Reports in Clinical Studies and Medicine最新文献

{"title":"Clinical and laboratory evaluation of patients afflicted with allergic asthma under immunotherapy","authors":"Falah Hasasn Hade","doi":"10.18282/rcsm.v2.i1.714","DOIUrl":"https://doi.org/10.18282/rcsm.v2.i1.714","url":null,"abstract":"<p align=\"justify\"><strong>Background</strong>: Allergy may be defined as a constellation of signs and symptoms in which the altered immunologic reaction between foreign substance (allergens) and antibodies resulting in pathologic reactions referred as allergic reactions.</p><p align=\"justify\">Allergic asthma is well known type 1- allergic reaction Up to 30% of general population suffers from various form of this malady during normal life span .</p><p align=\"justify\"><strong>Objective:</strong> To evaluate the effects of immunotherapy on groups of Iraqi people afflicted with allergic asthma through some clinical and laboratories tests</p><p align=\"justify\"><strong>Methods: </strong>A cross sectional study was carried out on Iraqi patients ( males and famales) in AL-Zahraa Consultant Center for Allergy and Asthma in Baghdad - Karkh, between Nov. 2013 - Apr. 2014 .The study included 60 asthmatic patients ( 6 - 45 years old) whom had allergy to house  mites antigens \" through skin test \",in addition to 20 apparently healthy persons as control group.A subcutaneous immunotherapy was given for 3 months, starting from diluted doses which were increased gradually. Clinical assessment was done depending on scoring of signs and symptoms, in addition to the medical history , clinical investigation, skin test, and pulmonary function test .<strong></strong></p><p align=\"justify\"><strong>Results:</strong> Study showed that asthma still affected all age group but tend to be higher in age group 31-45 years with male to female ratio 2:1. Family history to allergic disease play a major role 60% with increase prevalence of reactivity for indoor allergy (House Mites and Moulds).</p><p align=\"justify\">66.7% had positive skin reaction to House Mites which includes D1 ,D2 and D1+D2. The dust found to be one of main aggravating factors. Medical condition had shown significant improvement after three months of giving immunotherapy.<strong></strong></p><p align=\"justify\"><strong>Conclusion:</strong> Immunotherapy need to be considered as one of alternative treatment of allergic asthma decreasing the side effects and cost of different drugs used by these patients when given regularly to them, also detection of prevalent allergens in our local atmosphere and their concentration with detection of their seasonal distribution in different parts of our country is required.</p>","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121645525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical analysis of ureteroscopic holmium laser lithotripsy for the treatment of nephrolithiasis","authors":"Yansi Xue, Lei-Han Xu, Xiaojun Xu, Dukun Wang, Guo-Cheng Wang, Yi Chen","doi":"10.18282/cs.v1.i1.16","DOIUrl":"https://doi.org/10.18282/cs.v1.i1.16","url":null,"abstract":"The objective of the study is to evaluate the clinical value of ureteroscopic holmium laser lithotripsy for the treatment of nephrolithiasis. Clinical data of 44 patients treated for renal stones with polyscope modular flexible ureter- oscopic holmium laser lithotripsy from May 2014 to April 2015 were retrospectively analysed. Following the operation, F4.7 D-J stents were routinely indwelled for 4 weeks and catheterization for 1-3 days. A plain kidney, ureter, and blad- der (KUB) X-ray was performed on postoperative days too. A total of four success cases were determined following the first treatment. The remaining 40 cases were first placed with double-J stent and the surgery was performed one week later. Stone sizes between 0.8-4.0 cm in diameter were defined. The operation time for the treatment was 80-180 minutes. Patients were discharged within 3-5 days, and the double-J stent was removed within 1-3 months. 39 patients were found to be completely stone-free at approximately three months postoperatively. However, five patients were shown to have 11.1% of residual stones after treatment. No blood transfusion, septic shock, ureteral injury, or other complications were reported. Flexible ureteroscopic holmium laser lithotripsy is safe and effective for the treatment of nephrolithiasis. This approach could be a valuable choice for the treatment of patients with renal stones.","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134150422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causes and management of bleeding during laparoscopic colorectal cancer surgery","authors":"Ming Xu, Weiqiang Wu, Zengqiang Yang, Feng Gao","doi":"10.18282/RCSM.V1.I1.26","DOIUrl":"https://doi.org/10.18282/RCSM.V1.I1.26","url":null,"abstract":"In this paper, the causes of bleeding during laparoscopic colorectal surgery and the measures to solve it are discussed. 386 cases of laparoscopic colorectal cancer surgery in our hospital from January to December 2015 were selected. There were 17 cases of bleeding during surgery, which accounted for 4.4% of the total amount. 2 cases were converted to laparotomy, and 15 cases were surgery via laparoscopy. In the surgical process, improper surgery, lack of good laparoscopic anatomical structure of the cognitive level, and congenital anatomic variation may have caused the accidental bleeding during surgery. Corresponding measures should be taken to stop accidental bleeding.  ","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131080195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of HBV DNA by PCR and its application in clinical transfusion","authors":"Shunqing Li","doi":"10.18282/rcsm.v1.i1.13","DOIUrl":"https://doi.org/10.18282/rcsm.v1.i1.13","url":null,"abstract":" This study was to detect the hepatitis B virus (HBV) DNA copies in patients through blood transfusions; recessive carriers with HBsAg negative but HBV DNA positive were further studied to see the content and distribution of HBV in patients, and provide evidence for the clinical treatment. A total of 532 blood samples collected from July 2014 to July 2015 were tested for HBV-DNA viral load and hepatitis B serological markers using quantitative Polymerase Chain Reaction (qPCR) and serologic test (five serological markers of hepatitis B). The results showed that, 3 cases were HBV serology negative and the HBV-DNA viral load was in the range of 250-500 whereas only 1 case was HBsAb positive and the HBV-DNA viral load was above 500. qPCR, for detecting HBV DNA, together with serological routine test can effectively reduce HBV infection during transfusion and prevent medical disputes.","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"2006 13","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132679913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical effect of combined anterior and posterior approach surgery for cervical spondylotic myelopathy","authors":"Jiang Yanzhou, Fu Lianchong, Mu Yushan","doi":"10.18282/RCSM.V1.I1.55","DOIUrl":"https://doi.org/10.18282/RCSM.V1.I1.55","url":null,"abstract":"Objective: To evaluate the clinical efficacy of combined anterior and posterior approach surgery for patients with spinal type. Methods: 96 patients with cervical spondylosis were randomly selected among all patients admitted in our hospital from January 2013 to December 2015. They were evenly assigned to A, B or C group, 32 patients each.  Patients in Group A suffered from cervical myelopathy and were treated by combined anterior and posterior approach. Patients in Group B group suffered from cervical vertebra disease and accepted a cervical corpectomy decompression and a bone graft fusion internal fixation surgery. Patients in Group C accepted conventional posterior decompression and fusion surgery for lateral mass screw fixation. Postoperative follow-up, X-ray intervertebral stability and fusion, neurological function JOA score and clinical efficacy of the effective date were compared. Results: JOA scores of all three groups were improved after 6 months. After a year, patients in Group A, B and C scored (16.3 ± 1.83), (15.7 ± 1.15) and (15.59 ± 1.21), respectively. The pairwise score differences between any two groups were statistically significant (P < 0.05). After one year’s follow-up, the bone graft and internal fixation material had no signs of loosening, displacement or subsidence. The fusion rates of Group A, B and C reached 90.6%, 53.1% and 56.25%, respectively. Similarly, the pairwise differences in fusion rate between any two groups were statistically significant (P < 0.05). The clinical effectiveness was classified as apparent, effective, fair and invalid. The effective rates of Group A, B and C were 87.5%, 50% and 56.2%, respectively. The pairwise differences between any two groups were statistically significant (P < 0.05). Conclusion: Combined anterior and posterior approach surgery significantly improved the clinical efficacy than the other two surgeries.","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131700489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical study of endoscopic mucosal resection for digestive tract early cancer and precancerous lesions treatment","authors":"Huiji Peng","doi":"10.18282/RCSM.V1.I1.27","DOIUrl":"https://doi.org/10.18282/RCSM.V1.I1.27","url":null,"abstract":"The clinical effect of endoscopic mucosal resection (EMR) on the digestive tract of early cancer and precan-cerous lesions was analyzed. 63 patients with early gastrointestinal cancer and precancerous lesions treated in our hospital from January 2013 to May 2015 were recruited for this study. Patients were randomly divided into the observation group (32 cases) and the control group (31 cases). The control group underwent conventional surgical treatment, while  the observation group underwent EMR. Both groups were observed for the clinical effect. The curative resection rate was 100.0% (P > 0.05). The postoperative complication rate was 3.1% (1/32) in the observation group and 25.8% (8/31) in the control group. The operation time for the observation group was significantly shorter than the control group (P < 0.05). Subjects were followed up for 1 year. Both groups showed no primary tumor metastasis and recurrence (P > 0.05). EMR treatment showed good effect and significantly fewer complications in patients. ","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133829435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical analysis of ureteroscopic holmium laser lithotripsy for the treatment of nephrolithiasis","authors":"Xue Yansi, X. Lei, X. Xiaojun, Wang Dukun, Wang Guocheng, Chen yi","doi":"10.18282/rcsm.v1.i1.16","DOIUrl":"https://doi.org/10.18282/rcsm.v1.i1.16","url":null,"abstract":"The