest were death from any cause, conduit reintervention, and conduit dysfunction (peak velocity of ≥3.5 m/sec or moderate or severe regurgitation).</p><p><strong>Results: </strong>In total, 141 patients were enrolled. The median age at initial conduit implantation was 6 months. The median conduit diameter z-score was 1.3. The overall 5-year survival rate was 89.6%. In the multivariable analysis, younger age (p=0.006) and longer cardiopulmonary bypass time (p=0.001) were risk factors for overall mortality. During follow-up, 61 patients required conduit reintervention, and conduit dysfunction occurred in 68 patients. The 5-year freedom from conduit reintervention and dysfunction rates were 52.9% and 45.9%, respectively. In the multivariable analysis, a smaller conduit z-score (p<0.001) was a shared risk factor for both conduit reintervention and dysfunction. Analysis of variance demonstrated a nonlinear relationship between the conduit z-score and conduit reintervention or dysfunction. The hazard ratio was lowest in patients with a conduit z-score of 1.3 for reintervention and a conduit z-score of 1.4 for dysfunction.</p><p><strong>Conclusion: </strong>RV-PA conduit placement can be safely performed in infants. A significant number of patients required conduit reintervention and had conduit dysfunction. A slightly oversized conduit with a z-score of 1.3 may reduce the risk of conduit reintervention or dysfunction.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Outcomes of Cervical Esophageal Cancer: A Single-Center Experience. 宫颈食管癌的手术效果:单中心经验
Journal of Chest Surgery Pub Date : 2024-01-05 DOI: 10.5090/jcs.23.085
Yoonseo Lee, Jeonghee Yun, Yeong Jeong Jeon, Junghee Lee, Seong Yong Park, Jong Ho Cho, Hong Kwan Kim, Yong Soo Choi, Young Mog Shim
{"title":"Surgical Outcomes of Cervical Esophageal Cancer: A Single-Center Experience.","authors":"Yoonseo Lee, Jeonghee Yun, Yeong Jeong Jeon, Junghee Lee, Seong Yong Park, Jong Ho Cho, Hong Kwan Kim, Yong Soo Choi, Young Mog Shim","doi":"10.5090/jcs.23.085","DOIUrl":"10.5090/jcs.23.085","url":null,"abstract":"<p><strong>Background: </strong>Cervical esophageal cancer is a rare malignancy that requires specialized care. While definitive chemoradiation is the standard treatment approach, surgery remains a valuable option for certain patients. This study examined the surgical outcomes of patients with cervical esophageal cancer.</p><p><strong>Methods: </strong>The study involved a retrospective review and analysis of 24 patients with cervical esophageal cancer. These patients underwent surgical resection between September 1994 and December 2018.</p><p><strong>Results: </strong>The mean age of the patients was 61.0±10.2 years, and 22 (91.7%) of them were male. Furthermore, 21 patients (87.5%) had T3 or T4 tumors, and 11 (45.8%) exhibited lymph node metastasis. Gastric pull-up with esophagectomy was performed for 19 patients (79.2%), while 5 (20.8%) underwent free jejunal graft with cervical esophagectomy. The 30-day operative mortality rate was 8.3%. During the follow-up period, complications included leakage at the anastomotic site in 9 cases (37.5%) and graft necrosis of the gastric conduit in 1 case. Progression to oral feeding was achieved in 20 patients (83.3%). Fifteen patients (62.5%) displayed tumor recurrence. The median time from surgery to recurrence was 10.5 months, and the 1-year recurrence rate was 73.3%. The 1-year and 3-year survival rates were 75% and 33.3%, respectively, with a median survival period of 17 months.</p><p><strong>Conclusion: </strong>Patients with cervical esophageal cancer who underwent surgical resection faced unfavorable outcomes and relatively poor survival. The selection of cases and decision to proceed with surgery should be made cautiously, considering the risk of severe complications.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prothrombin Complex Concentrate versus Fresh Frozen Plasma in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis. 凝血酶原复合物浓缩物与新鲜冷冻血浆在接受心脏手术的成人患者中的应用:一项系统综述和荟萃分析。
Journal of Chest Surgery Pub Date : 2024-01-05 Epub Date: 2023-11-23 DOI: 10.5090/jcs.23.081
Patricia Viana, Jessica Hoffmann Relvas, Marina Persson, Thamiris Dias Delfino Cabral, Jorge Eduardo Persson, Jessica Sales de Oliveira, Paulo Bonow, Camila Veronica Souza Freire, Sara Amaral
{"title":"Prothrombin Complex Concentrate versus Fresh Frozen Plasma in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis.","authors":"Patricia Viana, Jessica Hoffmann Relvas, Marina Persson, Thamiris Dias Delfino Cabral, Jorge Eduardo Persson, Jessica Sales de Oliveira, Paulo Bonow, Camila Veronica Souza Freire, Sara Amaral","doi":"10.5090/jcs.23.081","DOIUrl":"10.5090/jcs.23.081","url":null,"abstract":"<p><strong>Background: </strong>Prothrombin complex concentrate (PCC) and fresh frozen plasma (FFP) are commonly used to manage bleeding in patients during cardiac surgery. However, the relative efficacy and safety of these 2 strategies remain uncertain.</p><p><strong>Methods: </strong>MEDLINE, Embase, and Cochrane were searched for studies comparing PCC and FFP in patients who underwent cardiac surgery complicated by bleeding. Review Manager (RevMan) ver. 5.4 (Nordic Cochrane Centre, The Cochrane Collaboration) was used for statistical analysis. Binary and continuous outcomes were compared using pooled risk ratios and mean differences, respectively. The meta-analysis protocol was registered in the International Prospective Register of Systematic Reviews under protocol number CRD42022379144.</p><p><strong>Results: </strong>We included 8 studies with 1,500 patients, of whom 613 (40.9%) received PCC. The mean follow-up period ranged from 28 to 90 days. The PCC group had significantly lower chest tube drainage at 24 hours (mean difference [MD], -148.50 mL; 95% CI, -253.02 to -43.99 mL; p=0.005; I<sup>2</sup>=42%). Fewer units of red blood cells (RBCs) were transfused within the first 24 hours (MD, -1.02 units; 95% CI, -1.81 to -0.24 units; p=0.01; I<sup>2</sup>=56%), and fewer patients required RBC transfusion within the first 24 hours (risk ratio, 0.85; 95% CI, 0.78-0.93; p<0.007; I<sup>2</sup>=45%) in the PCC group. There were no statistically significant differences in secondary outcomes. Nonetheless, a subgroup analysis of randomized controlled trials failed to corroborate the results obtained from the main analysis.</p><p><strong>Conclusion: </strong>Our findings suggest that PCC can be effective, without increased adverse events, when compared with FFP in patients undergoing cardiac surgery complicated by bleeding.</p>","PeriodicalId":34499,"journal":{"name":"Journal of Chest Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10792384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138296089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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