Journal of Neonatal Surgery最新文献_第2页

Caudal regression syndrome in a newborn in distress: A therapeutic challenge 窘迫新生儿尾椎退缩综合征：治疗难题

Journal of Neonatal Surgery Pub Date : 2024-02-26 DOI: 10.47338/jns.v13.1292

R. Lamiri, Ghada Habachi, N. Kechiche, Meriem Oumaima Beji, Hayet Ben Hmida, A. Ksia, M. Mekki, L. Sahnoun

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Staged repair of esophageal atresia, tracheoesophageal fistula, and duodenal atresia in a newborn 新生儿食管闭锁、气管食管瘘和十二指肠闭锁的分期修复术

Journal of Neonatal Surgery Pub Date : 2024-01-14 DOI: 10.47338/jns.v13.1261

Christos Tsakalidis, M. Lithoxopoulou, Nikolaos Gkiourtzis, Eftychia Drogouti, V. Mouravas, Ioannis Spyridakis, Elisavet Diamanti

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Somatostatin analog (octreotide) and sirolimus immunosuppressive therapy in the treatment of chyloperitoneum and chylothorax in newborns and infants 治疗新生儿和婴儿乳糜腹水和乳糜胸的体生长抑素类似物（奥曲肽）和西罗莫司免疫抑制疗法

Journal of Neonatal Surgery Pub Date : 2024-01-03 DOI: 10.47338/jns.v13.1240

A. Gurskaya, M. Sulavko, E. Ekimovskaya, R. Bayazitov, O. Nakovkin, I. Karnuta, A. Klepikova, Dinara Akhmedova, Ruslan A. Hagurov, G. Sagoyan, Yelena Dyakonova, A. Fisenko

{"title":"Somatostatin analog (octreotide) and sirolimus immunosuppressive therapy in the treatment of chyloperitoneum and chylothorax in newborns and infants","authors":"A. Gurskaya, M. Sulavko, E. Ekimovskaya, R. Bayazitov, O. Nakovkin, I. Karnuta, A. Klepikova, Dinara Akhmedova, Ruslan A. Hagurov, G. Sagoyan, Yelena Dyakonova, A. Fisenko","doi":"10.47338/jns.v13.1240","DOIUrl":"https://doi.org/10.47338/jns.v13.1240","url":null,"abstract":"Background: Chyloperitoneum (CP) and chylothorax (CT) are rare conditions that have a high mortality rate and unclear treatment options. Their incidence in neonates ranges from 1 in 20000 to 1 in 187000 live births. This study aims to evaluate the effectiveness of synthetic somatostatin analog (octreotide) and sirolimus therapy in treating chylous pleural and peritoneal collections in newborns and infants.\u0000Methods: We conducted a retrospective analysis of 10 children with either chylothorax or chyloperitoneum, treated in our department between 2018 and 2023. The study was approved by the Local Independent Ethics Committee of The National Medical Research Center of Children's Health, under Protocol №7, dated 11 May 2023. The parents voluntarily signed an informed consent form for the off-label use of the drug. We reviewed the medical records for demographic information, clinical presentation, management, and outcome.\u0000Results: Our study looked at patients aged between 0 and 5.5 months, with seven cases of chyloperitoneum and three cases of chylothorax. We initially used octreotide, which was then switched to sirolimus if there was no improvement. Octreotide was effective in five children after 10-18 days of treatment, while the effect of sirolimus was observed 8-14 days after starting treatment. One patient, who had a history of a giant omphalocele with primary closure, experienced complications after 8 weeks of sirolimus therapy, including bilateral knee arthritis, leukopenia, and lymphopenia. Fortunately, there were no fatal outcomes.\u0000Conclusion: Sirolimus therapy is effective in treating newborns with chylothorax or chyloperitoneum, with a low risk of complications even in those cases not responding to octreotide therapy. It is recommended that octreotide therapy should not exceed 10 days, after which sirolimus can be prescribed.","PeriodicalId":34201,"journal":{"name":"Journal of Neonatal Surgery","volume":"139 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139387424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Second-look surgery in a patient of malrotation with midgut volvulus 为一名中肠旋转不良患者实施的二诊手术