objective of the study is to evaluate the clinical value of ureteroscopic holmium laser lithotripsy for the treatment of nephrolithiasis. Clinical data of 44 patients treated for renal stones with polyscope modular flexible ureter- oscopic holmium laser lithotripsy from May 2014 to April 2015 were retrospectively analysed. Following the operation, F4.7 D-J stents were routinely indwelled for 4 weeks and catheterization for 1-3 days. A plain kidney, ureter, and blad- der (KUB) X-ray was performed on postoperative days too. A total of four success cases were determined following the first treatment. The remaining 40 cases were first placed with double-J stent and the surgery was performed one week later. Stone sizes between 0.8-4.0 cm in diameter were defined. The operation time for the treatment was 80-180 minutes. Patients were discharged within 3-5 days, and the double-J stent was removed within 1-3 months. 39 patients were found to be completely stone-free at approximately three months postoperatively. However, five patients were shown to have 11.1% of residual stones after treatment. No blood transfusion, septic shock, ureteral injury, or other complications were reported. Flexible ureteroscopic holmium laser lithotripsy is safe and effective for the treatment of nephrolithiasis. This approach could be a valuable choice for the treatment of patients with renal stones.","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130258843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosing ovarian masses by using nuclear magnetic resonance","authors":"E. Zhang","doi":"10.18282/RCSM.V1.I1.15","DOIUrl":"https://doi.org/10.18282/RCSM.V1.I1.15","url":null,"abstract":"In the research, nuclear magnetic resonance (NMR) was used to study and diagnose ovarian tumour. A total of 80 ovarian tumour patients who were admitted to the hospital from February 2014 to May 2016 were selected and randomly divided into 2 groups, 40 in the case group and 40 in the control group. The case group used NMR whereas the control group utilized B-mode ultrasound to compare the characteristics of tumor masses, accuracy, sensitivity, and specificity of the clinical diagnosis afterwards. The accuracy, sensitivity, specificity, and characteristics of tumour masses by NMR were 95.84%, 94.75%, 90.92%, and 100%, respectively, which were apparently higher than   those of the B-mode ultrasound scanning (64.28%, 77.78%, 75.08%, and 70.83%, respectively). Difference of each index among the four between the two methods was statistically significant (p < 0.05). Therefore, NMR is superior to ultrasound in diagnosing ovarian tumour. ","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128777381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical application of minimal invasive arthroscope on patella fracture surgery","authors":"B. Jiang, Lele Liao","doi":"10.18282/RCSM.V1.I1.12","DOIUrl":"https://doi.org/10.18282/RCSM.V1.I1.12","url":null,"abstract":"The aim of the research is to perform the application of minimal invasive arthroscope on patella fracture surgery. A total of 100 patients with the cases of patella fracture were selected from our hospital and the Second Xiangya Hospital’s Orthopaedic Ward. These patients were divided into ‘Observation Group’ and ‘Comparison Group’. The former was treated with traditional open surgery whereas the latter used the arthroscopic surgery. The postsurgical score indicated statistically significant differences (P < 0.05) in the Lysholm Knee and Oswestry Low Back pain scale. By performing arthroscopic surgery on patella fractures, the patients’ recovery was accelerated while the pain was greatly reduced, which in turn, improved the quality of patients’ life and provided valuable clinical value. ","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116980813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computer-assisted surgery navigation of pedicle screw insertion by standardized trainees","authors":"Ming-yong Liu, Liang Zhang, Jian-hua Zhao, P. Liu","doi":"10.18686/aem.v6.81","DOIUrl":"https://doi.org/10.18686/aem.v6.81","url":null,"abstract":"Objective: To assess the precision and efficiency computer-assisted surgery navigation of pedicle screw insertion by standardized trainees. Methods: From September 2013 to June 2016, 360 thoracic pedicle screws were inserted into 100 patients by standardized trainees (n = 30). Screws on the left side were inserted by hands (control group), while the other side were inserted under the guidance of computer-assistant navigation system (guided group). The insertion time and volume of blood lost by each screw were retrospectively analyzed. The precision ratio was assessed by computerized tomography (CT) scan after operation. Results: The time consumed in screw insertion was significantly shorter in the guided group than that in the control group. The blood lost volume was lesser in the guided group. Post-operation CT scan revealed higher precision in the guided group than that in the control group. Conclusion: Computer-assistant navigation system facilitates the learning of standardized trainees, and reduces the time-consuming and bleeding in thoracic pedicle screw insertion.","PeriodicalId":344347,"journal":{"name":"Reports in Clinical Studies and Medicine","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125577899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}