Journal of Neonatal Surgery Pub Date : 2024-01-03 DOI: 10.47338/jns.v13.1258

S. K. Gupta, Anand Pandey, R. Rai, N. Tyagi

引用次数: 0

Neutrophil to Lymphocyte ratio: A promising tool in neonatal appendicitis diagnosis 中性粒细胞与淋巴细胞比率：诊断新生儿阑尾炎的有效工具

Journal of Neonatal Surgery Pub Date : 2023-12-31 DOI: 10.47338/jns.v13.1247

Emine Burcu Cigsar Kuzu

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Perioperative fluid and electrolyte management in surgical neonates 手术新生儿围手术期的液体和电解质管理

Journal of Neonatal Surgery Pub Date : 2023-12-31 DOI: 10.47338/jns.v13.1225

Nitin James Peters, Shivani Dogra, Sandhya Yaddanapudi, Jai Kumar Mahajan

引用次数: 0

Amyand hernia with perforated appendix simulating as testicular torsion in a neonate: A case report 新生儿睾丸扭转伴阑尾穿孔的疝：病例报告

Journal of Neonatal Surgery Pub Date : 2023-12-31 DOI: 10.47338/jns.v13.1252

O. Edan

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Artificial intelligence and writing: What ChatGPT says? 人工智能与写作：ChatGPT 是怎么说的？

Journal of Neonatal Surgery Pub Date : 2023-12-31 DOI: 10.47338/jns.v13.1280

Bilal Mirza

引用次数: 0

A case of anorectal malformation with human tail 一例人尾肛门畸形病例

Journal of Neonatal Surgery Pub Date : 2023-12-31 DOI: 10.47338/jns.v13.1270

Omar Ajaj

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Predictors of postoperative mortality among neonates after major-risk surgery: A one-year experience from a Tunisian hospital 重大风险手术后新生儿术后死亡率的预测因素：突尼斯一家医院的一年经验

Journal of Neonatal Surgery Pub Date : 2023-12-31 DOI: 10.47338/jns.v13.1275

Manel Kammoun, Anouar Jarraya, Hechem Bradai, Hind Ketata, Hasna Bouchaira, Olfa Cherif, Amel Ben Hamed, Faiza Safi, R. Mhiri

{"title":"Predictors of postoperative mortality among neonates after major-risk surgery: A one-year experience from a Tunisian hospital","authors":"Manel Kammoun, Anouar Jarraya, Hechem Bradai, Hind Ketata, Hasna Bouchaira, Olfa Cherif, Amel Ben Hamed, Faiza Safi, R. Mhiri","doi":"10.47338/jns.v13.1275","DOIUrl":"https://doi.org/10.47338/jns.v13.1275","url":null,"abstract":"Background: Neonatal surgery in developing countries remains a high-risk modality p and its outcomes depend on various patient-related, system-related, and management-related factors. This study aims to describe our experience in managing newborns requiring surgical interventions and to investigate the primary predictors of postoperative mortality. Methods: In this observational study, we included all newborns aged less than 28 days who underwent surgery in the pediatric surgery department under general anesthesia with tracheal intubation for major-risk surgery. Patients were categorized into two groups based on the outcome (survival or death) during the two months following surgery. Following a comparison of the two groups, univariable and multivariable logistic regression analyses were conducted to explore predictors of perioperative mortality among neonates. Results: Sixty-seven newborns were included in this study, with an early mortality incidence of 28.3%. Anesthesia management did not impact neonatal mortality. The main predictors of neonatal mortality were revision surgery [aOR=35.5; 95% CI: 1.33- 94.1], surgery duration ≥ 120 minutes [aOR=36.5; 95% CI: 1.48- 312], preoperative mechanical ventilation [aOR=3.88; 95% CI: 1.12- 30.8], and the occurrence of perioperative adverse events [aOR=5.7; 95% CI: 1–29.5] or postoperative surgical complications [aOR=32.5; 95% CI: 1.05–101]. Conclusion: The early mortality rate after major neonatal surgery remains high in our department. It appears that preoperative poor conditions can elevate the risk. Additionally, major-risk surgeries requiring prolonged procedures and revision surgery, along with the incidence of postoperative infections, significantly increase the risk of neonatal mortality.","PeriodicalId":34201,"journal":{"name":"Journal of Neonatal Surgery","volume":"97 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139131525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0